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6SA8
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BU of 6sa8 by Molmil
ring-like DARPin-Armadillo fusion H83_D01
分子名称: 1,2-ETHANEDIOL, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG, ring-like DARPin-Armadillo fusion H83_D01
著者Ernst, P, Honegger, A, van der Valk, F, Ewald, C, Mittl, P.R.E, Plucktun, A.
登録日2019-07-16
公開日2019-11-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Rigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts.
Sci Rep, 9, 2019
6S9M
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BU of 6s9m by Molmil
Designed Armadillo Repeat protein Lock2 fused to target peptide KRKRKAKITW
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Lock2_KRKRKAKITW, ...
著者Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A.
登録日2019-07-15
公開日2020-02-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
6SA6
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BU of 6sa6 by Molmil
DARPin-Armadillo fusion A5
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DARPin-Armadillo fusion A5
著者Ernst, P, Honegger, A, van der Valk, F, Ewald, C, Mittl, P.R.E, Pluckthun, A.
登録日2019-07-16
公開日2019-11-20
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Rigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts.
Sci Rep, 9, 2019
2LXO
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BU of 2lxo by Molmil
Identification of the Structural Traits Mediating the Antimicrobial Activity of a Chimeric Peptide of HBD2 and HBD3
分子名称: Chimeric Peptide
著者Spudy, B, Soennichsen, F.D, Waetzig, G.H, Grotzinger, J, Jung, S.
登録日2012-08-30
公開日2013-08-14
最終更新日2023-12-13
実験手法SOLUTION NMR
主引用文献Identification of structural traits that increase the antimicrobial activity of a chimeric peptide of human beta-defensins 2 and 3.
Biochem.Biophys.Res.Commun., 427, 2012
6SRW
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BU of 6srw by Molmil
Kemp Eliminase HG3.17 mutant Q50F, E47N, N300D Complexed with Transition State Analog 6-Nitrobenzotriazole
分子名称: 6-NITROBENZOTRIAZOLE, GLYCEROL, Kemp Eliminase HG3.17 Q50F
著者Bloch, J.S, Pinkas, D.M, Hilvert, D.
登録日2019-09-06
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Contribution of Oxyanion Stabilization to Kemp Eliminase Efficiencyproficiency
Acs Catalysis, 2020
2JWS
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BU of 2jws by Molmil
Solution NMR structures of two designed proteins with 88% sequence identity but different fold and function
分子名称: Ga88
著者He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J.
登録日2007-10-24
公開日2008-09-09
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献NMR structures of two designed proteins with high sequence identity but different fold and function
Proc.Natl.Acad.Sci.Usa, 105, 2008
6R28
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BU of 6r28 by Molmil
Structure of peptide P7, which binds Cdc42 and inhibits effector interactions.
分子名称: peptide P7
著者Murphy, N.P, Mott, H.R, Owen, D.
登録日2019-03-15
公開日2020-01-29
最終更新日2024-03-06
実験手法SOLUTION NMR
主引用文献The discovery and maturation of peptide biologics targeting the small G-protein Cdc42: A bioblockade for Ras-driven signaling.
J.Biol.Chem., 295, 2020
2N63
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BU of 2n63 by Molmil
Structure of C4VG16KRKP
分子名称: PENTANOIC ACID, antimicrobial peptide C4VG16KRKP
著者Bhunia, A, Datta, A.
登録日2015-08-11
公開日2016-03-23
最終更新日2024-01-24
実験手法SOLUTION NMR
主引用文献Designing potent antimicrobial peptides by disulphide linked dimerization and N-terminal lipidation to increase antimicrobial activity and membrane perturbation: Structural insights into lipopolysaccharide binding.
J Colloid Interface Sci, 461, 2016
6REL
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BU of 6rel by Molmil
Crystal structure of Pizza6-SH with CdCl2 nanocrystal
分子名称: CADMIUM ION, CHLORIDE ION, Pizza6-SH
著者Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D.
登録日2019-04-12
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Artificial beta-Propeller Protein-based Hydrolases
To Be Published
6REI
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BU of 6rei by Molmil
Crystal structure of Pizza6-S with Cd2+
分子名称: CADMIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D.
登録日2019-04-12
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Artificial beta-Propeller Protein-based Hydrolases
To Be Published
6REM
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BU of 6rem by Molmil
Crystal structure of Pizza6-SH with Sulphate ion
分子名称: Pizza6-SH, SULFATE ION
著者Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D.
登録日2019-04-12
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Artificial beta-Propeller Protein-based Hydrolases
To Be Published
2N8C
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BU of 2n8c by Molmil
Cystein knot with 2fp integrin avb6 cancer recognition site
分子名称: Cysteine knot
著者Filipp, F.V, Kimura, R, Tikole, S.
登録日2015-10-10
公開日2016-11-02
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Cystein knot with 2-FP label and integrin AvB6 cancer recognition site
To be Published
2JRE
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BU of 2jre by Molmil
C60-1, a PDZ domain designed using statistical coupling analysis
分子名称: C60-1 PDZ domain peptide
著者Larson, C, Stiffler, M, Li, P, Rosen, M, MacBeath, G, Ranganathan, R.
登録日2007-06-25
公開日2008-07-01
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献C60-1, a PDZ domain designed using statistical coupling analysis
To be Published
2KLW
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BU of 2klw by Molmil
Solution structure of an abc collagen heterotrimer reveals a single-register helix stabilized by electrostatic interactions
分子名称: (DOG)10, (PKG)10, (POG)10
著者Fallas, J.A, Gauba, V, Hartgerink, J.D.
