PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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8SEI	SF Tau from Down Syndrome 分子名称: Microtubule-associated protein tau 著者 Hoq, M.R, Bharath, S.R, Jiang, W, Vago, F.S, Bharath, S.R. 登録日 2023-04-10 公開日 2024-04-03 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Cryo-EM structures of amyloid-beta and tau filaments in Down syndrome. Nat.Struct.Mol.Biol., 31, 2024
8S03	NMR solution structure of the CysD2 domain of MUC2 分子名称: CALCIUM ION, Mucin-2 著者 Recktenwald, C, Karlsson, B.G, Garcia-Bonnete, M.-J, Katona, G, Jensen, M, Lymer, R, Baeckstroem, M, Johansson, M.E.V, Hansson, G.C, Trillo-Muyo, S. 登録日 2024-02-13 公開日 2024-04-17 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based cross-linking. Cell Rep, 43, 2024
7NAF	State E2 nucleolar 60S ribosomal biogenesis intermediate - Spb1-MTD local model 分子名称: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... 著者 Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. 登録日 2021-06-21 公開日 2022-11-09 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
7N96	Crystal structure of D103A human Galectin-7 mutant 分子名称: GLYCEROL, Galectin-7 著者 Pham, N.T.H, Calmettes, C, Doucet, N. 登録日 2021-06-16 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Crystal structure of D103A human Galectin-7 mutant To Be Published
7N8D	Crystal structure of R22A human Galectin-7 mutant in presence of Lactose 分子名称: 1,2-ETHANEDIOL, Galectin-7, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose 著者 Pham, N.T.H, Calmettes, C, Doucet, N. 登録日 2021-06-14 公開日 2023-01-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Crystal structure of R22A human Galectin-7 mutant in presence of Lactose To Be Published
6EM8	S.aureus ClpC resting state, C2 symmetrised 分子名称: ATP-dependent Clp protease ATP-binding subunit ClpC 著者 Carroni, M, Mogk, A. 登録日 2017-10-01 公開日 2017-12-27 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (8.4 Å) 主引用文献 Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control. Elife, 6, 2017
6EFW	Crystal structure of a YjeF family protein from Cryptococcus neoformans var. grubii serotype A 分子名称: ATP-dependent (S)-NAD(P)H-hydrate dehydratase, PHOSPHATE ION, SODIUM ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-08-17 公開日 2018-09-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of a YjeF family protein from Cryptococcus neoformans var. grubii serotype A TO BE PUBLISHED
7N57	Crystal structure of R20A human Galectin-7 mutant in presence of lactose 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Galectin-7, ... 著者 Pham, N.T.H, Calmettes, C, Doucet, N. 登録日 2021-06-04 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Crystal structure of R20A human Galectin-7 mutant To Be Published
6EN4	SF3b core in complex with a splicing modulator 分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ... 著者 Cretu, C, Pena, V. 登録日 2017-10-04 公開日 2018-06-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds. Mol. Cell, 70, 2018
7MXR	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (r-2) 分子名称: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... 著者 Shi, Y, Beese, L.S. 登録日 2021-05-19 公開日 2023-05-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.101 Å) 主引用文献 Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
7MXS	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (cr) 分子名称: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... 著者 Shi, Y, Beese, L.S. 登録日 2021-05-19 公開日 2023-05-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.798 Å) 主引用文献 Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
7MXV	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (ur) 分子名称: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... 著者 Shi, Y, Beese, L.S. 登録日 2021-05-19 公開日 2023-05-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.211 Å) 主引用文献 Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
7MXQ	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (r-1) 分子名称: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... 著者 Shi, Y, Beese, L.S. 登録日 2021-05-19 公開日 2023-05-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.23 Å) 主引用文献 Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
