PDB: 45459 件ウェブページステータス検索Chemie searchBIRD

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6QDD	Leishmania major N-myristoyltransferase in complex with thienopyrimidine inhibitor IMP-0000105 分子名称: 2-[(2~{S})-1-[2-[methyl-(1-methylpiperidin-4-yl)amino]thieno[3,2-d]pyrimidin-4-yl]-2,3-dihydropyrrol-2-yl]ethanenitrile, DIMETHYL SULFOXIDE, Glycylpeptide N-tetradecanoyltransferase, ... 著者 Brannigan, J.A. 登録日 2019-01-01 公開日 2020-05-06 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Novel Thienopyrimidine Inhibitors of Leishmania N -Myristoyltransferase with On-Target Activity in Intracellular Amastigotes. J.Med.Chem., 63, 2020
6QDC	Leishmania major N-myristoyltransferase in complex with thienopyrimidine inhibitor IMP-0000101 分子名称: 3-[[2-[(1-ethylpiperidin-4-yl)-methyl-amino]thieno[3,2-d]pyrimidin-4-yl]-methyl-amino]propanenitrile, Glycylpeptide N-tetradecanoyltransferase, MAGNESIUM ION, ... 著者 Brannigan, J.A. 登録日 2019-01-01 公開日 2020-05-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Novel Thienopyrimidine Inhibitors of Leishmania N -Myristoyltransferase with On-Target Activity in Intracellular Amastigotes. J.Med.Chem., 63, 2020
6YRZ	Crystal structure of FAP et pH 8.5 after illumination at 150K 分子名称: CARBON DIOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, Fatty acid photodecarboxylase, ... 著者 Sorigue, D, Legrand, P, Blangy, S, Beisson, F, Arnoux, P. 登録日 2020-04-20 公開日 2021-04-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.824 Å) 主引用文献 Mechanism and dynamics of fatty acid photodecarboxylase. Science, 372, 2021
6YS1	Crystal structure of FAP R451K mutant in the dark at 100K 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Fatty acid Photodecarboxylase, STEARIC ACID, ... 著者 Sorigue, D, Gotthard, G, Blangy, S, Nurizzo, D, Royant, A, Beisson, F, Arnoux, P. 登録日 2020-04-20 公開日 2021-04-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Mechanism and dynamics of fatty acid photodecarboxylase. Science, 372, 2021
6C5W	Crystal structure of the mitochondrial calcium uniporter 分子名称: CALCIUM ION, calcium uniporter, nanobody 著者 Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L. 登録日 2018-01-17 公開日 2018-07-11 最終更新日 2019-04-24 実験手法 X-RAY DIFFRACTION (3.10010242 Å) 主引用文献 X-ray and cryo-EM structures of the mitochondrial calcium uniporter. Nature, 559, 2018
6YOP	Structure of SAMM50 LIR bound to GABARAP 分子名称: Sorting and assembly machinery component 50 homolog,Gamma-aminobutyric acid receptor-associated protein 著者 Mouilleron, S, Wenxin, Z, Johansen, T, Tooze, S, Abudu, Y.P, Lamark, T. 登録日 2020-04-14 公開日 2021-04-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Structure of SAMM50 LIR bound to GABARAP To Be Published
6C87	Crystal structure of rab gdp dissociation inhibitor alpha from Naegleria fowleri 分子名称: Rab GDP dissociation inhibitor alpha, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-01-24 公開日 2018-02-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of rab gdp dissociation inhibitor alpha from Naegleria fowleri TO BE PUBLISHED
5KX9	Selective Small Molecule Inhibition of the FMN Riboswitch 分子名称: (6P)-2-{(3S)-1-[(2-methoxypyrimidin-5-yl)methyl]piperidin-3-yl}-6-(thiophen-2-yl)pyrimidin-4-ol, FMN Riboswitch, MAGNESIUM ION, ... 著者 Fischmann, T.O. 登録日 2016-07-20 公開日 2016-08-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Atomic resolution mechanistic studies of ribocil: A highly selective unnatural ligand mimic of the E. coli FMN riboswitch. Rna Biol., 13, 2016
