PDB: 229040 件ウェブページステータス検索Chemie searchBIRD

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9BH6	Human DNA polymerase theta helicase domain tetramer in the apo form 分子名称: DNA polymerase theta 著者 Zerio, C.J, Lander, G.C. 登録日 2024-04-19 公開日 2024-05-01 最終更新日 2025-03-12 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Human polymerase theta helicase positions DNA microhomologies for double-strand break repair. Nat.Struct.Mol.Biol., 2025
5N02	Crystal structure of the decarboxylase AibA/AibB C56S variant 分子名称: ACETATE ION, Glutaconate CoA-transferase family, subunit A, ... 著者 Bock, T, Luxenburger, E, Hoffmann, J, Schuetza, V, Feiler, C, Mueller, R, Blankenfeldt, W. 登録日 2017-02-02 公開日 2017-05-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 AibA/AibB Induces an Intramolecular Decarboxylation in Isovalerate Biosynthesis by Myxococcus xanthus. Angew. Chem. Int. Ed. Engl., 56, 2017
9BHA	Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology annealed conformation 分子名称: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang 著者 Zerio, C.J, Lander, G.C. 登録日 2024-04-19 公開日 2024-05-01 最終更新日 2025-03-12 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Human polymerase theta helicase positions DNA microhomologies for double-strand break repair. Nat.Struct.Mol.Biol., 2025
2JST	Four-Alpha-Helix Bundle with Designed Anesthetic Binding Pockets II: Halothane Effects on Structure and Dynamics 分子名称: 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE, Four-Alpha-Helix Bundle 著者 Cui, T, Bondarenko, V, Ma, D, Canlas, C, Brandon, N.R, Johansson, J.S, Tang, P, Xu, Y. 登録日 2007-07-12 公開日 2008-05-27 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Four-alpha-helix bundle with designed anesthetic binding pockets. Part II: halothane effects on structure and dynamics Biophys.J., 94, 2008
5NJR	Mix-and-diffuse serial synchrotron crystallography: structure of N,N',N''-Triacetylchitotriose bound to Lysozyme with 50s time-delay, phased with 4ET8 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Lysozyme C, ... 著者 Oberthuer, D, Meents, A, Beyerlein, K.R, Chapman, H.N, Lieseke, J. 登録日 2017-03-29 公開日 2017-10-18 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mix-and-diffuse serial synchrotron crystallography. IUCrJ, 4, 2017
7RP8	X-ray crystal structure of OXA-24/40 K84D in complex with imipenem 分子名称: Beta-lactamase, Imipenem, SULFATE ION 著者 Powers, R.A, Mitchell, J.M, June, C.M. 登録日 2021-08-03 公開日 2022-07-06 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Conformational flexibility in carbapenem hydrolysis drives substrate specificity of the class D carbapenemase OXA-24/40. J.Biol.Chem., 298, 2022
9BHR	Crystal structure of the WDR domain of human DCAF1 in complex with OICR-40155 compound 分子名称: (4P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-4-(4-chloro-2-fluorophenyl)-5-{(1E)-3-[(2-methoxyethyl)amino]-3-oxoprop-1-en-1-yl}-1H-pyrrole-3-carboxamide, DDB1- and CUL4-associated factor 1 著者 kimani, S, Dong, A, Li, Y, Seitova, A, Al-Awar, R, Krausser, C, Wilson, B, Ackloo, S, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) 登録日 2024-04-21 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Crystal structure of the WDR domain of human DCAF1 in complex with OICR-40155 compound To be published
1AG0	STRUCTURE OF CYS 112 ASP AZURIN FROM PSEUDOMONAS AERUGINOSA 分子名称: AZURIN, COPPER (II) ION 著者 Faham, S, Rees, D.C. 登録日 1997-03-26 公開日 1997-10-29 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Role of the Active-Site Cysteine of Pseudomonas Aeruginosa Azurin. Crystal Structure Analysis of the Cu(II) Cys112Asp Protein To be Published
5BYW	Crystal structure of engineered trifunctional CtCEL5E 分子名称: Endoglucanase H 著者 Lin, W.L, Liang, P.H, Ho, M.C. 登録日 2015-06-11 公開日 2016-06-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of engineered trifunctional CtCel5E to be published
6RKI	Fragment AZ-023 binding at the p53pT387/14-3-3 sigma interface 分子名称: 14-3-3 protein sigma, 5-[(3-aminophenyl)amino]-4-phenyl-thiophene-2-carboximidamide, CHLORIDE ION, ... 著者 Genet, S, Wolter, M, Guillory, X, Somsen, B, Leysen, S, Castaldi, P, Ottmann, C. 登録日 2019-04-30 公開日 2020-06-17 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
3HSQ	Structural Basis for the Sugar Nucleotide and Acyl Chain Selectivity of Leptospira interrogans LpxA 分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase 著者 Robins, L.I, Williams, A.H, Raetz, C.R. 登録日 2009-06-10 公開日 2009-09-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for the sugar nucleotide and acyl-chain selectivity of Leptospira interrogans LpxA. Biochemistry, 48, 2009
5N5M	Crystal structure of human Pim-1 kinase in complex with a consensuspeptide and (R)-3-(2-((isoquinolin-5-ylmethyl)(methyl)carbamoyl)phenyl)pyrrolidin-1-ium 分子名称: Pimtide, Serine/threonine-protein kinase pim-1, ~{N}-(isoquinolin-5-ylmethyl)-~{N}-methyl-2-[(3~{R})-pyrrolidin-3-yl]benzamide 著者 Siefker, C, Heine, A, Klebe, G. 登録日 2017-02-14 公開日 2018-03-07 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 A crystallographic fragment study with human Pim-1 kinase to be published
