PDB: 1139 件ウェブページステータス検索Chemie searchBIRD

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7R49	Crystal structure of the L. plantarum acyl carrier protein synthase (AcpS)in complex with D-alanyl carrier protein (DltC1) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4'-PHOSPHOPANTETHEINE, D-alanyl carrier protein 1, ... 著者 Nikolopoulos, N, Ravaud, S, Simorre, J.P, Grangeasse, C. 登録日 2022-02-08 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 DltC acts as an interaction hub for AcpS, DltA and DltB in the teichoic acid D-alanylation pathway of Lactiplantibacillus plantarum. Sci Rep, 12, 2022
3EUO	crystal structure of a fungal type III polyketide synthase, ORAS 分子名称: Type III Pentaketide Synthase 著者 Zhang, H, Brunzelle, J.S, Nair, S.K. 登録日 2008-10-10 公開日 2008-11-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Distinct Structural Elements Dictate the Specificity of the Type III Pentaketide Synthase from Neurospora crassa. Chem.Biol., 15, 2008
3OYT	1.84 Angstrom resolution crystal structure of 3-oxoacyl-(acyl carrier protein) synthase I (fabB) from Yersinia pestis CO92 分子名称: 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier-protein] synthase I, DI(HYDROXYETHYL)ETHER, ... 著者 Halavaty, A.S, Wawrzak, Z, Onopriyenko, O, Peterson, S, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-09-23 公開日 2011-01-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 1.84 Angstrom resolution crystal structure of 3-oxoacyl-(acyl carrier protein) synthase I (fabB) from Yersinia pestis CO92 To be Published
6HXO	Structure of the citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase (space group P21) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ATP-citrate lyase alpha-subunit, CITRATE ANION 著者 Verstraete, K, Verschueren, K. 登録日 2018-10-17 公開日 2019-04-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
2WYA	CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL 3-HYDROXY-3-METHYLGLUTARYL- COENZYME A SYNTHASE 2 (HMGCS2) 分子名称: 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, GLYCEROL, HYDROXYMETHYLGLUTARYL-COA SYNTHASE, ... 著者 Yue, W.W, Shafqat, N, Savitsky, P, Roos, A.K, Cooper, C, Murray, J.W, von Delft, F, Arrowsmith, C, Wikstrom, M, Edwards, A, Bountra, C, Oppermann, U. 登録日 2009-11-13 公開日 2009-11-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structures of Human Hmg-Coa Synthase Isoforms Provide Insights Into Inherited Ketogenesis Disorders and Inhibitor Design. J.Mol.Biol., 398, 2010
5KP2	Beta-ketoacyl-ACP synthase III -2 (FabH2) (C113A) from Vibrio Cholerae cocrystallized with octanoyl-CoA: hydrolzed ligand 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2, COENZYME A, OCTANOIC ACID (CAPRYLIC ACID) 著者 Hou, J, Zheng, H, Grabowski, M, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2016-07-01 公開日 2016-07-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Beta-ketoacyl-ACP synthase III -2 (FabH2) (C113A) from Vibrio Cholerae soaked with octanoyl-CoA: hydrolzed ligand To Be Published
6QFB	Structure of the human ATP citrate lyase holoenzyme in complex with citrate, coenzyme A and Mg.ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, CITRATE ANION, ... 著者 Verstraete, K, Verschueren, K. 登録日 2019-01-09 公開日 2019-04-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
4NA1	Crystal Structure of the second ketosynthase from the bacillaene polyketide synthase 分子名称: Polyketide synthase PksJ, SULFATE ION 著者 Gay, D.C, Gay, G.R, Keatinge-Clay, A.T. 登録日 2013-10-21 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase. Structure, 22, 2014
2X2B	Crystal structure of malonyl-ACP (acyl carrier protein) from Bacillus subtilis 分子名称: 3-{[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-3-oxopropanoic acid, ACYL CARRIER PROTEIN, PLATINUM (II) ION 著者 Bellinzoni, M, Martinez, M.A, DeMendoza, D, Alzari, P.M. 登録日 2010-01-12 公開日 2010-03-16 最終更新日 2011-10-12 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 A Novel Role of Malonyl-Acp in Lipid Homeostasis. Biochemistry, 49, 2010
6C9U	Crystal structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase in complex with antibody fragment (Fab) 分子名称: 6-deoxyerythronolide-B synthase EryA2, modules 3 and 4, Heavy chain of Fab 1B2, ... 著者 Deis, L.N, Li, X, Mathews, I.I, Khosla, C. 登録日 2018-01-28 公開日 2018-05-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module. J. Am. Chem. Soc., 140, 2018
6DGJ	Cronobacter turicensis RpfR quorum-sensing receptor PAS domain in complex with BDSF 分子名称: (2Z)-dodec-2-enoic acid, RpfR 著者 Waldron, E.J, Neiditch, M.B. 登録日 2018-05-17 公開日 2019-01-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.294 Å) 主引用文献 Structural basis of DSF recognition by its receptor RpfR and its regulatory interaction with the DSF synthase RpfF. PLoS Biol., 17, 2019
5W8C	The structure of a COA-dependent acyl-homoserine lactone synthase, BjaI, with MTA and isovaleryl-CoA 分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, Autoinducer synthase, CHLORIDE ION, ... 著者 Dong, S.-H, Nair, S.K. 登録日 2017-06-21 公開日 2017-08-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Molecular basis for the substrate specificity of quorum signal synthases. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W8D	The structure of a COA-dependent acyl-homoserine lactone synthase, BjaI, with MTA 分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, Autoinducer synthase, GLYCEROL 著者 Dong, S.-H, Nair, S.K. 登録日 2017-06-21 公開日 2017-08-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis for the substrate specificity of quorum signal synthases. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6DGG	Cronobacter turicensis RpfR quorum-sensing receptor PAS domain in complex with C12:0 分子名称: LAURIC ACID, RpfR 著者 Waldron, E.J, Neiditch, M.B. 登録日 2018-05-17 公開日 2019-01-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.498 Å) 主引用文献 Structural basis of DSF recognition by its receptor RpfR and its regulatory interaction with the DSF synthase RpfF. PLoS Biol., 17, 2019
