PDB: 10243 件ウェブページステータス検索Chemie searchBIRD

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5OMY	HIGH-SALT STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA) IN COMPLEX WITH THE INDENOINDOLE-TYPE INHIBITOR 4P 分子名称: 4-(3-methylbut-2-enoxy)-5-propan-2-yl-7,8-dihydro-6~{H}-indeno[1,2-b]indole-9,10-dione, CHLORIDE ION, Casein kinase II subunit alpha 著者 Hochscherf, J, Lindenblatt, D, Witulski, B, Birus, R, Aichele, D, Marminon, C, Bouaziz, Z, Le Borgne, M, Jose, J, Niefind, K. 登録日 2017-08-02 公開日 2017-12-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2 alpha and Its Paralog CK2 alpha '. Pharmaceuticals (Basel), 10, 2017
5ONI	LOW-SALT STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA) IN COMPLEX WITH THE INDENOINDOLE-TYPE INHIBITOR 4P 分子名称: 1,4-BUTANEDIOL, 4-(3-methylbut-2-enoxy)-5-propan-2-yl-7,8-dihydro-6~{H}-indeno[1,2-b]indole-9,10-dione, CHLORIDE ION, ... 著者 Hochscherf, J, Lindenblatt, D, Witulski, B, Birus, R, Aichele, D, Marminon, C, Bouaziz, Z, Le Borgne, M, Jose, J, Niefind, K. 登録日 2017-08-03 公開日 2017-12-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2 alpha and Its Paralog CK2 alpha '. Pharmaceuticals (Basel), 10, 2017
5EG0	HOXB13-MEIS1 heterodimer bound to DNA 分子名称: DNA (5'-D(*CP*CP*TP*CP*GP*TP*AP*AP*AP*AP*CP*TP*GP*TP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*AP*CP*AP*GP*TP*TP*TP*TP*AP*CP*GP*AP*GP*G)-3'), Homeobox protein Hox-B13, ... 著者 Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J. 登録日 2015-10-26 公開日 2016-11-09 最終更新日 2025-04-23 実験手法 X-RAY DIFFRACTION (3.101 Å) 主引用文献 DNA-guided transcription factor interactions extend human gene regulatory code. Nature, 2025
8CYV	CryoEM structures of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case II 分子名称: Alpha-synuclein 著者 Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A. 登録日 2022-05-24 公開日 2023-05-31 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid To Be Published
4DFZ	Crystal structure of myristoylated K7C catalytic subunit of cAMP-dependent protein kinase in complex with SP20 分子名称: MYRISTIC ACID, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha 著者 Bastidas, A.C, Steichen, J.M, Taylor, S.S. 登録日 2012-01-24 公開日 2012-06-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase. J.Mol.Biol., 422, 2012
5BWM	The complex structure of C3cer exoenzyme and GDP bound RhoA (NADH-bound state) 分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADP-ribosyltransferase, ... 著者 Toda, A, Tsurumura, T, Yoshida, T, Tsuge, H. 登録日 2015-06-08 公開日 2015-06-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure. J.Biol.Chem., 290, 2015
4DG0	Crystal structure of myristoylated WT catalytic subunit of cAMP-dependent protein kinase in complex with SP20 and AMP-PNP 分子名称: MAGNESIUM ION, MYRISTIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Bastidas, A.C, Steichen, J.M, Taylor, S.S. 登録日 2012-01-24 公開日 2012-06-06 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase. J.Mol.Biol., 422, 2012
4TRQ	Crystal structure of Sac3/Thp1/Sem1 分子名称: 26S proteasome complex subunit SEM1, Nuclear mRNA export protein SAC3, Nuclear mRNA export protein THP1, ... 著者 Hellerschmied, D, Schneider, S, Kohler, A, Clausen, T. 登録日 2014-06-17 公開日 2015-08-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression. Cell, 162, 2015
