3ZLV

Crystal structure of mouse acetylcholinesterase in complex with tabun and HI-6

Summary for 3ZLV

Entry DOI	10.2210/pdb3zlv/pdb
Related	3ZLT 3ZLU
Descriptor	ACETYLCHOLINESTERASE, 4-(AMINOCARBONYL)-1-[({2-[(E)-(HYDROXYIMINO)METHYL]PYRIDINIUM-1-YL}METHOXY)METHYL]PYRIDINIUM, CARBONATE ION, ... (6 entities in total)
Functional Keywords	hydrolase, rvx, russian vx, cyclosarin
Biological source	MUS MUSCULUS (HOUSE MOUSE)
Cellular location	Cell junction, synapse. Isoform H: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side: P21836
Total number of polymer chains	2
Total formula weight	121310.75
Authors	Artursson, E.,Andersson, P.O.,Akfur, C.,Linusson, A.,Borjegren, S.,Ekstrom, F. (deposition date: 2013-02-04, release date: 2013-03-27, Last modification date: 2023-12-20)
Primary citation	Artursson, E.,Andersson, P.O.,Akfur, C.,Linusson, A.,Borjegren, S.,Ekstrom, F. Catalytic-Site Conformational Equilibrium in Nerve-Agent Adducts of Acetylcholinesterase; Possible Implications for the Hi-6 Antidote Substrate Specificity. Biochem.Pharmacol., 85:1389-, 2013 Cited by PubMed: 23376121 DOI: 10.1016/J.BCP.2013.01.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation