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6C1A
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BU of 6c1a by Molmil
MBD2 in complex with methylated DNA
分子名称: Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION, complement to dna strand 1, ...
著者Liu, K, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2018-01-04
公開日2018-02-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
J. Biol. Chem., 293, 2018
6C1T
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BU of 6c1t by Molmil
MBD2 in complex with a partially methylated DNA
分子名称: 12-mer DNA, GLYCEROL, Methyl-CpG-binding domain protein 2, ...
著者Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2018-01-05
公開日2018-02-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
J. Biol. Chem., 293, 2018
2Y1I
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BU of 2y1i by Molmil
Crystal structure of a S-diastereomer analogue of the spore photoproduct in complex with fragment DNA polymerase I from Bacillus stearothermophilus
分子名称: 5'-D(*AP*GP*GP*GP*PBTP*THM*GP*GP*TP*CP)-3', 5'-D(*GP*AP*CP*CP*AP*AP*CP*CP*CP*TP)-3', DNA POLYMERASE I, ...
著者Heil, K, Schneider, S, Mueller, M, Kneuttinger, A.C, Carell, T.
登録日2010-12-08
公開日2011-07-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Crystal Structures and Repair Studies Reveal the Identity and the Base-Pairing Properties of the Uv-Induced Spore Photoproduct DNA Lesion.
Chemistry, 17, 2011
2VEQ
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BU of 2veq by Molmil
Insights into kinetochore-DNA interactions from the structure of Cep3p
分子名称: BETA-MERCAPTOETHANOL, CACODYLATE ION, CENTROMERE DNA-BINDING PROTEIN COMPLEX CBF3 SUBUNIT B
著者Purvis, A, Singleton, M.R.
登録日2007-10-26
公開日2007-12-25
最終更新日2017-07-12
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Insights Into Kinetochore-DNA Interactions from the Structure of Cep3Delta
Embo Rep., 9, 2008
5INM
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BU of 5inm by Molmil
Mouse Tdp2 protein, apo state with variable DNA-binding grasp conformations
分子名称: GLYCEROL, MAGNESIUM ION, SULFATE ION, ...
著者Schellenberg, M.J, Williams, R.S.
登録日2016-03-07
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
6WE9
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BU of 6we9 by Molmil
YTH domain of human YTHDC1 with 11mer ssDNA Containing N6mA
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*CP*GP*GP*(6MA)P*CP*TP*CP*TP*G)-3'), GLYCEROL, ...
著者Horton, J.R, Cheng, X.
登録日2020-04-01
公開日2020-07-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Biochemical and structural basis for YTH domain of human YTHDC1 binding to methylated adenine in DNA.
Nucleic Acids Res., 48, 2020
5INL
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BU of 5inl by Molmil
Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex with deoxyadenosine
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, DNA (5'-D(P*AP*CP*GP*AP*AP*TP*TP*CP*G)-3'), ...
著者Schellenberg, M.J, Vilas, C.K, Williams, R.S.
登録日2016-03-07
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.551 Å)
主引用文献Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
5INQ
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BU of 5inq by Molmil
Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Ca2+ complex
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Schellenberg, M.J, Williams, R.S.
登録日2016-03-07
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.848 Å)
主引用文献Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
5HT2
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BU of 5ht2 by Molmil
Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex with 1-N6-etheno-adenine
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, DNA, ...
著者Schellenberg, M.J, Vilas, C.K, Williams, R.S.
登録日2016-01-26
公開日2016-04-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
4GZN
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BU of 4gzn by Molmil
Mouse ZFP57 zinc fingers in complex with methylated DNA
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Liu, Y, Zhang, X, Cheng, X.
登録日2012-09-06
公開日2012-10-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (0.99 Å)
主引用文献An atomic model of Zfp57 recognition of CpG methylation within a specific DNA sequence.
Genes Dev., 26, 2012
6YJB
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BU of 6yjb by Molmil
VcaM4I restriction endonuclease 5hmC-ssDNA complex
分子名称: CHLORIDE ION, DNA (5'-D(*CP*AP*(5HC)P*AP*G)-3'), GLYCEROL, ...
著者Pastor, M, Czapinska, H, Lutz, T, Helbrecht, I, Xu, S, Bochtler, M.
登録日2020-04-02
公開日2020-12-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA.
Nucleic Acids Res., 49, 2021
3IN5
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BU of 3in5 by Molmil
Structure of human DNA polymerase kappa inserting dATP opposite an 8-oxoG DNA lesion
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*C*CP*TP*AP*(8OG)P*GP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*G*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*(DOC))-3'), ...
著者Silverstein, T.D, Vasquez-Del Carpio, R, Aggarwal, A.K.
登録日2009-08-11
公開日2009-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of human DNA polymerase kappa inserting dATP opposite an 8-oxoG DNA lesion
PLOS ONE, 4, 2009
1QSY
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BU of 1qsy by Molmil
DDATP-Trapped closed ternary complex of the large fragment of DNA Polymerase I from thermus aquaticus
分子名称: 2',3'-dideoxyadenosine triphosphate, 5'-D(*AP*TP*TP*GP*CP*GP*CP*CP*TP*P*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3', ...
