PDB: 6317 件ウェブページステータス検索Chemie searchBIRD

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2KQS	Phosphorylation of SUMO-interacting motif by CK2 enhances Daxx SUMO binding activity 分子名称: Death domain-associated protein 6, Small ubiquitin-related modifier 1 著者 Naik, M.T, Huang, T.H, Shih, H. 登録日 2009-11-17 公開日 2010-12-01 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural and functional roles of Daxx SIM phosphorylation in SUMO paralog-selective binding and apoptosis modulation. Mol.Cell, 42, 2011
5B7A	SOLUTION STRUCTURE OF LYS37 ACETYLATED HUMAN SUMO1 分子名称: Small ubiquitin-related modifier 1 著者 Naik, M.T, Naik, N, Shih, H, Huang, T. 登録日 2016-06-05 公開日 2017-06-07 最終更新日 2024-11-06 実験手法 SOLUTION NMR 主引用文献 Structures Of Human Sumo To Be Published
6H3A	Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain. 分子名称: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1, Transcription intermediary factor 1-beta, ZINC ION 著者 Newman, J.A, Aitkenhead, H, Lim, M, Williams, H.L, Svejstrup, J.Q, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2018-07-17 公開日 2019-06-26 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (5.505 Å) 主引用文献 A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin. Structure, 27, 2019
5A2Q	Structure of the HCV IRES bound to the human ribosome 分子名称: 18S RRNA, HCV IRES, MAGNESIUM ION, ... 著者 Quade, N, Leiundgut, M, Boehringer, D, Heuvel, J.v.d, Ban, N. 登録日 2015-05-21 公開日 2015-07-15 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-Em Structure of Hepatitis C Virus Ires Bound to the Human Ribosome at 3.9 Angstrom Resolution Nat.Commun., 6, 2015
7OW7	EIF6-bound large subunit of the human ribosome 分子名称: 28S rRNA, 5.8S ribosomal RNA, 5S rRNA, ... 著者 Faille, A, Warren, A.J. 登録日 2021-06-16 公開日 2022-10-05 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structure of human EIF6-bound large ribosomal subunit To Be Published
9BLN	The structure of human Pdcd4 bound to the 40S-eIF4A-eIF3-eIF1 complex 分子名称: 40S ribosomal protein S14, ACETIC ACID, Eukaryotic initiation factor 4A-I, ... 著者 Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Zuber, P, Yifei, D, Albacete-Albacete, L, Ramakrishnan, V, S Fraser, C. 登録日 2024-04-30 公開日 2024-09-04 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit. Nat Commun, 15, 2024
6AH0	The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhan, X, Yan, C, Zhang, X, Shi, Y. 登録日 2018-08-15 公開日 2018-11-14 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (5.7 Å) 主引用文献 Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell Res., 28, 2018
2LLH	NMR structure of Npm1_c70 分子名称: Nucleophosmin 著者 Banci, L, Bertini, I, Brunori, M, Di Matteo, A, Federici, L, Gallo, A, Lo Sterzo, C, Mori, M. 登録日 2011-11-09 公開日 2012-06-27 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC Promoter. J.Biol.Chem., 287, 2012
8FKR	Human nucleolar pre-60S ribosomal subunit (State B1) 分子名称: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L12, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FKZ	Human nucleolar pre-60S ribosomal subunit (State G) 分子名称: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L12, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8QFD	UFL1 E3 ligase bound 60S ribosome 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Makhlouf, L, Kulathu, Y, Zeqiraj, E. 登録日 2023-09-04 公開日 2024-02-21 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons. Nature, 627, 2024
