PDB: 215264 件ウェブページステータス検索Chemie searchBIRD

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5QIK	TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D) IN COMPLEX WITH N-{4-[3-(6-fluoropyridin-3-yl)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl]pyridin-2-yl}acetamide 分子名称: GLYCEROL, N-{4-[3-(6-fluoropyridin-3-yl)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl]pyridin-2-yl}acetamide, TGF-beta receptor type-1 著者 Sheriff, S. 登録日 2018-08-05 公開日 2018-10-31 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Discovery of 4-Azaindole Inhibitors of TGF beta RI as Immuno-oncology Agents. ACS Med Chem Lett, 9, 2018
3P7J	Drosophila HP1a chromo shadow domain 分子名称: GLYCEROL, Heterochromatin protein 1 著者 Kim, D, Chruszcz, M, Minor, W, Khorasanizadeh, S. 登録日 2010-10-12 公開日 2011-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The HP1a Disordered C Terminus and Chromo Shadow Domain Cooperate to Select Target Peptide Partners. Chembiochem, 12, 2011
3P4S	Crystal structure of Menaquinol:fumarate oxidoreductase in complex with a 3-nitropropionate adduct 分子名称: 3-NITROPROPANOIC ACID, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... 著者 Tomasiak, T.M, Archuleta, T.L, Andrell, J, Luna-Chavez, C, Davis, T.A, Sarwar, M, Ham, A.J, McDonald, W.H, Yankowskaya, V, Stern, H.A, Johnston, J.N, Maklashina, E, Cecchini, G, Iverson, T.M. 登録日 2010-10-07 公開日 2010-12-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase. J.Biol.Chem., 286, 2011
4EPV	Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-mediated Activation 分子名称: 2-(1H-indol-3-ylmethyl)-1H-imidazo[4,5-c]pyridine, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Sun, Q, Burke, J.P, Phan, J, Burns, M.C, Olejniczak, E.T, Waterson, A.G, Lee, T, Rossanese, O.W, Fesik, S.W. 登録日 2012-04-17 公開日 2012-05-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation. Angew.Chem.Int.Ed.Engl., 51, 2012
1TNP	STRUCTURES OF THE APO AND CALCIUM TROPONIN-C REGULATORY DOMAINS: THE MUSCLE CONTRACTION SWITCH 分子名称: TROPONIN-C (APO) 著者 Gagne, S.M, Sykes, B.D. 登録日 1995-07-07 公開日 1995-10-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structures of the troponin C regulatory domains in the apo and calcium-saturated states. Nat.Struct.Biol., 2, 1995
2OC2	Structure of testis ACE with RXPA380 分子名称: Angiotensin-converting enzyme, somatic isoform, CHLORIDE ION, ... 著者 Corradi, H.R, Anthony, C.S, Schwager, S.L, Redelinghuys, P, Georgiadis, D, Dive, V, Acharya, K.R, Sturrock, E.D. 登録日 2006-12-20 公開日 2007-05-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The structure of testis angiotensin-converting enzyme in complex with the C domain-specific inhibitor RXPA380. Biochemistry, 46, 2007
4OK3	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 7 [[1-(3-chlorobenzyl)-1H-indol-3-yl]acetic acid] 分子名称: CALCIUM ION, Serine protease NS3, [1-(3-chlorobenzyl)-1H-indol-3-yl]acetic acid 著者 Padyana, A.K. 登録日 2014-01-21 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus. J.Med.Chem., 57, 2014
4OK6	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 13 [[1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid] 分子名称: CALCIUM ION, Serine protease NS3, [1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid 著者 Padyana, A.K. 登録日 2014-01-21 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus. J.Med.Chem., 57, 2014
1TEC	CRYSTALLOGRAPHIC REFINEMENT BY INCORPORATION OF MOLECULAR DYNAMICS. THE THERMOSTABLE SERINE PROTEASE THERMITASE COMPLEXED WITH EGLIN-C 分子名称: CALCIUM ION, EGLIN C, SODIUM ION, ... 著者 Gros, P, Dijkstra, B.W, Hol, W.G.J. 登録日 1989-05-24 公開日 1989-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystallographic refinement by incorporation of molecular dynamics: thermostable serine protease thermitase complexed with eglin c. Acta Crystallogr.,Sect.B, 45, 1989
