PDB: 45459 件ウェブページステータス検索Chemie searchBIRD

---

5TRP	Crystal Structure of the Unliganded DH270 Cooperating Lineage Member DH272 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH272 Fab heavy chain, DH272 Fab light chain, ... 著者 Fera, D, Harrison, S.C. 登録日 2016-10-27 公開日 2017-03-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.692 Å) 主引用文献 Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Sci Transl Med, 9, 2017
7L8C	BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-3 from animal Rh.33104 (Wk26 time point) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ... 著者 Antanasijevic, A, Sewall, L.M, Perrett, H.R, Ward, A.B. 登録日 2020-12-31 公開日 2021-08-04 最終更新日 2021-08-25 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM. Nat Commun, 12, 2021
7XZR	Crystal structure of TNIK-AMPPNP-thiopeptide TP15 complex 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ... 著者 Hamada, K, Vinogradov, A.A, Zhang, Y, Chang, J.S, Nishimura, H, Goto, Y, Onaka, H, Suga, H, Ogata, K, Sengoku, T. 登録日 2022-06-03 公開日 2022-10-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 De Novo Discovery of Thiopeptide Pseudo-natural Products Acting as Potent and Selective TNIK Kinase Inhibitors. J.Am.Chem.Soc., 144, 2022
7L8A	BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-1 from animal Rh.33104 (Wk26 time point) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ... 著者 Antanasijevic, A, Sewall, L.M, Torrents de la Pena, A, Ward, A.B. 登録日 2020-12-31 公開日 2021-08-04 最終更新日 2021-08-25 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM. Nat Commun, 12, 2021
7L89	BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-4 from animal Rh.32034 (Wk26 time point) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ... 著者 Antanasijevic, A, Sewall, L.M, Rantalainen, K, Perrett, H.R, Ward, A.B. 登録日 2020-12-31 公開日 2021-08-04 最終更新日 2021-12-01 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM. Nat Commun, 12, 2021
7XZQ	Crystal structure of TNIK-thiopeptide TP1 complex 分子名称: 1,4-BUTANEDIOL, TRAF2 and NCK-interacting protein kinase, thiopeptide TP1 著者 Hamada, K, Vinogradov, A.A, Zhang, Y, Chang, J.S, Nishimura, H, Goto, Y, Onaka, H, Suga, H, Ogata, K, Sengoku, T. 登録日 2022-06-03 公開日 2022-10-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 De Novo Discovery of Thiopeptide Pseudo-natural Products Acting as Potent and Selective TNIK Kinase Inhibitors. J.Am.Chem.Soc., 144, 2022
7L86	BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-1 from animal Rh.32034 (Wk26 time point) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ... 著者 Antanasijevic, A, Sewall, L.M, Ward, A.B. 登録日 2020-12-31 公開日 2021-08-04 最終更新日 2021-11-24 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM. Nat Commun, 12, 2021
7LFA	Fab 3B6 bound to ApoL1 NTD 分子名称: Apolipoprotein L1, CHLORIDE ION, Fab 3B6 heavy chain, ... 著者 Ultsch, M, Kirchhofer, D. 登録日 2021-01-15 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.857 Å) 主引用文献 Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif. Commun Biol, 4, 2021
7L8D	BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-4 from animal Rh.33104 (Wk26 time point) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ... 著者 Antanasijevic, A, Sewall, L.M, Ward, A.B. 登録日 2020-12-31 公開日 2021-08-04 最終更新日 2021-08-25 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM. Nat Commun, 12, 2021
7YDG	Crystal structure of human SARS2 catalytic domain with a disease related mutation 分子名称: Serine--tRNA ligase, mitochondrial 著者 Wu, S, Li, P, Zhou, X.L, Fang, P. 登録日 2022-07-04 公開日 2022-11-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Selective degradation of tRNASer(AGY) is the primary driver for mitochondrial seryl-tRNA synthetase-related disease. Nucleic Acids Res., 50, 2022
7YDF	Crystal structure of human SARS2 catalytic domain 分子名称: Serine--tRNA ligase, mitochondrial 著者 Wu, S, Li, P, Zhou, X.L, Fang, P. 登録日 2022-07-04 公開日 2022-11-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Selective degradation of tRNASer(AGY) is the primary driver for mitochondrial seryl-tRNA synthetase-related disease. Nucleic Acids Res., 50, 2022
7L87	BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-2 from animal Rh.32034 (Wk26 time point) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ... 著者 Antanasijevic, A, Sewall, L.M, Yang, Y.R, Perrett, H.R, Ward, A.B. 登録日 2020-12-31 公開日 2021-08-04 最終更新日 2021-11-24 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM. Nat Commun, 12, 2021
