PDB: 45853 件ウェブページステータス検索Chemie searchBIRD

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4UXI	Leishmania major Thymidine Kinase in complex with thymidine 分子名称: PHOSPHATE ION, THYMIDINE, THYMIDINE KINASE, ... 著者 Timm, J, Bosch-Navarrete, C, Recio, E, Nettleship, J.E, Rada, H, Gonzalez-Pacanowska, D, Wilson, K.S. 登録日 2014-08-22 公開日 2015-05-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Structural and Kinetic Characterization of Thymidine Kinase from Leishmania Major. Plos Negl Trop Dis, 9, 2015
4W5B	Crystal structure analysis of cruzain with Fragment 1 (N-(1H-benzimidazol-2-yl)-1,3-dimethyl-pyrazole-4-carboxamide) 分子名称: Cruzipain, N-(1H-benzimidazol-2-yl)-1,3-dimethyl-1H-pyrazole-4-carboxamide 著者 Tochowicz, A, McKerrow, J.H, Craik, C.S. 登録日 2014-08-17 公開日 2015-03-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.701 Å) 主引用文献 Applying Fragments Based- Drug Design to identify multiple binding modes on cysteine protease. To Be Published
4WHK	A New Class of Peptidomimetics Targeting the Polo-box Domain of Polo-like kinase 1 分子名称: C6H5(CH2)8-DERIVATIZED PEPTIDE INHIBITOR, Serine/threonine-protein kinase PLK1 著者 Bang, J.K, Han, Y.H, Ahn, M.J, Lee, K.S. 登録日 2014-09-23 公開日 2014-12-03 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A new class of peptidomimetics targeting the polo-box domain of polo-like kinase 1. J.Med.Chem., 58, 2015
4WJM	Crystal structure of Fructokinase from Brucella abortus 2308 with bound AMPPNP 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, MALONIC ACID, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-10-01 公開日 2014-10-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of Fructokinase from Brucella abortus 2308 with bound AMPPNP To Be Published
4WFR	Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation T232A, complexed with 2'-AMP 分子名称: 2',3'-cyclic-nucleotide 3'-phosphodiesterase, ADENOSINE-2'-MONOPHOSPHATE 著者 Myllykoski, M, Raasakka, A, Kursula, P. 登録日 2014-09-17 公開日 2015-09-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase. Sci Rep, 5, 2015
4WJG	Structure of T. brucei haptoglobin-hemoglobin receptor binding to human haptoglobin-hemoglobin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Haptoglobin, ... 著者 Stoedkilde, K, Torvund-Jensen, M, Moestrup, S.K, Andersen, C.B.F. 登録日 2014-09-30 公開日 2014-11-26 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis for trypanosomal haem acquisition and susceptibility to the host innate immune system. Nat Commun, 5, 2014
4WNY	Crystal structure of a protein from the universal stress protein family from Burkholderia pseudomallei 分子名称: Universal stress protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-10-14 公開日 2014-11-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of a protein from the universal stress protein family from Burkholderia pseudomallei to be published
4WX5	pore-forming thermostable direct hemolysin from Grimontia hollisae 分子名称: Hemolysin, heat labile 著者 Wang, Y.-K, Wu, T.-K, Li, T.-H.T. 登録日 2014-11-13 公開日 2015-11-18 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Multiple pleomorphic tetramers of pore-forming thermostable direct hemolysin from Grimontia hollisae in exerting membrane binding and hemolytic activity To be published