4F4X	Y-family DNA polymerase chimera Dbh-Dpo4-Dpo4 #2 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*CP*AP*CP*TP*GP*AP*TP*CP*GP*GP*GP*C)-3'), ... 著者 Pata, J.D, Wilson, R.C. 登録日 2012-05-11 公開日 2013-01-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.049 Å) 主引用文献 Y-family polymerase conformation is a major determinant of fidelity and translesion specificity. Structure, 21, 2013
5OGI	Complex of a binding protein and human adenovirus C 5 hexon 分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... 著者 Schmid, M, Ernst, P, Honegger, A, Suomalainen, M, Zimmermann, M, Braun, L, Stauffer, S, Thom, C, Dreier, B, Eibauer, M, Kipar, A, Vogel, V, Greber, U.F, Medalia, O, Plueckthun, A. 登録日 2017-07-13 公開日 2018-02-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control. Nat Commun, 9, 2018
4F4W	Y-family DNA polymerase chimera Dbh-Dpo4-Dpo4 #1 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*CP*AP*CP*TP*GP*AP*TP*CP*GP*GP*C)-3'), ... 著者 Pata, J.D, Wilson, R.C. 登録日 2012-05-11 公開日 2013-01-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.898 Å) 主引用文献 Y-family polymerase conformation is a major determinant of fidelity and translesion specificity. Structure, 21, 2013
1PIC	PHOSPHATIDYLINOSITOL 3-KINASE, P85-ALPHA SUBUNIT: C-TERMINAL SH2 DOMAIN COMPLEXED WITH A TYR751 PHOSPHOPEPTIDE FROM THE PDGF RECEPTOR, NMR, MINIMIZED MEAN STRUCTURE 分子名称: BETA-PLATELET-DERIVED GROWTH FACTOR RECEPTOR, PHOSPHATIDYLINOSITOL 3-KINASE 著者 Breeze, A.L, Kara, B.V, Barratt, D.G, Anderson, M, Smith, J.C, Luke, R.W, Best, J.R, Cartlidge, S.A. 登録日 1997-06-23 公開日 1997-09-17 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Structure of a specific peptide complex of the carboxy-terminal SH2 domain from the p85 alpha subunit of phosphatidylinositol 3-kinase. EMBO J., 15, 1996
1CTF	STRUCTURE OF THE C-TERMINAL DOMAIN OF THE RIBOSOMAL PROTEIN L7/L12 FROM ESCHERICHIA COLI AT 1.7 ANGSTROMS 分子名称: RIBOSOMAL PROTEIN L7/L12, SULFATE ION 著者 Leijonmarck, M, Liljas, A. 登録日 1986-09-02 公開日 1987-01-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of the C-terminal domain of the ribosomal protein L7/L12 from Escherichia coli at 1.7 A. J.Mol.Biol., 195, 1987
1CMQ	SMALL MOLECULE BINDING TO AN ARTIFICIALLY CREATED CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE 分子名称: CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE 著者 Fitzgerald, M.M, Mcree, D.E, Churchill, M.J, Goodin, D.B. 登録日 1993-11-23 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Small molecule binding to an artificially created cavity at the active site of cytochrome c peroxidase. Biochemistry, 33, 1994
3SGD	Crystal structure of the mouse mAb 17.2 分子名称: CALCIUM ION, Heavy Chain, Light Chain 著者 Pizarro, J.C, Boulot, G, Hontebeyrie, M, Bentley, G.A. 登録日 2011-06-14 公開日 2011-11-09 最終更新日 2013-01-23 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Crystal structure of the complex mAb 17.2 and the C-terminal region of Trypanosoma cruzi P2 Beta protein: implications in cross-reactivity Plos Negl Trop Dis, 5, 2011
1UKK	Structure of Osmotically Inducible Protein C from Thermus thermophilus 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Osmotically Inducible Protein C 著者 Rehse, P.H, Kuramitsu, S, Yokoyama, S, Miyano, M, Tahirov, T.H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-08-24 公開日 2004-05-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystallographic Structure and Biochemical Analysis of the Thermus thermophilus Osmotically Inducible Protein C J.MOL.BIOL., 338, 2004
