PDB: 496 件ウェブページステータス検索Chemie searchBIRD

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4LMN	Crystal Structure of MEK1 kinase bound to GDC0973 分子名称: Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Ultsch, M.H. 登録日 2013-07-10 公開日 2013-08-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers. Nature, 501, 2013
4IZA	Structure of Dually Phosphorylated ERK2 bound to the PEA-15 Death Effector Domain 分子名称: Astrocytic phosphoprotein PEA-15, Mitogen-activated protein kinase 1 著者 Mace, P.D, Robinson, H, Riedl, S.J. 登録日 2013-01-29 公開日 2013-04-10 最終更新日 2013-04-24 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK. Nat Commun, 4, 2013
4IZ7	Structure of Non-Phosphorylated ERK2 bound to the PEA-15 Death Effector Domain 分子名称: Astrocytic phosphoprotein PEA-15, Mitogen-activated protein kinase 1, SODIUM ION 著者 Mace, P.D, Robinson, H, Riedl, S.J. 登録日 2013-01-29 公開日 2013-04-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK. Nat Commun, 4, 2013
4IZ5	Structure of the complex between ERK2 phosphomimetic mutant and PEA-15 分子名称: ADENOSINE-5'-DIPHOSPHATE, Astrocytic phosphoprotein PEA-15, Mitogen-activated protein kinase 1, ... 著者 Mace, P.D, Robinson, H, Riedl, S.J. 登録日 2013-01-29 公開日 2013-04-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK. Nat Commun, 4, 2013
4I5H	Crystal Structure of a Double Mutant Rat Erk2 Complexed With a Type II Quinazoline Inhibitor 分子名称: Mitogen-activated protein kinase 1, N-{3-[2-(cyclopropylamino)quinazolin-6-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide 著者 Hari, S.B, Maly, D.J, Merritt, E.A. 登録日 2012-11-28 公開日 2013-07-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Sequence determinants of a specific inactive protein kinase conformation. Chem.Biol., 20, 2013
4H3Q	Crystal structure of human ERK2 complexed with a MAPK docking peptide 分子名称: Dual specificity mitogen-activated protein kinase kinase 2, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Gogl, G, Toeroe, I, Remenyi, A. 登録日 2012-09-14 公開日 2013-02-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Protein-peptide complex crystallization: a case study on the ERK2 mitogen-activated protein kinase Acta Crystallogr.,Sect.D, 69, 2013
4H3P	Crystal structure of human ERK2 complexed with a MAPK docking peptide 分子名称: Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-1 著者 Gogl, G, Toeroe, I, Remenyi, A. 登録日 2012-09-14 公開日 2013-02-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Protein-peptide complex crystallization: a case study on the ERK2 mitogen-activated protein kinase Acta Crystallogr.,Sect.D, 69, 2013
4GVA	ADP-bound form of the ERK2 kinase 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Mitogen-activated protein kinase 1 著者 Pozharski, E, Zhang, J, Shapiro, P. 登録日 2012-08-30 公開日 2012-09-12 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 ADP-bound form of the ERK2 kinase TO BE PUBLISHED
4GT3	ATP-bound form of the ERK2 kinase 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Pozharski, E, Zhang, J, Shapiro, P. 登録日 2012-08-28 公開日 2012-09-12 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 ATP-bound form of the ERK2 kinase TO BE PUBLISHED
4GSB	Monoclinic crystal form of the apo-ERK2 分子名称: GLYCEROL, Mitogen-activated protein kinase 1, SULFATE ION, ... 著者 Pozharski, E, Zhang, J, Shapiro, P. 登録日 2012-08-27 公開日 2012-09-12 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Monoclinic crystal form of the apo-ERK2 TO BE PUBLISHED
4G6O	Crystal Structure of the ERK2 分子名称: 1,2-ETHANEDIOL, 4-{4-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl}-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1H-pyrrole-2-carboxamide, Mitogen-activated protein kinase 1, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-07-19 公開日 2012-09-19 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the ERK2 complexed with E28 to be published
4G6N	Crystal Structure of the ERK2 分子名称: 3-(4-chlorophenyl)-4,5,6,7-tetrahydro-1H-indazole, Mitogen-activated protein kinase 1, SULFATE ION 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-07-19 公開日 2012-09-19 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the ERK2 complexed with EK0 to be published
4FV9	Crystal Structure of the ERK2 complexed with E71 分子名称: 1,2-ETHANEDIOL, 3-[4-(2,3-difluorophenyl)-1,2-oxazol-5-yl]-5-(pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine, Mitogen-activated protein kinase 1, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-29 公開日 2012-08-29 最終更新日 2014-09-24 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Crystal Structure of the ERK2 complexed with E71 TO BE PUBLISHED
