PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

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4ZT6	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-[(4R)-6,8-dichloro-3,4-dihydro-2H-chromen-4-yl]-N'-(5-fluoro-1H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1709) 分子名称: DIMETHYL SULFOXIDE, METHIONINE, Methionyl-tRNA synthetase, ... 著者 Koh, C.-Y, Hol, W.G.J. 登録日 2015-05-14 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors. Acs Infect Dis., 2, 2016
6XLV	Crystal structure of leukemia-associated N196K mutant of U2AF65 bound to AdML splice site 分子名称: DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit 著者 Maji, D, Jenkins, J.L, Kielkopf, C.L. 登録日 2020-06-29 公開日 2020-10-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing. J.Biol.Chem., 295, 2020
4ZTV	Non-anthranilate-like inhibitor (TAMU-A7) complexed with anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis in absence of PRPP 分子名称: 4,4,4-trifluoro-1-(4-methoxyphenyl)butane-1,3-dione, Anthranilate phosphoribosyltransferase 著者 Evans, G.L, Eom, J, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) 登録日 2015-05-15 公開日 2016-05-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Bioactive non-anthranilate-like fragment-like inhibitor provides alternative starting point for inhibitor design against anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis. To be Published
6LER	169 bp nucleosome harboring non-identical cohesive DNA termini. 分子名称: CALCIUM ION, DNA (169-MER), Histone H2A type 1-B/E, ... 著者 Sharma, D, Adhireksan, Z, Lee, P.L, Davey, C.A. 登録日 2019-11-26 公開日 2021-03-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Engineering nucleosomes for generating diverse chromatin assemblies. Nucleic Acids Res., 49, 2021
7D5Q	Structure of NorC transporter (K398A mutant) in an outward-open conformation in complex with a single-chain Indian camelid antibody 分子名称: Drug transporter, putative, ICab, ... 著者 Kumar, S, Athreya, A, Penmatsa, A. 登録日 2020-09-27 公開日 2021-06-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody. Commun Biol, 4, 2021
7DT2	Strategic design of catalytic lysine-targeting reversible covalent BCR-ABL Inhibitors 分子名称: Tyrosine-protein kinase ABL1, [4-[5-[5-(dimethylcarbamoyl)pyridin-3-yl]-1H-pyrrolo[2,3-b]pyridin-3-yl]-2-methanoyl-5-methoxy-phenyl]boronic acid 著者 Anantharajan, J, Baburajendran, N. 登録日 2021-01-04 公開日 2021-06-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Strategic Design of Catalytic Lysine-Targeting Reversible Covalent BCR-ABL Inhibitors*. Angew.Chem.Int.Ed.Engl., 60, 2021
4ZW7	X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9m 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-19 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
6L4J	Monomer structure of monellin loop1 mutant (YEPKG) 分子名称: Single chain Monellin 著者 Manjula, R, Ramaswamy, S, Gosavi, S. 登録日 2019-10-17 公開日 2021-04-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Monomer structure of Loop1 mutant Monellin with YEPKG motif To Be Published
6XPV	Nucleoside Diphosphate Kinase from Aspergillus fumgiatus Af293 bound to dTDP 分子名称: Nucleoside diphosphate kinase, THYMIDINE-5'-DIPHOSPHATE 著者 Nguyen, S, Bruning, J.B. 登録日 2020-07-09 公開日 2020-11-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase. Febs J., 288, 2021
6XQT	Room-temperature X-ray Crystal structure of SARS-CoV-2 main protease in complex with Narlaprevir 分子名称: (1R,2S,5S)-3-[N-({1-[(tert-butylsulfonyl)methyl]cyclohexyl}carbamoyl)-3-methyl-L-valyl]-N-{(1S)-1-[(1R)-2-(cyclopropylamino)-1-hydroxy-2-oxoethyl]pentyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase 著者 Kneller, D.W, Kovalevsky, A, Coates, L. 登録日 2020-07-10 公開日 2020-07-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Malleability of the SARS-CoV-2 3CL M pro Active-Site Cavity Facilitates Binding of Clinical Antivirals. Structure, 28, 2020
6L44	Monomeric structure of monellin loop1 mutant with QVPAG motif 分子名称: SULFATE ION, Single chain Monellin 著者 Manjula, R, Ramaswamy, S, Gosavi, S. 登録日 2019-10-16 公開日 2021-04-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.492 Å) 主引用文献 The monomer structure of Monellin Loop1 mutant To Be Published
5ADK	Structure of bovine endothelial nitric oxide synthase heme domain in complex with 7-((3-(Dimethylamino)methyl)phenoxy)methyl)quinolin-2- amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[[3-[(dimethylamino)methyl]phenoxy]methyl]quinolin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2015-08-20 公開日 2015-10-28 最終更新日 2015-11-25 実験手法 X-RAY DIFFRACTION (1.805 Å) 主引用文献 Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem., 58, 2015
