PDB: 1553 件ウェブページステータス検索Chemie searchBIRD

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1FLJ	CRYSTAL STRUCTURE OF S-GLUTATHIOLATED CARBONIC ANHYDRASE III 分子名称: CARBONIC ANHYDRASE III, GLUTATHIONE, ZINC ION 著者 Mallis, R.J, Poland, B.W, Chatterjee, T.K, Fisher, R.A, Darmawan, S, Honzatko, R.B, Thomas, J.A. 登録日 2000-08-14 公開日 2000-09-04 最終更新日 2017-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of S-glutathiolated carbonic anhydrase III. FEBS Lett., 482, 2000
1YO1	Proton Transfer from His200 in Human Carbonic Anhydrase II 分子名称: Carbonic anhydrase II, SULFATE ION, ZINC ION 著者 Bhatt, D, Tu, C, Fisher, S.Z, Hernandez Prada, J.A, McKenna, R, Silverman, D.N. 登録日 2005-01-26 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Proton transfer in a Thr200His mutant of human carbonic anhydrase II Proteins, 61, 2005
3DV7	Role of Hydrophilic Residues in Proton Transfer During Catalysis by Human Carbonic Anhydrase II (N62A) 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Avvaru, B.S. 登録日 2008-07-18 公開日 2008-11-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Role of hydrophilic residues in proton transfer during catalysis by human carbonic anhydrase II. Biochemistry, 47, 2008
1YO2	Proton Transfer from His200 in Human Carbonic Anhydrase II 分子名称: Carbonic anhydrase II, ZINC ION 著者 Bhatt, D, Tu, C, Fisher, S.Z, Hernandez Prada, J.A, McKenna, R, Silverman, D.N. 登録日 2005-01-26 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Proton transfer in a Thr200His mutant of human carbonic anhydrase II Proteins, 61, 2005
4E3G	Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors 分子名称: Carbonic anhydrase 2, GLYCEROL, MERCURIBENZOIC ACID, ... 著者 Cohen, S.M, Martin, D.P. 登録日 2012-03-09 公開日 2012-06-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors Chem.Commun.(Camb.), 48, 2012
4E3H	Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors 分子名称: Carbonic anhydrase 2, MERCURIBENZOIC ACID, ZINC ION, ... 著者 Cohen, S.M, Martin, D.P. 登録日 2012-03-09 公開日 2012-06-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors Chem.Commun.(Camb.), 48, 2012
4E49	Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors 分子名称: Carbonic anhydrase 2, MERCURIBENZOIC ACID, RESORCINOL, ... 著者 Cohen, S.M, Martin, D.P. 登録日 2012-03-12 公開日 2012-06-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors Chem.Commun.(Camb.), 48, 2012
4CNR	Surface residue engineering of bovine carbonic anhydrase to an extreme halophilic enzyme for potential application in postcombustion CO2 capture 分子名称: CARBONIC ANHYDRASE 2, ZINC ION 著者 Warden, A, Newman, J, Peat, T.S, Seabrook, S, Williams, M, Dojchinov, G, Haritos, V. 登録日 2014-01-24 公開日 2015-02-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Rational Engineering of a Mesohalophilic Carbonic Anhydrase to an Extreme Halotolerant Biocatalyst. Nat.Commun., 6, 2015
4CNX	Surface residue engineering of bovine carbonic anhydrase to an extreme halophilic enzyme for potential application in postcombustion CO2 capture 分子名称: CARBONIC ANHYDRASE 2, DI(HYDROXYETHYL)ETHER, ZINC ION 著者 Warden, A, Newman, J, Peat, T.S, Seabrook, S, Williams, M, Dojchinov, G, Haritos, V. 登録日 2014-01-25 公開日 2015-02-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Rational Engineering of a Mesohalophilic Carbonic Anhydrase to an Extreme Halotolerant Biocatalyst. Nat.Commun., 6, 2015
4CNV	Surface residue engineering of bovine carbonic anhydrase to an extreme halophilic enzyme for potential application in postcombustion CO2 capture 分子名称: CARBONIC ANHYDRASE 2, GLYCEROL, ZINC ION 著者 Warden, A, Newman, J, Peat, T.S, Seabrook, S, Williams, M, Dojchinov, G, Haritos, V. 登録日 2014-01-25 公開日 2015-02-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Rational Engineering of a Mesohalophilic Carbonic Anhydrase to an Extreme Halotolerant Biocatalyst. Nat.Commun., 6, 2015
1Z97	Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer. 分子名称: Carbonic anhydrase III, ZINC ION 著者 Duda, D.M, Tu, C, Fisher, S.Z, An, H, Yoshioka, C, Govindasamy, L, Laipis, P.J, Agbandje-McKenna, M, Silverman, D.N, McKenna, R. 登録日 2005-03-31 公開日 2005-08-09 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer Biochemistry, 44, 2005
1Z93	Human Carbonic Anhydrase III:Structural and Kinetic study of Catalysis and Proton Transfer. 分子名称: Carbonic anhydrase III, ZINC ION 著者 Duda, D.M, Tu, C, Fisher, S.Z, An, H, Yoshioka, C, Govindasamy, L, Laipis, P.J, Agbandje-McKenna, M, Silverman, D.N, McKenna, R. 登録日 2005-03-31 公開日 2005-08-09 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer Biochemistry, 44, 2005
3FE4	Crystal Structure of Human Carbonic Anhydrase vi 分子名称: Carbonic anhydrase 6, GLYCEROL, MAGNESIUM ION 著者 Pilka, E.S, Kochan, G, Krysztofinska, E, Muniz, J, Yue, W.W, Roos, A.K, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC) 登録日 2008-11-27 公開日 2008-12-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the secretory isozyme of mammalian carbonic anhydrases CA VI: implications for biological assembly and inhibitor development Biochem.Biophys.Res.Commun., 419, 2012
