PDB: 215264 件ウェブページステータス検索Chemie searchBIRD

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3DU8	Crystal structure of GSK-3 beta in complex with NMS-869553A 分子名称: (7S)-2-(2-aminopyrimidin-4-yl)-7-(2-fluoroethyl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one, Glycogen synthase kinase-3 beta 著者 Bossi, R.T. 登録日 2008-07-17 公開日 2009-03-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 First Cdc7 kinase inhibitors: pyrrolopyridinones as potent and orally active antitumor agents. 2. Lead discovery. J.Med.Chem., 52, 2009
149D	SOLUTION STRUCTURE OF A PYRIMIDINE(DOT)PURINE(DOT) PYRIMIDINE DNA TRIPLEX CONTAINING T(DOT)AT, C+(DOT)GC AND G(DOT)TA TRIPLES 分子名称: 5'-D(*CP*CP*TP*AP*TP*TP*C)-3', 5'-D(*CP*TP*TP*GP*TP*CP*C)-3', 5'-D(*GP*AP*AP*TP*AP*GP*G)-3' 著者 Radhakrishnan, I, Patel, D.J. 登録日 1993-11-15 公開日 1994-04-30 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of a pyrimidine.purine.pyrimidine DNA triplex containing T.AT, C+.GC and G.TA triples. Structure, 2, 1994
4JLV	Crystal structure of the chimerical protein CapA1B1 in complex with ADP-Mg 分子名称: ADENOSINE-5'-DIPHOSPHATE, C-terminal fragment of Membrane protein CapA1, Putative uncharacterized protein capB1, ... 著者 Gruszczyk, J, Olivares-Illana, V, Nourikyan, J, Fleurie, A, Bechet, E, Aumont-Nicaise, M, Gueguen-Chaignon, V, Morera, S, Grangeasse, C, Nessler, S. 登録日 2013-03-13 公開日 2014-02-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Comparative analysis of the Tyr-kinases CapB1 and CapB2 fused to their cognate modulators CapA1 and CapA2 from Staphylococcus aureus Plos One, 8, 2013
4JJ0	Crystal structure of MamP 分子名称: GLYCEROL, HEME C, MamP 著者 Siponen, M, Pignol, D, Arnoux, P. 登録日 2013-03-07 公開日 2013-10-09 最終更新日 2013-11-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural insight into magnetochrome-mediated magnetite biomineralization. Nature, 502, 2013
2KOD	A high-resolution NMR structure of the dimeric C-terminal domain of HIV-1 CA 分子名称: HIV-1 CA C-terminal domain 著者 Byeon, I.-J.L, Jung, J, Ahn, J, concel, J, Gronenborn, A.M. 登録日 2009-09-18 公開日 2009-11-24 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function. Cell(Cambridge,Mass.), 139, 2009
4BMH	Crystal structure of SsHAT 分子名称: ACETYLTRANSFERASE, CHLORIDE ION 著者 He, Y, Turkenburg, J.P, Davies, G.J. 登録日 2013-05-08 公開日 2014-01-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Three-Dimensional Structure of a Streptomyces Sviceus Gnat Acetyltransferase with Similarity to the C-Terminal Domain of the Human Gh84 O-Glcnacase Acta Crystallogr.,Sect.D, 70, 2014
5QXM	PanDDA analysis group deposition -- Crystal Structure of ATAD2 in complex with DF789 分子名称: 1,2-ETHANEDIOL, ATPase family AAA domain-containing protein 2, SULFATE ION, ... 著者 Snee, M, Talon, R, Fowley, D, Collins, P, Nelson, A, Arrowsmith, C.H, Bountra, C, Edwards, A, Von-Delft, F. 登録日 2020-02-11 公開日 2020-04-08 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening To Be Published
5QXL	PanDDA analysis group deposition -- Crystal Structure of ATAD2 in complex with DF776 分子名称: 1,2-ETHANEDIOL, ATPase family AAA domain-containing protein 2, SULFATE ION, ... 著者 Snee, M, Talon, R, Fowley, D, Collins, P, Nelson, A, Arrowsmith, C.H, Bountra, C, Edwards, A, Von-Delft, F. 登録日 2020-02-11 公開日 2020-04-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening To Be Published
5QXN	PanDDA analysis group deposition -- Crystal Structure of ATAD2 in complex with DF826 分子名称: (3aR,8S,9aS)-2-[(trifluoromethyl)sulfonyl]decahydro-3a,8-epoxypyrrolo[3,4-c]azocine, 1,2-ETHANEDIOL, ATPase family AAA domain-containing protein 2, ... 著者 Snee, M, Talon, R, Fowley, D, Collins, P, Nelson, A, Arrowsmith, C.H, Bountra, C, Edwards, A, Von-Delft, F. 登録日 2020-02-11 公開日 2020-04-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening To Be Published
