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6ZY9
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Cryo-EM structure of MlaFEDB in complex with AMP-PNP
分子名称: ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, MAGNESIUM ION, ...
著者Dong, C.J, Dong, H.H.
登録日2020-07-30
公開日2020-11-25
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into outer membrane asymmetry maintenance in Gram-negative bacteria by MlaFEDB.
Nat.Struct.Mol.Biol., 28, 2021
7AHD
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BU of 7ahd by Molmil
OpuA (E190Q) occluded
分子名称: ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B.
登録日2020-09-24
公開日2020-11-25
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7AHH
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OpuA inhibited inward-facing, SBD docked
分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component, ...
著者Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B.
登録日2020-09-24
公開日2020-11-25
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7AHC
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BU of 7ahc by Molmil
OpuA apo inward-facing
分子名称: ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component
著者Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B.
登録日2020-09-24
公開日2020-11-25
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
7AHE
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OpuA inhibited inward facing
分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ABC transporter permease subunit, ABC-type proline/glycine betaine transport system ATPase component
著者Sikkema, H.R, Rheinberger, J, Paulino, C, Poolman, B.
登録日2020-09-24
公開日2020-11-25
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
Sci Adv, 6, 2020
6YIR
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BU of 6yir by Molmil
Crystal structure of Bacillus subtilis MsmX ATPase
分子名称: Oligosaccharides import ATP-binding protein MsmX, SULFATE ION, TRIETHYLENE GLYCOL
著者Leisico, F, Santos-Silva, T, Romao, M.J.
登録日2020-04-01
公開日2020-11-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Multitask ATPases (NBDs) of bacterial ABC importers type I and their interspecies exchangeability.
Sci Rep, 10, 2020
6ZU9
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BU of 6zu9 by Molmil
Structure of a yeast ABCE1-bound 48S initiation complex
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-07-22
公開日2020-10-28
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
7D7N
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BU of 7d7n by Molmil
Cryo-EM structure of human ABCB6 transporter
分子名称: ATP-binding cassette sub-family B member 6, mitochondrial
著者Wang, C, Cao, C, Wang, N, Wang, X, Zhang, X.C.
登録日2020-10-05
公開日2020-10-21
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Cryo-electron microscopy structure of human ABCB6 transporter.
Protein Sci., 29, 2020
7D7R
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Cryo-EM structure of the core domain of human ABCB6 transporter
分子名称: ATP-binding cassette sub-family B member 6, mitochondrial
著者Wang, C, Cao, C, Wang, N, Wang, X, Zhang, X.C.
登録日2020-10-05
公開日2020-10-21
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-electron microscopy structure of human ABCB6 transporter.
Protein Sci., 29, 2020
7A69
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BU of 7a69 by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and vincristine
分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-21
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6C
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BU of 7a6c by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and elacridar
分子名称: CHOLESTEROL, If kappa light chain, MRK16 Fab-fragment heavy chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-14
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6F
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BU of 7a6f by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar
分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-14
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A65
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BU of 7a65 by Molmil
Nanodisc reconstituted, drug-free human ABCB1 in complex with MRK16 Fab
分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-14
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A6E
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BU of 7a6e by Molmil
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and tariquidar
分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-14
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
7A09
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BU of 7a09 by Molmil
Structure of a human ABCE1-bound 43S pre-initiation complex - State III
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-08-07
公開日2020-10-14
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
7A1G
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BU of 7a1g by Molmil
Structure of a crosslinked yeast ABCE1-bound 43S pre-initiation complex
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Mackens-Kiani, T, Kratzat, H, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-08-13
公開日2020-10-14
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
6XJH
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BU of 6xjh by Molmil
PmtCD ABC exporter without the basket domain at C2 symmetry
分子名称: ABC transporter ATP-binding protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Zeytuni, N, Strynadka, N.J.C, Hu, J, Worrall, L.J, Chou, H, Yu, Z.
登録日2020-06-23
公開日2020-10-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins
Sci Adv, 6, 2020
6XJI
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BU of 6xji by Molmil
PmtCD ABC exporter at C1 symmetry
分子名称: ABC transporter ATP-binding protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Zeytuni, N, Strynadka, N.J.C, Hu, J, Worrall, L.J, Chou, H, Yu, Z.
登録日2020-06-23
公開日2020-10-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins
Sci Adv, 6, 2020
6ZCE
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BU of 6zce by Molmil
Structure of a yeast ABCE1-bound 43S pre-initiation complex
分子名称: 18S ribosomal RNA (1719-MER), 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-06-10
公開日2020-10-07
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
6ZVJ
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BU of 6zvj by Molmil
Structure of a human ABCE1-bound 43S pre-initiation complex - State II
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-07-24
公開日2020-10-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
6UK1
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BU of 6uk1 by Molmil
Crystal structure of nucleotide-binding domain 2 (NBD2) of the human Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Wang, C, Vorobiev, S.M, Vernon, R.M, Khazanov, N, Senderowitz, H, Forman-Kay, J.D, Hunt, J.F.
登録日2019-10-03
公開日2020-10-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.693 Å)
主引用文献A thermodynamically stabilized form of the second nucleotide binding domain from human CFTR shows a catalytically inactive conformation
To Be Published
7CGE
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BU of 7cge by Molmil
The overall structure of nucleotide free MlaFEDB complex
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ...
著者Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y.
登録日2020-07-01
公開日2020-09-09
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural mechanism of phospholipids translocation by MlaFEDB complex.
Cell Res., 30, 2020
7CGN
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BU of 7cgn by Molmil
The overall structure of the MlaFEDB complex in ATP-bound EQtall conformation (Mutation of E170Q on MlaF)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ...
著者Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y.
登録日2020-07-01
公開日2020-09-09
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural mechanism of phospholipids translocation by MlaFEDB complex.
Cell Res., 30, 2020
7CH0
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BU of 7ch0 by Molmil
The overall structure of the MlaFEDB complex in ATP-bound EQclose conformation (Mutation of E170Q on MlaF)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ...
著者Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y.
登録日2020-07-03
公開日2020-09-09
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural mechanism of phospholipids translocation by MlaFEDB complex.
Cell Res., 30, 2020
6Z4W
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BU of 6z4w by Molmil
FtsE structure from Streptococcus pneumoniae in complex with ADP (space group P 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE
著者Alcorlo, M, Straume, D, Hermoso, J.A, Havarstein, L.S.
登録日2020-05-26
公開日2020-09-02
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Structural Characterization of the Essential Cell Division Protein FtsE and Its Interaction with FtsX in Streptococcus pneumoniae.
Mbio, 11, 2020

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件を2024-05-29に公開中

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