6HWZ	Selenols: a new class of Carbonic Anhydrase inhibitors 分子名称: Carbonic anhydrase 1, ZINC ION, benzeneselenol 著者 Angeli, A, Ferraroni, M. 登録日 2018-10-15 公開日 2018-12-26 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Selenols: a new class of carbonic anhydrase inhibitors. Chem. Commun. (Camb.), 55, 2019
5CXK	Crystal structure of beta carbonic anhydrase from Vibrio cholerae 分子名称: BICARBONATE ION, Carbonic anhydrase, ZINC ION 著者 Ferraroni, M, Supuran, C. 登録日 2015-07-29 公開日 2015-12-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure and kinetic studies of a tetrameric type II beta-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. Acta Crystallogr.,Sect.D, 71, 2015
6Y04	Crystal structure of beta-carbonic anhydrase isoform I (TvaCA1) from the Trichomonas vaginalis protozoan. 分子名称: Carbonic anhydrase, ZINC ION 著者 Di Fiore, A, De Simone, G. 登録日 2020-02-06 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Biochemical and structural characterisation of a protozoan beta-carbonic anhydrase fromTrichomonas vaginalis. J Enzyme Inhib Med Chem, 35, 2020
1HEB	STRUCTURAL CONSEQUENCES OF HYDROPHILIC AMINO-ACID SUBSTITUTIONS IN THE HYDROPHOBIC POCKET OF HUMAN CARBONIC ANHYDRASE II 分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION 著者 Nair, S.K, Christianson, D.W. 登録日 1992-07-16 公開日 1992-10-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural consequences of hydrophilic amino acid substitutions in the hydrophobic pocket of human carbonic anhydrase II. Biochemistry, 32, 1993
1HEC	STRUCTURAL CONSEQUENCES OF HYDROPHILIC AMINO-ACID SUBSTITUTIONS IN THE HYDROPHOBIC POCKET OF HUMAN CARBONIC ANHYDRASE II 分子名称: CARBONIC ANHYDRASE II, ZINC ION 著者 Nair, S.K, Christianson, D.W. 登録日 1992-07-16 公開日 1992-10-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural consequences of hydrophilic amino acid substitutions in the hydrophobic pocket of human carbonic anhydrase II. Biochemistry, 32, 1993
1HED	STRUCTURAL CONSEQUENCES OF HYDROPHILIC AMINO-ACID SUBSTITUTIONS IN THE HYDROPHOBIC POCKET OF HUMAN CARBONIC ANHYDRASE II 分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION 著者 Nair, S.K, Christianson, D.W. 登録日 1992-07-16 公開日 1992-10-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural consequences of hydrophilic amino acid substitutions in the hydrophobic pocket of human carbonic anhydrase II. Biochemistry, 32, 1993
5EIJ	Carbonic Anhydrase II in complex with Sulfonamide Inhibitor 分子名称: 1-(3-iodanylphenyl)-3-(4-sulfamoylphenyl)thiourea, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Lomelino, C.L, Mahon, B.P, McKenna, R. 登録日 2015-10-29 公開日 2016-11-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111. Bioorg. Med. Chem., 24, 2016
4M2W	Genetically engineered Carbonic Anhydrase IX in complex with Dorzolamide 分子名称: (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, Carbonic anhydrase 2, ZINC ION 著者 Pinard, M.P, Boone, C.D, Rife, B.D, Supuran, C.T, McKenna, R. 登録日 2013-08-05 公開日 2013-11-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.658 Å) 主引用文献 Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases. Bioorg.Med.Chem., 21, 2013
4M2V	Genetically engineered Carbonic Anhydrase IX in complex with Brinzolamide 分子名称: (+)-4-ETHYLAMINO-3,4-DIHYDRO-2-(METHOXY)PROPYL-2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE-1,1-DIOXIDE, Carbonic anhydrase 2, ZINC ION 著者 Pinard, M.P, Boone, C.D, Rife, B.D, Supuran, C.T, Mckenna, R. 登録日 2013-08-05 公開日 2013-11-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.718 Å) 主引用文献 Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases. Bioorg.Med.Chem., 21, 2013
3DAZ	Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties 分子名称: Carbonic anhydrase 2, N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide, ZINC ION 著者 Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R. 登録日 2008-05-30 公開日 2009-03-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties Biochemistry, 48, 2009
3E24	H. influenzae beta-carbonic anhydrase, variant W39F 分子名称: Carbonic anhydrase 2, PHOSPHATE ION, ZINC ION 著者 Rowlett, R.S, Lee, J. 登録日 2008-08-05 公開日 2009-06-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.301 Å) 主引用文献 Allosteric site variants of Haemophilus influenzae beta-carbonic anhydrase. Biochemistry, 48, 2009
3E3G	H. influenzae beta-carbonic anhydrase, variant G41A 分子名称: Carbonic anhydrase 2, SULFATE ION, ZINC ION 著者 Rowlett, R.S, Failing, H. 登録日 2008-08-07 公開日 2009-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Evidence for a bicarbonate "escort" site in Haemophilus influenzae beta-carbonic anhydrase . Biochemistry, 49, 2010

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