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6UJI
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BU of 6uji by Molmil
Low resolution crystal structure (5.5 A) of the anthrax toxin protective antigen heptamer prepore D425A mutant
分子名称: Protective antigen PA-63
著者Lovell, S, Mehzabeen, N, Battaile, K.P, Bann, J.G.
登録日2019-10-03
公開日2020-10-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (5.5 Å)
主引用文献Structure of the anthrax protective antigen D425A dominant negative mutant reveals a stalled intermediate state of pore maturation.
J.Mol.Biol., 2022
6AZP
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BU of 6azp by Molmil
A Structurally Dynamic N-terminal Region Drives Function of the Staphylococcal Peroxidase Inhibitor (SPIN)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Ramyar, K.X, Geisbrecht, B.V.
登録日2017-09-11
公開日2017-12-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.291 Å)
主引用文献A structurally dynamic N-terminal region drives function of the staphylococcal peroxidase inhibitor (SPIN).
J. Biol. Chem., 293, 2018
6UZB
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BU of 6uzb by Molmil
Anthrax toxin protective antigen channels bound to edema factor
分子名称: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen
著者Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A.
登録日2019-11-14
公開日2020-03-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors.
Nat Commun, 11, 2020
6UZE
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BU of 6uze by Molmil
Anthrax toxin protective antigen channels bound to edema factor
分子名称: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen
著者Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A.
登録日2019-11-15
公開日2020-03-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors.
Nat Commun, 11, 2020
6UZD
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BU of 6uzd by Molmil
Anthrax toxin protective antigen channels bound to edema factor
分子名称: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen
著者Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A.
登録日2019-11-14
公開日2020-03-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors.
Nat Commun, 11, 2020
6BHX
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BU of 6bhx by Molmil
B. subtilis SsbA with DNA
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Single-stranded DNA-binding protein A
著者Dubiel, K.D, Myers, A.R, Satyshur, K.A, Keck, J.L.
登録日2017-10-31
公開日2018-12-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.936 Å)
主引用文献Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins.
J. Mol. Biol., 431, 2019
5VGM
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BU of 5vgm by Molmil
Crystal structure of dihydroorotase pyrC from Vibrio cholerae in complex with zinc at 1.95 A resolution.
分子名称: ACETATE ION, CHLORIDE ION, Dihydroorotase, ...
著者Lipowska, J, Shabalin, I.G, Miks, C.D, Winsor, J, Cooper, D.R, Shuvalova, L, Kwon, K, Lewinski, K, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-04-11
公開日2017-04-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Pyrimidine biosynthesis in pathogens - Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholerae.
Int.J.Biol.Macromol., 136, 2019
6CJ7
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BU of 6cj7 by Molmil
Crystal structure of Manduca sexta Serine protease inhibitor (Serpin)-12
分子名称: Serpin-12
著者Gulati, M, Hu, Y, Peng, S, Pathak, P.K, Wang, Y, Deng, J, Jiang, H.
登録日2018-02-26
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Manduca sexta serpin-12 controls the prophenoloxidase activation system in larval hemolymph.
Insect Biochem. Mol. Biol., 99, 2018
5LAC
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BU of 5lac by Molmil
SeMet Labeled Derivative of Cavally Virus 3CL Protease
分子名称: 3Cl Protease, GLYCEROL
著者Kanitz, M, Heine, A, Diederich, W.E.
登録日2016-06-14
公開日2017-07-12
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus.
Virology, 533, 2019
6PSN
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BU of 6psn by Molmil
Anthrax toxin protective antigen channels bound to lethal factor
分子名称: CALCIUM ION, Lethal factor, Protective antigen
著者Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A.
登録日2019-07-12
公開日2020-03-04
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors.
Nat Commun, 11, 2020
5LAK
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BU of 5lak by Molmil
Ligand-bound structure of Cavally Virus 3CL Protease
分子名称: 3Cl Protease, BEZ-TYR-TYR-ASN-ECC Peptide inhibitor, PENTAETHYLENE GLYCOL, ...
著者Kanitz, M, Heine, A, Diederich, W.E.
登録日2016-06-14
公開日2017-07-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献Structural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus.
Virology, 533, 2019
6CSL
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BU of 6csl by Molmil
Pneumococcal PhtD protein 269-339 fragment with bound Zn(II)
分子名称: Histidine triad protein D, ZINC ION
著者Luo, Z, Pederick, V.G, Paton, J.C, McDevitt, C.A, Kobe, B.
登録日2018-03-20
公開日2018-06-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.921 Å)
主引用文献Structural characterisation of the HT3 motif of the polyhistidine triad protein D from Streptococcus pneumoniae.
FEBS Lett., 592, 2018
6VRA
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BU of 6vra by Molmil
Anthrax octamer prechannel bound to full-length edema factor
分子名称: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen
著者Zhou, K, Hardenbrook, N.J, Liu, S, Cui, Y.X, Krantz, B.A, Zhou, Z.H.
登録日2020-02-07
公開日2020-12-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Atomic Structures of Anthrax Prechannel Bound with Full-Length Lethal and Edema Factors.
Structure, 28, 2020
6BHW
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BU of 6bhw by Molmil
B. subtilis SsbA
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Single-stranded DNA-binding protein A
著者Dubiel, K.D, Myers, A.R, Satyshur, K.A, Keck, J.L.
登録日2017-10-31
公開日2018-12-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.208 Å)
主引用文献Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins.
