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3OBJ
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Conformational plasticity of p38 MAP kinase DFG mutants in response to inhibitor binding
分子名称: 1-(5-TERT-BUTYL-2-METHYL-2H-PYRAZOL-3-YL)-3-(4-CHLORO-PHENYL)-UREA, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
著者Namboodiri, H.V, Karpusas, M, Bukhtiyarova, M, Springman, E.B.
登録日2010-08-06
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding
To be Published
2IJH
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Crystal structure analysis of ColE1 ROM mutant F14W
分子名称: Regulatory protein rop
著者Ladner, J.E.
登録日2006-09-29
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献New crystal structures of ColE1 Rom and variants resulting from mutation of a surface exposed residue: Implications for RNA-recognition.
Proteins, 72, 2008
2IJJ
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Crystal structure analysis of ColE1 ROM mutant F14Y
分子名称: Regulatory protein rop
著者Ladner, J.E.
登録日2006-09-29
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献New crystal structures of ColE1 Rom and variants resulting from mutation of a surface exposed residue: Implications for RNA-recognition.
Proteins, 72, 2008
2IJK
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Structure of a Rom protein dimer at 1.55 angstrom resolution
分子名称: Regulatory protein rop
著者Struble, E.B.
登録日2006-09-29
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献New crystal structures of ColE1 Rom and variants resulting from mutation of a surface exposed residue: Implications for RNA-recognition.
Proteins, 72, 2008
2IMD
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BU of 2imd by Molmil
Structure of SeMet 2-hydroxychromene-2-carboxylate isomerase (HCCA isomerase)
分子名称: (2S)-2-HYDROXY-2H-CHROMENE-2-CARBOXYLIC ACID, (3E)-4-(2-HYDROXYPHENYL)-2-OXOBUT-3-ENOIC ACID, 2-hydroxychromene-2-carboxylate isomerase, ...
著者Thompson, L.C, Ladner, J.E, Codreanu, S.G, Harp, J, Gilliland, G.L, Armstrong, R.N.
登録日2006-10-04
公開日2007-06-12
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献2-Hydroxychromene-2-carboxylic Acid Isomerase: A Kappa Class Glutathione Transferase from Pseudomonas putida
Biochemistry, 46, 2007
2IJI
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Structure of F14H mutant of ColE1 Rom protein
分子名称: Regulatory protein rop
著者Struble, E.B.
登録日2006-09-29
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献New crystal structures of ColE1 Rom and variants resulting from mutation of a surface exposed residue: Implications for RNA-recognition.
Proteins, 72, 2008
2IP2
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BU of 2ip2 by Molmil
Structure of the Pyocyanin Biosynthetic Protein PhzM
分子名称: Probable phenazine-specific methyltransferase
著者Ladner, J.E, Parsons, J.F, Robinson, H, Shi, K.
登録日2006-10-11
公開日2006-10-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and functional analysis of the pyocyanin biosynthetic protein PhzM from Pseudomonas aeruginosa.
Biochemistry, 46, 2007
6CX8
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Crystal structure of spermidine/spermine N-acetyltransferase SpeG from Vibrio cholerae in complex with manganese ions.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ISOPROPYL ALCOHOL, MANGANESE (II) ION, ...
著者Filippova, E.V, Minasov, G, Kiryukhina, O, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-04-02
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal structure of spermidine/spermine N-acetyltransferase SpeG from Vibrio cholerae in complex with manganese ions.
To Be Published
2GZ1
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Structure of Aspartate Semialdehyde Dehydrogenase (ASADH) from Streptococcus pneumoniae complexed with NADP
分子名称: Aspartate beta-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Faehnle, C.R, Le Coq, J, Liu, X, Viola, R.E.
登録日2006-05-10
公開日2006-08-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria.
J.Biol.Chem., 281, 2006
6D72
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Crystal structure of spermidine/spermine N-acetyltransferase SpeG from Yersinia pestis in complex with calcium ions.
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, MALONATE ION, ...
著者Filippova, E.V, Minasov, G, Kiryukhina, O, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-04-23
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Crystal structure of spermidine/spermine N-acetyltransferase SpeG from Yersinia pestis in complex with calcium ions.
