PDB: 1955 件ウェブページステータス検索Chemie searchBIRD

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7N68	The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988288 分子名称: Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, Polymerase acidic protein,Polymerase acidic protein, ... 著者 Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. 登録日 2021-06-07 公開日 2022-06-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023
7ORM	La Crosse virus polymerase at transcription early-elongation stage 分子名称: MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3'), RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*C)-3'), ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
7ORI	La Crosse virus polymerase at replication late-elongation stage 分子名称: La Crosse virus polymerase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
7ORN	La Crosse virus polymerase at replication initiation stage 分子名称: ADENOSINE-5'-TRIPHOSPHATE, La Crosse virus polymerase, MAGNESIUM ION, ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
7ORO	La Crosse virus polymerase at replication early-elongation stage 分子名称: La Crosse virus polymerase, MAGNESIUM ION, RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*C)-3'), ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
7ORL	La Crosse virus polymerase at transcription initiation stage 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, MAGNESIUM ION, PYROPHOSPHATE 2-, ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
7ORJ	La Crosse virus polymerase at transcription capped RNA cleavage stage 分子名称: 5' capped RNA, ADENOSINE-5'-TRIPHOSPHATE, RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*CP*AP*AP*G)-3'), ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
7ORK	La Crosse virus polymerase in transcription mode with cleaved capped RNA entering the polymerase active site 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (5'-D(*(GTG))-R(P*A)-3'), ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
7N5P	6218 TCR in complex with H2-Db PA224-233 with a cysteine mutant 分子名称: Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 and T-cell receptor, sp3.4 alpha chain, ... 著者 Szeto, C, Gras, S. 登録日 2021-06-06 公開日 2022-07-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus. Nat Commun, 13, 2022
7N5Q	Peptide-MHC complex of mouse H2-Db presenting PA224 with E4C mutation 分子名称: ACETATE ION, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... 著者 Szeto, C, Gras, S. 登録日 2021-06-06 公開日 2022-07-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus. Nat Commun, 13, 2022
7F0S	A crystal structure of alphavirus nonstructural protein 4 (nsP4) reveals an intrinsically 1dynamic RNA-dependent RNA polymerase 分子名称: RNA-directed RNA polymerase nsP4 著者 Tan, Y.B, Luo, D. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold. Nucleic Acids Res., 50, 2022
7N5C	6218 TCR in complex with H2Db PA with an engineered TCR-pMHC disulfide bond 分子名称: Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 with T-cell receptor, sp3.4 alpha chain, ... 著者 Szeto, C, Gras, S. 登録日 2021-06-05 公開日 2022-07-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus. Nat Commun, 13, 2022
7N4K	6218 TCR in complex with H2-Db PA 224 分子名称: Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 and T-cell receptor, sp3.4 alpha chain, ... 著者 Szeto, C, Gras, S. 登録日 2021-06-04 公開日 2022-07-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus. Nat Commun, 13, 2022
7N55	The crystal structure of the mutant I38T PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988514 分子名称: 5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-2-(2-methylphenyl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. 登録日 2021-06-04 公開日 2022-06-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023
7N47	The crystal structure of wild type PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988514 分子名称: 5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-2-(2-methylphenyl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, J.P, Rankovic, Z, White, S.W. 登録日 2021-06-03 公開日 2022-06-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023
7OPD	Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 5) 分子名称: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... 著者 Kokic, G, Cramer, P. 登録日 2021-05-31 公開日 2021-10-06 最終更新日 2021-10-27 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
7OPC	Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 4) 分子名称: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... 著者 Kokic, G, Cramer, P. 登録日 2021-05-31 公開日 2021-10-13 最終更新日 2021-10-27 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
7OOP	Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3) 分子名称: DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ... 著者 Kokic, G, Cramer, P. 登録日 2021-05-28 公開日 2021-10-06 最終更新日 2021-10-27 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
7OOB	Pol II-CSB-CSA-DDB1-UVSSA-ADPBeF3 (Structure2) 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA damage-binding protein 1, ... 著者 Kokic, G, Cramer, P. 登録日 2021-05-27 公開日 2021-10-13 最終更新日 2021-10-27 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
7OO3	Pol II-CSB-CSA-DDB1-UVSSA (Structure1) 分子名称: CSB element, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... 著者 Kokic, G, Cramer, P. 登録日 2021-05-26 公開日 2021-10-06 最終更新日 2021-10-27 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
7OMA	Thosea asigna virus RdRP domain elongation complex 分子名称: MAGNESIUM ION, PYROPHOSPHATE 2-, RNA (5'-R(P*AP*AP*AP*UP*UP*UP*U)-3'), ... 著者 Ferrero, D.S, Falqui, M, Verdaguer, N. 登録日 2021-05-21 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Snapshots of a Non-Canonical RdRP in Action. Viruses, 13, 2021
7OM9	Thosea asigna virus RdRP domain 分子名称: RNA-dependent RNA polymerase 著者 Ferrero, D.S, Falqui, M, Verdaguer, N. 登録日 2021-05-21 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Snapshots of a Non-Canonical RdRP in Action. Viruses, 13, 2021
7OM6	Thosea asigna virus RdRP domain in complex with RNA 分子名称: DI(HYDROXYETHYL)ETHER, RNA (5'-R(P*AP*AP*AP*UP*UP*U)-3'), RNA-dependent RNA polymerase 著者 Ferrero, D.S, Falqui, M, Verdaguer, N. 登録日 2021-05-21 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Snapshots of a Non-Canonical RdRP in Action. Viruses, 13, 2021
7OM7	Thosea asigna virus RdRP domain in complex with RNA and nucleotide UMPNPP 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... 著者 Ferrero, D.S, Falqui, M, Verdaguer, N. 登録日 2021-05-21 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Snapshots of a Non-Canonical RdRP in Action. Viruses, 13, 2021
7OM2	Thosea asigna virus RdRP domain in complex with Mg+2 分子名称: GLYCEROL, MAGNESIUM ION, RNA-dependent RNA polymerase, ... 著者 Ferrero, D.S, Falqui, M, Verdaguer, N. 登録日 2021-05-21 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Snapshots of a Non-Canonical RdRP in Action. Viruses, 13, 2021

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