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4YWP
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BU of 4ywp by Molmil
Sucrose Binding Site in genetically engineered Carbonic anhydrase IX
分子名称: Carbonic anhydrase 2, ZINC ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
著者Pinard, M.A, Aggarwal, M.
登録日2015-03-20
公開日2015-10-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献A sucrose-binding site provides a lead towards an isoform-specific inhibitor of the cancer-associated enzyme carbonic anhydrase IX.
Acta Crystallogr F Struct Biol Commun, 71, 2015
7PRI
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BU of 7pri by Molmil
Carbonic Anhydrase from Schistosoma Mansoni in complex with clorsulon
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-azanyl-6-[1,2,2-tris(chloranyl)ethenyl]benzene-1,3-disulfonamide, Carbonic anhydrase, ...
著者Angeli, A, Ferraroni, M.
登録日2021-09-21
公開日2022-10-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.679 Å)
主引用文献Inhibition of Schistosoma mansoni carbonic anhydrase by the antiparasitic drug clorsulon: X-ray crystallographic and in vitro studies.
Acta Crystallogr D Struct Biol, 78, 2022
1DDZ
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BU of 1ddz by Molmil
X-RAY STRUCTURE OF A BETA-CARBONIC ANHYDRASE FROM THE RED ALGA, PORPHYRIDIUM PURPUREUM R-1
分子名称: CARBONIC ANHYDRASE, ZINC ION
著者Mitsuhashi, S, Mizushima, T, Yamashita, E, Miyachi, S, Tsukihara, T.
登録日1999-11-12
公開日2000-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray structure of beta-carbonic anhydrase from the red alga, Porphyridium purpureum, reveals a novel catalytic site for CO(2) hydration.
J.Biol.Chem., 275, 2000
3S78
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BU of 3s78 by Molmil
The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
分子名称: Carbonic anhydrase 2, ZINC ION, thiophene-2-sulfonamide
著者Snyder, P.W, Heroux, A, Whitesides, G.W.
登録日2011-05-26
公開日2011-10-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase.
Proc.Natl.Acad.Sci.USA, 108, 2011
7P1A
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BU of 7p1a by Molmil
Carbonic Anhydrase VII Sultam Based Inhibitors
分子名称: 4-[2-[4-[(4-methylphenyl)methyl]-1,1-bis(oxidanylidene)-1,2,4-thiadiazinan-2-yl]ethyl]benzenesulfonamide, Carbonic anhydrase 7, GLYCEROL, ...
著者D'Ambrosio, K, De Simone, G.
登録日2021-07-01
公開日2021-11-17
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Sultam based Carbonic Anhydrase VII inhibitors for the management of neuropathic pain.
Eur.J.Med.Chem., 227, 2021
3S75
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BU of 3s75 by Molmil
The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase
分子名称: Carbonic anhydrase 2, ZINC ION, furan-2-sulfonamide
著者Snyder, P.W, Heroux, A, Whitesides, G.W.
登録日2011-05-26
公開日2011-10-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase.
Proc.Natl.Acad.Sci.USA, 108, 2011
6LUW
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BU of 6luw by Molmil
Zn- Carbonic Anhydrase II pH 7.8 0 atm CO2
分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION
著者Kim, C.U, Kim, J.K.
登録日2020-02-02
公開日2020-08-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Elucidating the role of metal ions in carbonic anhydrase catalysis.
Nat Commun, 11, 2020
6LV7
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BU of 6lv7 by Molmil
Ni- Carbonic Anhydrase II pH 11.0 0 atm CO2
分子名称: Carbonic anhydrase 2, GLYCEROL, NICKEL (II) ION
著者Kim, C.U, Kim, J.K.
登録日2020-02-02
公開日2020-08-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Elucidating the role of metal ions in carbonic anhydrase catalysis.
Nat Commun, 11, 2020
6LUU
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BU of 6luu by Molmil
apo- Carbonic Anhydrase II pH 7.8 0 atm CO2
分子名称: Carbonic anhydrase 2, GLYCEROL
著者Kim, C.U, Kim, J.K.
登録日2020-02-02
公開日2020-08-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Elucidating the role of metal ions in carbonic anhydrase catalysis.
Nat Commun, 11, 2020
6LUY
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BU of 6luy by Molmil
Zn- Carbonic Anhydrase II pH 11.0 0 atm CO2
分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION
著者Kim, C.U, Kim, J.K.
登録日2020-02-02
公開日2020-08-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Elucidating the role of metal ions in carbonic anhydrase catalysis.
Nat Commun, 11, 2020
6LV5
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BU of 6lv5 by Molmil
Ni- Carbonic Anhydrase II pH 7.8 0 atm CO2
分子名称: Carbonic anhydrase 2, GLYCEROL, NICKEL (II) ION
著者Kim, C.U, Kim, J.K.
登録日2020-02-02
公開日2020-08-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Elucidating the role of metal ions in carbonic anhydrase catalysis.
Nat Commun, 11, 2020
3RG3
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BU of 3rg3 by Molmil
Crystal structure of the W5E mutant of human carbonic anhydrase II
分子名称: Carbonic anhydrase 2, ZINC ION
著者Domsic, J.F, Robbins, A.H, McKenna, R.
登録日2011-04-07
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5.
Arch.Biochem.Biophys., 516, 2011
3RG4
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BU of 3rg4 by Molmil
Crystal structure of the W5F mutant of human carbonic anhydrase II
分子名称: Carbonic anhydrase 2, ZINC ION
著者Domsic, J.F, Robbins, A.H, McKenna, R.
登録日2011-04-07
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5.