To Be Published
2GZ2
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Structure of Aspartate Semialdehyde Dehydrogenase (ASADH) from Streptococcus pneumoniae complexed with 2',5'-ADP
分子名称: ADENOSINE-2'-5'-DIPHOSPHATE, Aspartate beta-semialdehyde dehydrogenase
著者Faehnle, C.R, Le Coq, J, Liu, X, Viola, R.E.
登録日2006-05-10
公開日2006-08-15
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria.
J.Biol.Chem., 281, 2006
6ANL
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BU of 6anl by Molmil
Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
分子名称: Mitogen-activated protein kinase 14, TAK-715
著者Snell, G.P, Okada, K, Bragstad, K, Sang, B.-C.
登録日2017-08-14
公開日2018-01-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors.
Bioorg. Med. Chem., 26, 2018
2GYY
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BU of 2gyy by Molmil
Structure of aspartate semialdehyde dehydrogenase (ASADH) from Streptococcus pneumoniae
分子名称: Aspartate beta-semialdehyde dehydrogenase
著者Faehnle, C.R, Le Coq, J, Liu, X, Viola, R.E.
登録日2006-05-10
公開日2006-08-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria.
J.Biol.Chem., 281, 2006
6DAU
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BU of 6dau by Molmil
Crystal structure of E33Q and E41Q mutant forms of the spermidine/spermine N-acetyltransferase SpeG from Vibrio cholerae
分子名称: GLYCEROL, Spermidine N1-acetyltransferase
著者Filippova, E.V, Minasov, G, Beahan, A, Kulyavtsev, P, Tan, L, Tran, D, Kuhn, M.L, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-05-02
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal structure of E33Q and E41Q mutant forms of the spermidine/spermine N-acetyltransferase SpeG from Vibrio cholerae.
To be Published
2XTH
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BU of 2xth by Molmil
K2PtBr6 binding to lysozyme
分子名称: HEXABROMOPLATINATE(IV), LYSOZYME C
著者Helliwell, J.R, Bell, A.M.T, Bryant, P, Fisher, S, Habash, J, Helliwell, M, Margiolaki, I, Kaenket, S, Watier, Y, Wright, J, Yalamanchili, S.K.
登録日2010-10-07
公開日2010-12-08
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Time-Dependent Analysis of K2Ptbr6 Binding to Lysozyme Studied by Protein Powder and Single Crystal X-Ray Analysis
Z.Kristallogr., 225, 2010
2HWV
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Crystal structure of an essential response regulator DNA binding domain, VicRc in Enterococcus faecalis, a member of the YycF subfamily.
分子名称: DNA-binding response regulator VicR, SULFATE ION
著者Trinh, C.H, Liu, Y, Phillips, S.E.V, Phillips-Jones, M.K.
登録日2006-08-02
公開日2007-01-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the response regulator VicR DNA-binding domain.
Acta Crystallogr.,Sect.D, 63, 2007
1M94
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BU of 1m94 by Molmil
Solution Structure of the Yeast Ubiquitin-Like Modifier Protein Hub1
分子名称: Protein YNR032c-a
著者Ramelot, T.A, Cort, J.R, Yee, A.A, Semesi, A, Edwards, A.M, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
登録日2002-07-26
公開日2002-12-11
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of the Yeast Ubiquitin-Like Modifier Protein Hub1
J.STRUCT.FUNCT.GENOM., 4, 2003
3VI0
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BU of 3vi0 by Molmil
Crystal structure of the O intermediate of the L93A mutant of bacteriorhodopsin
分子名称: 2,3-DI-PHYTANYL-GLYCEROL, 3-O-sulfo-beta-D-galactopyranose-(1-6)-alpha-D-mannopyranose-(1-2)-alpha-D-glucopyranose, Bacteriorhodopsin, ...
著者Kouyama, T, Zhang, J.
登録日2011-09-13
公開日2012-06-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the O intermediate of the Leu93Ala mutant of bacteriorhodopsin
Proteins, 80, 2012
3WIP
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BU of 3wip by Molmil
Crystal structure of acetylcholine bound to Ls-AChBP
分子名称: ACETATE ION, ACETYLCHOLINE, Acetylcholine-binding protein, ...
著者Olsen, J.A, Balle, T, Gajhede, M, Ahring, P.K, Kastrup, J.S.
登録日2013-09-24
公開日2014-04-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors
Plos One, 9, 2014
3ZGF
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Crystal structure of the Fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with in complex with NPE caged UDP-Gal (P2(1)2(1)2(1) space group)
分子名称: 1-(2-NITROPHENYL)ETHYL UDP-GALACTOSE, HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE, MANGANESE (II) ION, ...
著者Jorgensen, R, Batot, G.O, Hindsgaul, O, Tanaka, H, Perez, S, Imberty, A, Breton, C, Royant, A, Palcic, M.M.
登録日2012-12-17
公開日2013-01-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Structures of a Human Blood Group Glycosyltransferase in Complex with a Photo-Activatable Udp-Gal Derivative Reveal Two Different Binding Conformations
Acta Crystallogr.,Sect.F, 70, 2014
3ZH6
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The structure of Haemophilus influenzae Se_Met form of protein E
分子名称: PROTEIN E
著者Singh, B, Al-Jubair, T, Riesbeck, K, Thunnissen, M.M.G.M.
登録日2012-12-20
公開日2013-03-20
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (2.292 Å)
主引用文献The Unique Structure of Haemophilus Influenzae Protein E Reveals Multiple Binding Sites for Host Factors.
Infect.Immun., 81, 2013
3ZDG
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Crystal Structure of Ls-AChBP complexed with carbamoylcholine analogue 3-(dimethylamino)butyl dimethylcarbamate (DMABC)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(dimethylamino)butyl dimethylcarbamate, ACETYLCHOLINE BINDING PROTEIN, ...
著者Ussing, C.A, Hansen, C.P, Petersen, J.G, Jensen, A.A, Rohde, L.A.H, Ahring, P.K, Nielsen, E.O, Kastrup, J.S, Gajhede, M, Frolund, B, Balle, T.
登録日2012-11-26
公開日2013-02-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Synthesis, Pharmacology, and Biostructural Characterization of Novel Alpha(4)Beta(2) Nicotinic Acetylcholine Receptor Agonists.
J.Med.Chem., 56, 2013
3ZSJ
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Crystal structure of Human Galectin-3 CRD in complex with Lactose at 0.86 angstrom resolution
分子名称: GALECTIN-3, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Saraboji, K, Hakansson, M, Diehl, C, Nilsson, U.J, Leffler, H, Akke, M, Logan, D.T.
登録日2011-06-28
公開日2011-12-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (0.86 Å)
主引用文献The Carbohydrate-Binding Site in Galectin-3 is Pre-Organized to Recognize a Sugar-Like Framework of Oxygens: Ultra-High Resolution Structures and Water Dynamics.
Biochemistry, 51, 2012
3ZLV
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Crystal structure of mouse acetylcholinesterase in complex with tabun and HI-6
分子名称: (2-hydroxyethoxy)acetaldehyde, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-(AMINOCARBONYL)-1-[({2-[(E)-(HYDROXYIMINO)METHYL]PYRIDINIUM-1-YL}METHOXY)METHYL]PYRIDINIUM, ...
著者Artursson, E, Andersson, P.O, Akfur, C, Linusson, A, Borjegren, S, Ekstrom, F.
登録日2013-02-04
公開日2013-03-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Catalytic-Site Conformational Equilibrium in Nerve-Agent Adducts of Acetylcholinesterase; Possible Implications for the Hi-6 Antidote Substrate Specificity.
Biochem.Pharmacol., 85, 2013
3ZSK
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Crystal structure of Human Galectin-3 CRD with glycerol bound at 0.90 angstrom resolution
分子名称: GALECTIN-3, GLYCEROL
著者Saraboji, K, Hakansson, M, Diehl, C, Nilsson, U.J, Leffler, H, Akke, M, Logan, D.T.
登録日2011-06-28
公開日2011-12-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献The Carbohydrate-Binding Site in Galectin-3 is Pre-Organized to Recognize a Sugar-Like Framework of Oxygens: Ultra-High Resolution Structures and Water Dynamics.
Biochemistry, 51, 2012

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