2PLE	NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE 分子名称: PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF 著者 Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D. 登録日 1994-08-19 公開日 1995-01-26 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Cell(Cambridge,Mass.), 77, 1994
1CMP	SMALL MOLECULE BINDING TO AN ARTIFICIALLY CREATED CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE 分子名称: 2,3-DIMETHYLIMIDAZOLIUM ION, CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE 著者 Fitzgerald, M.M, Mcree, D.E, Churchill, M.J, Goodin, D.B. 登録日 1993-11-23 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Small molecule binding to an artificially created cavity at the active site of cytochrome c peroxidase. Biochemistry, 33, 1994
2Q5Y	Crystal Structure of the C-terminal domain of hNup98 分子名称: Nuclear pore complex protein Nup96, Nuclear pore complex protein Nup98 著者 Sun, Y, Guo, H.C. 登録日 2007-06-03 公開日 2008-10-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural constraints on autoprocessing of the human nucleoporin Nup98. Protein Sci., 17, 2008
2BNW	Structural basis for cooperative binding of Ribbon-Helix-Helix Omega repressor to direct DNA heptad repeats 分子名称: 5'-D(*CP*TP*TP*GP*TP*GP*AP*TP*TP*TP *GP*TP*GP*AP*TP*TP*CP*G)-3', 5'-D(*GP*AP*AP*TP*CP*AP*CP*AP*AP*AP *TP*CP*AP*CP*AP*AP*GP*C)-3', ORF OMEGA 著者 Weihofen, W.A, Cicek, A, Pratto, F, Alonso, J.C, Saenger, W. 登録日 2005-04-05 公開日 2006-03-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structures of Omega Repressors Bound to Direct and Inverted DNA Repeats Explain Modulation of Transcription. Nucleic Acids Res., 34, 2006
4K08	Periplasmic sensor domain of chemotaxis protein, Adeh_3718 分子名称: ACETATE ION, Methyl-accepting chemotaxis sensory transducer, ZINC ION 著者 Pokkuluri, P.R, Mack, J.C, Bearden, J, Rakowski, E, Schiffer, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2013-04-03 公開日 2013-07-17 最終更新日 2015-04-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Analysis of periplasmic sensor domains from Anaeromyxobacter dehalogenans 2CP-C: structure of one sensor domain from a histidine kinase and another from a chemotaxis protein. Microbiologyopen, 2, 2013
3PA8	Structure of the C. difficile TcdB cysteine protease domain in complex with a peptide inhibitor 分子名称: CALCIUM ION, INOSITOL HEXAKISPHOSPHATE, N-acetylglycyl-N-[(3S)-1-hydroxy-5-methyl-2-oxohexan-3-yl]-L-serinamide, ... 著者 Lupardus, P.J, Garcia, K.C. 登録日 2010-10-18 公開日 2010-12-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Rational design of inhibitors and activity-based probes targeting Clostridium difficile virulence factor TcdB. Chem.Biol., 17, 2010
1A2I	SOLUTION STRUCTURE OF DESULFOVIBRIO VULGARIS (HILDENBOROUGH) FERROCYTOCHROME C3, NMR, 20 STRUCTURES 分子名称: CYTOCHROME C3, HEME C 著者 Messias, A.C, Kastrau, D.H.K, Costa, H.S, Legall, J, Turner, D.L, Santos, H, Xavier, A.V. 登録日 1998-01-05 公開日 1998-07-08 最終更新日 2022-02-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of Desulfovibrio vulgaris (Hildenborough) ferrocytochrome c3: structural basis for functional cooperativity. J.Mol.Biol., 281, 1998
2PLD	NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE 分子名称: PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF 著者 Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D. 登録日 1994-08-19 公開日 1995-01-26 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Cell(Cambridge,Mass.), 77, 1994

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