PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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3GI1	Crystal Structure of the laminin-binding protein Lbp of Streptococcus pyogenes 分子名称: Laminin-binding protein of group A streptococci, ZINC ION 著者 Linke, C, Caradoc-Davies, T.T, Young, P.G, Proft, T, Baker, E.N. 登録日 2009-03-04 公開日 2009-08-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The laminin-binding protein Lbp from Streptococcus pyogenes is a zinc receptor J.Bacteriol., 191, 2009
4J8T	Engineered Digoxigenin binder DIG10.2 分子名称: DIGOXIGENIN, Engineered Digoxigenin binder protein DIG10.2 著者 Stoddard, B.L, Doyle, L.A. 登録日 2013-02-14 公開日 2013-06-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Computational design of ligand-binding proteins with high affinity and selectivity. Nature, 501, 2013
4J8N	Aurora A Kinase Apo 分子名称: Aurora kinase A 著者 Meyerowitz, J.G, Gustafson, W.C, Shokat, K.M, Weiss, W.A. 登録日 2013-02-14 公開日 2014-09-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.135 Å) 主引用文献 Drugging MYCN through an Allosteric Transition in Aurora Kinase A. Cancer Cell, 26, 2014
4J9H	Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 at pH 8 分子名称: P7, SULFATE ION, Tyrosine-protein kinase ABL1 著者 Camara-Artigas, A. 登録日 2013-02-16 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 To be Published
2PY6	Crystal structure of Methyltransferase FkbM (YP_546752.1) from Methylobacillus flagellatus KT at 2.20 A resolution 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2007-05-15 公開日 2007-05-29 最終更新日 2023-01-25 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of Methyltransferase FkbM (YP_546752.1) from Methylobacillus flagellatus KT at 2.20 A resolution To be published
4JBQ	Novel Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules 分子名称: Aurora Kinase A, CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE 著者 Wu, J.S, Leou, J.S, Peng, Y.H, Hsueh, C.C, Hsieh, H.P, Wu, S.Y. 登録日 2013-02-20 公開日 2013-06-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules. Proc.Natl.Acad.Sci.USA, 110, 2013
2Q03	Crystal structure of uncharacterized protein (YP_563039.1) from Shewanella denitrificans OS217 at 1.80 A resolution 分子名称: GLYCEROL, Uncharacterized protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2007-05-18 公開日 2007-05-29 最終更新日 2023-01-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of uncharacterized protein (YP_563039.1) from Shewanella denitrificans OS217 at 1.80 A resolution To be published
4JBI	2.35A resolution structure of NADPH bound thermostable alcohol dehydrogenase from Pyrobaculum aerophilum 分子名称: Alcohol dehydrogenase (Zinc), NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ZINC ION 著者 Lovell, S, Battaile, K.P, Vitale, A, Throne, N, Hu, X, Shen, M, D'Auria, S, Auld, D.S. 登録日 2013-02-19 公開日 2013-06-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Physicochemical Characterization of a Thermostable Alcohol Dehydrogenase from Pyrobaculum aerophilum. Plos One, 8, 2013
4JDD	14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface 分子名称: 14-3-3 protein sigma, Estrogen receptor Peptide, FUSICOCCIN 著者 Bier, D, Ottmann, C. 登録日 2013-02-25 公開日 2013-05-15 最終更新日 2017-06-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
4JC7	Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis 分子名称: Leukotriene C4 synthase, NICKEL (II) ION, PALMITIC ACID, ... 著者 Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z. 登録日 2013-02-21 公開日 2014-01-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM. J.Biol.Chem., 289, 2014
3GLC	Crystal Structure of E. coli LsrF in complex with Ribose-5-phosphate 分子名称: Aldolase lsrF, RIBOSE-5-PHOSPHATE 著者 Miller, S.T, Diaz, Z.C. 登録日 2009-03-11 公開日 2009-09-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of the Escherichia coli autoinducer-2 processing protein LsrF. Plos One, 4, 2009
2Q9K	Crystal structure of a putative oxidoreductase (exig_1997) from exiguobacterium sibiricum 255-15 at 1.59 A resolution 分子名称: UNKNOWN LIGAND, Uncharacterized protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2007-06-12 公開日 2007-06-19 最終更新日 2023-01-25 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Crystal structure of conserved uncharacterized protein (ZP_00539648.1) from Exiguobacterium sp. 255-15 at 1.59 A resolution To be published