6RKM	Fragment AZ-022 binding at the p53pT387/14-3-3 sigma interface 分子名称: 14-3-3 protein sigma, 4-phenyl-5-phenylazanyl-thiophene-2-carboximidamide, CHLORIDE ION, ... 著者 Genet, S, Wolter, M, Guillory, X, Somsen, B, Leysen, S, Patel, J, Castaldi, P, Ottmann, C. 登録日 2019-04-30 公開日 2020-06-17 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
2BRC	Structure of a Hsp90 Inhibitor bound to the N-terminus of Yeast Hsp90. 分子名称: 4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 著者 Roe, S.M, Pearl, L.H, Prodromou, C. 登録日 2005-05-04 公開日 2005-09-29 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors. Bioorg. Med. Chem. Lett., 15, 2005
5N5W	14-3-3 sigma in complex with TAZ pS89 peptide and fragment NV3 分子名称: 14-3-3 protein sigma, 4-[3,5-bis(chloranyl)pyridin-2-yl]oxyaniline, CALCIUM ION, ... 著者 Sijbesma, E, Leysen, S, Ottmann, C. 登録日 2017-02-14 公開日 2017-07-19 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Identification of Two Secondary Ligand Binding Sites in 14-3-3 Proteins Using Fragment Screening. Biochemistry, 56, 2017
6RL4	Fragment AZ-025 binding at the p53pT387/14-3-3 sigma interface 分子名称: 14-3-3 protein sigma, 5-[1-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide, CHLORIDE ION, ... 著者 Genet, S, Wolter, M, Guillory, X, Somsen, B, Leysen, S, Patel, J, Castaldi, P, Ottmann, C. 登録日 2019-05-01 公開日 2020-06-17 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
5NLD	Chicken GRIFIN (crystallisation pH: 7.5) 分子名称: Galectin, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose 著者 Ruiz, F.M, Romero, A. 登録日 2017-04-04 公開日 2018-02-14 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (0.96 Å) 主引用文献 Chicken GRIFIN: Structural characterization in crystals and in solution. Biochimie, 146, 2018
3P6P	Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC1-C6-Bio 分子名称: (3S,5S,7S)-N-[6-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)hexyl]tricyclo[3.3.1.1~3,7~]decane-1-carboxamide, Camphor 5-monooxygenase, POTASSIUM ION, ... 著者 Lee, Y.-T, Wilson, R.F, Glazer, E.C, Goodin, D.B. 登録日 2010-10-11 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC1-C6-Bio To be Published
2C2U	Dps from Deinococcus radiodurans 分子名称: DNA-BINDING STRESS RESPONSE PROTEIN, FE (III) ION, SULFATE ION, ... 著者 Romao, C.V, Mitchell, E, McSweeney, S. 登録日 2005-09-30 公開日 2006-07-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 The Crystal Structure of Deinococcus Radiodurans Dps Protein (Dr2263) Reveals the Presence of a Novel Metal Centre in the N Terminus. J.Biol.Inorg.Chem., 11, 2006
3P04	Crystal Structure of the BCR protein from Corynebacterium glutamicum. Northeast Structural Genomics Consortium Target CgR8 分子名称: Uncharacterized BCR 著者 Vorobiev, S, Lew, S, Seetharaman, J, Hamilton, H, Xiao, R, Patel, D.J, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2010-09-27 公開日 2010-10-13 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the BCR protein from Corynebacterium glutamicum. Northeast Structural Genomics Consortium Target CgR8. To be Published
5CHG	Human DNA polymerase lambda L431A mutant- MgdGTP binary and complex with 6 paired DNA 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), ... 著者 Liu, M.S, Tsai, M.D. 登録日 2015-07-10 公開日 2016-02-24 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda J.Am.Chem.Soc., 138, 2016
9EHI	Crystal structure of ENL YEATS in complex with histone H3 methacrylated at K18 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Histone H3.1, Protein ENL 著者 Becht, D.C, Selvam, K, Kutateladze, T.G. 登録日 2024-11-22 公開日 2025-04-09 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of ENL YEATS in complex with histone H3 methacrylated at K18 To Be Published
1EB8	Structure Determinants of Substrate Specificity of Hydroxynitrile Lyase from Manihot esculenta 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, (S)-ACETONE-CYANOHYDRIN LYASE 著者 Lauble, H, Miehlich, B, Foerster, S, Kobler, C, Wajant, H, Effenberger, F. 登録日 2001-07-24 公開日 2002-01-01 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure Determinants of Substrate Specificity of Hydroxynitrile Lyase from Manihot Esculenta. Protein Sci., 11, 2002
5C14	Crystal structure of PECAM-1 D1D2 domain 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... 著者 Zhou, D, Paddock, C, Newman, P, Zhu, J. 登録日 2015-06-12 公開日 2016-01-06 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for PECAM-1 homophilic binding. Blood, 127, 2016
7S4F	Protein Tyrosine Phosphatase 1B - F182Q mutant bound with Hepes 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, MAGNESIUM ION, ... 著者 Brandao, T.A.S, Hengge, A.C, Johnson, S.J. 登録日 2021-09-08 公開日 2022-09-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Insights into the importance of WPD-loop sequence for activity and structure in protein tyrosine phosphatases. Chem Sci, 13, 2022

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