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6O4Z
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BU of 6o4z by Molmil
Structure of HLA-A2:01 with peptide MM92
分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ...
著者Ying, G, Bitra, A, Zajonc, D.M.
登録日2019-03-01
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Anin silico-in vitroPipeline Identifying an HLA-A*02:01+KRAS G12V+Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients.
Front Immunol, 10, 2019
6O51
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BU of 6o51 by Molmil
Structure of HLA-A2:01 with peptide MM90
分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ...
著者Ying, G, Bitra, A, Zajonc, D.M.
登録日2019-03-01
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Anin silico-in vitroPipeline Identifying an HLA-A*02:01+KRAS G12V+Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients.
Front Immunol, 10, 2019
8UVR
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BU of 8uvr by Molmil
Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with spectinomycin, mRNA, deacylated A- and E-site tRNAphe, and deacylated P-site tRNAmet at 2.60A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Killam, B.Y, Phelps, G.A, Lee, R.E, Polikanov, Y.S.
登録日2023-11-03
公開日2024-08-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Proc.Natl.Acad.Sci.USA, 121, 2024
8J30
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BU of 8j30 by Molmil
Crystal structure of ApNGT with Q469A and M218A mutations in complex with UDP-GLC
分子名称: UDP-glucose:protein N-beta-glucosyltransferase, URIDINE-5'-DIPHOSPHATE, URIDINE-5'-DIPHOSPHATE-GLUCOSE
著者Feng, Y, Hao, Z, Guo, Q, Zheng, J, Da, L, Peng, W.
登録日2023-04-15
公開日2023-08-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Investigation of the Catalytic Mechanism of a Soluble N-glycosyltransferase Allows Synthesis of N-glycans at Noncanonical Sequons.
Jacs Au, 3, 2023
7UG7
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BU of 7ug7 by Molmil
70S ribosome complex in an intermediate state of translocation bound to EF-G(GDP) stalled by Argyrin B
分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
著者Rundlet, E.J, Wieland, M, Holm, M, Koller, T.O, Blanchard, S.C, Wilson, D.N.
登録日2022-03-24
公開日2022-05-18
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Proc.Natl.Acad.Sci.USA, 119, 2022
6OBV
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BU of 6obv by Molmil
Structural insights into dehydratase substrate selection for the borrelidin and fluvirucin polyketide synthases
分子名称: fluvirucin B1 DH domain from module 1
著者McAndrew, R.P, Barajas, J.F, Pereira, J.H, Keasling, J.D, Adams, P.D.
登録日2019-03-21
公開日2019-06-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural insights into dehydratase substrate selection for the borrelidin and fluvirucin polyketide synthases.
J Ind Microbiol Biotechnol., 46, 2019
8K5S
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BU of 8k5s by Molmil
The structure of EntE with 3-(prop-2-yn-1-yloxy)benzoic acid sulfamoyl adenosine
分子名称: Enterobactin synthase component E, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-(3-prop-2-ynoxyphenyl)carbonylsulfamate
著者Miyanaga, A, Ishikawa, F.
登録日2023-07-24
公開日2024-07-31
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Reprogrammed aryl acid adenylation domain with an enlarged substrate binding pocket
To be published
8K5T
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BU of 8k5t by Molmil
The structure of EntE with2-methyl-3-chloro-benzoic acid sulfamoyl adenosine
分子名称: Enterobactin synthase component E, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-(3-chloranyl-2-methyl-phenyl)carbonylsulfamate
著者Miyanaga, A, Ishikawa, F.
登録日2023-07-24
公開日2024-07-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Reprogrammed aryl acid adenylation domain with an enlarged substrate binding pocket
To be published
3JC2
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BU of 3jc2 by Molmil
The structure of the mammalian Sec61 channel opened by a signal sequence
分子名称: Prolactin, Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, ...
著者Voorhees, R.M, Hegde, R.S.
登録日2015-11-15
公開日2016-01-13
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of the Sec61 channel opened by a signal sequence.
Science, 351, 2016
2A02
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BU of 2a02 by Molmil
Solution NMR Structure of the Periplasmic Signaling Domain of the Outer Membrane Iron Transporter PupA from Pseudomonas putida.
分子名称: Ferric-pseudobactin 358 receptor
著者Ferguson, A.D, Amezcua, C.A, Chelliah, Y, Rosen, M.K, Deisenhofer, J.
登録日2005-06-15
公開日2006-09-26
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Signal transduction pathway of TonB-dependent transporters.
Proc.Natl.Acad.Sci.Usa, 2, 2006
3HLF
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BU of 3hlf by Molmil
Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant, S76A mutant, complex with simvastatin
分子名称: Simvastatin acid, Transesterase
著者Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y.
登録日2009-05-27
公開日2009-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol., 16, 2009
4NXQ
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BU of 4nxq by Molmil
Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) in Complex With Caspr4 Peptide
分子名称: Contactin-associated protein-like 4 peptide, T-lymphoma invasion and metastasis-inducing protein 1
著者Liu, X, Speckhard, D.C, Shepherd, T.R, Hengel, S.R, Fuentes, E.J.
登録日2013-12-09
公開日2015-05-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions.
Structure, 24, 2016
6UH3
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BU of 6uh3 by Molmil
Crystal structure of bacterial heliorhodopsin 48C12
分子名称: DI(HYDROXYETHYL)ETHER, Heliorhodopsin, PALMITIC ACID, ...
