PDB: 752 件ウェブページステータス検索Chemie searchBIRD

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8UTR	KIF1A[1-393] ADP bound in complex with a microtubule 分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. 登録日 2023-10-31 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
8U3Z	Model of TTLL6 bound to microtubule from composite map 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Mahalingan, K.K, Grotjahn, D, Li, Y, Lander, G.C, Zehr, E.A, Roll-Mecak, A. 登録日 2023-09-08 公開日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis for alpha-tubulin-specific and modification state-dependent glutamylation. Nat.Chem.Biol., 2024
8UTW	KIF1A[1-393] P305L mutant APO in complex with a microtubule 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... 著者 Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. 登録日 2023-10-31 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
8UTS	KIF1A[1-393] APO in complex with a microtubule 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... 著者 Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. 登録日 2023-10-31 公開日 2024-06-12 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
8UTV	KIF1A[1-393] P305L mutant ADP bound in complex with a microtubule 分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. 登録日 2023-10-31 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
8UTN	KIF1A[1-393] AMP-PNP bound two-heads-bound state in complex with a microtubule (class T23L1) 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... 著者 Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. 登録日 2023-10-31 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
8UTY	KIF1A[1-393] P364L mutant AMP-PNP bound two-heads-bound state in complex with a microtubule 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... 著者 Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. 登録日 2023-10-31 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
8UTP	KIF1A[1-393] - AMP-PNP two-heads-bound state in complex with a microtubule - class T3L1 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... 著者 Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. 登録日 2023-10-31 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
8UTU	KIF1A[1-393] P305L mutant AMP-PNP bound one and two heads bound states merged, in complex with a microtubule 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... 著者 Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. 登録日 2023-10-31 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
8UTQ	KIF1A[1-393] AMP-PNP bound one-head-bound state in complex with a microtubule - class T1L02* 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... 著者 Benoit, M.P.M.H, Rao, L, Asenjo, A.B, Gennerich, A, Sosa, H. 登録日 2023-10-31 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM of human KIF1A reveals its mechanism of motility and the effect of its pathogenic variant P305L To Be Published
8SF7	48-nm doublet microtubule from Tetrahymena thermophila strain MEC17 分子名称: CFAM166A, CFAM166B, CFAM166C, ... 著者 Black, C.S, Kubo, S, Yang, S.K, Bui, K.H. 登録日 2023-04-10 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Effect of alpha-tubulin acetylation on the doublet microtubule structure. Elife, 12, 2024
8VT7	Structure of the gamma tubulin ring complex nucleated microtubule protofilament. 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Aher, A, Urnavicius, L, Kapoor, T.M. 登録日 2024-01-25 公開日 2024-03-27 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 Structure of the gamma-tubulin ring complex-capped microtubule. Nat.Struct.Mol.Biol., 2024
7TUB	The beta-tubulin folding intermediate IV 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... 著者 Zhao, Y, Frydman, J, Chiu, W. 登録日 2022-02-02 公開日 2022-12-28 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
7TRG	The beta-tubulin folding intermediate I 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... 著者 Zhao, Y, Frydman, J, Chiu, W. 登録日 2022-01-28 公開日 2022-12-28 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
7TTN	The beta-tubulin folding intermediate II 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... 著者 Zhao, Y, Frydman, J, Chiu, W. 登録日 2022-02-01 公開日 2022-12-28 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
7TTT	The beta-tubulin folding intermediate III 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... 著者 Zhao, Y, Frydman, J, Chiu, W. 登録日 2022-02-01 公開日 2022-12-28 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
7TTD	Tubulin-RB3_SLD in complex with compound 12e 分子名称: 7-methoxy-4-[2-(morpholin-4-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-3,4-dihydroquinoxalin-2(1H)-one, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 White, S.W, Yun, M. 登録日 2022-02-01 公開日 2023-04-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo. Acs Pharmacol Transl Sci, 6, 2023
7TTF	Tubulin-RB3_SLD in complex with compound 12k 分子名称: 7-methoxy-4-[2-(methylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-3,4-dihydroquinoxalin-2(1H)-one, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... 著者 White, S.W, Yun, M. 登録日 2022-02-01 公開日 2023-04-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo. Acs Pharmacol Transl Sci, 6, 2023
7TTE	Tubulin-RB3_SLD in complex with compound 12j 分子名称: 4-[2-(cyclopropylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 White, S.W, Yun, M. 登録日 2022-02-01 公開日 2023-04-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo. Acs Pharmacol Transl Sci, 6, 2023
3J1T	High affinity dynein microtubule binding domain - tubulin complex 分子名称: Cytoplasmic dynein 1 heavy chain 1, seryl t-RNA synthetase chimera, Tubulin alpha-1B chain, ... 著者 Redwine, W.B, Hernandez-Lopez, R, Zou, S, Huang, J, Reck-Peterson, S.L, Leschziner, A.E. 登録日 2012-06-25 公開日 2012-09-26 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (9.7 Å) 主引用文献 Structural basis for microtubule binding and release by dynein. Science, 337, 2012
3J6E	Energy minimized average structure of Microtubules stabilized by GmpCpp 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... 著者 Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. 登録日 2014-02-18 公開日 2014-06-04 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis. Cell(Cambridge,Mass.), 157, 2014
3J6F	Minimized average structure of GDP-bound dynamic microtubules 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. 登録日 2014-02-19 公開日 2014-06-04 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis. Cell(Cambridge,Mass.), 157, 2014
3J8X	High-resolution structure of no-nucleotide kinesin on microtubules 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... 著者 Shang, Z, Zhou, K, Xu, C, Csencsits, R, Cochran, J.C, Sindelar, C.V. 登録日 2014-11-20 公開日 2014-12-10 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation. Elife, 3, 2014
3JAK	Cryo-EM structure of GTPgammaS-microtubule co-polymerized with EB3 (merged dataset with and without kinesin bound) 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Zhang, R, Nogales, E. 登録日 2015-06-16 公開日 2015-08-12 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins. Cell(Cambridge,Mass.), 162, 2015
7VMJ	Crystal structure of tubulin with 17a 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... 著者 Jifa, Z, Lun, T. 登録日 2021-10-08 公開日 2022-10-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of tubulin with 17j To Be Published

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