6L4N	Domain swapped dimer of Monellin loop1 mutant with QVPAG motif 分子名称: MAGNESIUM ION, Single chain Monellin 著者 Manjula, R, Ramaswamy, S, Gosavi, S. 登録日 2019-10-18 公開日 2021-04-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.431 Å) 主引用文献 Domain swapped dimer of Monellin lopp1 mutant with QVPAG motif To Be Published
4ZY8	K. lactis Lst4 longin domain 分子名称: Protein LST4 著者 Pacitto, A, Ascher, D.B, Blundell, T.L. 登録日 2015-05-21 公開日 2016-04-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Lst4, the yeast Fnip1/2 orthologue, is a DENN-family protein. Open Biology, 5, 2015
6L4I	Monomeric structure of monellin loop1 mutant with QEPKG motif 分子名称: Single chain Monellin 著者 Manjula, R, Ramaswamy, S, Gosavi, S. 登録日 2019-10-17 公開日 2021-04-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Monomer structure of Loop1 mutant Monellin with QEPKG motif To Be Published
7DJR	Crystal structure of SARS-CoV-2 main protease (no ligand) 分子名称: 3C-like proteinase, DIMETHYL SULFOXIDE 著者 Deetanya, P, Wangkanont, K. 登録日 2020-11-21 公開日 2021-06-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Interaction of 8-anilinonaphthalene-1-sulfonate with SARS-CoV-2 main protease and its application as a fluorescent probe for inhibitor identification. Comput Struct Biotechnol J, 19, 2021
4ZYQ	X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10s 分子名称: CARBONATE ION, N-{(1R)-2-(hydroxyamino)-1-[3'-(N'-hydroxycarbamimidoyl)biphenyl-4-yl]-2-oxoethyl}-2,2-dimethylpropanamide, PENTAETHYLENE GLYCOL, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-22 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
6LAY	Domain-swapped dimer structure of a Single-chain Monellin loop1-delta4-QVVAG mutant 分子名称: Monellin chain B,Monellin chain A 著者 Manjula, R, Subramanian, R, Gosavi, S. 登録日 2019-11-13 公開日 2021-05-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.001 Å) 主引用文献 Domain-swapped dimer structure of a Single-chain Monellin loop1-delta4-QVVAG mutant To Be Published
6XVP	Crystal structure of Neprilysin in complex with Sampatrilat. 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Neprilysin, ... 著者 Cozier, G.E, Acharya, K.R, Sharma, U. 登録日 2020-01-22 公開日 2020-05-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Molecular Basis for Omapatrilat and Sampatrilat Binding to Neprilysin-Implications for Dual Inhibitor Design with Angiotensin-Converting Enzyme. J.Med.Chem., 63, 2020
5AA3	Crystal structure of MltF from Pseudomonas aeruginosa in the presence of tetrasaccharide and tetrapeptide 分子名称: GLUTAMIC ACID, MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F 著者 Dominguez-Gil, T, Acebron, I, Hermoso, J.A. 登録日 2015-07-23 公開日 2016-10-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa. Structure, 24, 2016
4ZZU	Geotrichum candidum Cel7A structure complex with thio-linked cellotetraose at 1.4A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CELLOBIOHYDROLASE I, ... 著者 Borisova, A.S, Stahlberg, J. 登録日 2015-04-14 公開日 2015-09-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Sequencing, Biochemical Characterization, Crystal Structure and Molecular Dynamics of Cellobiohydrolase Cel7A from Geotrichum Candidum 3C. FEBS J., 282, 2015
5AEJ	Crystal structure of human Gremlin-1 分子名称: GREMLIN-1, SULFATE ION 著者 Kisonaite, M, Hyvonen, M. 登録日 2015-08-31 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.904 Å) 主引用文献 Structure of Gremlin-1 and Analysis of its Interaction with Bmp-2. Biochem.J., 473, 2016
6XX3	Crystal structure of the c-Src SH3 domain H122R-Q128E mutant in complex with Cu(II) at pH 6.5 co-crystallized with methyl beta-cyclodextrin 分子名称: COPPER (II) ION, Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, Proto-oncogene tyrosine-protein kinase Src 著者 Camara-Artigas, A. 登録日 2020-01-26 公開日 2020-04-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase. J.Biol.Inorg.Chem., 25, 2020
6XY4	Structural insight into sheep-pox virus mediated inhibition of apoptosis 分子名称: Activator of apoptosis harakiri, anti-apoptotic membrane protein 著者 Suraweera, C.D, Hinds, M.G, Kvansakul, M. 登録日 2020-01-29 公開日 2020-07-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.04623151 Å) 主引用文献 Crystal structures of the sheeppox virus encoded inhibitor of apoptosis SPPV14 bound to the proapoptotic BH3 peptides Hrk and Bax. Febs Lett., 594, 2020
6XZ3	Crystal structure of TLNRD1 4-helix bundle 分子名称: 1,2-ETHANEDIOL, Talin rod domain-containing protein 1 著者 Cowell, A, Singh, A.K, Brown, D.G, Goult, B.T. 登録日 2020-02-01 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Talin rod domain-containing protein 1 (TLNRD1) is a novel actin-bundling protein which promotes filopodia formation. J.Cell Biol., 220, 2021

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