Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2FE6
DownloadVisualize
BU of 2fe6 by Molmil
P450CAM from Pseudomonas putida reconstituted with manganic protoporphyrin IX
分子名称: Cytochrome P450-cam, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING MN
著者von Koenig, K, Makris, T.M, Sligar, S.G, Schlichting, I.
登録日2005-12-15
公開日2006-03-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The status of high-valent metal oxo complexes in the P450 cytochromes.
J.Inorg.Biochem., 100, 2006
2FDY
DownloadVisualize
BU of 2fdy by Molmil
Microsomal P450 2A6 with the inhibitor Adrithiol bound
分子名称: 4,4'-DIPYRIDYL DISULFIDE, Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Yano, J.K, Stout, C.D, Johnson, E.F.
登録日2005-12-14
公開日2006-11-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Synthetic Inhibitors of Cytochrome P-450 2A6: Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization.
J.Med.Chem., 49, 2006
6RQ8
DownloadVisualize
BU of 6rq8 by Molmil
CYP121 in complex with 3-iodo dicyclotyrosine
分子名称: (3~{S},6~{S})-3-[(4-hydroxyphenyl)methyl]-6-[(3-iodanyl-4-oxidanyl-phenyl)methyl]piperazine-2,5-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Mycocyclosin synthase, ...
著者Poddar, H, Levy, C.
登録日2019-05-15
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Structure-Activity Relationships of cyclo (l-Tyrosyl-l-tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to High-Spin Adduct.
J.Med.Chem., 62, 2019
6RQ0
DownloadVisualize
BU of 6rq0 by Molmil
CYP121 in complex with 3-methyl dicyclotyrosine
分子名称: (3~{S},6~{S})-3-[(4-hydroxyphenyl)methyl]-6-[(3-methyl-4-oxidanyl-phenyl)methyl]piperazine-2,5-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Mycocyclosin synthase, ...
著者Poddar, H, Levy, C.
登録日2019-05-15
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure-Activity Relationships of cyclo (l-Tyrosyl-l-tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to High-Spin Adduct.
J.Med.Chem., 62, 2019
6RQD
DownloadVisualize
BU of 6rqd by Molmil
CYP121 in complex with 3-chloro dicyclotyrosine
分子名称: (3~{S},6~{S})-3-[(3-chloranyl-4-oxidanyl-phenyl)methyl]-6-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Poddar, H, Levy, C.
登録日2019-05-15
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.499 Å)
主引用文献Structure-Activity Relationships of cyclo (l-Tyrosyl-l-tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to High-Spin Adduct.
J.Med.Chem., 62, 2019
6RO8
DownloadVisualize
BU of 6ro8 by Molmil
The crystal structure of Acinetobacter radioresistens CYP116B5 heme domain
分子名称: Cytochrome P450 RhF, HISTIDINE, PROTOPORPHYRIN IX CONTAINING FE
著者Ciaramella, A, Catucci, G, Gilardi, G, Di Nardo, G.
登録日2019-05-10
公開日2019-08-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of bacterial CYP116B5 heme domain: New insights on class VII P450s structural flexibility and peroxygenase activity.
Int.J.Biol.Macromol., 140, 2019
6RQ1
DownloadVisualize
BU of 6rq1 by Molmil
CYP121 in complex with 2-methyl dicyclotyrosine
分子名称: (3~{S},6~{S})-3-[(4-hydroxyphenyl)methyl]-6-[(2-methyl-4-oxidanyl-phenyl)methyl]piperazine-2,5-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Mycocyclosin synthase, ...
著者Poddar, H, Levy, C.
登録日2019-05-15
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structure-Activity Relationships of cyclo (l-Tyrosyl-l-tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to High-Spin Adduct.
J.Med.Chem., 62, 2019
6RQB
DownloadVisualize
BU of 6rqb by Molmil
CYP121 in complex with 3-bromo dicyclotyrosine
分子名称: 3-bromo dicyclotyrosine, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Poddar, H, Levy, C.
登録日2019-05-15
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.459 Å)
主引用文献Structure-Activity Relationships of cyclo (l-Tyrosyl-l-tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to High-Spin Adduct.
J.Med.Chem., 62, 2019
6RQ9
DownloadVisualize
BU of 6rq9 by Molmil
CYP121 in complex with O-methyl dicyclotyrosine
分子名称: (3~{S},6~{S})-3-[(4-hydroxyphenyl)methyl]-6-[(4-methoxyphenyl)methyl]piperazine-2,5-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Mycocyclosin synthase, ...
著者Poddar, H, Levy, C.
登録日2019-05-15
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-Activity Relationships of cyclo (l-Tyrosyl-l-tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to High-Spin Adduct.
J.Med.Chem., 62, 2019
3VOO
DownloadVisualize
BU of 3voo by Molmil
Cytochrome P450SP alpha (CYP152B1) mutant A245E
分子名称: Fatty acid alpha-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE
著者Fujishiro, T, Shoji, O, Sugimoto, H, Shiro, Y, Watanabe, Y.