7LGN	Cyanophycin synthetase 1 from T. morbirosei 分子名称: Cyanophycin synthase 著者 Sharon, I, Schmeing, T.M. 登録日 2021-01-20 公開日 2021-08-18 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structures and function of the amino acid polymerase cyanophycin synthetase. Nat.Chem.Biol., 17, 2021
5WMO	Crystal Structure of HLA-B7 in complex with RPP, an EBV peptide 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ... 著者 Gras, S, Rossjohn, J. 登録日 2017-07-30 公開日 2018-06-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses. J. Immunol., 200, 2018
7LHP	Crystal Structure of EcDsbA in a complex with methyl 2-(6-bromo-2-phenylbenzofuran-3-yl)acetate 分子名称: (6-bromo-2-phenyl-1-benzofuran-3-yl)acetic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA 著者 Ilyichova, O.V, Scanlon, M.J. 登録日 2021-01-26 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
5WOX	NMR solution structure of KanY protein (ms6282) using two 4D-spectra 分子名称: Uncharacterized protein 著者 Evangelidis, T, Nerli, S, Sgourakis, N.G, Tripsianes, K. 登録日 2017-08-03 公開日 2018-02-07 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Automated NMR resonance assignments and structure determination using a minimal set of 4D spectra. Nat Commun, 9, 2018
5WTD	Structure of human serum transferrin bound ruthenium at N-lobe 分子名称: FE (III) ION, MALONATE ION, RUTHENIUM ION, ... 著者 Sun, H, Wang, M, Lai, T.P, Zhang, H, Hao, Q. 登録日 2016-12-11 公開日 2017-12-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake. J.Inorg.Biochem., 234, 2022
5WOZ	NMR solution structure of Rtt103 (RTT) protein using two 4D-spectra 分子名称: Regulator of Ty1 transposition protein 103 著者 Evangelidis, T, Nerli, S, Sgourakis, N.G, Tripsianes, K. 登録日 2017-08-03 公開日 2018-02-07 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Automated NMR resonance assignments and structure determination using a minimal set of 4D spectra. Nat Commun, 9, 2018
7VHV	Crystal structure of S. aureus D-alanine alanyl carrier protein ligase 分子名称: ADENOSINE-5'-TRIPHOSPHATE, D-alanine--D-alanyl carrier protein ligase, MAGNESIUM ION 著者 Lee, B.J, Lee, I.-G, Im, H.G, Yoon, H.J. 登録日 2021-09-23 公開日 2022-04-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural and functional analysis of the D-alanyl carrier protein ligase DltA from Staphylococcus aureus Mu50. Acta Crystallogr D Struct Biol, 78, 2022
5U29	Crystal structure of Cryptococcus neoformans H99 Acetyl-CoA Synthetase in complex with Ac-AMS 分子名称: 1,2-ETHANEDIOL, 5'-O-(acetylsulfamoyl)adenosine, Acetyl-coenzyme A synthetase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID), Fox III, D, Edwards, T.E, Potts, K.T, Taylor, B.M. 登録日 2016-11-30 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of Cryptococcus neoformans H99 Acetyl-CoA Synthetase in complex with Ac-AMS To Be Published
7MI2	Seb1-G476S RNA binding domain 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Rpb7-binding protein seb1 著者 Jacewicz, A, Shuman, S. 登録日 2021-04-16 公開日 2021-07-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1. Proc.Natl.Acad.Sci.USA, 118, 2021
7VB2	Solution structure of human ribosomal protein uL11 分子名称: 60S ribosomal protein L12 著者 Lee, K.M, Wong, K.B. 登録日 2021-08-30 公開日 2022-04-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The flexible N-terminal motif of uL11 unique to eukaryotic ribosomes interacts with P-complex and facilitates protein translation. Nucleic Acids Res., 50, 2022
5WRM	Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y658 peptide 分子名称: AP-2 complex subunit mu, Insulin receptor substrate 1 著者 Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. 登録日 2016-12-02 公開日 2017-12-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.597 Å) 主引用文献 IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling Elife, 7, 2018
7LUF	HSV1 polymerase ternary complex with dsDNA and PNU-183792 分子名称: DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3'), DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3'), DNA polymerase, ... 著者 Hayes, R.P, Klein, D. 登録日 2021-02-22 公開日 2021-04-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase. Nat Commun, 12, 2021
5WBP	Structure of human Ketohexokinase complexed with hits from fragment screening 分子名称: 3-(trifluoromethyl)quinoxalin-2(1H)-one, GLYCEROL, Ketohexokinase, ... 著者 Pandit, J. 登録日 2017-06-29 公開日 2017-09-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK). J. Med. Chem., 60, 2017

<1626162716281629163016311632163316341635163616371638163916401641>