Arch.Biochem.Biophys., 516, 2011
3RGE
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BU of 3rge by Molmil
Crystal structure of the W5H mutant of human carbonic anhydrase II
分子名称: Carbonic anhydrase 2, ZINC ION
著者Domsic, J.F, Robbins, A.H, McKenna, R.
登録日2011-04-08
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.096 Å)
主引用文献Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5.
Arch.Biochem.Biophys., 516, 2011
6GWU
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BU of 6gwu by Molmil
Carbonic anhydrase CaNce103p from Candida albicans
分子名称: BETA-MERCAPTOETHANOL, Carbonic anhydrase, DI(HYDROXYETHYL)ETHER, ...
著者Brynda, J, Dostal, J, Heidingsfeld, O, Machacek, S, Blaha, J, Pichova, I.
登録日2018-06-26
公開日2018-11-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of carbonic anhydrase CaNce103p from the pathogenic yeast Candida albicans.
BMC Struct. Biol., 18, 2018
3M1K
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BU of 3m1k by Molmil
Carbonic Anhydrase in complex with fragment
分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 1-hydroxy-2-sulfanylpyridinium, Carbonic anhydrase 2, ...
著者Schulze Wischeler, J, Heine, A, Klebe, G.
登録日2010-03-05
公開日2010-11-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Bidentate Zinc chelators for alpha-carbonic anhydrases that produce a trigonal bipyramidal coordination geometry.
Chemmedchem, 5, 2010
4M2W
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BU of 4m2w by Molmil
Genetically engineered Carbonic Anhydrase IX in complex with Dorzolamide
分子名称: (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, Carbonic anhydrase 2, ZINC ION
著者Pinard, M.P, Boone, C.D, Rife, B.D, Supuran, C.T, McKenna, R.
登録日2013-08-05
公開日2013-11-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.658 Å)
主引用文献Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.
Bioorg.Med.Chem., 21, 2013
2FNK
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BU of 2fnk by Molmil
Activation of Human Carbonic Anhydrase II by exogenous proton donors
分子名称: Carbonic anhydrase 2, ZINC ION
著者Bhatt, D, Fisher, S.Z, Tu, C, McKenna, R, Silverman, D.N.
登録日2006-01-11
公開日2006-11-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Location of binding sites in small molecule rescue of human carbonic anhydrase II.
Biophys.J., 92, 2007
6FE2
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BU of 6fe2 by Molmil
Three dimensional structure of human carbonic anhydrase IX
分子名称: Carbonic anhydrase 9, ZINC ION
著者Leitans, J, Tars, K.
登録日2017-12-28
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.
Oncotarget, 9, 2018
1ZNC
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BU of 1znc by Molmil
HUMAN CARBONIC ANHYDRASE IV
分子名称: CARBONIC ANHYDRASE IV, SULFATE ION, ZINC ION
著者Stams, T, Christianson, D.W.
登録日1996-09-17
公開日1997-09-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the secretory form of membrane-associated human carbonic anhydrase IV at 2.8-A resolution.
Proc.Natl.Acad.Sci.USA, 93, 1996
2CBC
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BU of 2cbc by Molmil
STRUCTURE OF NATIVE AND APO CARBONIC ANHYDRASE II AND SOME OF ITS ANION-LIGAND COMPLEXES
分子名称: CARBONIC ANHYDRASE II, FORMIC ACID, MERCURY (II) ION, ...
著者Hakansson, K, Carlsson, M, Svensson, L.A, Liljas, A.
登録日1992-06-01
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structure of native and apo carbonic anhydrase II and structure of some of its anion-ligand complexes.
J.Mol.Biol., 227, 1992
2CBB
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BU of 2cbb by Molmil
STRUCTURE OF NATIVE AND APO CARBONIC ANHYDRASE II AND SOME OF ITS ANION-LIGAND COMPLEXES
分子名称: CARBONIC ANHYDRASE II, ZINC ION
著者Hakansson, K, Carlsson, M, Svensson, L.A, Liljas, A.
登録日1992-06-01
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structure of native and apo carbonic anhydrase II and structure of some of its anion-ligand complexes.
J.Mol.Biol., 227, 1992
2CBE
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BU of 2cbe by Molmil
STRUCTURE OF NATIVE AND APO CARBONIC ANHYDRASE II AND SOME OF ITS ANION-LIGAND COMPLEXES
分子名称: CARBONIC ANHYDRASE II
著者Hakansson, K, Carlsson, M, Svensson, L.A, Liljas, A.
登録日1992-06-01
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structure of native and apo carbonic anhydrase II and structure of some of its anion-ligand complexes.
J.Mol.Biol., 227, 1992
2CBD
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BU of 2cbd by Molmil
STRUCTURE OF NATIVE AND APO CARBONIC ANHYDRASE II AND SOME OF ITS ANION-LIGAND COMPLEXES
分子名称: CARBONIC ANHYDRASE II, SULFITE ION, ZINC ION
著者Hakansson, K, Carlsson, M, Svensson, L.A, Liljas, A.
登録日1992-06-01
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structure of native and apo carbonic anhydrase II and structure of some of its anion-ligand complexes.
J.Mol.Biol., 227, 1992
2CBA
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BU of 2cba by Molmil
STRUCTURE OF NATIVE AND APO CARBONIC ANHYDRASE II AND SOME OF ITS ANION-LIGAND COMPLEXES
分子名称: CARBONIC ANHYDRASE II, ZINC ION
著者Hakansson, K, Carlsson, M, Svensson, L.A, Liljas, A.
登録日1992-06-01
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structure of native and apo carbonic anhydrase II and structure of some of its anion-ligand complexes.
J.Mol.Biol., 227, 1992

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