登録日2012-01-31
公開日2013-02-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献A substrate-binding-state mimic of H2O2-dependent cytochrome P450 produced by one-point mutagenesis and peroxygenation of non-native substrates
Catalysis Science And Technology, 6, 2016
3VNO
DownloadVisualize
BU of 3vno by Molmil
Cytochrome P450SP alpha (CYP152B1) mutant R241E
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Fatty acid alpha-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE
著者Fujishiro, T, Shoji, O, Sugimoto, H, Shiro, Y, Watanabe, Y.
登録日2012-01-17
公開日2013-02-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献A substrate-binding-state mimic of H2O2-dependent cytochrome P450 produced by one-point mutagenesis and peroxygenation of non-native substrates
Catalysis Science And Technology, 6, 2016
3VRM
DownloadVisualize
BU of 3vrm by Molmil
Structure of cytochrome P450 Vdh mutant T107A with bound vitamin D3
分子名称: (1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLI DENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL, PROTOPORPHYRIN IX CONTAINING FE, Vitamin D(3) 25-hydroxylase
著者Nishioka, T, Yasutake, Y, Tamura, T.
登録日2012-04-12
公開日2013-04-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献A single mutation at the ferredoxin binding site of p450 vdh enables efficient biocatalytic production of 25-hydroxyvitamin d3.
Chembiochem, 14, 2013
6RQ6
DownloadVisualize
BU of 6rq6 by Molmil
CYP121 in complex with 3-fluoro dicyclotyrosine
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-fluoro dicyclotyrosine, Mycocyclosin synthase, ...
著者Poddar, H, Levy, C.
登録日2019-05-15
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structure-Activity Relationships of cyclo (l-Tyrosyl-l-tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to High-Spin Adduct.
J.Med.Chem., 62, 2019
7CB9
DownloadVisualize
BU of 7cb9 by Molmil
CYP76AH1/miltiradiene from Salvia miltiorrhiza
分子名称: Ferruginol synthase, Miltiradiene, PROTOPORPHYRIN IX CONTAINING FE
著者Chang, Z, Chao, S, Mingyue, G.
登録日2020-06-11
公開日2021-06-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献CYP76AH1 from Salvia miltiorrhiza
To Be Published
7CL9
DownloadVisualize
BU of 7cl9 by Molmil
Androstenedione-bound structure of CYP154C2 from Streptomyces avermitilis in an open conformation
分子名称: 4-ANDROSTENE-3-17-DIONE, Cytochrome P450 hydroxylase, DI(HYDROXYETHYL)ETHER, ...
著者Xu, L.H, Fushinobu, S.
登録日2020-07-20
公開日2021-07-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Androstenedione-bound structure of CYP154C2 from Streptomyces avermitilis in an open conformation
To Be Published
7CL7
DownloadVisualize
BU of 7cl7 by Molmil
Substrate-free structure of CYP154C2 from Streptomyces avermitilis in an open conformation
分子名称: Cytochrome P450 hydroxylase, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE
著者Xu, L.H, Fushinobu, S.
登録日2020-07-20
公開日2021-07-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Substrate-free structure of CYP154C2 in an open conformation
To Be Published
7CL8
DownloadVisualize
BU of 7cl8 by Molmil
Testosterone-bound structure of CYP154C2 from Streptomyces avermitilis in an closed conformation
分子名称: Cytochrome P450 hydroxylase, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Xu, L.H, Fushinobu, S.
登録日2020-07-20
公開日2021-07-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Improved 2 alpha-Hydroxylation Efficiency of Steroids by CYP154C2 Using Structure-Guided Rational Design.
Appl.Environ.Microbiol., 89, 2023
1CPT
DownloadVisualize
BU of 1cpt by Molmil
CRYSTAL STRUCTURE AND REFINEMENT OF CYTOCHROME P450-TERP AT 2.3 ANGSTROMS RESOLUTION
分子名称: CYTOCHROME P450-TERP, PROTOPORPHYRIN IX CONTAINING FE
著者Hasemann, C.A, Ravichandran, K.G, Peterson, J.A, Deisenhofer, J.
登録日1993-11-23
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure and refinement of cytochrome P450terp at 2.3 A resolution.
J.Mol.Biol., 236, 1994
7CVR
DownloadVisualize
BU of 7cvr by Molmil
Structure of the CYP102A1 Haem Domain with N-Carboxybenzyl-L-Prolyl-L-Phenylalanine in complex with (S)-1-Tetralylamine
分子名称: (1~{S})-1,2,3,4-tetrahydronaphthalen-1-amine, (2S)-3-phenyl-2-[[(2S)-1-phenylmethoxycarbonylpyrrolidin-2-yl]carbonylamino]propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, ...