4JFI	Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with compound 1-[(9S,13R,13aR)-1,3-dimethoxy-8-oxo-5,8,9,10,11,12,13,13a-octahydro-6H-9,13-epiminoazocino[2,1-a]isoquinolin-14-yl]-2-(3,4,5-trimethoxyphenyl)ethane-1,2-dione 分子名称: 1-[(9S,13R,13aR)-1,3-dimethoxy-8-oxo-5,8,9,10,11,12,13,13a-octahydro-6H-9,13-epiminoazocino[2,1-a]isoquinolin-14-yl]-2-(3,4,5-trimethoxyphenyl)ethane-1,2-dione, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Wang, Y, Kirschner, A, Fabian, A, Gopalakrishnan, R, Kress, C, Hoogeland, B, Koch, U, Kozany, C, Bracher, A, Hausch, F. 登録日 2013-02-28 公開日 2013-08-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Increasing the efficiency of ligands for FK506-binding protein 51 by conformational control. J.Med.Chem., 56, 2013
4JKM	Crystal Structure of Clostridium perfringens beta-glucuronidase 分子名称: Beta-glucuronidase, Maltose-binding periplasmic protein 著者 Wallace, B.D, Redinbo, M.R. 登録日 2013-03-09 公開日 2014-09-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.263 Å) 主引用文献 Structure and Inhibition of Microbiome beta-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity. Chem.Biol., 22, 2015
4JL0	Crystal structure of PcrH in complex with the chaperone binding region of PopB 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PopB, Regulatory protein PcrH 著者 Discola, K.F, Forster, A, Simorre, J.P, Attree, I, Dessen, A, Job, V. 登録日 2013-03-12 公開日 2013-12-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Membrane and Chaperone Recognition by the Major Translocator Protein PopB of the Type III Secretion System of Pseudomonas aeruginosa. J.Biol.Chem., 289, 2014
4HFQ	Crystal structure of UDP-X diphosphatase 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... 著者 Duong-Ly, K.C, Amzel, L.M, Gabelli, S.B. 登録日 2012-10-05 公開日 2013-08-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 A UDP-X diphosphatase from Streptococcus pneumoniae hydrolyzes precursors of peptidoglycan biosynthesis. Plos One, 8, 2013
2QOK	Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:S768A triple mutant 分子名称: BETA-MERCAPTOETHANOL, Ephrin receptor 著者 Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2007-07-20 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3). Structure, 16, 2008
2Q8U	CRYSTAL STRUCTURE OF MRE11 FROM THERMOTOGA MARITIMA MSB8 (TM1635) AT 2.20 A RESOLUTION 分子名称: Exonuclease, putative 著者 Joint Center for Structural Genomics (JCSG) 登録日 2007-06-11 公開日 2007-06-26 最終更新日 2023-01-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair. J.Mol.Biol., 397, 2010
4H5L	Crystal Structure of Toscana Virus Nucleocapsid Protein Hexamer 分子名称: Nucleoprotein 著者 Raymond, D.D, Smith, J.L. 登録日 2012-09-18 公開日 2012-11-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Phleboviruses encapsidate their genomes by sequestering RNA bases. Proc.Natl.Acad.Sci.USA, 109, 2012
2QOC	Human EphA3 kinase domain, phosphorylated, AMP-PNP bound structure 分子名称: BETA-MERCAPTOETHANOL, Ephrin receptor, MAGNESIUM ION, ... 著者 Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2007-07-20 公開日 2007-08-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3). Structure, 16, 2008
3DP3	Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3q 分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 4-tert-butyl-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide, BENZAMIDINE, ... 著者 Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H. 登録日 2008-07-07 公開日 2009-05-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination. J.Med.Chem., 52, 2009
4GNL	Structure of rat cytosolic PEPCK Ld_2g in complex with PEP and GDP 分子名称: GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... 著者 Johnson, T.A, Holyoak, T. 登録日 2012-08-17 公開日 2013-07-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
5RSK	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINC000901381520_N3 分子名称: 3-[(3-methoxy-1,2-oxazol-5-yl)methyl]-3H-purin-6-amine, Non-structural protein 3 著者 Correy, G.J, Young, I.D, Thompson, M.C, Fraser, J.S. 登録日 2020-09-28 公開日 2020-12-16 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Sci Adv, 7, 2021
2QOQ	Human EphA3 kinase and juxtamembrane region, base, AMP-PNP bound structure 分子名称: Ephrin receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Loppnau, P, Allali-Hassani, A, Structural Genomics Consortium (SGC) 登録日 2007-07-20 公開日 2007-10-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3). Structure, 16, 2008
5RSZ	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINC000004218283 分子名称: 1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID, Non-structural protein 3 著者 Correy, G.J, Young, I.D, Thompson, M.C, Fraser, J.S. 登録日 2020-09-28 公開日 2020-12-16 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.02 Å) 主引用文献 Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Sci Adv, 7, 2021

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