登録日2009-07-09
公開日2009-07-21
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution structure of an ABC collagen heterotrimer reveals a single-register helix stabilized by electrostatic interactions.
J.Biol.Chem., 284, 2009
2JWU
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BU of 2jwu by Molmil
Solution NMR structures of two designed proteins with 88% sequence identity but different fold and function
分子名称: Gb88
著者He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J.
登録日2007-10-25
公開日2008-09-09
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR structures of two designed proteins with high sequence identity but different fold and function
Proc.Natl.Acad.Sci.Usa, 105, 2008
2L96
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BU of 2l96 by Molmil
Solution structure of LAK160-P7
分子名称: LAK160-P7
著者Vermeer, L.S, Bui, T.T, Lan, Y, Jumagulova, E, Kozlowska, J, McIntyre, C, Drake, A.F, Mason, J.A.
登録日2011-02-01
公開日2012-02-01
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The role of proline induced conformational flexibility in determining the antibacterial potency of linear cationic alpha-helical peptides
To be Published
2LR2
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BU of 2lr2 by Molmil
Designed IgG and lanthanide binding probe for solution NMR, MRI and luminescence microscopy
分子名称: Immunoglobulin G-binding protein A
著者Barb, A.W, Ho, T.G, Prestegard, J.H.
登録日2012-03-21
公開日2012-09-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Lanthanide binding and IgG affinity construct: Potential applications in solution NMR, MRI, and luminescence microscopy.
Protein Sci., 21, 2012
6SRZ
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BU of 6srz by Molmil
Kemp Eliminase HG3.17 mutant Q50H, E47N, N300D Complexed with Transition State Analog 6-Nitrobenzotriazole
分子名称: 6-NITROBENZOTRIAZOLE, GLYCEROL, Kemp Eliminase HG3.17 Q50H, ...
著者Bloch, J.S, Pinkas, D.M, Hilvert, D.
登録日2019-09-06
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Contribution of Oxyanion Stabilization to Kemp Eliminase Efficiencyproficiency
Acs Catalysis, 2020
2LQ4
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BU of 2lq4 by Molmil
Structural Characterization of an LPA1 Second Extracellular Loop Mimetic with a Self-Assembling Coiled-Coil Folding Constraint
分子名称: Lysophosphatidic acid receptor 1
著者Young, J.K.
登録日2012-02-23
公開日2013-01-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Characterization of an LPA1 Second Extracellular Loop Mimetic with a Self-Assembling Coiled-Coil Folding Constraint.
Int J Mol Sci, 14, 2013
2LFD
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BU of 2lfd by Molmil
Solution NMR structure of Diiron protein in presence of 2 eq Zn2+, Northeast Structural Genomics Consortium Target OR21
分子名称: Diiron protein, ZINC ION
著者Wu, Y, Pires, M, Mills, J.L, Reig, A, Szyperski, T, Degrado, W, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2011-06-29
公開日2011-08-24
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR structure of Diiron protein in presence of 2 eq Zn2+
To be Published
2MTT
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BU of 2mtt by Molmil
Non-reducible analogues of alpha-conotoxin RgIA: [3,12]-cis dicarba RgIA
分子名称: Dicarba Analogues of alpha-Conotoxin RgIA
著者Chhabra, S, Robinson, S.D, Norton, R.S.
登録日2014-08-31
公開日2014-11-26
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Dicarba Analogues of alpha-Conotoxin RgIA. Structure, Stability, and Activity at Potential Pain Targets.
J.Med.Chem., 57, 2014
2N09
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BU of 2n09 by Molmil
NMR structure of a short hydrophobic 11mer peptide in DMSO-d6/H2O (1:3) solution
分子名称: Short hydrophobic peptide with cyclic constraints
著者Hoang, H.N, Song, K, Hill, T.A, Derksen, D.R, Edmonds, D.J, Kok, W.M, Limberakis, C, Liras, S, Loria, P.M, Mascitti, V, Mathiowetz, A.M, Mitchell, J.M, Piotrowski, D.W, Price, D.A, Stanton, R.V, Suen, J.Y, Withka, J.M, Griffith, D.A, Fairlie, D.P.
登録日2015-03-04
公開日2015-04-15
最終更新日2015-05-27
実験手法SOLUTION NMR
主引用文献Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) Agonists.
J.Med.Chem., 58, 2015
2K76
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BU of 2k76 by Molmil
Solution structure of a paralog-specific Mena binder by NMR
分子名称: pGolemi
著者Link, N.M, Hunke, C, Eichler, J, Bayer, P.
登録日2008-08-03
公開日2009-06-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of pGolemi, a high affinity Mena EVH1 binding miniature protein, suggests explanations for paralog-specific binding to Ena/VASP homology (EVH) 1 domains.
Biol.Chem., 390, 2009
2N65
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BU of 2n65 by Molmil
Disulphide linked homodimer of designed antimicrobial peptide VG16KRKP
分子名称: antimicrobial peptide VG16KRKP
著者Datta, A, Bhunia, A.
登録日2015-08-12
公開日2016-03-23
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Designing potent antimicrobial peptides by disulphide linked dimerization and N-terminal lipidation to increase antimicrobial activity and membrane perturbation: Structural insights into lipopolysaccharide binding.
J Colloid Interface Sci, 461, 2016
2MWL
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BU of 2mwl by Molmil
NMR structure of VG16KRKP, an antimicrobial peptide in LPS
分子名称: antimicrobial peptide
著者Bhunia, A, Datta, A.
登録日2014-11-13
公開日2014-12-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Antimicrobial Peptides: Insights into Membrane Permeabilization, Lipopolysaccharide Fragmentation and Application in Plant Disease Control.
Sci Rep, 5, 2015

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