4FV8	Crystal Structure of the ERK2 complexed with E63 分子名称: 1,2-ETHANEDIOL, 6-({4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]-5-(phenylamino)pyrimidin-2-yl}amino)-1,2-dihydro-3H-indazol-3-one, Mitogen-activated protein kinase 1, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-29 公開日 2012-08-29 最終更新日 2014-09-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the ERK2 complexed with E63 TO BE PUBLISHED
4FV7	Crystal Structure of the ERK2 complexed with E94 分子名称: 1,2-ETHANEDIOL, 4-(3-chlorophenyl)-5-{2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}-2-{[2-(piperidin-1-yl)ethyl]amino}thiophene-3-carbonitrile, GLYCEROL, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-29 公開日 2012-08-29 最終更新日 2014-09-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of the ERK2 complexed with E94 TO BE PUBLISHED
4FV6	Crystal Structure of the ERK2 complexed with E57 分子名称: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-4-(2-{[(2S)-1-hydroxybutan-2-yl]amino}-5-methylpyrimidin-4-yl)-1H-pyrrole-2-carboxamide, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-29 公開日 2012-08-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of the ERK2 complexed with E57 TO BE PUBLISHED
4FV5	Crystal Structure of the ERK2 complexed with EK9 分子名称: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, N-[(1S)-2-hydroxy-1-phenylethyl]-4-(5-methyl-2-phenylpyrimidin-4-yl)-1H-pyrrole-2-carboxamide, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-29 公開日 2012-08-29 最終更新日 2014-09-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the ERK2 complexed with EK9 TO BE PUBLISHED
4FV4	Crystal Structure of the ERK2 complexed with EK7 分子名称: 9-(dimethylamino)-2-[(3-hydroxyphenyl)amino]-5,6-dihydrothieno[3,4-h]quinazoline-7-carbonitrile, GLYCEROL, Mitogen-activated protein kinase 1, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-29 公開日 2012-08-29 最終更新日 2014-09-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of the ERK2 complexed with EK7 TO BE PUBLISHED
4FV3	Crystal Structure of the ERK2 complexed with EK6 分子名称: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-29 公開日 2012-08-29 最終更新日 2014-09-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the ERK2 complexed with EK6 TO BE PUBLISHED
4FV2	Crystal Structure of the ERK2 complexed with EK5 分子名称: 1,2-ETHANEDIOL, 4-[4-(3-chlorophenyl)-1H-pyrazol-5-yl]-N-(2,3-dihydro-1-benzofuran-5-ylmethyl)-1H-pyrrole-2-carboxamide, GLYCEROL, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-29 公開日 2012-08-29 最終更新日 2014-09-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the ERK2 complexed with EK5 TO BE PUBLISHED
4FV1	Crystal Structure of the ERK2 complexed with EK4 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Mitogen-activated protein kinase 1, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-28 公開日 2012-08-22 最終更新日 2014-09-24 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Crystal Structure of the ERK2 complexed with EK4 TO BE PUBLISHED
4FV0	Crystal Structure of the ERK2 complexed with EK3 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Mitogen-activated protein kinase 1, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-28 公開日 2012-08-22 最終更新日 2014-09-24 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of the ERK2 complexed with EK3 TO BE PUBLISHED
4FUY	Crystal Structure of the ERK2 complexed with EK2 分子名称: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-28 公開日 2012-08-22 最終更新日 2014-09-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the ERK2 complexed with EK2 TO BE PUBLISHED
4FUX	Crystal Structure of the ERK2 complexed with E75 分子名称: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Xie, X. 登録日 2012-06-28 公開日 2012-08-22 最終更新日 2014-09-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the ERK2 complexed with E75 TO BE PUBLISHED
4FMQ	Crystal structure of human ERK2 complexed with a MAPK docking peptide 分子名称: MAPK DOCKING PEPTIDE, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Gogl, G, Toeroe, I, Remenyi, A. 登録日 2012-06-18 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.098 Å) 主引用文献 Specificity of linear motifs that bind to a common mitogen-activated protein kinase docking groove. Sci.Signal., 5, 2012

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