7MXW	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' flap DNA (uf1) 分子名称: CALCIUM ION, DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*AP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), ... 著者 Shi, Y, Beese, L.S. 登録日 2021-05-19 公開日 2023-05-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.836 Å) 主引用文献 Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
6EKS	Vibrio cholerae neuraminidase complexed with oseltamivir carboxylate 分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, GLYCEROL, ... 著者 Schuetz, A, Heinemann, U. 登録日 2017-09-27 公開日 2017-11-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Different Inhibitory Potencies of Oseltamivir Carboxylate, Zanamivir, and Several Tannins on Bacterial and Viral Neuraminidases as Assessed in a Cell-Free Fluorescence-Based Enzyme Inhibition Assay. Molecules, 22, 2017
8SO5	Crystal structure of the engineered quorum quenching acylase MacQ variant M1 - acylated form 分子名称: DECANOIC ACID, Protein related to penicillin acylase 著者 Sompiyachoke, K, Elias, M. 登録日 2023-04-28 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Engineering quorum quenching acylases with improved kinetic and biochemical properties. Protein Sci., 33, 2024
6ELA	Crystal structure of MMP12 in complex with inhibitor BE4. 分子名称: (2~{S})-2-[2-[4-(4-methoxyphenyl)phenyl]sulfanylphenyl]pentanedioic acid, 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, ... 著者 Ciccone, L, Tepshi, L, Nuti, E, Rossello, A, Stura, E.A. 登録日 2017-09-28 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.485 Å) 主引用文献 Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies. J. Med. Chem., 61, 2018
8SEH	PHF Tau from Down Syndrome 分子名称: Microtubule-associated protein tau 著者 Hoq, M.R, Bharath, S.R, Jiang, W, Vago, F.S. 登録日 2023-04-10 公開日 2024-04-03 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Cryo-EM structures of amyloid-beta and tau filaments in Down syndrome. Nat.Struct.Mol.Biol., 31, 2024
4MEC	Crystal structure of RAT Heme oxygenase-1 in complex with ZN(II)-Protoporphyrin IX 分子名称: Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING ZN 著者 Sugishima, M. 登録日 2013-08-26 公開日 2014-08-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Distal regulation of heme binding of heme oxygenase-1 mediated by conformational fluctuations Biochemistry, 54, 2015
6EMH	Crystal structure of JNK3 in complex with a pyridinylimidazole inhibitor 分子名称: 1,2-ETHANEDIOL, 4-(4-methyl-1~{H}-imidazol-5-yl)-~{N}-(4-morpholin-4-ylphenyl)pyridin-2-amine, BETA-MERCAPTOETHANOL, ... 著者 Macedo, J.T, Stehle, T, Blaum, B.S. 登録日 2017-10-02 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Structural Optimization of a Pyridinylimidazole Scaffold: Shifting the Selectivity from p38 alpha Mitogen-Activated Protein Kinase to c-Jun N-Terminal Kinase 3. ACS Omega, 3, 2018
6EO4	Physcomitrella patens BBE-like 1 wild-type 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, PpBBE-like 1 著者 Toplak, M, Winkler, A, Macheroux, P. 登録日 2017-10-09 公開日 2018-04-18 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The single berberine bridge enzyme homolog of Physcomitrella patens is a cellobiose oxidase. FEBS J., 285, 2018
8F2Z	LSD1-CoREST in complex with AW2, short soaking 分子名称: Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-[(1R,3S,3aS,13R)-3-([1,1'-biphenyl]-4-yl)-1-hydroxy-10,11-dimethyl-4,6-dioxo-2,3,5,6-tetrahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) 著者 Caroli, J, Mattevi, A. 登録日 2022-11-09 公開日 2024-06-12 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 to be published
4MGQ	PbXyn10C CBM APO 分子名称: CALCIUM ION, Glycosyl hydrolase family 10 著者 Chekan, J.R, Nair, S.K. 登録日 2013-08-28 公開日 2014-08-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Xylan utilization in human gut commensal bacteria is orchestrated by unique modular organization of polysaccharide-degrading enzymes. Proc.Natl.Acad.Sci.USA, 111, 2014
6EOQ	DPP9 - Apo 分子名称: Dipeptidyl peptidase 9 著者 Ross, B.R, Huber, R. 登録日 2017-10-10 公開日 2018-02-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8SD8	Carbonic anhydrase II radiation damage RT 91-120 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Combs, J.E, Mckenna, R. 登録日 2023-04-06 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.789 Å) 主引用文献 XFEL structure of carbonic anhydrase II: a comparative study of XFEL, NMR, X-ray and neutron structures. Acta Crystallogr D Struct Biol, 80, 2024

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