PDB: 236963 件ウェブページステータス検索Chemie searchBIRD

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5WAS	Corynebacterium glutamicum Hydrolyzed Homoserine kinase 分子名称: Homoserine kinase, PHOSPHATE ION 著者 Petit, C, Ronning, D.R. 登録日 2017-06-27 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Reduction of Feedback Inhibition in Homoserine Kinase (ThrB) ofCorynebacterium glutamicumEnhances l-Threonine Biosynthesis. ACS Omega, 3, 2018
7NHH	Crystal structure of the human METTL3-METTL14 complex with compound UOZ002 分子名称: (R)-N-((3-hydroxy-1-(6-(methylamino)pyrimidin-4-yl)piperidin-3-yl)methyl)-4-((4-methylpiperidin-1-yl)methyl)benzamide, ACETATE ION, MAGNESIUM ION, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-10 公開日 2021-10-20 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
7NI7	Crystal structure of the human METTL3-METTL14 complex with compound UOZ031 分子名称: (R)-4-((4,4-dimethylpiperidin-1-yl)methyl)-2-hydroxy-N-((3-hydroxy-1-(6-((3-(methylcarbamoyl)benzyl)amino)pyrimidin-4-yl)piperidin-3-yl)methyl)benzamide, ACETATE ION, MAGNESIUM ION, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-11 公開日 2021-10-20 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
7NID	Crystal structure of the human METTL3-METTL14 complex with compound UOZ078 分子名称: (R)-1-(6-(benzylamino)pyrimidin-4-yl)-3-(((6-((4,4-dimethylpiperidin-1-yl)methyl)naphthalen-1-yl)amino)methyl)piperidin-3-ol, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-11 公開日 2021-10-20 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
7NHJ	Crystal structure of the human METTL3-METTL14 complex with compound DHU_M3M_154 分子名称: (S)-3-(((6-(3-(hydroxymethyl)piperidin-1-yl)pyrimidin-4-yl)amino)methyl)benzenesulfonamide, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-10 公開日 2021-10-20 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
1ZS4	Structure of bacteriophage lambda cII protein in complex with DNA 分子名称: DNA - 27mer, Regulatory protein CII 著者 Jain, D, Kim, Y, Maxwell, K.L, Beasley, S, Gussin, G.N, Edwards, A.M, Darst, S.A. 登録日 2005-05-23 公開日 2005-08-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of Bacteriophage lambdacII and Its DNA Complex. Mol.Cell, 19, 2005
7NIA	Crystal structure of the human METTL3-METTL14 complex with compound UOZ059a 分子名称: 4-[[(3R)-3-cyclopropyl-2-azaspiro[3.3]heptan-2-yl]methyl]-N-[[(3R)-3-oxidanyl-1-[6-[(phenylmethyl)amino]pyrimidin-4-yl]piperidin-3-yl]methyl]benzamide, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-11 公開日 2021-10-20 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
7NI9	Crystal structure of the human METTL3-METTL14 complex with compound UOZ058 分子名称: ACETATE ION, N-(((R)-1-(6-(benzylamino)pyrimidin-4-yl)-3-hydroxypiperidin-3-yl)methyl)-4-(((S)-1-isopropyl-2-azaspiro[3.3]heptan-2-yl)methyl)benzamide, N6-adenosine-methyltransferase catalytic subunit, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-11 公開日 2021-10-20 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
3NZZ	Crystal Structure of the Salmonella Type III Secretion System Tip Protein SipD 分子名称: Cell invasion protein sipD, NICKEL (II) ION 著者 Chatterjee, S, Zhong, D, Nordhues, B.A, Battaile, K.P, Lovell, S, DeGuzman, R.N. 登録日 2010-07-18 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The crystal structures of the Salmonella type III secretion system tip protein SipD in complex with deoxycholate and chenodeoxycholate. Protein Sci., 20, 2011
7NI8	Crystal structure of the human METTL3-METTL14 complex with compound UOZ040a 分子名称: (R)-4-((2-azaspiro[3.3]heptan-2-yl)methyl)-N-((1-(6-(benzylamino)pyrimidin-4-yl)-3-hydroxypiperidin-3-yl)methyl)benzamide, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... 著者 Bedi, R.K, Huang, D, Caflisch, A. 登録日 2021-02-11 公開日 2021-10-20 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3 Acs Bio Med Chem Au, 2023
5EP2	Quorum-Sensing Signal Integrator LuxO - Catalytic Domain in Complex with AzaU Inhibitor 分子名称: 2,2-dimethylpropyl 2-[[3,5-bis(oxidanylidene)-2~{H}-1,2,4-triazin-6-yl]sulfanyl]ethanoate, ACETATE ION, Putative repressor protein luxO 著者 Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. 登録日 2015-11-11 公開日 2016-04-20 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.421 Å) 主引用文献 Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. Plos Biol., 14, 2016
6JVU	Crystal structure of Klebsiella pneumoniae CysE in complex with L-cysteine 分子名称: 1,2-ETHANEDIOL, CYSTEINE, PHOSPHATE ION, ... 著者 Verma, D, Gupta, V. 登録日 2019-04-17 公開日 2020-02-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Allosteric inhibition and kinetic characterization of Klebsiella pneumoniae CysE: An emerging drug target. Int.J.Biol.Macromol., 151, 2020
3UFB	Crystal structure of a modification subunit of a putative type I restriction enzyme from Vibrio vulnificus YJ016 分子名称: Type I restriction-modification system methyltransferase subunit 著者 Park, S.Y, Lee, H.J, Sun, J, Nishi, K, Song, J.M, Kim, J.S. 登録日 2011-11-01 公開日 2012-11-07 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural characterization of a modification subunit of a putative type I restriction enzyme from Vibrio vulnificus YJ016 Acta Crystallogr.,Sect.D, 68, 2012