1AN8	CRYSTAL STRUCTURE OF THE STREPTOCOCCAL SUPERANTIGEN SPE-C 分子名称: STREPTOCOCCAL PYROGENIC EXOTOXIN C 著者 Roussel, A, Baker, E.N. 登録日 1997-06-27 公開日 1998-04-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the streptococcal superantigen SPE-C: dimerization and zinc binding suggest a novel mode of interaction with MHC class II molecules. Nat.Struct.Biol., 4, 1997
3ZRM	Identification of 2-(4-pyridyl)thienopyridinones as GSK-3beta inhibitors 分子名称: 7-(4-HYDROXYPHENYL)-2-PYRIDIN-4-YL-5H-THIENO[3,2-C]PYRIDIN-4-ONE, GLYCEROL, GLYCOGEN SYNTHASE KINASE-3 BETA, ... 著者 Gentile, G, Bernasconi, G, Pozzan, A, Merlo, G, Marzorati, P, Bamborough, P, Bax, B, Bridges, A, Brough, C, Carter, P, Cutler, G, Neu, M, Takada, M. 登録日 2011-06-17 公開日 2011-06-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Identification of 2-(4-Pyridyl)Thienopyridinones as Gsk-3Beta Inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
3FRZ	Crystal Structure of HCV NS5B RNA polymerase in complex with PF868554 分子名称: (6R)-6-cyclopentyl-6-[2-(2,6-diethylpyridin-4-yl)ethyl]-3-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one, BETA-MERCAPTOETHANOL, N-[(benzyloxy)carbonyl]-L-alpha-glutamyl-N-[(1S)-4-oxo-4-phenyl-1-propylbut-2-en-1-yl]-L-phenylalaninamide, ... 著者 Parge, H.E. 登録日 2009-01-08 公開日 2009-03-10 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Discovery of (R)-6-cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a potent and orally available hepatitis C virus polymerase inhibitor. J.Med.Chem., 52, 2009
3ZRK	Identification of 2-(4-pyridyl)thienopyridinones as GSK-3beta inhibitors 分子名称: 2-(4-PYRIDINYL)FURO[3,2-C]PYRIDIN-4(5H)-ONE, GLYCEROL, GLYCOGEN SYNTHASE KINASE-3 BETA, ... 著者 Gentile, G, Bernasconi, G, Pozzan, A, Merlo, G, Marzorati, P, Bamborough, P, Bax, B, Bridges, A, Brough, C, Carter, P, Cutler, G, Neu, M, Takada, M. 登録日 2011-06-16 公開日 2011-06-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Identification of 2-(4-Pyridyl)Thienopyridinones as Gsk-3Beta Inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
3ZRL	Identification of 2-(4-pyridyl)thienopyridinones as GSK-3beta inhibitors 分子名称: 7-BROMO-2-PYRIDIN-4-YL-5H-THIENO[3,2-C]PYRIDIN-4-ONE, GLYCEROL, GLYCOGEN SYNTHASE KINASE-3 BETA, ... 著者 Gentile, G, Bernasconi, G, Pozzan, A, Merlo, G, Marzorati, P, Bamborough, P, Bax, B, Bridges, A, Brough, C, Carter, P, Cutler, G, Neu, M, Takada, M. 登録日 2011-06-17 公開日 2011-06-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Identification of 2-(4-Pyridyl)Thienopyridinones as Gsk-3Beta Inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
4K3I	Crystal Structure of the Quinol Form of Methylamine Dehydrogenase in Complex with the Diferrous Form of MauG, C2 Space Group 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Yukl, E.Y, Wilmot, C.M. 登録日 2013-04-10 公開日 2013-07-10 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of MauG in complex with quinol and quinone MADH. Acta Crystallogr.,Sect.F, 69, 2013
3Q0X	N-terminal coiled-coil dimer domain of C. reinhardtii SAS-6 homolog Bld12p 分子名称: Centriole protein 著者 Kitagawa, D, Vakonakis, I, Olieric, N, Hilbert, M, Keller, D, Olieric, V, Bortfeld, M, Erat, M.C, Flueckiger, I, Goenczy, P, Steinmetz, M.O. 登録日 2010-12-16 公開日 2011-02-09 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Structural basis of the 9-fold symmetry of centrioles. Cell(Cambridge,Mass.), 144, 2011