5L84	Structure of the H959F variant of the PpsC dehydratase domain from Mycobacterium tuberculosis 分子名称: Phthiocerol synthesis polyketide synthase type I PpsC 著者 Faille, A, Gavalda, S, Mourey, L, Pedelacq, J.D. 登録日 2016-06-07 公開日 2017-08-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases. J. Mol. Biol., 429, 2017
6QGG	Structure of human Bcl-2 in complex with analogue of ABT-737 分子名称: Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2,Bcl-2-like protein 1, [(3~{R})-3-[[4-[[4-[4-[[2-(4-chlorophenyl)phenyl]methyl]piperazin-1-yl]phenyl]carbonylsulfamoyl]-2-nitro-phenyl]amino]-4-phenylsulfanyl-butyl]-(2-hydroxy-2-oxoethyl)-dimethyl-azanium 著者 Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. 登録日 2019-01-11 公開日 2019-06-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1. Acs Omega, 4, 2019
5KYB	Crystal structure of the apo-form of USP7 catalytic domain [V302K] mutant 分子名称: GLYCEROL, Ubiquitin carboxyl-terminal hydrolase 7 著者 Rouge, L, Ozen, A. 登録日 2016-07-21 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation. Structure, 26, 2018
5LB6	HIF prolyl hydroxylase 2 (PHD2/EGLN1) R371H variant in complex with Mn(II) and N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9) 分子名称: Egl nine homolog 1, GLYCEROL, MANGANESE (II) ION, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2016-06-15 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases. Nat Commun, 7, 2016
6Y1U	Mycobacterium tuberculosis FtsZ-GDP in complex with 4-hydroxycoumarin 分子名称: 4-HYDROXY-2H-CHROMEN-2-ONE, Cell division protein FtsZ, DIMETHYL SULFOXIDE, ... 著者 Alnami, A.T, Norton, R.S, Pena, H.P, Haider, M, kozielski, F. 登録日 2020-02-13 公開日 2021-06-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Conformational Flexibility of A Highly Conserved Helix Controls Cryptic Pocket Formation in FtsZ. J.Mol.Biol., 433, 2021
6Y1V	Mycobacterium tuberculosis FtsZ-GTP-gamma-S in complex with 4-hydroxycoumarin 分子名称: 4-HYDROXY-2H-CHROMEN-2-ONE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Cell division protein FtsZ, ... 著者 Alnami, A.T, Norton, R.S, Pena, H.P, Haider, M, kozielski, F. 登録日 2020-02-13 公開日 2021-06-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Conformational Flexibility of A Highly Conserved Helix Controls Cryptic Pocket Formation in FtsZ. J.Mol.Biol., 433, 2021
6Y1I	Human Eg5 motor domain mutant R234C 分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION 著者 Garcia-Saez, I, Skoufias, D.A. 登録日 2020-02-12 公開日 2021-06-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Human Eg5 motor domain mutant R234C To Be Published
6G7H	Retinal isomerization in bacteriorhodopsin revealed by a femtosecond X-ray laser: resting state structure 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, Bacteriorhodopsin, ... 著者 Nogly, P, Weinert, T, James, D, Cabajo, S, Ozerov, D, Furrer, A, Gashi, D, Borin, V, Skopintsev, P, Jaeger, K, Nass, K, Bath, P, Bosman, R, Koglin, J, Seaberg, M, Lane, T, Kekilli, D, Bruenle, S, Tanaka, T, Wu, W, Milne, C, White, T, Barty, A, Weierstall, U, Panneels, V, Nango, E, Iwata, S, Hunter, M, Schapiro, I, Schertler, G, Neutze, R, Standfuss, J. 登録日 2018-04-06 公開日 2018-06-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser. Science, 361, 2018