著者Lu, Y, Zhou, X.E, Gao, X, Xia, R, Xu, Z, Wang, N, Leng, Y, Melcher, K, Xu, H.E, He, Y.
登録日2019-09-26
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of heliorhodopsin 48C12.
Cell Res., 30, 2020
6UVQ
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BU of 6uvq by Molmil
Crystal structure of Apo AtmM
分子名称: ACETATE ION, D-glucose O-methyltransferase, MAGNESIUM ION
著者Alvarado, S.K, Wang, Z, Miller, M.D, Thorson, J.S, Phillips Jr, G.N.
登録日2019-11-04
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structure of Apo AtmM
To Be Published
6UWD
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BU of 6uwd by Molmil
Crystal structure of Apo AtmM
分子名称: ACETATE ION, D-glucose O-methyltransferase, MAGNESIUM ION
著者Alvarado, S.K, Wang, Z, Miller, M.D, Thorson, J.S, Phillips Jr, G.N.
登録日2019-11-05
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structure of Apo AtmM
To Be Published
4XWF
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BU of 4xwf by Molmil
Crystal structure of the ZMP riboswitch at 1.80 angstrom
分子名称: AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, CACODYLATE ION, IRIDIUM HEXAMMINE ION, ...
著者Trausch, J.J, Batey, R.T.
登録日2015-01-28
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Metal Ion-Mediated Nucleobase Recognition by the ZTP Riboswitch.
Chem.Biol., 22, 2015
4XW7
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BU of 4xw7 by Molmil
Crystal structure of the ZMP riboswitch at 2.50 angstrom
分子名称: AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, IRIDIUM HEXAMMINE ION, MAGNESIUM ION, ...
著者Trausch, J.J, Batey, R.T.
登録日2015-01-28
公開日2015-09-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Metal Ion-Mediated Nucleobase Recognition by the ZTP Riboswitch.
Chem.Biol., 22, 2015
8FHJ
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BU of 8fhj by Molmil
Crystal structure of a FAD monooxygenease from Methylocystis sp. Strain SB2
分子名称: BROMIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Stewart, A.M, Sawaya, M.R, Stewart, C.E.
登録日2022-12-14
公開日2023-05-03
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Crystal structure of MbnF: an NADPH-dependent flavin monooxygenase from Methylocystis strain SB2.
Acta Crystallogr.,Sect.F, 79, 2023
6UV6
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BU of 6uv6 by Molmil
AtmM with bound rebeccamycin analogue
分子名称: 12-beta-D-glucopyranosyl-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione, D-glucose O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Alvarado, S.K, Wang, Z, Miller, M.D, Thorson, J.S, Phillips Jr, G.N.
登録日2019-11-01
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structure of AtmM Bound with Glycosylated Indolocarbazole
To Be Published
6WB7
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BU of 6wb7 by Molmil
Acarbose Kinase AcbK as a Complex with Acarbose and AMP-PNP
分子名称: 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Acarbose 7(IV)-phosphotransferase, MANGANESE (II) ION, ...
著者Jeffrey, P.D, Balaich, J.N, Estrella, M.A, Donia, M.S.
登録日2020-03-26
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献The human microbiome encodes resistance to the antidiabetic drug acarbose.
Nature, 600, 2021
7WIV
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BU of 7wiv by Molmil
Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with an AMP-PNP
分子名称: Mycobactin import ATP-binding/permease protein IrtA, Mycobactin import ATP-binding/permease protein IrtB, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Zhang, B, Sun, S, Yang, H, Rao, Z.
登録日2022-01-05
公開日2023-01-25
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB.
Protein Cell, 14, 2023
7WIU
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BU of 7wiu by Molmil
Cryo-EM structure of Mycobacterium tuberculosis irtAB in inward-facing state
分子名称: Mycobactin import ATP-binding/permease protein IrtA, Mycobactin import ATP-binding/permease protein IrtB
著者Zhang, B, Sun, S, Yang, H, Rao, Z.
登録日2022-01-05
公開日2023-01-25
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB.
Protein Cell, 14, 2023
8GJP
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BU of 8gjp by Molmil
A1 Int graft: Adenylation domain 1 core construct from teicoplanin biosynthesis, intermediate selection pocket graft
分子名称: MbtH-like short polypeptide, Non-ribosomal peptide synthetase
著者Hansen, M.H, Cryle, M.J.
登録日2023-03-16
公開日2023-12-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides.
Nat Commun, 14, 2023
8GJ4
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BU of 8gj4 by Molmil
A1 Tei: Adenylation domain 1 core construct from teicoplanin biosynthesis
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, MbtH-like short polypeptide, ...
著者Hansen, M.H, Cryle, M.J.
登録日2023-03-14
公開日2023-12-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides.
Nat Commun, 14, 2023
8GKM
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BU of 8gkm by Molmil
A1 Leu graft + Leu: Adenylation domain 1 core construct from teicoplanin biosynthesis, leucine selection pocket graft; leucine bound
分子名称: ACETIC ACID, DI(HYDROXYETHYL)ETHER, LEUCINE, ...
著者Hansen, M.H, Cryle, M.J.
登録日2023-03-20
公開日2023-12-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides.
Nat Commun, 14, 2023

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件を2024-09-04に公開中

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