4MDE	Structure of bacterial polynucleotide kinase product complex bound to GDP and DNA 分子名称: DNA (5'-D(P*CP*CP*TP*GP*T)-3'), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Shuman, S, Das, U, Wang, L.K, Smith, P, Jacewicz, A. 登録日 2013-08-22 公開日 2013-11-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of bacterial polynucleotide kinase in a Michaelis complex with GTP*Mg2+ and 5'-OH oligonucleotide and a product complex with GDP*Mg2+ and 5'-PO4 oligonucleotide reveal a mechanism of general acid-base catalysis and the determinants of phosphoacceptor recognition. Nucleic Acids Res., 42, 2014
6TLP	HUMAN CK2 KINASE ALPHA SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE INHIBITOR 5,6-DIBROMOBENZOTRIAZOLE 分子名称: 5,6-DIBROMOBENZOTRIAZOLE, CITRATE ANION, Casein kinase II subunit alpha, ... 著者 Czapinska, H, Piasecka, A, Winiewska-Szajewska, M, Bochtler, M, Poznanski, J. 登録日 2019-12-03 公開日 2020-12-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Halogen Atoms in the Protein-Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2. J.Phys.Chem.B, 125, 2021
1IZ3	Dimeric structure of FIH (Factor inhibiting HIF) 分子名称: FIH, SULFATE ION 著者 Lee, C, Kim, S.-J, Jeong, D.-G, Lee, S.M, Ryu, S.-E. 登録日 2002-09-19 公開日 2003-06-10 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau. J.Biol.Chem., 278, 2003
4DFX	Crystal structure of myristoylated K7C catalytic subunit of cAMP-dependent protein kinase in complex with SP20 and AMP-PNP 分子名称: GLYCEROL, MAGNESIUM ION, MYRISTIC ACID, ... 著者 Bastidas, A.C, Steichen, J.M, Taylor, S.S. 登録日 2012-01-24 公開日 2012-06-06 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase. J.Mol.Biol., 422, 2012
7RQV	Cryo-EM structure of the full-length TRPV1 with RTx at 4 degrees Celsius, in an intermediate-closed state, class II 分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ... 著者 Kwon, D.H, Suo, Y, Lee, S.-Y. 登録日 2021-08-08 公開日 2022-06-01 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis. Nat Commun, 13, 2022
8UKP	cAMP-dependent protein kinase A catalytic domain in complex with voltage gated calcium channel peptide ternary complex 1 分子名称: ARG-GLY-PHE-LEU-ARG-SER-ALA-SER-LEU-GLY-ARG-ARG-ALA-SER-PHE-HIS-LEU, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Haji-Ghassemi, O, Van Petegem, F. 登録日 2023-10-14 公開日 2024-12-11 最終更新日 2025-01-01 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Crystallographic, kinetic, and calorimetric investigation of PKA interactions with L-type calcium channels and Rad GTPase. J.Biol.Chem., 301, 2024
8UKO	cAMP-dependent protein kinase A catalytic domain in complex with voltage gated calcium channel peptide ternary complex 2 分子名称: ARG-GLY-PHE-LEU-ARG-SER-ALA-SER-LEU-GLY-ARG-ARG-ALA-SER-PHE-HIS-LEU, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Haji-Ghassemi, O, Van Petegem, F. 登録日 2023-10-14 公開日 2024-12-11 最終更新日 2025-01-01 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Crystallographic, kinetic, and calorimetric investigation of PKA interactions with L-type calcium channels and Rad GTPase. J.Biol.Chem., 301, 2024
2XPP	Crystal structure of a Spt6-Iws1(Spn1) complex from Encephalitozoon cuniculi, Form III 分子名称: CHROMATIN STRUCTURE MODULATOR, IWS1 著者 Diebold, M.-L, Koch, M, Cura, V, Cavarelli, J, Romier, C. 登録日 2010-08-27 公開日 2010-11-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 The Structure of an Iws1/Spt6 Complex Reveals an Interaction Domain Conserved in Tfiis, Elongin a and Med26 Embo J., 29, 2010
4QJD	Crystal Structure of Twister with the Nucleotide 5'- to the Cleavage Site Disordered at 3.1 A Resolution 分子名称: MAGNESIUM ION, Twister RNA sequence 著者 Eiler, D.R, Wang, J, Steitz, T.A. 登録日 2014-06-03 公開日 2014-09-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis for the fast self-cleavage reaction catalyzed by the twister ribozyme. Proc.Natl.Acad.Sci.USA, 111, 2014
