PDB: 5434 件ウェブページステータス検索Chemie searchBIRD

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7MNV	Crystal Structure of the ZnF8 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP 分子名称: E3 SUMO-protein ligase RanBP2, GLYCEROL, GTP-binding nuclear protein Ran, ... 著者 Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. 登録日 2021-05-01 公開日 2022-06-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
7MNX	Crystal Structure of Nup358/RanBP2 Ran-binding domain 2 in complex with Ran-GPPNHP 分子名称: E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, MAGNESIUM ION, ... 著者 Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. 登録日 2021-05-01 公開日 2022-06-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
7MO4	Crystal Structure of the ZnF3 of Nucleoporin NUP153 in complex with Ran-GDP, resolution 2.4 Angstrom 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. 登録日 2021-05-01 公開日 2022-06-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
7MNY	Crystal Structure of Nup358/RanBP2 Ran-binding domain 3 in complex with Ran-GPPNHP 分子名称: E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, MAGNESIUM ION, ... 著者 Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. 登録日 2021-05-01 公開日 2022-06-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
7MO2	Crystal Structure of the ZnF2 of Nucleoporin NUP153 in complex with Ran-GDP 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. 登録日 2021-05-01 公開日 2022-06-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
7MO5	Crystal Structure of the ZnF4 of Nucleoporin NUP153 in complex with Ran-GDP 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. 登録日 2021-05-01 公開日 2022-06-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
7MO3	Crystal Structure of the ZnF3 of Nucleoporin NUP153 in complex with Ran-GDP, resolution 2.05 Angstrom 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. 登録日 2021-05-01 公開日 2022-06-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
6K3E	LSD1/Co-Rest structure with an inhibitor 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-PCPA derivative, ... 著者 Wang, J. 登録日 2019-05-17 公開日 2020-05-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.87 Å) 主引用文献 LSD1/Co-Rest structure with an inhibitor To Be Published
7MR9	Crystal structure of the first bromodomain (BD1) of human BRD4 bound to NC-II-153 分子名称: 1,2-ETHANEDIOL, 2-methyl-4-[3-(2-oxopyrrolidin-1-yl)phenyl]isoquinolin-1(2H)-one, Bromodomain-containing protein 4 著者 Chan, A, Schonbrunn, E. 登録日 2021-05-07 公開日 2022-08-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J.Med.Chem., 65, 2022
7MRA	Crystal structure of the first bromodomain (BD1) of human BRD4 bound to NC-II-259 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, N-[3-(2-methyl-1-oxo-1,2-dihydroisoquinolin-4-yl)phenyl]ethanesulfonamide 著者 Chan, A, Schonbrunn, E. 登録日 2021-05-07 公開日 2022-08-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J.Med.Chem., 65, 2022
7MRB	Crystal structure of the first bromodomain (BD1) of human BRD4 bound to NC-III-53 分子名称: Bromodomain-containing protein 4, N-[4-(4-chlorophenoxy)-3-(2-methyl-1-oxo-1,2-dihydroisoquinolin-4-yl)phenyl]ethanesulfonamide 著者 Chan, A, Schonbrunn, E. 登録日 2021-05-07 公開日 2022-08-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J.Med.Chem., 65, 2022
6KZH	14-3-3 protein in Complex with CIC S173 phosphorylated peptide 分子名称: 14-3-3 protein theta, CIC pS173 peptide 著者 Wen, Y, Shao, Y. 登録日 2019-09-24 公開日 2020-09-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.645 Å) 主引用文献 14-3-3 protein in Complex with CIC S173 phosphorylated peptide To Be Published
7MBH	Structure of Human Enolase 2 in complex with phosphoserine 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Gamma-enolase, ... 著者 Leonard, P.G, Hicks, K.G, Rutter, J. 登録日 2021-03-31 公開日 2022-11-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase. Science, 379, 2023
