4V7M
 
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1NI2
 | | Structure of the active FERM domain of Ezrin | | 分子名称: | Ezrin | | 著者 | Smith, W.J, Nassar, N, Bretscher, A.P, Cerione, R.A, Karplus, P.A. | | 登録日 | 2002-12-20 | | 公開日 | 2003-02-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the Active N-terminal Domain of Ezrin. CONFORMATIONAL AND MOBILITY CHANGES IDENTIFY KEYSTONE INTERACTIONS.
J.Biol.Chem., 278, 2003
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7OI8
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3A | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
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7OI6
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 1 | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
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7OI9
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3B | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
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7OIA
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3C | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
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7OI7
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 2 | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
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7OIB
 | | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3D | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-05-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
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2I1K
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2I1J
 | | Moesin from Spodoptera frugiperda at 2.1 angstroms resolution | | 分子名称: | CHLORIDE ION, GLYCEROL, Moesin, ... | | 著者 | Li, Q, Nance, M.R, Tesmer, J.J.G. | | 登録日 | 2006-08-14 | | 公開日 | 2006-12-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain.
J.Mol.Biol., 365, 2007
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1QBK
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1RRP
 | | STRUCTURE OF THE RAN-GPPNHP-RANBD1 COMPLEX | | 分子名称: | MAGNESIUM ION, NUCLEAR PORE COMPLEX PROTEIN NUP358, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Vetter, I.R, Nowak, C, Nishimoto, T, Kuhlmann, J, Wittinghofer, A. | | 登録日 | 1999-01-15 | | 公開日 | 1999-05-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport.
Nature, 398, 1999
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6K15
 | | RSC substrate-recruitment module | | 分子名称: | Chromatin structure-remodeling complex protein RSC3, Chromatin structure-remodeling complex protein RSC30, Chromatin structure-remodeling complex protein RSC58, ... | | 著者 | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | | 登録日 | 2019-05-09 | | 公開日 | 2019-11-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of the RSC complex bound to the nucleosome.
Science, 366, 2019
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1Q21
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6RCF
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-15]-OH | | 分子名称: | 2-[(3~{a}~{R},6~{R},8~{a}~{S})-1-[(3~{S},6~{R},8~{a}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-6-ethyl-8-oxidanylidene-3,3~{a},6,8~{a}-tetrahydro-2~{H}-pyrrolo[2,3-c]azepin-7-yl]ethanoic acid, NITRATE ION, Protein enabled homolog | | 著者 | Barone, M, Roske, Y. | | 登録日 | 2019-04-11 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6RCJ
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6RD2
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-1]-TEDEL-NH2 | | 分子名称: | (3~{S},7~{R},10~{R},13~{S})-4-[(3~{S},6~{R},8~{a}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-2-oxidanylidene-1,4-diazatricyclo[8.3.0.0^{3,7}]tridec-8-ene-13-carboxylic acid, GLYCEROL, NITRATE ION, ... | | 著者 | Barone, M, Roske, Y. | | 登録日 | 2019-04-12 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
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2L1A
 | | Solution NMR structure of the N-terminal GTPase-like domain of dictyostelium discoideum Fomin C | | 分子名称: | Formin-C | | 著者 | Dames, S.A, Schoenichen, A, Stephan, G, Geyer, M. | | 登録日 | 2010-07-27 | | 公開日 | 2011-08-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure, dynamics, lipid binding, and physiological relevance of the putative GTPase-binding domain of Dictyostelium formin C.
J.Biol.Chem., 286, 2011
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2BKH
 | | Myosin VI nucleotide-free (MDInsert2) crystal structure | | 分子名称: | CALCIUM ION, CALMODULIN, GLYCEROL, ... | | 著者 | Menetrey, J, Bahloul, A, Yengo, C, Wells, A, Morris, C, Sweeney, H.L, Houdusse, A. | | 登録日 | 2005-02-16 | | 公開日 | 2005-06-07 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Structure of the Myosin Vi Motor Reveals the Mechanism of Directionality Reversal
Nature, 435, 2005
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2CH5
 | | Crystal structure of human N-acetylglucosamine kinase in complex with N-acetylglucosamine | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | 著者 | Weihofen, W.A, Berger, M, Chen, H, Saenger, W, Hinderlich, S. | | 登録日 | 2006-03-13 | | 公開日 | 2006-09-18 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of Human N-Acetylglucosamine Kinase in Two Complexes with N-Acetylglucosamine and with Adp/Glucose: Insights Into Substrate Specificity and Regulation.
J.Mol.Biol., 364, 2006
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2V1W
 | | Crystal structure of human LIM protein RIL (PDLIM4) PDZ domain bound to the C-terminal peptide of human alpha-actinin-1 | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, PDZ AND LIM DOMAIN PROTEIN 4, ... | | 著者 | Soundararajan, M, Shrestha, L, Pike, A.C.W, Salah, E, Burgess-Brown, N, Elkins, J, Umeano, C, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Doyle, D. | | 登録日 | 2007-05-30 | | 公開日 | 2007-06-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Unusual Binding Interactions in Pdz Domain Crystal Structures Help Explain Binding Mechanisms.
Protein Sci., 19, 2010
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4N5C
 | | Crystal structure of Ypp1 | | 分子名称: | Cargo-transport protein YPP1 | | 著者 | Wu, X, Chi, R.J, Baskin, J.M, Lucast, L, Burd, C.G, De Camilli, P, Reinisch, K.M. | | 登録日 | 2013-10-09 | | 公開日 | 2014-01-22 | | 最終更新日 | 2014-03-19 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural insights into assembly and regulation of the plasma membrane phosphatidylinositol 4-kinase complex.
Dev.Cell, 28, 2014
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2CH6
 | | Crystal structure of human N-acetylglucosamine kinase in complex with ADP and glucose | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, N-ACETYL-D-GLUCOSAMINE KINASE, alpha-D-glucopyranose | | 著者 | Weihofen, W.A, Berger, M, Chen, H, Saenger, W, Hinderlich, S. | | 登録日 | 2006-03-13 | | 公開日 | 2006-09-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Structures of Human N-Acetylglucosamine Kinase in Two Complexes with N-Acetylglucosamine and with Adp/Glucose: Insights Into Substrate Specificity and Regulation.
J.Mol.Biol., 364, 2006
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2BAP
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3U8Z
 | | human merlin FERM domain | | 分子名称: | Merlin | | 著者 | Yogesha, S.D, Sharff, A.J, Giovannini, M, Bricogne, G, Izard, T. | | 登録日 | 2011-10-17 | | 公開日 | 2011-11-02 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Unfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressor.
Protein Sci., 20, 2011
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