PDB: 659 件ウェブページステータス検索Chemie searchBIRD

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5TYT	Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide 分子名称: Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera 著者 Spellmon, N, Holcomb, J, Niu, A, Choudhary, V, Sun, X, Brunzelle, J, Li, C, Yang, Z. 登録日 2016-11-21 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.398 Å) 主引用文献 Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF. Biochem. Biophys. Res. Commun., 485, 2017
5WQL	Structure of a PDZ-protease bound to a substrate-binding adaptor 分子名称: ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA, LEU-SER-ARG-SER, ... 著者 Su, M.Y, Chang, C.I. 登録日 2016-11-27 公開日 2017-11-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of adaptor-mediated protein degradation by the tail-specific PDZ-protease Prc Nat Commun, 8, 2017
5MV9	Structure of human Myosin 7a C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain 分子名称: ACETATE ION, Unconventional myosin-VIIa, cDNA FLJ51329, ... 著者 Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. 登録日 2017-01-16 公開日 2017-07-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
5MV8	Structure of human Myosin 7b C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain 分子名称: GLYCEROL, MAGNESIUM ION, Unconventional myosin-VIIb, ... 著者 Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. 登録日 2017-01-16 公開日 2017-07-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
5MZ7	Crystal Structure of the third PDZ domain from the synaptic protein PSD-95 with incorporated Azidohomoalanine 分子名称: Disks large homolog 4 著者 Kudlinzki, D, Lehner, F, Witt, K, Linhard, V.L, Silvers, R, Schwalbe, H. 登録日 2017-01-31 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Impact of Azidohomoalanine Incorporation on Protein Structure and Ligand Binding. Chembiochem, 18, 2017
5N7D	MAGI-1 complexed with a RSK1 peptide 分子名称: CALCIUM ION, GLYCEROL, Membrane-associated guanylate kinase, ... 著者 Gogl, G, Nyitray, L. 登録日 2017-02-20 公開日 2017-11-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Dynamic control of RSK complexes by phosphoswitch-based regulation. FEBS J., 285, 2018
5N7F	MAGI-1 complexed with a pRSK1 peptide 分子名称: CALCIUM ION, GLYCEROL, Membrane-associated guanylate kinase, ... 著者 Gogl, G, Nyitray, L. 登録日 2017-02-20 公開日 2017-11-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Dynamic control of RSK complexes by phosphoswitch-based regulation. FEBS J., 285, 2018
5N7G	MAGI-1 complexed with a synthetic pRSK1 peptide 分子名称: CALCIUM ION, GLYCEROL, Membrane-associated guanylate kinase, ... 著者 Gogl, G, Nyitray, L. 登録日 2017-02-20 公開日 2017-11-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Dynamic control of RSK complexes by phosphoswitch-based regulation. FEBS J., 285, 2018
5V6B	Crystal structure of GIPC1 分子名称: PDZ domain-containing protein GIPC1 著者 Shang, G, Zhang, X. 登録日 2017-03-16 公開日 2017-05-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex. Elife, 6, 2017
5XBF	Crystal Structure of Myo7b C-terminal MyTH4-FERM in complex with USH1C PDZ3 分子名称: ACETATE ION, D-MALATE, GLYCEROL, ... 著者 Li, J, He, Y, Weck, W.L, Lu, Q, Tyska, M.J, Zhang, M. 登録日 2017-03-17 公開日 2017-05-17 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V6T	The Plexin D1 intracellular region in complex with GIPC1 分子名称: PDZ domain-containing protein GIPC1, Plexin-D1, SULFATE ION 著者 Shang, G, Zhang, X. 登録日 2017-03-17 公開日 2017-05-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.189 Å) 主引用文献 Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex. Elife, 6, 2017
5VWC	Crystal structure of human Scribble PDZ1 domain 分子名称: 1,2-ETHANEDIOL, Protein scribble homolog 著者 Lim, K.Y.B, Kvansakul, M. 登録日 2017-05-21 公開日 2017-11-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.911 Å) 主引用文献 Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX. J. Biol. Chem., 292, 2017
5VWK	Crystal structure of human Scribble PDZ1:Beta-PIX complex 分子名称: Beta-PIX, Protein scribble homolog, SULFATE ION 著者 Lim, K.Y.B, Kvansakul, M. 登録日 2017-05-22 公開日 2017-11-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX. J. Biol. Chem., 292, 2017