5XJT	Crystal Structure of the Gemin2-binding domain of SMN, Gemin2 in Complex with SmD1(1-82)/D2.R61A/F/E/G from Human 分子名称: Gem-associated protein 2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... 著者 Yi, H, Zhang, R. 登録日 2017-05-04 公開日 2018-07-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Structures of 7S mutant complexes To Be Published
5XM0	The mouse nucleosome structure containing H2A, H2B type3-A, H3.3, and H4 分子名称: DNA (146-MER), Histone H2A type 1-B, Histone H2B type 3-A, ... 著者 Taguchi, H, Horikoshi, N, Kurumizaka, H. 登録日 2017-05-12 公開日 2018-03-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.874 Å) 主引用文献 Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration. Nat Commun, 9, 2018
6I13	CRYSTAL STRUCTURE OF FASCIN IN COMPLEX WITH COMPOUND 7 分子名称: 1,2-ETHANEDIOL, 2-[(3-chlorophenyl)methyl]-~{N}-(1-methylpyrazol-4-yl)-1-oxidanylidene-isoquinoline-4-carboxamide, ACETATE ION, ... 著者 Schuettelkopf, A.W. 登録日 2018-10-27 公開日 2019-02-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents. Bioorg.Med.Chem.Lett., 29, 2019
6I42	Structure of the alpha-Synuclein PreNAC/Cyclophilin A-complex 分子名称: Alpha-synuclein, Peptidyl-prolyl cis-trans isomerase A 著者 Favretto, F, Zweckstetter, M, Becker, S. 登録日 2018-11-08 公開日 2020-02-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 The Molecular Basis of the Interaction of Cyclophilin A with alpha-Synuclein. Angew.Chem.Int.Ed.Engl., 59, 2020
6I17	CRYSTAL STRUCTURE OF FASCIN IN COMPLEX WITH COMPOUND 24 分子名称: 1,2-ETHANEDIOL, 2-[(3,4-dichlorophenyl)methyl]-~{N}-(1-methylpyrazol-4-yl)-1-oxidanylidene-6-piperidin-4-yl-2,7-naphthyridine-4-carboxamide, ACETATE ION, ... 著者 Schuettelkopf, A.W. 登録日 2018-10-27 公開日 2019-02-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents. Bioorg.Med.Chem.Lett., 29, 2019
6I2U	Aurora-A kinase domain in complex with Coenzyme A 分子名称: Aurora kinase A, COENZYME A, DI(HYDROXYETHYL)ETHER, ... 著者 Burgess, S.G, Bayliss, R. 登録日 2018-11-02 公開日 2019-10-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Covalent Aurora A regulation by the metabolic integrator coenzyme A. Redox Biol, 28, 2019
6I18	CRYSTAL STRUCTURE OF FASCIN IN COMPLEX WITH BDP-13176 分子名称: 1,2-ETHANEDIOL, 5-[(3,4-dichlorophenyl)methyl]-4-oxidanylidene-1-piperidin-4-yl-~{N}-pyridin-4-yl-pyrazolo[4,3-c]pyridine-7-carboxamide, ACETATE ION, ... 著者 Schuettelkopf, A.W. 登録日 2018-10-27 公開日 2019-02-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents. Bioorg.Med.Chem.Lett., 29, 2019
6A38	MVM NS2 NES in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... 著者 Sun, Q, Li, Y. 登録日 2018-06-15 公開日 2019-06-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
6J44	Crystal structure of the redefined DNA-binding domain of human XPA 分子名称: DNA repair protein complementing XP-A cells, ZINC ION 著者 Lian, F.M, Yang, X, Yang, W, Jiang, Y.L, Qian, C. 登録日 2019-01-07 公開日 2019-05-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Structural characterization of the redefined DNA-binding domain of human XPA. Biochem.Biophys.Res.Commun., 514, 2019
6L1R	Crystal structure of N-terminal domain of human SSRP1 分子名称: FACT complex subunit SSRP1 著者 Li, H.Y, Hu, T.T, Dou, Y.S, Su, D. 登録日 2019-09-30 公開日 2020-09-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7984395 Å) 主引用文献 Crystal structure of N-terminal domain of human SSRP1 To Be Published
6LGK	Crystal structure of an oxido-reductase with mutation 分子名称: Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION 著者 Yang, Y, Lei, J, Yin, L. 登録日 2019-12-05 公開日 2020-12-09 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of an oxido-reductase with mutation To Be Published
6LGJ	Crystal structure of an oxido-reductase 分子名称: Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Yang, Y, Lei, J, Yin, L. 登録日 2019-12-05 公開日 2020-12-09 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of an oxido-reductase To be published

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