5KJ8	Structure of the Ca2+-bound synaptotagmin-1 SNARE complex (long unit cell form) - from synchrotron diffraction 分子名称: CALCIUM ION, Synaptosomal-associated protein 25, Synaptotagmin-1, ... 著者 Lyubimov, A.Y, Uervirojnangkoorn, M, Zhou, Q, Zhao, M, Sauter, N.K, Brewster, A.S, Weis, W.I, Brunger, A.T. 登録日 2016-06-17 公開日 2016-10-19 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Advances in X-ray free electron laser (XFEL) diffraction data processing applied to the crystal structure of the synaptotagmin-1 / SNARE complex. Elife, 5, 2016
5L20	Crystal Structure of a Clostripain (BT_0727) from Bacteroides thetaiotaomicron ATCC 29148 in Complex with Peptide Inhibitor BTN-VLTK-AOMK 分子名称: Clostripain-related protein, Peptide Inhibitor BTN-VLTK-AOMK 著者 Wolan, D.W, Roncase, E.J. 登録日 2016-07-29 公開日 2017-08-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal Structure of a Clostripain (BT_0727) from Bacteroides thetaiotaomicron ATCC 29148 in Complex with Peptide Inhibitor BTN-VLTK-AOMK To be published
6BUC	Structure of a new ShKT peptide from the sea anemone Oulactis sp. 分子名称: OspTx2b 著者 Krishnarjuna, B, Norton, R.S. 登録日 2017-12-10 公開日 2018-05-30 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Synthesis, folding, structure and activity of a predicted peptide from the sea anemone Oulactis sp. with an ShKT fold. Toxicon, 150, 2018
6PX4	Crystal structure of the complex between periplasmic domains of antiholin RI and holin T from T4 phage, in H32 分子名称: Antiholin, Holin 著者 Krieger, I.V, Sacchettini, J.C. 登録日 2019-07-24 公開日 2020-06-24 最終更新日 2020-08-12 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The Structural Basis of T4 Phage Lysis Control: DNA as the Signal for Lysis Inhibition. J.Mol.Biol., 432, 2020
6FOW	The crystal structure of EncM complexed with dioxygen under 10 bar of oxygen pressure. 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, OXYGEN MOLECULE, Putative FAD-dependent oxygenase EncM 著者 Saleem-Batcha, R, Teufel, R. 登録日 2018-02-08 公開日 2018-05-02 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Enzymatic control of dioxygen binding and functionalization of the flavin cofactor. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6YMC	26-mer stem-loop RNA 分子名称: BARIUM ION, RNA (26-MER) 著者 Janowski, R, Niessing, D. 登録日 2020-04-08 公開日 2022-04-20 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Multiple intrinsically disordered RNA-binding motifs cooperate as RNA-folding catalyst and mediate phase transition To Be Published
6YQ5	Hybrid structure of the SPP1 tail tube by solid-state NMR and cryo EM - NMR Ensemble 分子名称: Tail tube protein gp17.1* 著者 Zinke, M, Sachowsky, K.A.A, Zinn-Justin, S, Ravelli, R, Schroder, G.F, Habeck, M, Lange, A. 登録日 2020-04-16 公開日 2020-10-14 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR 主引用文献 Architecture of the flexible tail tube of bacteriophage SPP1. Nat Commun, 11, 2020
6CB0	Crystal Structure of the FAK FERM domain 分子名称: Focal adhesion kinase 1 著者 Dementiev, A, Marlowe, T. 登録日 2018-02-01 公開日 2019-02-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 High resolution crystal structure of the FAK FERM domain reveals new insights on the Druggability of tyrosine 397 and the Src SH3 binding site. BMC Mol Cell Biol, 20, 2019
6FRA	F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101 分子名称: 1,2-ETHANEDIOL, Human T-Cell Receptor F11 alpha Chain, Human T-Cell Receptor F11 beta Chain, ... 著者 Rizkallah, P.J, Cole, D.K. 登録日 2018-02-15 公開日 2018-04-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility. Front Immunol, 9, 2018

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