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2UWQ
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BU of 2uwq by Molmil
Solution structure of ASPP2 N-terminus
分子名称: APOPTOSIS-STIMULATING OF P53 PROTEIN 2
著者Tidow, H, Rutherford, T.J, Andreeva, A, Fersht, A.R.
登録日2007-03-22
公開日2007-07-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of ASPP2 N-terminal domain (N-ASPP2) reveals a ubiquitin-like fold.
J. Mol. Biol., 371, 2007
6R7F
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BU of 6r7f by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Faull, S.V, Lau, A.M.C, Martens, C, Ahdash, Z, Yebenes, H, Schmidt, C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A.
登録日2019-03-28
公開日2019-08-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (8.2 Å)
主引用文献Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
6R6H
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BU of 6r6h by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Morris, E.P, Faull, S.V, Lau, A.M.C, Politis, A, Beuron, F, Cronin, N.
登録日2019-03-27
公開日2019-08-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (8.4 Å)
主引用文献Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
2FHI
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BU of 2fhi by Molmil
SUBSTRATE ANALOG (IB2) COMPLEX WITH THE HIS 96 ASN SUBSTITUTION OF THE FRAGILE HISTIDINE TRIAD PROTEIN, FHIT
分子名称: FRAGILE HISTIDINE TRIAD PROTEIN, P1-P2-METHYLENE-P3-THIO-DIADENOSINE TRIPHOSPHATE
著者Pace, H.C, Garrison, P.N, Robinson, A.K, Barnes, L.D, Draganescu, A, Rosler, A, Blackburn, G.M, Siprashvili, Z, Croce, C.M, Heubner, K, Brenner, C.
登録日1998-04-01
公開日1998-06-17
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit.
Proc.Natl.Acad.Sci.USA, 95, 1998
2ROC
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BU of 2roc by Molmil
Solution structure of Mcl-1 Complexed with Puma
分子名称: Bcl-2-binding component 3, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
著者Day, C.L, Smits, C, Fan, F.C, Lee, E.F, Fairlie, W.D, Hinds, M.G.
登録日2008-03-17
公開日2008-07-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1
J.Mol.Biol., 380, 2008
2N06
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BU of 2n06 by Molmil
Mdmx-298
分子名称: 4-[[(4S,5R)-5-(4-chlorophenyl)-4-(3-methoxyphenyl)-2-(4-methoxy-2-propan-2-yloxy-phenyl)-4,5-dihydroimidazol-1-yl]carbonyl]piperazin-2-one, Protein Mdm4
著者Grace, C.R, Kriwacki, R.W.
登録日2015-03-04
公開日2016-01-27
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J.Mol.Biol., 428, 2016
2ROD
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BU of 2rod by Molmil
Solution Structure of MCL-1 Complexed with NoxaA
分子名称: Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, Noxa
著者Day, C.L, Smits, C, Fan, F.C, Lee, E.F, Fairlie, W.D, Hinds, M.G.
登録日2008-03-17
公開日2008-07-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1
J.Mol.Biol., 380, 2008
2KZU
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BU of 2kzu by Molmil
DAXX helical bundle (DHB) domain / Rassf1C complex
分子名称: Death-associated protein 6, Ras association (RalGDS/AF-6) domain family 1
著者Escobar-Cabrera, E, Lau, D.K.W, Giovinazzi, S, Ishov, A.M, McIntosh, L.P.
登録日2010-06-25
公開日2010-12-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Characterization of the DAXX N-Terminal Helical Bundle Domain and Its Complex with Rassf1C.
Structure, 18, 2010
2Y9U
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BU of 2y9u by Molmil
Structural basis of p63a SAM domain mutants involved in AEC syndrome
分子名称: SULFATE ION, TUMOR PROTEIN 63
著者Sathyamurthy, A, Freund, S.M.V, Johnson, C.M, Allen, M.D.
登録日2011-02-16
公開日2011-08-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Basis of P63Alpha Sam Domain Mutants Involved in Aec Syndrome.
FEBS J., 278, 2011
6V4E
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BU of 6v4e by Molmil
Crystal Structure Analysis of Zebra Fish MDM
分子名称: Protein Mdm4, Stapled peptide QSQQTF(0EH)NLWRLL(MK8)QN(NH2)
著者Seo, H.-S, Dhe-Paganon, S.
登録日2019-11-27
公開日2020-04-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Identification of a Structural Determinant for Selective Targeting of HDMX.
Structure, 28, 2020
6V4G
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BU of 6v4g by Molmil
Crystal Structure Analysis of Zebra fish MDMX
分子名称: Protein Mdm4, SULFATE ION, Stapled peptide QSQQTF(0EH)NLWRLE(MK8)QN(NH2)
著者Seo, H.-S, Dhe-Paganon, S.
登録日2019-11-27
公開日2020-04-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Identification of a Structural Determinant for Selective Targeting of HDMX.
Structure, 28, 2020
6V4H
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BU of 6v4h by Molmil
Crystal Structure Analysis of Zebra Fish MDMX
分子名称: Protein Mdm4, Stapled Peptide LSQETF(0EH)DLWKLL(MK8)EN(NH2)
著者Seo, H.-S, Dhe-Paganon, S.