7EH2	Thermus thermophilus transcription initiation complex containing a template-strand pyrimidine at position TSS-2 and GpG RNA primer 分子名称: DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Li, L, Zhang, Y. 登録日 2021-03-27 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.34 Å) 主引用文献 Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7DZD	Crystal structure of uPA in complex with cleaved camostat 分子名称: 4-carbamimidamidobenzoic acid, TRIETHYLENE GLYCOL, Urokinase-type plasminogen activator 著者 Jiang, L.G, Huang, M.D. 登録日 2021-01-25 公開日 2021-07-14 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of uPA in complex with cleaved camostat To Be Published
5EHC	Co-crystal structure of eIF4E with nucleotide mimetic inhibitor. 分子名称: 3-[[(2~{R},3~{S},4~{R},5~{R})-5-[2-azanyl-7-[(3-chlorophenyl)methyl]-6-oxidanylidene-1~{H}-purin-7-ium-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylamino]-4-oxidanyl-cyclobut-3-ene-1,2-dione, Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E 著者 Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M. 登録日 2015-10-28 公開日 2016-09-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur.J.Med.Chem., 124, 2016
4GXV	Crystal structure of anti-influenza virus antibody 1F1 分子名称: Antibody 1F1, heavy chain, light chain 著者 Ekiert, D.C, Wilson, I.A. 登録日 2012-09-04 公開日 2012-12-19 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.449 Å) 主引用文献 Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses. Plos Pathog., 8, 2012
1ZSE	RNA stemloop from bacteriophage Qbeta complexed with an N87S mutant MS2 Capsid 分子名称: Coat protein, RNA HAIRPIN 著者 Horn, W.T, Tars, K, Grahn, E, Helgstrand, C, Baron, A.J, Lago, H, Adams, C.J, Peabody, D.S, Phillips, S.E.V, Stonehouse, N.J, Liljas, L, Stockley, P.G. 登録日 2005-05-24 公開日 2006-05-09 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Basis of RNA Binding Discrimination between Bacteriophages Qbeta and MS2 Structure, 14, 2006
3UJA	Phosphoethanolamine methyltransferase from Plasmodium falciparum in complex with phosphoethanolamine 分子名称: PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, Phosphoethanolamine N-methyltransferase 著者 Lee, S.G, Kim, Y, Alpert, T.D, Nagata, A, Jez, J.M. 登録日 2011-11-07 公開日 2011-11-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.466 Å) 主引用文献 Structure and reaction mechanism of phosphoethanolamine methyltransferase from the malaria parasite Plasmodium falciparum: an antiparasitic drug target. J.Biol.Chem., 287, 2012
3HAS	Crystal structure of bacteriorhodopsin mutant L152A crystallized from bicelles 分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Bacteriorhodopsin, DECANE, ... 著者 Joh, N.H, Yang, D, Bowie, J.U. 登録日 2009-05-02 公開日 2009-09-22 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Similar energetic contributions of packing in the core of membrane and water-soluble proteins. J.Am.Chem.Soc., 131, 2009
3UD3	The C92U mutant c-di-GMP-I riboswitch bound to pGpA 分子名称: MAGNESIUM ION, RNA (5'-R(P*GP*A)-3'), RNA (92-MER), ... 著者 Smith, K.D, Strobel, S.A. 登録日 2011-10-27 公開日 2012-01-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural and biochemical characterization of linear dinucleotide analogues bound to the c-di-GMP-I aptamer. Biochemistry, 51, 2012
6FQL	Crystal structure of Danio rerio Lin41 filamin-NHL domains in complex with mab-10 3'UTR 13mer RNA 分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase TRIM71, RNA (5'-R(*UP*GP*CP*AP*UP*UP*UP*AP*AP*UP*GP*CP*A)-3') 著者 Kumari, P, Aeschimann, F, Gaidatzis, D, Keusch, J.J, Ghosh, P, Neagu, A, Pachulska-Wieczorek, K, Bujnicki, J.M, Gut, H, Grosshans, H, Ciosk, R. 登録日 2018-02-14 公開日 2018-05-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.349 Å) 主引用文献 Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition. Nat Commun, 9, 2018
3H74	Crystal structure of pyridoxal kinase from Lactobacillus plantarum 分子名称: GLYCEROL, Pyridoxal kinase, SULFATE ION 著者 Bagaria, A, Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-04-24 公開日 2009-05-26 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of pyridoxal kinase from Lactobacillus plantarum To be Published
3HGG	Crystal Structure of CmeR Bound to Cholic Acid 分子名称: CHOLIC ACID, CmeR 著者 Routh, M.D, Yang, F. 登録日 2009-05-13 公開日 2010-06-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Structural basis for anionic ligand recognition by multidrug binding proteins: Crystal structures of CmeR-bile acid complexes To be Published
3LF0	Crystal structure of the ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Nitrogen regulatory protein P-II 著者 Shetty, N.D, Palaninathan, S.K, Reddy, M.C.M, Owen, J.L, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2010-01-15 公開日 2010-07-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures of the apo and ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein. Protein Sci., 19, 2010

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