4MVA	1.43 Angstrom Resolution Crystal Structure of Triosephosphate Isomerase (tpiA) from Escherichia coli in Complex with Acetyl Phosphate. 分子名称: 1,2-ETHANEDIOL, ACETYLPHOSPHATE, CHLORIDE ION, ... 著者 Minasov, G, Kuhn, M.L, Dubrovska, I, Winsor, J, Shuvalova, L, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2013-09-23 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation. Plos One, 9, 2014
2XN9	Crystal structure of the ternary complex between human T cell receptor, staphylococcal enterotoxin H and human major histocompatibility complex class II 分子名称: ENTEROTOXIN H, GLYCEROL, HEMAGGLUTININ, ... 著者 Saline, M, Rodstrom, K.E.J, Fischer, G, Orekhov, V.Y, Karlsson, B.G, Lindkvist-Petersson, K. 登録日 2010-07-31 公開日 2010-11-24 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Structure of Superantigen Complexed with Tcr and Mhc Reveals Novel Insights Into Superantigenic T Cell Activation. Nat.Commun., 1, 2010
3QER	RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dATP Opposite Difluorotoluene Nucleoside 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-01-20 公開日 2012-01-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue. Biochemistry, 51, 2012
2QVU	Porcine Liver Fructose-1,6-bisphosphatase cocrystallized with Fru-2,6-P2 and Mg2+, I(T)-state 分子名称: 2,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION, ... 著者 Hines, J.K, Chen, X, Nix, J.C, Fromm, H.J, Honzatko, R.B. 登録日 2007-08-08 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structures of mammalian and bacterial fructose-1,6-bisphosphatase reveal the basis for synergism in AMP/fructose 2,6-bisphosphate inhibition J.Biol.Chem., 282, 2007
3QEI	RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dCTP Opposite Difluorotoluene Nucleoside 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-01-20 公開日 2012-01-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.178 Å) 主引用文献 Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue. Biochemistry, 51, 2012
2XPN	Crystal structure of a Spt6-Iws1(Spn1) complex from Encephalitozoon cuniculi, Form I 分子名称: BROMIDE ION, CHROMATIN STRUCTURE MODULATOR, IWS1 著者 Diebold, M.-L, Koch, M, Cura, V, Cavarelli, J, Romier, C. 登録日 2010-08-27 公開日 2010-11-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The Structure of an Iws1/Spt6 Complex Reveals an Interaction Domain Conserved in Tfiis, Elongin a and Med26 Embo J., 29, 2010
9CHU	Cryo-EM structure of calcineurin fused beta2 adrenergic receptor in norepinephrine bound inactive state 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, Beta-2 adrenergic receptor,Calcineurin subunit B type 1, Noradrenaline, ... 著者 Xu, J, Chen, G, Du, Y, Kobilka, B.K. 登録日 2024-07-02 公開日 2024-11-13 最終更新日 2024-11-27 実験手法 ELECTRON MICROSCOPY (3.49 Å) 主引用文献 Calcineurin-fusion facilitates cryo-EM structure determination of a Family A GPCR. Proc.Natl.Acad.Sci.USA, 121, 2024
9CHX	cryo-EM structure of calcineurin-fused beta2 adrenergic receptor in carazolol bound inactive state 分子名称: (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, Beta-2 adrenergic receptor,Calcineurin subunit B type 1, ... 著者 Xu, J, Chen, G, Du, Y, Kobilka, B.K. 登録日 2024-07-02 公開日 2024-11-13 最終更新日 2024-11-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Calcineurin-fusion facilitates cryo-EM structure determination of a Family A GPCR. Proc.Natl.Acad.Sci.USA, 121, 2024

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