5W8A	The structure of a COA-dependent acyl-homoserine lactone synthase, BjaI, with SAM and isopentyl-CoA 分子名称: Autoinducer synthase, S-ADENOSYLMETHIONINE, isopentyl-Coenzyme A 著者 Dong, S.-H, Nair, S.K. 登録日 2017-06-21 公開日 2017-08-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis for the substrate specificity of quorum signal synthases. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W8G	The structure of a COA-dependent acyl-homoserine lactone synthase, BjaI, with SAH 分子名称: Autoinducer synthase, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION 著者 Dong, S.-H, Nair, S.K. 登録日 2017-06-21 公開日 2017-08-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis for the substrate specificity of quorum signal synthases. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3IL5	Structure of E. faecalis FabH in complex with 2-({4-bromo-3-[(diethylamino)sulfonyl]benzoyl}amino)benzoic acid 分子名称: 2-({[4-bromo-3-(diethylsulfamoyl)phenyl]carbonyl}amino)benzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 3 著者 Gajiwala, K.S, Margosiak, S, Lu, J, Cortez, J, Su, Y, Nie, Z, Appelt, K. 登録日 2009-08-06 公開日 2009-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structures of bacterial FabH suggest a molecular basis for the substrate specificity of the enzyme. Febs Lett., 583, 2009
6FIJ	Structure of the loading/condensing region (SAT-KS-MAT) of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, ... 著者 Herbst, D.A, Jakob, R.P, Townsend, C.A, Maier, T. 登録日 2018-01-18 公開日 2018-03-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 The structural organization of substrate loading in iterative polyketide synthases. Nat. Chem. Biol., 14, 2018
3IL6	Structure of E. faecalis FabH in complex with 2-({4-[(3R,5S)-3,5-dimethylpiperidin-1-yl]-3-phenoxybenzoyl}amino)benzoic acid 分子名称: 2-[({4-[(3R,5S)-3,5-dimethylpiperidin-1-yl]-3-phenoxyphenyl}carbonyl)amino]benzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 3, SULFATE ION 著者 Gajiwala, K.S, Margosiak, S, Lu, J, Cortez, J, Su, Y, Nie, Z, Appelt, K. 登録日 2009-08-06 公開日 2009-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of bacterial FabH suggest a molecular basis for the substrate specificity of the enzyme. Febs Lett., 583, 2009
1TPY	Structure of the cyclopropane synthase MmaA2 from Mycobacterium tuberculosis 分子名称: CARBONATE ION, CETYL-TRIMETHYL-AMMONIUM, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Smith, C.V, Sacchettini, J.C. 登録日 2004-06-16 公開日 2004-10-19 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the cyclopropane synthase MmaA2 from Mycobacterium tuberculosis To be Published
7CQT	Crystal structure of Brassica juncea HMG-CoA synthase 1 mutant - S359A in complex with acetyl-CoA 分子名称: 3-hydroxy-3-methylglutaryl coenzyme A synthase, ACETYL COENZYME *A, ADENOSINE-3'-5'-DIPHOSPHATE 著者 Liao, P, Hu, M, Kong, G.K.W, Hao, Q, Chye, M.L. 登録日 2020-08-11 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Overexpression and Inhibition of 3-Hydroxy-3-Methylglutaryl-CoA Synthase Affect Central Metabolic Pathways in Tobacco. Plant Cell.Physiol., 62, 2021
2BYD	Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase 分子名称: BROMIDE ION, HSPC223 著者 Bunkoczi, G, Wu, X, Dubinina, E, Johansson, C, Smee, C, Turnbull, A, Oppermann, U, von Delft, F, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J. 登録日 2005-07-29 公開日 2005-08-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Mechanism and substrate recognition of human holo ACP synthase. Chem. Biol., 14, 2007
2C43	STRUCTURE OF AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE- PHOSPHOPANTETHEINYL TRANSFERASE IN COMPLEX WITH COENZYME A 分子名称: AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE, CHLORIDE ION, COENZYME A, ... 著者 Bunkoczi, G, Wu, X, Dubinina, E, Johansson, C, Smee, C, Turnbull, A, von Delft, F, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Oppermann, U. 登録日 2005-10-14 公開日 2005-10-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Mechanism and substrate recognition of human holo ACP synthase. Chem. Biol., 14, 2007
7CB3	Crystal structure of type III polyketide synthase from Mycobacterium marinum 分子名称: ACETATE ION, Chalcone/stilbene synthase, MYRISTIC ACID, ... 著者 Pratap, S, Kant, A, Saxena, P, Krishnan, V. 登録日 2020-06-10 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Crystal structure of type III polyketide synthase from Mycobacterium marinum. To Be Published
2EFT	Methanethiol-CYS 112 inhibition complex of E. coli ketoacyl synthase III (FABH) and Coenzyme A (high concentration (1.7mM) soak) 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 3, COENZYME A, METHANETHIOL, ... 著者 Alhamadsheh, M.M, Musayev, F, Komissarov, A.A, Sachdeva, S, Wright, H.T, Scarsdale, N, Florova, G, Reynolds, K.A. 登録日 2007-02-24 公開日 2007-06-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Alkyl-CoA Disulfides as Inhibitors and Mechanistic Probes for FabH Enzymes Chem.Biol., 14, 2007

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