4WWS	Structure of Chlorite dismutase-like Protein from Listeria monocytogenes 分子名称: POTASSIUM ION, Putative heme-dependent peroxidase lmo2113 著者 Hagmueller, A, Mlynek, G, Djinovic-Carugo, K. 登録日 2014-11-12 公開日 2015-02-04 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and heme-binding properties of HemQ (chlorite dismutase-like protein) from Listeria monocytogenes. Arch.Biochem.Biophys., 574, 2015
4WXY	PLPS (inactive glutaminase mutant) co-crystallized with glutamine and R5P. 分子名称: Glutamine amidotransferase subunit PdxT, Pyridoxal biosynthesis lyase PdxS 著者 Smith, J.L, Smith, A.M. 登録日 2014-11-14 公開日 2015-01-14 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structures capture three states in the catalytic cycle of a pyridoxal phosphate (PLP) synthase. J.Biol.Chem., 290, 2015
4WEX	Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation Y168S 分子名称: 2',3'-cyclic-nucleotide 3'-phosphodiesterase, CHLORIDE ION 著者 Myllykoski, M, Raasakka, A, Kursula, P. 登録日 2014-09-11 公開日 2015-09-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase. Sci Rep, 5, 2015
4X7N	Co-crystal Structure of PERK bound to 4-[2-amino-4-methyl-3-(2-methylquinolin-6-yl)benzoyl]-1-methyl-2,5-diphenyl-1,2-dihydro-3H-pyrazol-3-one inhibitor 分子名称: 4-[2-amino-4-methyl-3-(2-methylquinolin-6-yl)benzoyl]-1-methyl-2,5-diphenyl-1,2-dihydro-3H-pyrazol-3-one, Eukaryotic translation initiation factor 2-alpha kinase 3,Eukaryotic translation initiation factor 2-alpha kinase 3, L(+)-TARTARIC ACID 著者 Shaffer, P.L, Long, A.M, Chen, H. 登録日 2014-12-09 公開日 2015-01-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Discovery of 1H-Pyrazol-3(2H)-ones as Potent and Selective Inhibitors of Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK). J.Med.Chem., 58, 2015
4WH0	YcaC from Pseudomonas aeruginosa with S-mercaptocysteine active site cysteine 分子名称: CHLORIDE ION, Putative hydrolase 著者 Groftehauge, M.K, Truan, D, Vasil, A, Denny, P.W, Vasil, M.L, Pohl, E. 登録日 2014-09-19 公開日 2015-07-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.563 Å) 主引用文献 Crystal Structure of a Hidden Protein, YcaC, a Putative Cysteine Hydrolase from Pseudomonas aeruginosa, with and without an Acrylamide Adduct. Int J Mol Sci, 16, 2015
4WL0	Ligand-free structure of human platelet phosphofructokinase in an R-state, crystal form I 分子名称: ATP-dependent 6-phosphofructokinase, platelet type, PHOSPHATE ION 著者 Kloos, M, Strater, N. 登録日 2014-10-05 公開日 2015-06-03 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation. Biochem.J., 469, 2015
4X7J	Co-crystal Structure of PERK with 2-amino-N-[4-methoxy-3-(trifluoromethyl)phenyl]-4-methyl-3-[2-(methylamino)quinazolin-6-yl]benzamide inhibitor 分子名称: 2-amino-N-[4-methoxy-3-(trifluoromethyl)phenyl]-4-methyl-3-[2-(methylamino)quinazolin-6-yl]benzamide, Eukaryotic translation initiation factor 2-alpha kinase 3,Eukaryotic translation initiation factor 2-alpha kinase 3, L(+)-TARTARIC ACID 著者 Shaffer, P.L, Long, A.M, Chen, H. 登録日 2014-12-09 公開日 2015-01-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Discovery of 1H-Pyrazol-3(2H)-ones as Potent and Selective Inhibitors of Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK). J.Med.Chem., 58, 2015
4X7P	Crystal structure of apo S. aureus TarM 分子名称: SULFATE ION, TarM 著者 Worrall, L.J, Sobhanifar, S, Gruninger, R.J, Strynadka, N.C. 登録日 2014-12-09 公開日 2015-02-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase. Proc.Natl.Acad.Sci.USA, 112, 2015
