PDB: 8697 件ウェブページステータス検索Chemie searchBIRD

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1UVN	The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 ca2+ inhibition complex 分子名称: 5'-R(*UP*UP*UP*UP*CP*CP)-3', CALCIUM ION, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. 登録日 2004-01-21 公開日 2004-02-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
1UVL	The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 5nt RNA. Conformation B 分子名称: 5'-R(*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase 著者 Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. 登録日 2004-01-21 公開日 2004-02-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
1UVK	The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 dead-end complex 分子名称: GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. 登録日 2004-01-21 公開日 2004-02-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
1ARO	T7 RNA POLYMERASE COMPLEXED WITH T7 LYSOZYME 分子名称: MERCURY (II) ION, T7 LYSOZYME, T7 RNA POLYMERASE 著者 Steitz, T, Jeruzalmi, D. 登録日 1997-08-08 公開日 1998-10-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of T7 RNA polymerase complexed to the transcriptional inhibitor T7 lysozyme. EMBO J., 17, 1998
3N6L	The crystal structure of RNA-dependent RNA polymerase of EV71 virus 分子名称: NICKEL (II) ION, RNA-dependent RNA polymerase 著者 Wu, Y, Rao, Z.H. 登録日 2010-05-26 公開日 2011-06-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China. Protein Cell, 1, 2010
4QJF	X-ray crystal structure of Thermocuccus kodakarensis RNA polymerase Rpp4/Rpo7 (RpoF/RpoE) complex 分子名称: DNA-directed RNA polymerase, subunit E', subunit F 著者 Murakami, K.S. 登録日 2014-06-03 公開日 2014-10-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.312 Å) 主引用文献 Crystal structure of euryarchaeal RNA polymerase and insight into the evolution of RNA polymerase II structure Nat.Commun., 2014
1ONV	NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNAP II CTD Phosphatase FCP1 分子名称: Transcription initiation factor IIF, alpha subunit, serine phosphatase FCP1a 著者 Nguyen, B.D, Abbott, K.L, Potempa, K, Kobor, M.S, Archambault, J, Greenblatt, J, Legault, P, Omichinski, J.G. 登録日 2003-03-02 公開日 2003-05-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1 Proc.Natl.Acad.Sci.USA, 100, 2003
2JLF	STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA- DEPENDENT RNA POLYMERASE 分子名称: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE 著者 Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. 登録日 2008-09-08 公開日 2008-11-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase. Nucleic Acids Res., 36, 2008
7RIL	Crystal structure of hairpin polyamide Py-Im 1 bound to 5' CCTGACCAGG 分子名称: 3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[(1-methyl-4-{[1-methyl-4-({1-methyl-4-[(1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-carbonyl)amino]butanoyl}amino)-1-methyl-1H-imidazole-2-carbonyl]amino}-1-methyl-1H-pyrrole-2-carbonyl)amino]-1-methyl-1H-pyrrole-2-carbonyl}amino)-1-methyl-1H-pyrrole-2-carbonyl]amino}propyl)(methyl)amino]propyl}carbamoyl)benzoic acid, ACETATE ION, non-template DNA, ... 著者 Oh, J, Dervan, P.B, Wang, D. 登録日 2021-07-20 公開日 2022-01-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder. Proc.Natl.Acad.Sci.USA, 119, 2022
1IW7	Crystal structure of the RNA polymerase holoenzyme from Thermus thermophilus at 2.6A resolution 分子名称: LEAD (II) ION, MAGNESIUM ION, RNA polymerase alpha subunit, ... 著者 RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2002-04-22 公開日 2002-06-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolution NATURE, 417, 2002
2JLG	STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA-DEPENDENT RNA POLYMERASE 分子名称: 5'-D(*DT DT DT DC DCP)-3', GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... 著者 Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. 登録日 2008-09-09 公開日 2008-11-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase. Nucleic Acids Res., 36, 2008
3NFG	Crystal structure of Dimerization module of RNA polymerase I subcomplex A49/A34.5 分子名称: DNA-directed RNA polymerase I subunit RPA34, DNA-directed RNA polymerase I subunit RPA49 著者 Geiger, S.R. 登録日 2010-06-10 公開日 2010-09-08 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex. Mol.Cell, 39, 2010
3NFI	Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DNA-directed RNA polymerase I subunit RPA49 著者 Geiger, S.R, Lorenzen, K, Schreieck, A, Hanecker, P, Kostrewa, D, Heck, A.J.R, Cramer, P. 登録日 2010-06-10 公開日 2010-09-08 最終更新日 2015-03-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex. Mol.Cell, 39, 2010
3NFH	Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4) 分子名称: DNA-directed RNA polymerase I subunit RPA49 著者 Geiger, S.R, Lorenzen, K, Schreieck, A, Hanecker, P, Kostrewa, D, Heck, A.J.R, Cramer, P. 登録日 2010-06-10 公開日 2010-09-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex. Mol.Cell, 39, 2010
3CJ3	Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments 分子名称: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase 著者 Kissinger, c. 登録日 2008-03-12 公開日 2008-04-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
3CJ2	Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments 分子名称: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase 著者 Kissinger, c. 登録日 2008-03-12 公開日 2008-04-15 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
4NC8	N-terminal domain of delta-subunit of RNA polymerase complexed with nickel ions 分子名称: DNA-directed RNA polymerase subunit delta, NICKEL (II) ION 著者 Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M. 登録日 2013-10-24 公開日 2014-07-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase. J.Struct.Biol., 187, 2014
4NC7	N-terminal domain of delta-subunit of RNA polymerase complexed with I3C and nickel ions 分子名称: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, DNA-directed RNA polymerase subunit delta, NICKEL (II) ION 著者 Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M. 登録日 2013-10-24 公開日 2014-07-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase. J.Struct.Biol., 187, 2014
4FLB	CID of human RPRD2 分子名称: PRASEODYMIUM ION, Regulation of nuclear pre-mRNA domain-containing protein 2, SULFATE ION, ... 著者 Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) 登録日 2012-06-14 公開日 2012-08-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
4FLA	Crystal structure of human RPRD1B, carboxy-terminal domain 分子名称: Regulation of nuclear pre-mRNA domain-containing protein 1B, UNKNOWN ATOM OR ION 著者 Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) 登録日 2012-06-14 公開日 2012-08-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
8BYQ	RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W) 分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... 著者 Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. 登録日 2022-12-14 公開日 2023-05-03 最終更新日 2023-06-14 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Mol.Cell, 83, 2023
7NKX	RNA polymerase II-Spt4/5-nucleosome-Chd1 structure 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin elongation factor SPT4, ... 著者 Farnung, L, Ochmann, M, Engeholm, M, Cramer, P. 登録日 2021-02-19 公開日 2021-08-25 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis of nucleosome transcription mediated by Chd1 and FACT. Nat.Struct.Mol.Biol., 28, 2021
8BVW	RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W) 分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... 著者 Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. 登録日 2022-12-20 公開日 2023-05-03 最終更新日 2023-06-14 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Mol.Cell, 83, 2023
8BZ1	RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W) 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. 登録日 2022-12-14 公開日 2023-05-03 最終更新日 2023-06-14 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Mol.Cell, 83, 2023
2E2J	RNA polymerase II elongation complex in 5 mM Mg+2 with GMPCPP 分子名称: 27-MER DNA template strand, 5'-D(P*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*A)-3', 5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*G)-3', ... 著者 Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. 登録日 2006-11-14 公開日 2006-12-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis Cell(Cambridge,Mass.), 127, 2006

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