1B09	HUMAN C-REACTIVE PROTEIN COMPLEXED WITH PHOSPHOCHOLINE 分子名称: CALCIUM ION, PHOSPHOCHOLINE, PROTEIN (C-REACTIVE PROTEIN) 著者 Thompson, D, Pepys, M.B, Wood, S.P. 登録日 1998-11-18 公開日 1999-12-03 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The physiological structure of human C-reactive protein and its complex with phosphocholine. Structure Fold.Des., 7, 1999
3OZ5	S-Methyl Carbocyclic LNA 分子名称: DNA (5'-D(*GP*CP*GP*TP*AP*(UMX)P*AP*CP*GP*C)-3'), SPERMINE 著者 Seth, P.R, Allerson, C.A, Berdeja, A, Siwkowski, A, Pallan, P.S, Gaus, H, Prakash, T.P, Watt, A.T, Egli, M, Swayze, E.E. 登録日 2010-09-24 公開日 2010-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA. J.Am.Chem.Soc., 132, 2010
2GIY	Crystal Structure of the C-terminal domain of the HSV-1 gE ectodomain 分子名称: Glycoprotein E 著者 Sprague, E.R, Wang, C, Baker, D, Bjorkman, P.J. 登録日 2006-03-29 公開日 2006-05-30 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging. Plos Biol., 4, 2006
4DOY	Crystal structure of Dibenzothiophene desulfurization enzyme C 分子名称: Dibenzothiophene desulfurization enzyme C, GLYCEROL 著者 Liu, S, Zhang, C, Zhu, D, Gu, L. 登録日 2012-02-12 公開日 2013-02-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.789 Å) 主引用文献 Crystal structure of DszC from Rhodococcus sp. XP at 1.79 angstrom Proteins, 82, 2014
1AF9	TETANUS NEUROTOXIN C FRAGMENT 分子名称: TETANUS NEUROTOXIN 著者 Umland, T.C, Wingert, L, Swaminathan, S, Furey, W.F, Schmidt, J.J, Sax, M. 登録日 1997-03-24 公開日 1998-04-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of the receptor binding fragment HC of tetanus neurotoxin. Nat.Struct.Biol., 4, 1997
4CE1	Hsp90 N-terminal domain bound to macrolactam analogues of radicicol. 分子名称: 15-Chloro-16,18-dihydroxy-2-methyl-3,4,7,8,9,10,11,12-octahydrobenz[c][1]azacyclohexadecine-1,13(2H,14H)-dione, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 著者 Roe, S.M, Parry-Morris, S, Prodromou, C. 登録日 2013-11-08 公開日 2014-01-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Synthesis of Macrolactam Analogues of Radicicol and Their Binding to Heat Shock Protein Hsp90. Org.Biomol.Chem., 12, 2014
3GNW	HCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 4c 分子名称: (11S)-11-[4-(benzyloxy)-2-fluorophenyl]-3,3-dimethyl-10-[(6-methylpyridin-2-yl)carbonyl]-2,3,4,5,10,11-hexahydrothiopyrano[3,2-b][1,5]benzodiazepin-6-ol 1,1-dioxide, CHLORIDE ION, RNA-directed RNA polymerase 著者 Nyanguile, O, De Bondt, H. 登録日 2009-03-18 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase. J.Med.Chem., 52, 2009
4F83	Crystal structure of the receptor binding domain of botulinum neurotoxin mosaic serotype C/D with a tetraethylene glycol molecule bound on the Hcn sub-domain and a sulfate ion at the putative active site 分子名称: GLYCEROL, SULFATE ION, TETRAETHYLENE GLYCOL, ... 著者 Zhang, Y, Buchko, G.W, Gardberg, A, Edwards, T.E, Sankaran, B, Robinson, H, Varnum, S.M, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-05-16 公開日 2012-06-20 最終更新日 2013-06-12 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D. Biochimie, 95, 2013
3GM6	Structure of the Thioalkalivibrio nitratireducens cytochrome c nitrite reductase in complex with phosphate 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ... 著者 Trofimov, A.A, Polyakov, K.M, Boyko, K.M, Filimonenkov, A.A, Dorovatovsky, P.V, Tikhonova, T.V, Popov, V.O. 登録日 2009-03-13 公開日 2009-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of octaheme cytochrome c nitrite reductase from Thioalkalivibrio nitratireducens in a complex with phosphate Crystallography Reports, 55, 2010

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