4WXR	X-ray crystal structure of NS3 Helicase from HCV with a bound inhibitor at 2.42 A resolution 分子名称: NS3, {6-(3,5-diaminophenyl)-1-[4-(propan-2-yl)benzyl]-1H-indol-3-yl}acetic acid 著者 Davies, D.R, Kim, H, Lorimer, D. 登録日 2014-11-14 公開日 2015-12-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 crystal structure of NS3 Helicase from HCV with a bound inhibitor TO BE PUBLISHED
4WQO	Structure of VHL-EloB-EloC-Cul2 分子名称: Cullin-2, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, ... 著者 Nguyen, H.C, Xiong, Y. 登録日 2014-10-22 公開日 2015-03-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Insights into Cullin-RING E3 Ubiquitin Ligase Recruitment: Structure of the VHL-EloBC-Cul2 Complex. Structure, 23, 2015
4WW1	Crystal structure of human TCR Alpha Chain-TRAV21-TRAJ8 and Beta Chain-TRBV7-8 分子名称: TCR Alpha Chain-TRAV21-TRAJ8, TCR Beta Chain-TRBV7-8 著者 Le Nours, J, Praveena, T, Pellicci, D.G, Lim, R.T, Besra, G, Howell, A.R, Godfrey, D.I, Rossjohn, J, Uldrich, A.P. 登録日 2014-11-10 公開日 2016-02-03 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens. Nat Commun, 7, 2016
4X7K	Co-crystal Structure of PERK bound to 4-{2-amino-3-[5-fluoro-2-(methylamino)quinazolin-6-yl]-4-methylbenzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3H-pyrazol-3-one inhibitor 分子名称: 4-{2-amino-3-[5-fluoro-2-(methylamino)quinazolin-6-yl]-4-methylbenzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3H-pyrazol-3-one, Eukaryotic translation initiation factor 2-alpha kinase 3,Eukaryotic translation initiation factor 2-alpha kinase 3, GLYCEROL, ... 著者 Shaffer, P.L, Long, A.M, Chen, H. 登録日 2014-12-09 公開日 2015-01-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of 1H-Pyrazol-3(2H)-ones as Potent and Selective Inhibitors of Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK). J.Med.Chem., 58, 2015
4X2W	Crystal structure of the Murine Norovirus NS6 protease (inactive C139A mutant) with a C-terminal extension to include residues P1 prime - P2 prime of NS7 分子名称: NS6 Protease 著者 Fernandes, H, Leen, E.N, Curry, S. 登録日 2014-11-27 公開日 2015-02-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease-substrate interactions. Peerj, 3, 2015
4X3S	Crystal structure of chromobox homology 7 (CBX7) with SETDB1-1170me3 Peptide 分子名称: CITRIC ACID, Chromobox protein homolog 7, FE (III) ION, ... 著者 Ren, C, Plotnikov, A.N, Zhou, M.M. 登録日 2014-12-01 公開日 2015-03-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain. Chem.Biol., 22, 2015
4WPE	Crystal Structure of Hof1p F-BAR domain 分子名称: Cytokinesis protein 2 著者 Lemmon, M.A, Moravcevic, K. 登録日 2014-10-17 公開日 2014-12-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Comparison of Saccharomyces cerevisiae F-BAR Domain Structures Reveals a Conserved Inositol Phosphate Binding Site. Structure, 23, 2015
4WN3	Crystal structure of Saccharomyces cerevisiae OMP synthase in complex with PRP(NH)P 分子名称: MAGNESIUM ION, Orotate phosphoribosyltransferase 1, [[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]oxy-oxidanyl-phosphoryl]amino]phosphonic acid 著者 Bang, M.B, Molich, U, Hansen, M.R, Grubmeyer, C, Harris, P. 登録日 2014-10-10 公開日 2015-12-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Saccharomyces cerevisiae OMP synthase in complex with PRP(NH)P To Be Published
4X92	Crystal structure of Lysosomal Phospholipase A2-S165A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Group XV phospholipase A2 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-11 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015

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