5VWI	Crystal structure of human Scribble PDZ1:Beta-PIX complex 分子名称: Protein scribble homolog, beta-PIX 著者 Lim, K.Y.B, Kvansakul, M. 登録日 2017-05-22 公開日 2017-11-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX. J. Biol. Chem., 292, 2017
5W72	Impact of IR active probes on PDZ3 and its ligand binding studied by NMR and X-ray crystallography 分子名称: Disks large homolog 4 著者 Lehner, F, Kudlinzki, D, Schwalbe, H, Silvers, R. 登録日 2017-06-19 公開日 2017-12-13 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Impact of Azidohomoalanine Incorporation on Protein Structure and Ligand Binding. Chembiochem, 18, 2017
5OAK	Structure of the dmPar3 PDZ1 domain in complex with the dmPar6 PBM 分子名称: Bazooka, isoform C,LD29223p, GLYCEROL 著者 Bruekner, S.R, Wiesner, S. 登録日 2017-06-22 公開日 2018-02-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis for the interaction between the cell polarity proteins Par3 and Par6. Sci Signal, 11, 2018
5WOU	Crystal Structure of drosophila melanogaster Scribble PDZ1 domain in complex with Guk-Holder 分子名称: 1,2-ETHANEDIOL, GUK-holder, isoform A, ... 著者 Caria, S, Kvansakul, M. 登録日 2017-08-03 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Drosophila melanogasterGuk-holder interacts with the Scribbled PDZ1 domain and regulates epithelial development with Scribbled and Discs Large. J. Biol. Chem., 293, 2018
6AR4	Crystal structure of PICK1 in complex with the small molecule inhibitor 1o 分子名称: N-[4-(4-bromophenyl)-1-{[2-(trifluoromethyl)phenyl]methyl}piperidine-4-carbonyl]-3-cyclopropyl-L-alanine, PRKCA-binding protein 著者 Marcotte, D. 登録日 2017-08-21 公開日 2018-08-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction. Sci Rep, 8, 2018
6ESP	Proteome-wide analysis of phospho-regulated PDZ domain interactions 分子名称: Protein scribble homolog 著者 Chi, N.C. 登録日 2017-10-24 公開日 2018-09-05 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Proteome-wide analysis of phospho-regulated PDZ domain interactions. Mol. Syst. Biol., 14, 2018
6EW9	CRYSTAL STRUCTURE OF DEGS STRESS SENSOR PROTEASE IN COMPLEX WITH ACTIVATING DNRLGLVYQF PEPTIDE 分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, DNRLGLVYQF PEPTIDE, ... 著者 Vetter, I.R, Porfetye, A.T, Stege, P. 登録日 2017-11-03 公開日 2018-04-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent Probes. ACS Chem. Biol., 13, 2018
6BJO	PICK1 PDZ domain in complex with the small molecule inhibitor BIO124. 分子名称: (2S)-({4-(4-bromophenyl)-1-[1-(tert-butoxycarbonyl)-L-prolyl]piperidine-4-carbonyl}amino)(cyclopentyl)acetic acid, PRKCA-binding protein 著者 Marcotte, D.J. 登録日 2017-11-06 公開日 2018-01-10 最終更新日 2018-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure. Protein Sci., 27, 2018
6BJN	PICK1 PDZ domain in complex with the class I PDZ binding motif QSAV 分子名称: PRKCA-binding protein 著者 Marcotte, D.J. 登録日 2017-11-06 公開日 2018-01-10 最終更新日 2018-02-28 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure. Protein Sci., 27, 2018
6EZI	PDZK1 domain 4 in complex with C-terminal peptide of human PepT2. 分子名称: GLYCEROL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Solute carrier family 15 member 2 著者 Loew, C, Flayhan, A, Pieprzyk, J. 登録日 2017-11-15 公開日 2018-09-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.503321 Å) 主引用文献 Probing the Architecture of a Multi-PDZ Domain Protein: Structure of PDZK1 in Solution. Structure, 26, 2018
6BXG	1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide. 分子名称: CHLORIDE ION, IODIDE ION, LEU-ILE-ALA, ... 著者 Minasov, G, Shuvalova, L, Filippova, E.V, Kiryukhina, O, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-12-18 公開日 2018-01-03 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide. To Be Published
5ZDS	Crystal structure of the second PDZ domain of Frmpd2 分子名称: FERM and PDZ domain-containing 2 著者 Lu, X, Wang, X.F. 登録日 2018-02-24 公開日 2019-02-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The second PDZ domain of scaffold protein Frmpd2 binds to GluN2A of NMDA receptors. Biochem.Biophys.Res.Commun., 516, 2019

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