J. Mol. Biol., 431, 2019
5ULC
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BU of 5ulc by Molmil
PLASMODIUM FALCIPARUM BROMODOMAIN-CONTAINING PROTEIN PF10_0328
分子名称: Bromodomain protein 1
著者Wernimont, A.K, Amaya, M.F, Lam, A, Ali, A, Zhang, A.Z, Kenzina, L, Lin, Y.H, MacKenzie, F, Kozieradzki, I, Cossar, D, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Weigelt, J, Hui, R, Walker, J.R, Qiu, W, Brand, V, Structural Genomics Consortium (SGC)
登録日2017-01-24
公開日2017-02-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献PLASMODIUM FALCIPARUM BROMODOMAIN-CONTAINING PROTEIN PF10_0328
To be published
8CB1
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BU of 8cb1 by Molmil
Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with N-PNT-DNM 15
分子名称: (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Sulzenbacher, G, Roig-Zamboni, V, Overkleeft, H, Artola, M.
登録日2023-01-25
公開日2023-09-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases.
Chem Sci, 14, 2023
8CB6
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BU of 8cb6 by Molmil
Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in covalent complex with TAMRA tagged 1,6-Epi-cylcophellitol aziridine activity based probe
分子名称: (1S,2R,3R,4R,5R)-5-[8-[4-(4-azanylbutyl)-1,2,3-triazol-1-yl]octylamino]-4-(hydroxymethyl)cyclohexane-1,2,3-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Sulzenbacher, G, Roig-Zamboni, V, Overkleeft, H, Artola, M.
登録日2023-01-25
公開日2023-09-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases.
Chem Sci, 14, 2023
5JD5
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BU of 5jd5 by Molmil
Crystal structure of MGS-MilE3, an alpha/beta hydrolase enzyme from the metagenome of pyrene-phenanthrene enrichment culture with sediment sample of Milazzo Harbor, Italy
分子名称: CHLORIDE ION, MGS-MilE3
著者Stogios, P.J, Xu, X, Cui, H, Martinez-Martinez, M, Chernikova, T.N, Golyshin, P.N, Yakimov, M.M, Ferrer, M, Savchenko, A.
登録日2016-04-15
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of MGS-MilE3, an alpha/beta hydrolase enzyme from the metagenome of pyrene-phenanthrene enrichment culture with sediment sample of Milazzo Harbor, Italy
To Be Published
6WJJ
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BU of 6wjj by Molmil
Anthrax octamer prechannel bound to full-length lethal factor
分子名称: CALCIUM ION, Lethal factor, Protective antigen, ...
著者Zhou, K, Hardenbrook, N.J, Liu, S, Cui, Y.X, Krantz, B.A, Zhou, Z.H.
登録日2020-04-13
公開日2020-12-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Atomic Structures of Anthrax Prechannel Bound with Full-Length Lethal and Edema Factors.
Structure, 28, 2020
5MM8
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BU of 5mm8 by Molmil
Atomic resolution structure of SplE protease from Staphylococcus aureus
分子名称: ACETATE ION, Serine protease SplE
著者Stach, N, Zdzalik, M, Dubin, G.
登録日2016-12-08
公開日2018-03-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Unique Substrate Specificity of SplE Serine Protease from Staphylococcus aureus.
Structure, 26, 2018
4WBT
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BU of 4wbt by Molmil
Crystal structure of histidinol-phosphate aminotransferase from Sinorhizobium meliloti in complex with pyridoxal-5'-phosphate
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Shabalin, I.G, Bacal, P, Kowalska, A.K, Cooper, D.R, Stead, M, Hammonds, J, Ahmed, M, Hillerich, B.S, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
登録日2014-09-03
公開日2014-09-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of histidinol-phosphate aminotransferase from Sinorhizobium meliloti in complex with pyridoxal-5'-phosphate
to be published
4WCZ
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BU of 4wcz by Molmil
Crystal structure of a putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans
分子名称: Enoyl-CoA hydratase/isomerase
著者Tkaczuk, K.L, Cooper, D.R, Chapman, H.C, Niedzialkowska, E, Cymborowski, M.T, Hillerich, B.S, Stead, M, Ahmed, M, Hammonds, J, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
登録日2014-09-05
公開日2014-12-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal structure of a putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans
to be published
4QT6
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BU of 4qt6 by Molmil
Crystal structure of the SPRY domain of human HERC1
分子名称: FORMAMIDE, Probable E3 ubiquitin-protein ligase HERC1, UNKNOWN ATOM OR ION
著者Dong, A, Hu, J, Guan, X, Wernimont, A, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
登録日2014-07-07
公開日2015-01-07
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Crystal structure of the SPRY domain of human HERC1
To be Published
4RD8
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BU of 4rd8 by Molmil
The crystal structure of a functionally-unknown protein from Legionella pneumophila subsp. pneumophila str. Philadelphia 1
分子名称: Uncharacterized protein
著者Tan, K, Xu, X, Cui, H, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2014-09-18
公開日2014-10-01
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献The crystal structure of a functionally-unknown protein from Legionella pneumophila subsp. pneumophila str. Philadelphia 1
To be Published
4X2P
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BU of 4x2p by Molmil
P. putida mandelate racemase in complex with 3-hydroxypyruvate
分子名称: 3-HYDROXYPYRUVIC ACID, MAGNESIUM ION, Mandelate racemase
著者Wyatt, B.N, St.Maurice, M.
登録日2014-11-26
公開日2015-10-14
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Inactivation of Mandelate Racemase by 3-Hydroxypyruvate Reveals a Potential Mechanistic Link between Enzyme Superfamilies.
Biochemistry, 54, 2015

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件を2024-10-02に公開中

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