著者Li, Y, Mitaxov, V, Waksman, G.
登録日1999-06-24
公開日1999-08-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation.
Proc.Natl.Acad.Sci.USA, 96, 1999
8XVB
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BU of 8xvb by Molmil
Cryo-EM structure of ATP-DNA-MuB filaments
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent target DNA activator B, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
著者Zhao, X, Zhang, K, Li, S.
登録日2024-01-14
公開日2024-08-14
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Elucidating the Architectural dynamics of MuB filaments in bacteriophage Mu DNA transposition
Nat Commun, 15, 2024
5INN
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BU of 5inn by Molmil
Mouse Tdp2 D358N protein, apo state with increased disorder amongst variable DNA-binding grasp conformations
分子名称: CHLORIDE ION, GLYCEROL, SULFATE ION, ...
著者Schellenberg, M.J, Appel, C.D, Williams, R.S.
登録日2016-03-07
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
8E3D
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BU of 8e3d by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing CAST sequence (#11)
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*TP*TP*TP*GP*GP*GP*GP*AP*GP*GP*GP*GP*TP*CP*TP*TP*TP*AP*AP*CP*C)-3'), DNA (5'-D(P*GP*GP*TP*AP*AP*AP*AP*GP*AP*CP*CP*CP*CP*TP*CP*CP*CP*CP*AP*AP*AP*T)-3'), ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2022-08-17
公開日2023-02-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
7COC
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BU of 7coc by Molmil
Ternary complex of DNA polymerase Mu (K438A/Q441A) with 1-nt gapped DNA (T:dGMPNPP)
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ...
著者Guo, M, Zhao, Y.
登録日2020-08-04
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of genome instability mediated by human DNA polymerase mu misincorporation.
Nat Commun, 12, 2021
7COB
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BU of 7cob by Molmil
Ternary complex of DNA polymerase Mu (Q441A) with 1-nt gapped DNA (T:dGMPNPP)
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ...
著者Guo, M, Zhao, Y.
登録日2020-08-04
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.797 Å)
主引用文献Mechanism of genome instability mediated by human DNA polymerase mu misincorporation.
Nat Commun, 12, 2021
7CO6
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BU of 7co6 by Molmil
Binary complex of DNA polymerase Mu with 1-nt gapped DNA (templating thymine)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ...
著者Guo, M, Zhao, Y.
登録日2020-08-04
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of genome instability mediated by human DNA polymerase mu misincorporation.
Nat Commun, 12, 2021
7CO8
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BU of 7co8 by Molmil
Ternary complex of DNA polymerase Mu with 2-nt gapped DNA (T:dGMPNPP)
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ...
著者Guo, M, Zhao, Y.
登録日2020-08-04
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.697 Å)
主引用文献Mechanism of genome instability mediated by human DNA polymerase mu misincorporation.
Nat Commun, 12, 2021
7CO9
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BU of 7co9 by Molmil
Ternary complex of DNA polymerase Mu with 1-nt gapped DNA (T:dGMPNPP) and Mg
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ...
著者Guo, M, Zhao, Y.
登録日2020-08-04
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Mechanism of genome instability mediated by human DNA polymerase mu misincorporation.
Nat Commun, 12, 2021
7COD
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BU of 7cod by Molmil
Post insertion complex of DNA polymerase Mu (K438A/Q441A) with 1-nt gapped DNA
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*AP*G)-3'), ...
著者Guo, M, Zhao, Y.
登録日2020-08-04
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanism of genome instability mediated by human DNA polymerase mu misincorporation.
Nat Commun, 12, 2021
7COA
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BU of 7coa by Molmil
Ternary complex of DNA polymerase Mu with 1-nt gapped DNA (T:dGMPNPP) and Mn
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ...
著者Guo, M, Zhao, Y.
登録日2020-08-04
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Mechanism of genome instability mediated by human DNA polymerase mu misincorporation.
Nat Commun, 12, 2021
2FLD
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BU of 2fld by Molmil
I-MsoI Re-Designed for Altered DNA Cleavage Specificity
分子名称: 5'-D(*CP*GP*GP*AP*AP*CP*GP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*CP*TP*TP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*AP*AP*GP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*CP*GP*TP*TP*CP*CP*G)-3', CALCIUM ION, ...
著者Ashworth, J, Duarte, C.M, Havranek, J.J, Sussman, D, Monnat, R.J, Stoddard, B.L, Baker, D.
登録日2006-01-05
公開日2006-06-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Computational redesign of endonuclease DNA binding and cleavage specificity.
Nature, 441, 2006
7CUH
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BU of 7cuh by Molmil
Crystal structure of fission yeast Pot1 and ssDNA
分子名称: Protection of telomeres protein 1, Telomere single-strand DNA
著者Sun, H, Wu, Z, Wu, J, Lei, M.
登録日2020-08-23
公開日2021-08-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex.
Plos Genet., 18, 2022

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