登録日2019-11-27
公開日2020-04-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Identification of a Structural Determinant for Selective Targeting of HDMX.
Structure, 28, 2020
6V4F
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BU of 6v4f by Molmil
Crystal Structure Analysis of Zebra Fish MDMX
分子名称: Protein Mdm4, SULFATE ION, Stapled Peptide LSQETF(0EH)DLWKLE(MK8)EN(NH2)
著者Seo, H.-S, Dhe-Paganon, S.
登録日2019-11-27
公開日2020-04-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Identification of a Structural Determinant for Selective Targeting of HDMX.
Structure, 28, 2020
4G83
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BU of 4g83 by Molmil
Crystal Structure of p73 DNA-Binding Domain Tetramer bound to a Full Response-Element
分子名称: Tumor protein p73, ZINC ION, dna
著者Ethayathulla, A.S, Viadiu, H.
登録日2012-07-20
公開日2013-01-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal Structure of p73 DNA-Binding Domain Tetramer bound to a Full Response-Element
J.Biol.Chem., 2013
8INE
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BU of 8ine by Molmil
human nuclear pre-60S ribosomal particle - State G'
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Zhang, Y, Gao, N.
登録日2023-03-09
公開日2023-08-09
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Cell Res., 33, 2023
8INF
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BU of 8inf by Molmil
human nuclear pre-60S ribosomal particle - State F'
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Zhang, Y, Gao, N.
登録日2023-03-09
公開日2023-08-09
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Cell Res., 33, 2023
8FLB
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BU of 8flb by Molmil
Human nuclear pre-60S ribosomal subunit (State K2)
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Vanden Broeck, A, Klinge, S.
登録日2022-12-21
公開日2023-07-12
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Principles of human pre-60 S biogenesis.
Science, 381, 2023
8FLA
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BU of 8fla by Molmil
Human nuclear pre-60S ribosomal subunit (State K1)
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Vanden Broeck, A, Klinge, S.
登録日2022-12-21
公開日2023-07-12
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (2.63 Å)
主引用文献Principles of human pre-60 S biogenesis.
Science, 381, 2023
1TTV
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BU of 1ttv by Molmil
NMR Structure of a Complex Between MDM2 and a Small Molecule Inhibitor
分子名称: 1-{[4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]CARBONYL}PIPERAZINE, Ubiquitin-protein ligase E3 Mdm2
著者Fry, D.C, Emerson, S.D, Palme, S, Vu, B.T, Liu, C.M, Podlaski, F.
登録日2004-06-23
公開日2005-01-04
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure of a complex between MDM2 and a small molecule inhibitor.
J.Biomol.Nmr, 30, 2004
3VD0
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BU of 3vd0 by Molmil
structure of p73 DNA binding domain tetramer modulates p73 transactivation
分子名称: DNA (5'-D(*CP*AP*GP*GP*CP*AP*TP*GP*CP*CP*TP*G)-3'), Tumor protein p73, ZINC ION
著者Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H.
登録日2012-01-04
公開日2012-04-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure of p73 DNA-binding domain tetramer modulates p73 transactivation.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VD1
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BU of 3vd1 by Molmil
structure of p73 DNA binding domain tetramer modulates p73 transactivation
分子名称: DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), Tumor protein p73, ZINC ION
著者Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H.
登録日2012-01-04
公開日2012-04-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure of p73 DNA-binding domain tetramer modulates p73 transactivation.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VD2
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BU of 3vd2 by Molmil
structure of p73 DNA binding domain tetramer modulates p73 transactivation
分子名称: DNA (5'-D(*AP*TP*GP*GP*AP*CP*AP*TP*GP*TP*CP*CP*AP*T)-3'), Tumor protein p73, ZINC ION
著者Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H.
登録日2012-01-04
公開日2012-04-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure of p73 DNA-binding domain tetramer modulates p73 transactivation.
Proc.Natl.Acad.Sci.USA, 109, 2012
5KBD
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BU of 5kbd by Molmil
Structural Studies of Transcription Factor p73 DNA Binding Domain Bound to PA26 20-mer Response Element
分子名称: DNA (5'-D(P*AP*GP*AP*CP*TP*TP*GP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*CP*AP*AP*GP*TP*CP*T)-3'), Tumor protein p73, ...
著者Nguyen, H.T, Huang, D.
登録日2016-06-03
公開日2016-08-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Studies of Transcription Factor p73 DNA Binding Domain Bound to PA26 20-mer Response Element
To Be Published
2VYR
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BU of 2vyr by Molmil
Structure of human MDM4 N-terminal domain bound to a single domain antibody
分子名称: HUMAN SINGLE DOMAIN ANTIBODY, MDM4 PROTEIN, SULFATE ION
著者Yu, G.W, Vaysburd, M, Allen, M.D, Settanni, G, Fersht, A.R.
登録日2008-07-28
公開日2008-11-25
最終更新日2013-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of Human Mdm4 N-Terminal Domain Bound to a Single-Domain Antibody.
J.Mol.Biol., 385, 2009
5VK1
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BU of 5vk1 by Molmil
Crystal structure of human MDM4 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
分子名称: Lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI, Protein Mdm4
著者Tolbert, W.D, Gohain, N, Pazgier, M.
登録日2017-04-20
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
Chem Sci, 10, 2019

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