7MEW
| E. coli MsbA in complex with G247 | 分子名称: | (2E)-3-{1-cyclopropyl-7-[(1S)-1-(3,6-dichloro-2-fluorophenyl)ethoxy]naphthalen-2-yl}prop-2-enoic acid, ATP-dependent lipid A-core flippase | 著者 | Thelot, F, Liao, M. | 登録日 | 2021-04-08 | 公開日 | 2021-10-06 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Distinct allosteric mechanisms of first-generation MsbA inhibitors. Science, 374, 2021
|
|
7MJP
| Vascular KATP channel: Kir6.1 SUR2B propeller-like conformation 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Sung, M.W, Shyng, S.L. | 登録日 | 2021-04-20 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7MJO
| Vascular KATP channel: Kir6.1 SUR2B quatrefoil-like conformation 1 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ... | 著者 | Sung, M.W, Shyng, S.L. | 登録日 | 2021-04-20 | 公開日 | 2021-10-13 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7MJQ
| Vascular KATP channel: Kir6.1 SUR2B quatrefoil-like conformation 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ATP-sensitive inward rectifier potassium channel 8, ... | 著者 | Sung, M.W, Shyng, S.L. | 登録日 | 2021-04-20 | 公開日 | 2021-10-13 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7MSZ
| |
7MU0
| MtbEttA in the ADP bound state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Energy-dependent translational throttle protein EttA, MAGNESIUM ION | 著者 | Cui, Z, Zhang, J. | 登録日 | 2021-05-14 | 公開日 | 2022-02-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
|
|
7MSM
| |
7MSH
| Mtb 70SIC in complex with MtbEttA at Pre_R1 state | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Cui, Z, Zhang, J. | 登録日 | 2021-05-11 | 公開日 | 2022-02-02 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
|
|
7MSC
| Mtb 70SIC in complex with MtbEttA at Pre_R0 state | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Cui, Z, Zhang, J. | 登録日 | 2021-05-11 | 公開日 | 2022-02-02 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
|
|
7M68
| |
7M69
| |
7MIT
| Vascular KATP channel: Kir6.1 SUR2B propeller-like conformation 1 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ... | 著者 | Sung, M.W, Shyng, S.L. | 登録日 | 2021-04-17 | 公開日 | 2021-10-13 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7NEZ
| Structure of topotecan-bound ABCG2 | 分子名称: | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, ... | 著者 | Kowal, J, Locher, K, Ni, D, Stahlberg, H. | 登録日 | 2021-02-05 | 公開日 | 2021-04-21 | 最終更新日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2. J.Mol.Biol., 433, 2021
|
|
7NFD
| Structure of mitoxantrone-bound ABCG2 | 分子名称: | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, ... | 著者 | Kowal, J, Locher, K, Ni, D, Stahlberg, H. | 登録日 | 2021-02-06 | 公開日 | 2021-04-21 | 最終更新日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | 主引用文献 | Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2. J.Mol.Biol., 433, 2021
|
|
7NEQ
| Structure of tariquidar-bound ABCG2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... | 著者 | Kowal, J, Locher, K. | 登録日 | 2021-02-04 | 公開日 | 2021-04-21 | 最終更新日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2. J.Mol.Biol., 433, 2021
|
|
7NHN
| VgaL, an antibiotic resistance ABCF, in complex with 70S ribosome from Listeria monocytogenes | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Crowe-McAuliffe, C, Turnbull, K.J, Hauryliuk, V, Wilson, D.N. | 登録日 | 2021-02-10 | 公開日 | 2021-05-05 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens. Nat Commun, 12, 2021
|
|
7NHL
| VgaA-LC, an antibiotic resistance ABCF, in complex with 70S ribosome from Staphylococcus aureus | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Crowe-McAuliffe, C, Murina, V, Hauryliuk, V, Wilson, D.N. | 登録日 | 2021-02-10 | 公開日 | 2021-05-05 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens. Nat Commun, 12, 2021
|
|
8CUB
| |
7BG4
| Multidrug resistance transporter BmrA mutant E504A bound with ATP, Mg, and Rhodamine 6G solved by Cryo-EM | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Lipid A export ATP-binding/permease protein MsbA, MAGNESIUM ION, ... | 著者 | Wiseman, B, Chaptal, V, Zampieri, V, Magnard, S, Hogbom, M, Falson, P. | 登録日 | 2021-01-05 | 公開日 | 2022-01-12 | 最終更新日 | 2022-02-02 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter. Sci Adv, 8, 2022
|
|
7BCW
| Structure of MsbA in Salipro with ADP vanadate | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-DIPHOSPHATE, ATP-dependent lipid A-core flippase, ... | 著者 | Traore, D.A.K, Tidow, H. | 登録日 | 2020-12-21 | 公開日 | 2022-01-12 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structure of MsbA in saposin-lipid nanoparticles (Salipro) provides insights into nucleotide coordination. Febs J., 289, 2022
|
|
8CAS
| Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial) | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2023-01-24 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
|
|
8CAH
| Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2023-01-24 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
|
|
7CGE
| The overall structure of nucleotide free MlaFEDB complex | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ... | 著者 | Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y. | 登録日 | 2020-07-01 | 公開日 | 2020-09-09 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural mechanism of phospholipids translocation by MlaFEDB complex. Cell Res., 30, 2020
|
|
7CGN
| The overall structure of the MlaFEDB complex in ATP-bound EQtall conformation (Mutation of E170Q on MlaF) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ... | 著者 | Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y. | 登録日 | 2020-07-01 | 公開日 | 2020-09-09 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural mechanism of phospholipids translocation by MlaFEDB complex. Cell Res., 30, 2020
|
|
8CE1
| Cytochrome c maturation complex CcmABCD | 分子名称: | Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, Heme exporter protein C, ... | 著者 | Ilcu, L, Zhang, L, Einsle, O. | 登録日 | 2023-02-01 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation. Nat Commun, 14, 2023
|
|