8FKQ	Human nucleolar pre-60S ribosomal subunit (State A2) 分子名称: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L13, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8QZS	Cryo-EM structure of the cross-exon B-like complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Microfibrillar-associated protein 1, NHP2-like protein 1, ... 著者 Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. 登録日 2023-10-29 公開日 2024-05-22 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8FKP	Human nucleolar pre-60S ribosomal subunit (State A1) 分子名称: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L13, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FKS	Human nucleolar pre-60S ribosomal subunit (State B2) 分子名称: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L12, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.88 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8H6E	Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. 登録日 2022-10-17 公開日 2024-05-01 最終更新日 2025-07-16 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
8H6J	Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhang, W, Zhan, X, Zhang, X, Lei, J, Yan, C, Shi, Y. 登録日 2022-10-18 公開日 2024-05-01 最終更新日 2025-07-16 実験手法 ELECTRON MICROSCOPY (3.25 Å) 主引用文献 Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 34, 2024
9WBG	Structure of human 26S proteasome complexed with midnolin, 19S proteasome with Ubl and Catch domain resolved 分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... 著者 Zhu, C, Qin, L, Liang, L. 登録日 2025-08-14 公開日 2026-04-01 最終更新日 2026-04-08 実験手法 ELECTRON MICROSCOPY (4.23 Å) 主引用文献 Structural dynamics of the midnolin-proteasome during ubiquitin-independent substrate turnover. Nat Commun, 17, 2026
9ZE3	Cryo-EM structure of the endogenous U2/branchpoint spliceosomal complex (Distal DHX15 state) 分子名称: ATP-dependent RNA helicase DHX15, PHD finger-like domain-containing protein 5A, Pre-mRNA, ... 著者 Liu, S, Su, T, Zhou, Z.H. 登録日 2025-11-27 公開日 2026-04-15 実験手法 ELECTRON MICROSCOPY (3.93 Å) 主引用文献 The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing. Biorxiv, 2026
9ZE0	Cryo-EM structure of the endogenous U2/branchpoint spliceosomal complex (Proximal DHX15 state) 分子名称: ATP-dependent RNA helicase DHX15, PHD finger-like domain-containing protein 5A, RNA-binding protein 5, ... 著者 Liu, S, Su, T, Zhou, Z.H. 登録日 2025-11-26 公開日 2026-04-15 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing. Biorxiv, 2026
9ZEC	Cryo-EM structure of the endogenous U2/branchpoint spliceosomal complex (SF3A state 1) 分子名称: PHD finger-like domain-containing protein 5A, Pre-mRNA, RNA-binding protein 5, ... 著者 Liu, S, Su, T, Zhou, Z.H. 登録日 2025-11-29 公開日 2026-04-15 実験手法 ELECTRON MICROSCOPY (3.61 Å) 主引用文献 The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing. Biorxiv, 2026
9ZE2	Cryo-EM structure of the endogenous U2/branchpoint spliceosomal complex (core) 分子名称: PHD finger-like domain-containing protein 5A, RNA-binding protein 5, Splicing factor 3A subunit 2, ... 著者 Liu, S, Su, T, Zhou, Z.H. 登録日 2025-11-27 公開日 2026-04-15 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing. Biorxiv, 2026
9ZED	Cryo-EM structure of the endogenous U2/branchpoint spliceosomal complex (SF3A state 2) 分子名称: PHD finger-like domain-containing protein 5A, RNA-binding protein 5, Splicing factor 3A subunit 1, ... 著者 Liu, S, Su, T, Zhou, Z.H. 登録日 2025-11-29 公開日 2026-04-15 実験手法 ELECTRON MICROSCOPY (3.94 Å) 主引用文献 The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing. Biorxiv, 2026
7R4X	Cryo-EM reconstruction of the human 40S ribosomal subunit - Full map 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Pellegrino, S, Dent, K.C, Spikes, T, Warren, A.J. 登録日 2022-02-09 公開日 2023-02-22 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.15 Å) 主引用文献 Cryo-EM reconstruction of the human 40S ribosomal subunit at 2.15 angstrom resolution. Nucleic Acids Res., 51, 2023
9GMO	eIF6-bound pre-60S large ribosomal subunit incorporating mutant uL16 分子名称: 28S rRNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5.8S rRNA, ... 著者 Bothe, A, Ban, N, Kostova, K. 登録日 2024-08-29 公開日 2024-10-02 実験手法 ELECTRON MICROSCOPY (2.59 Å) 主引用文献 ZNF574 is a Quality Control Factor For Defective Ribosome Biogenesis Intermediates. Biorxiv, 2024

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