著者Stanfield, J.K, Sugimoto, H, Shoji, O.
登録日2020-08-26
公開日2021-09-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of the CYP102A1 Haem Domain with N-Carboxybenzyl-L-Prolyl-L-Phenylalanine in complex with (S)-1-Tetralylamine at 1.60 Angstrom Resolution
To Be Published
7COO
DownloadVisualize
BU of 7coo by Molmil
Structure of the CYP102A1 Haem Domain with N-Carboxybenzyl-L-Prolyl-L-Phenylalanine in complex with Cyclohexylamine
分子名称: (2S)-3-phenyl-2-[[(2S)-1-phenylmethoxycarbonylpyrrolidin-2-yl]carbonylamino]propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, CYCLOHEXYLAMMONIUM ION, ...
著者Stanfield, J.K, Sugimoto, H, Shoji, O.
登録日2020-08-04
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structure of the CYP102A1 Haem Domain with N-Carboxybenzyl-L-Prolyl-L-Phenylalanine in complex with Cyclohexylamine at 1.49 Angstrom Resolution
To Be Published
7CON
DownloadVisualize
BU of 7con by Molmil
Structure of the CYP102A1 Haem Domain with N-{2-[4-(Trifluoromethoxy)phenoxy]}acetoyl-L-Phenylalanine in complex with n-Propylamine
分子名称: (2S)-3-phenyl-2-[2-[4-(trifluoromethyloxy)phenoxy]ethanoylamino]propanoic acid, 3-AMINOPROPANE, Bifunctional cytochrome P450/NADPH--P450 reductase, ...
著者Stanfield, J.K, Sugimoto, H, Shoji, O.
登録日2020-08-04
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Structure of the CYP102A1 Haem Domain with N-{2-[4-(trifluoromethoxy)phenoxy]}acetoyl-L-phenylalanine in complex with n-propylamine at 1.46 Angstrom Resolution
To Be Published
7CKN
DownloadVisualize
BU of 7ckn by Molmil
Structure of the CYP102A1 Haem Domain with N-{2-[4-(Trifluoromethoxy)phenoxy]}acetoyl-L-Phenylalanine in complex with Isopropylamine
分子名称: (2S)-3-phenyl-2-[2-[4-(trifluoromethyloxy)phenoxy]ethanoylamino]propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, GLYCEROL, ...
著者Stanfield, J.K, Sugimoto, H, Shoji, O.
登録日2020-07-17
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of the CYP102A1 Haem Domain with N-{2-[4-(Trifluoromethoxy)phenoxy]}acetoyl-L-Phenylalanine in complex with Isopropylamine at 1.55 Angstrom Resolution
To Be Published
7CX6
DownloadVisualize
BU of 7cx6 by Molmil
Structure of the CYP102A1 Haem Domain with N-(5-Cyclohexyl)valeroyl-L-Phenylalanine in complex with (R)-(+)-1-Phenylethylamine
分子名称: (1R)-1-phenylethanamine, (2~{S})-2-(5-cyclohexylpentanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, ...
著者Stanfield, J.K, Sugimoto, H, Shoji, O.
登録日2020-09-01
公開日2021-09-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structure of the CYP102A1 Haem Domain with N-(5-Cyclohexyl)valeroyl-L-Phenylalanine in complex with (R)-(+)-1-Phenylethylamine at 1.69 Angstrom Resolution
To Be Published
7CX8
DownloadVisualize
BU of 7cx8 by Molmil
Structure of the CYP102A1 Haem Domain with N-(5-Cyclohexyl)valeroyl-L-Phenylalanine in complex with (R)-1-Tetralylamine
分子名称: (1R)-1,2,3,4-tetrahydronaphthalen-1-amine, (1~{S})-1,2,3,4-tetrahydronaphthalen-1-amine, (2~{S})-2-(5-cyclohexylpentanoylamino)-3-phenyl-propanoic acid, ...
著者Stanfield, J.K, Sugimoto, H, Shoji, O.
登録日2020-09-01
公開日2021-09-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the CYP102A1 Haem Domain with N-(5-Cyclohexyl)valeroyl-L-Phenylalanine in complex with (R)-1-Tetralylamine at 1.70 Angstrom Resolution
To Be Published
7CP8
DownloadVisualize
BU of 7cp8 by Molmil
Structure of the CYP102A1 Haem Domain with N-(5-Cyclohexyl)valeroyl-L-Phenylalanine in complex with (R)-1-Indanylamine
分子名称: (2~{S})-2-(5-cyclohexylpentanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, GLYCEROL, ...
著者Stanfield, J.K, Sugimoto, H, Shoji, O.
登録日2020-08-06
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structure of the CYP102A1 Haem Domain with N-(5-Cyclohexyl)valeroyl-L-Phenylalanine in complex with (R)-1-Indanylamine at 1.68 Angstrom Resolution
To Be Published

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon