PDB: 239149 件ウェブページステータス検索Chemie searchBIRD

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3NZC	Structural Analysis of Pneumocystis carinii and Human DHFR Complexes with NADPH and a Series of Five Potent 5-(omega-carboxy(alkyloxy)pyrido[2,3-d]pyridine Derivativea 分子名称: 6-[2-methoxy-5-(2-phenylethoxy)benzyl]-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine, Dihydrofolate reductase, GLYCEROL, ... 著者 Cody, V. 登録日 2010-07-16 公開日 2010-12-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural analysis of Pneumocystis carinii and human DHFR complexes with NADPH and a series of five potent 6-[5'-([omega]-carboxyalkoxy)benzyl]pyrido[2,3-d]pyrimidine derivatives Acta Crystallogr.,Sect.D, 67, 2011
3NZB	Structural Analysis of Pneumocystis carinii and Human DHFR Complexes with NADPH and a Series of Potent 5-(omega-carboxyl(alkyloxy)pyrido[2,-d]pyrimidine Derivatives 分子名称: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ethyl 6-{3-[(2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-6-yl)methyl]-4-methoxyphenoxy}hexanoate 著者 Cody, V. 登録日 2010-07-16 公開日 2010-12-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structural analysis of Pneumocystis carinii and human DHFR complexes with NADPH and a series of five potent 6-[5'-([omega]-carboxyalkoxy)benzyl]pyrido[2,3-d]pyrimidine derivatives Acta Crystallogr.,Sect.D, 67, 2011
1TKF	Streptomyces griseus aminopeptidase complexed with D-tryptophan 分子名称: Aminopeptidase, CALCIUM ION, D-TRYPTOPHAN, ... 著者 Reiland, V, Gilboa, R, Spungin-Bialik, A, Schomburg, D, Shoham, Y, Blumberg, S, Shoham, G. 登録日 2004-06-08 公開日 2005-06-14 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Interactions of D Amino Acids with Streptomyces griseus Aminopeptidase To be Published
1DA2	MOLECULAR AND CRYSTAL STRUCTURE OF D(CGCGMO4CG): N4-METHOXYCYTOSINE/GUANINE BASE-PAIRS IN Z-DNA 分子名称: DNA (5'-D(*CP*GP*CP*GP*(C45)P*G)-3') 著者 Van Meervelt, L, Moore, M.H, Lin, P.K.T, Brown, D.M, Kennard, O. 登録日 1992-10-17 公開日 1993-07-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Molecular and crystal structure of d(CGCGmo4CG): N4-methoxycytosine.guanine base-pairs in Z-DNA. J.Mol.Biol., 216, 1990
4TWC	2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4- carboxamide derivatives as potent inhibitors of CK1d/e 分子名称: 2-{[2-(trifluoromethoxy)benzoyl]amino}-N-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1,3-thiazole-4-carboxamide, Casein kinase I isoform delta, DIMETHYL SULFOXIDE, ... 著者 Bischof, J, Leban, L, Zaja, M, Grothey, A, Radunsky, B, Othersen, O, Strobl, S, Vitt, D, Knippschild, U. 登録日 2014-06-30 公開日 2014-10-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4-carboxamide derivatives as potent inhibitors of CK1d/e. Amino Acids, 43, 2012
3T6C	Crystal structure of an enolase from pantoea ananatis (efi target efi-501676) with bound d-gluconate and mg 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, D-gluconic acid, ... 著者 Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Hillerich, B, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2011-07-28 公開日 2011-08-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.598 Å) 主引用文献 Crystal structure of an enolase from pantoea ananatis (efi target efi-501676) with bound d-gluconate and mg to be published
4HU2	Crystal structure of LdtMt2, a L,D-transpeptidase from Mycobacterium tuberculosis: domain A and B 分子名称: PROBABLE CONSERVED LIPOPROTEIN LPPS, SULFATE ION 著者 Both, D, Steiner, E, Lindqvist, Y, Schnell, R, Schneider, G. 登録日 2012-11-02 公開日 2012-12-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Structure of LdtMt2, an L,D-transpeptidase from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 69, 2013
4EKE	Crystal structure of GPb in complex with DK11 分子名称: 3-(beta-D-glucopyranosyl)-6-pentylfuro[2,3-d]pyrimidin-2(3H)-one, Glycogen phosphorylase, muscle form 著者 Kantsadi, A.L, Skamnaki, V.T, Leonidas, D.D. 登録日 2012-04-09 公開日 2012-07-25 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The binding of C5-alkynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: Synthesis, biochemical and biological assessment. Eur.J.Med.Chem., 54, 2012
296D	SEQUENCE-DEPENDENT EFFECTS IN DRUG-DNA INTERACTION: THE CRYSTAL STRUCTURE OF HOECHST 33258 BOUND TO THE D(CGCAAATTTGCG)2 DUPLEX 分子名称: 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3') 著者 Spink, N, Brown, D.G, Skelly, J.V, Neidle, S. 登録日 1994-07-21 公開日 1996-12-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Sequence-dependent effects in drug-DNA interaction: the crystal structure of Hoechst 33258 bound to the d(CGCAAATTTGCG)2 duplex. Nucleic Acids Res., 22, 1994
1HMA	THE SOLUTION STRUCTURE AND DYNAMICS OF THE DNA BINDING DOMAIN OF HMG-D FROM DROSOPHILA MELANOGASTER 分子名称: HMG-D 著者 Jones, D.N.M, Searles, M.A, Shaw, G.L, Churchill, M.E.A, Ner, S.S, Keeler, J, Travers, A.A, Neuhaus, D. 登録日 1994-05-12 公開日 1994-07-31 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The solution structure and dynamics of the DNA-binding domain of HMG-D from Drosophila melanogaster. Structure, 2, 1994
3PH3	Clostridium thermocellum Ribose-5-Phosphate Isomerase B with d-ribose 分子名称: D-ribose, Ribose-5-phosphate isomerase 著者 Jung, J, Kim, J.K, Yeom, S.J, Ahn, Y.J, Oh, D.K, Kang, L.W. 登録日 2010-11-03 公開日 2011-06-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Crystal structure of Clostridium thermocellum ribose-5-phosphate isomerase B reveals properties critical for fast enzyme kinetics. Appl.Microbiol.Biotechnol., 90, 2011
3G2L	Crystal structure of 1-(beta-D-glucopyranosyl)-4-substituted-1,2,3-triazoles in complex with glycogen phosphorylase 分子名称: 1-beta-D-glucopyranosyl-4-naphthalen-1-yl-1H-1,2,3-triazole, Glycogen phosphorylase, muscle form 著者 Chrysina, E.D, Bokor, E, Alexacou, K.-M, Charavgi, M.-D, Oikonomakos, G.N, Zographos, S.E, Leonidas, D.D, Oikonomakos, N.G, Somsak, L. 登録日 2009-01-31 公開日 2010-02-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Amide-1,2,3-triazole bioisosterism: the glycogen phosphorylase case Tetrahedron: Asymmetry, 20, 2009
4LNC	Neutron structure of the cyclic glucose bound Xylose Isomerase E186Q mutant 分子名称: MAGNESIUM ION, MANGANESE (II) ION, Xylose isomerase, ... 著者 Munshi, P, Meilleur, F, Myles, D. 登録日 2013-07-11 公開日 2014-02-12 最終更新日 2024-02-28 実験手法 NEUTRON DIFFRACTION (2.19 Å) 主引用文献 Neutron structure of the cyclic glucose-bound xylose isomerase E186Q mutant. Acta Crystallogr.,Sect.D, 70, 2014
3G2K	Crystal structure of 1-(beta-D-glucopyranosyl)-4-substituted-1,2,3-triazole 分子名称: 1-beta-D-glucopyranosyl-4-naphthalen-2-yl-1H-1,2,3-triazole, Glycogen phosphorylase, muscle form 著者 Chrysina, E.D, Bokor, E, Alexacou, K.-M, Charavgi, M.-D, Oikonomakos, G.N, Zographos, S.E, Leonidas, D.D, Oikonomakos, N.G, Somsak, L. 登録日 2009-01-31 公開日 2010-02-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Amide-1,2,3-triazole bioisosterism: the glycogen phosphorylase case Tetrahedron: Asymmetry, 20, 2009
3CWB	Chicken Cytochrome BC1 Complex inhibited by an iodinated analogue of the polyketide Crocacin-D 分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, AZIDE ION, CARDIOLIPIN, ... 著者 Huang, L, Cromartie, T, Viner, R, Crowley, P.J, Berry, E.A. 登録日 2008-04-21 公開日 2008-08-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.51 Å) 主引用文献 The role of molecular modeling in the design of analogues of the fungicidal natural products crocacins A and D. Bioorg.Med.Chem., 16, 2008
1EP0	HIGH RESOLUTION CRYSTAL STRUCTURE OF DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE FROM METHANOBACTERIUM THERMOAUTOTROPHICUM 分子名称: DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE 著者 Christendat, D, Saridakis, V, Bochkarev, A, Pai, E.F, Arrowsmith, C.H, Edwards, A.M, Northeast Structural Genomics Consortium (NESG) 登録日 2000-03-24 公開日 2000-12-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of dTDP-4-keto-6-deoxy-D-hexulose 3,5-epimerase from Methanobacterium thermoautotrophicum complexed with dTDP. J.Biol.Chem., 275, 2000
1DN4	SOLVATION OF THE LEFT-HANDED HEXAMER D(5BRC-G-5BRC-G-5BRC-G) IN CRYSTALS GROWN AT TWO TEMPERATURES 分子名称: DNA (5'-D(*(CBR)P*GP*(CBR)P*GP*(CBR)P*G)-3') 著者 Chevrier, B, Dock, A.C, Hartmann, B, Leng, M, Moras, D, Thuong, M.T, Westhof, E. 登録日 1986-12-01 公開日 1987-04-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Solvation of the left-handed hexamer d(5BrC-G-5BrC-G-5 BrC-G) in crystals grown at two temperatures. J.Mol.Biol., 188, 1986
4AUN	Crystal structure, recombinant expression and mutagenesis studies of the bifunctional catalase-phenol oxidase from Scytalidium thermophilum 分子名称: CALCIUM ION, CATALASE-PHENOL OXIDASE, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE 著者 Yuzugullu, Y, Trinh, C.H, Smith, M.A, Pearson, A.R, Phillips, S.E.V, Sutay Kocabas, D, Bakir, U, Ogel, Z.B, McPherson, M.J. 登録日 2012-05-18 公開日 2013-02-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structure, Recombinant Expression and Mutagenesis Studies of the Catalase with Oxidase Activity from Scytalidium Thermophilum Acta Crystallogr.,Sect.D, 69, 2013
1DN5	SOLVATION OF THE LEFT-HANDED HEXAMER D(5BRC-G-5BRC-G-5BRC-G) IN CRYSTALS GROWN AT TWO TEMPERATURES 分子名称: DNA (5'-D(*(CBR)P*GP*(CBR)P*GP*(CBR)P*G)-3') 著者 Chevrier, B, Dock, A.C, Hartmann, B, Leng, M, Moras, D, Thuong, M.T, Westhof, E. 登録日 1986-12-01 公開日 1987-04-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Solvation of the left-handed hexamer d(5BrC-G-5BrC-G-5 BrC-G) in crystals grown at two temperatures. J.Mol.Biol., 188, 1986
2XW9	Crystal Structure of Complement Factor D mutant S183A 分子名称: COMPLEMENT FACTOR D, GLYCEROL 著者 Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P. 登録日 2010-11-01 公開日 2011-01-12 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation. Science, 330, 2010
1DA0	DNA-DRUG INTERACTIONS: THE CRYSTAL STRUCTURE OF D(CGATCG) COMPLEXED WITH DAUNOMYCIN 分子名称: DAUNOMYCIN, DNA (5'-D(*CP*GP*AP*TP*CP*G)-3') 著者 Moore, M.H, Hunter, W.N, Langlois D'Estaintot, B, Kennard, O. 登録日 1992-10-17 公開日 1993-07-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 DNA-drug interactions. The crystal structure of d(CGATCG) complexed with daunomycin. J.Mol.Biol., 206, 1989
2Y68	Structure-based design of a new series of D-glutamic acid-based inhibitors of bacterial MurD ligase 分子名称: 2-[[2-fluoro-5-[[[4-[(Z)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenyl]amino]methyl]phenyl]carbonylamino]pentanedioic acid, AZIDE ION, CHLORIDE ION, ... 著者 Tomasic, T, Zidar, N, Sink, R, Kovac, A, Patin, D, Blanot, D, Contreras-Martel, C, Dessen, A, Muller-Premru, M, Zega, A, Gobec, S, Peterlin-Masic, L, Kikelj, D. 登録日 2011-01-20 公開日 2011-06-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD). J. Med. Chem., 54, 2011
7DZ5	Crystal structures of D-allulose 3-epimerase with D-sorbose from Sinorhizobium fredii 分子名称: D-sorbose, D-tagatose 3-epimerase, MAGNESIUM ION, ... 著者 Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M. 登録日 2021-01-23 公開日 2022-08-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening Angew.Chem.Int.Ed.Engl., 2023
3IKP	Crystal structure of inositol phosphate bound trimeric human lung surfactant protein D 分子名称: CALCIUM ION, D-MYO-INOSITOL-1-PHOSPHATE, Pulmonary surfactant-associated protein D 著者 Shrive, A.K, Greenhough, T.J. 登録日 2009-08-06 公開日 2009-11-17 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural characterisation of ligand-binding determinants in human lung surfactant protein D: influence of Asp325 J.Mol.Biol., 394, 2009
4EL0	Crystal structure of GPb in complex with DK16 分子名称: 3-(beta-D-glucopyranosyl)-6-propylfuro[2,3-d]pyrimidin-2(3H)-one, Glycogen phosphorylase, muscle form 著者 Kantsadi, A.L, Skamnaki, V.T, Leonidas, D.D. 登録日 2012-04-10 公開日 2012-07-25 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The binding of C5-alkynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: Synthesis, biochemical and biological assessment. Eur.J.Med.Chem., 54, 2012

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