PDB: 731 件ウェブページステータス検索Chemie searchBIRD

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1BHI	STRUCTURE OF TRANSACTIVATION DOMAIN OF CRE-BP1/ATF-2, NMR, 20 STRUCTURES 分子名称: CRE-BP1 著者 Nagadoi, A, Nakazawa, K, Uda, H, Maekawa, T, Ishii, S, Nishimura, Y. 登録日 1998-06-09 公開日 1999-06-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the transactivation domain of ATF-2 comprising a zinc finger-like subdomain and a flexible subdomain. J.Mol.Biol., 287, 1999
1C1Y	CRYSTAL STRUCTURE OF RAP.GMPPNP IN COMPLEX WITH THE RAS-BINDING-DOMAIN OF C-RAF1 KINASE (RAFRBD). 分子名称: CALCIUM ION, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Nassar, N. 登録日 1999-07-22 公開日 1999-08-02 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue. Nature, 375, 1995
2LXT	Allosteric communication in the KIX domain proceeds through dynamic re-packing of the hydrophobic core 分子名称: CREB-binding protein, Cyclic AMP-responsive element-binding protein 1, Histone-lysine N-methyltransferase MLL 著者 Bruschweiler, S, Schanda, P, Konrat, R, Tollinger, M. 登録日 2012-08-31 公開日 2013-06-12 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Allosteric communication in the KIX domain proceeds through dynamic repacking of the hydrophobic core. Acs Chem.Biol., 8, 2013
8G23	Structure of Ternary Complex of cGAS with dsDNA and Bound pppIpA 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-02-03 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIM	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIP	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.040mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIN	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.015mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8G1J	Structure of Ternary Complex of cGAS with dsDNA and Bound ATP and ITP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Wu, S, Sohn, J. 登録日 2023-02-02 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8G2P	Structure of Ternary Complex of cGAS with dsDNA and Bound ATP and GTP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Wu, S, Sohn, J. 登録日 2023-02-06 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.521 Å) 主引用文献 Structure of Ternary Complex of cGAS with dsDNA and Bound ATP and GTP To Be Published
8SJ2	Structure of ternary complex of cGAS with dsDNA and bound ATP and 2'-dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ... 著者 Wu, S, Sohn, J. 登録日 2023-04-17 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8SJ0	Structure of ternary complex of cGAS with dsDNA and bound 2'-dATP 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-04-17 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8SKT	Structure of ternary complex of mouse cGAS with dsDNA and bound ATP with 5 mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-04-20 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8SHY	Structure of binary complex of mouse cGAS QN and bound ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ZINC ION 著者 Wu, S, Sohn, J. 登録日 2023-04-14 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8SHK	Structure of binary complex of mouse cGAS and bound ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ZINC ION 著者 Wu, S, Sohn, J. 登録日 2023-04-14 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8SJ1	Structure of ternary complex of cGAS with dsDNA and bound 3'-dATP 分子名称: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-04-17 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
6IRR	Solution structure of DISC1/ATF4 complex 分子名称: Disrupted in schizophrenia 1 homolog,Cyclic AMP-dependent transcription factor ATF-4 著者 Ye, F, Yu, C, Zhang, M. 登録日 2018-11-14 公開日 2019-09-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders. Mol. Psychiatry, 2019
1LPD	HIGH RESOLUTION STRUCTURE OF RECOMBINANT DIANTHIN ANTIVIRAL PROTEIN-POTENT ANTI-HIV AGENT (COMPLEX WITH ADENINE) 分子名称: ADENINE, Dianthin 30 著者 Kurinov, I.V, Rajamohan, F, Uckun, F.M. 登録日 2002-05-07 公開日 2004-05-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 High resolution X-ray structure and potent anti-HIV activity of recombinant dianthin antiviral protein. Arzneimittelforschung, 54, 2004
1LP8	HIGH RESOLUTION STRUCTURE OF RECOMBINANT DIANTHIN ANTIVIRAL PROTEIN-POTENT ANTI-HIV AGENT 分子名称: DIANTHIN 30 著者 Kurinov, I.V, Rajamohan, F, Uckun, F.M. 登録日 2002-05-07 公開日 2004-05-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 High resolution X-ray structure and potent anti-HIV activity of recombinant dianthin antiviral protein. Arzneimittelforschung, 54, 2004
7MWY	Structure of the drosophila STING cyclic dinucleotide binding domain 分子名称: STING 著者 Slavik, K.M, Ragucci, A.E, Kranzusch, P.J. 登録日 2021-05-17 公開日 2021-07-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila. Nature, 597, 2021
7MWZ	Structure of drosophila STING in complex with 3'2'-cGAMP 分子名称: 3'2'-cGAMP, STING 著者 Slavik, K.M, Ragucci, A.E, Kranzusch, P.J. 登録日 2021-05-17 公開日 2021-07-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila. Nature, 597, 2021
4X6R	An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... 著者 Zhang, P, Ye, F, Bastidas, A.C, Kornev, A.P, Ginsberg, M.H, Wu, J, Taylor, S.S. 登録日 2014-12-09 公開日 2015-07-22 最終更新日 2020-06-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes. Structure, 23, 2015
4X6Q	An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit 著者 Zhang, P, Ye, F, Bastidas, A.C, Kornev, A.P, Ginsberg, M.H, Taylor, S.S. 登録日 2014-12-08 公開日 2015-07-22 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes. Structure, 23, 2015
5KJZ	Co-crystal structure of PKA RI alpha CNB-B mutant (G316R/A336T) with cGMP 分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, cAMP-dependent protein kinase type I-alpha regulatory subunit 著者 Lorenz, R, Moon, E, Kim, J.J, Huang, G.Y, Kim, C, Herberg, F.W. 登録日 2016-06-20 公開日 2017-06-28 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.347 Å) 主引用文献 Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity. Biochem. J., 474, 2017
6HVL	CdaA complex with c-di-AMP and AMP 分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ADENOSINE MONOPHOSPHATE, COBALT (II) ION, ... 著者 Heidemann, J.L, Neumann, P, Ficner, R. 登録日 2018-10-11 公開日 2019-06-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures of the c-di-AMP-synthesizing enzyme CdaA. J.Biol.Chem., 294, 2019
5KHI	HCN2 CNBD in complex with purine riboside-3', 5'-cyclic monophosphate (cPuMP) 分子名称: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, Purine riboside-3',5'-cyclic monophosphate 著者 Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A. 登録日 2016-06-14 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening. Structure, 24, 2016

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