7N33
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n33 by Molmil](/molmil-images/mine/7n33) | SARS-CoV-2 Nsp15 endoribonuclease pre-cleavage state | 分子名称: | RNA (5'-R(*A)-D(*(UFT))-R(P*A)-3'), Uridylate-specific endoribonuclease | 著者 | Frazier, M.N, Dillard, L.B, Krahn, J.M, Stanley, R.E. | 登録日 | 2021-05-31 | 公開日 | 2021-06-09 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U. Nucleic Acids Res., 49, 2021
|
|
6DOW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dow by Molmil](/molmil-images/mine/6dow) | |
6DP9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dp9 by Molmil](/molmil-images/mine/6dp9) | |
6DPM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dpm by Molmil](/molmil-images/mine/6dpm) | |
8F49
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8f49 by Molmil](/molmil-images/mine/8f49) | |
6DLK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dlk by Molmil](/molmil-images/mine/6dlk) | |
4KR8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kr8 by Molmil](/molmil-images/mine/4kr8) | |
8QOU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8qou by Molmil](/molmil-images/mine/8qou) | Reactive intermediate deaminase A mutant - R107K | 分子名称: | 1,2-ETHANEDIOL, 2-iminobutanoate/2-iminopropanoate deaminase, DI(HYDROXYETHYL)ETHER, ... | 著者 | Rizzi, G, Visentin, C, Di Pisa, F, Ricagno, S. | 登録日 | 2023-09-29 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Reactive intermediate deaminase A mutant - R107K To Be Published
|
|
7N1L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n1l by Molmil](/molmil-images/mine/7n1l) | |
8EMQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8emq by Molmil](/molmil-images/mine/8emq) | Mouse apoferritin heavy chain with zinc determined using single-particle cryo-EM with Apollo camera. | 分子名称: | FE (III) ION, Ferritin heavy chain, N-terminally processed, ... | 著者 | Peng, R, Fu, X, Mendez, J.H, Randolph, P.H, Bammes, B, Stagg, S.M. | 登録日 | 2022-09-28 | 公開日 | 2022-12-21 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (1.66 Å) | 主引用文献 | Characterizing the resolution and throughput of the Apollo direct electron detector. J Struct Biol X, 7, 2023
|
|
6DFK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dfk by Molmil](/molmil-images/mine/6dfk) | Crystal structure of the 11S subunit of the Plasmodium falciparum proteasome, PA28 | 分子名称: | SULFATE ION, Subunit of proteaseome activator complex,putative | 著者 | Xie, S.C, Metcalfe, R.D, Gillett, D.L, Tilley, L, Griffin, M.D.W. | 登録日 | 2018-05-15 | 公開日 | 2019-08-07 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis. Nat Microbiol, 4, 2019
|
|
6DP6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dp6 by Molmil](/molmil-images/mine/6dp6) | |
6DPH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dph by Molmil](/molmil-images/mine/6dph) | |
4KPV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kpv by Molmil](/molmil-images/mine/4kpv) | Crystal structure of the complex of ribosome inactivating protein from Momordica balsamina with Pyrimidine-2,4(1H,3H)-dione at 2.57 A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, URACIL, rRNA N-glycosidase | 著者 | Yamini, S, Pandey, S, Kushwaha, G.S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2013-05-14 | 公開日 | 2013-05-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Crystal structure of the complex of ribosome inactivating protein from Momordica balsamina with Pyrimidine-2,4(1H,3H)-dione at 2.57 A resolution To be Published
|
|
6DQ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dq9 by Molmil](/molmil-images/mine/6dq9) | Linked KDM5A JMJ Domain Bound to the Covalent Inhibitor N69 i.e. [2-((3-acrylamidophenyl)(2-(piperidin-1-yl)ethoxy)methyl)thieno[3,2-b]pyridine-7-carboxylic acid] | 分子名称: | 1,2-ETHANEDIOL, 2-{(R)-[3-(acryloylamino)phenyl][2-(piperidin-1-yl)ethoxy]methyl}thieno[3,2-b]pyridine-7-carboxylic acid, DIMETHYL SULFOXIDE, ... | 著者 | Horton, J.R, Cheng, X. | 登録日 | 2018-06-10 | 公開日 | 2018-11-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.748 Å) | 主引用文献 | Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A. J. Med. Chem., 61, 2018
|
|
7N7B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n7b by Molmil](/molmil-images/mine/7n7b) | crystal structure of the N-formyltrasferase HCAN_0200 from Helicobacter canadensis on complex with folinic acid and dTDP-3-aminofucose | 分子名称: | (3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl][hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Heisdorf, C.J, Thoden, J.B, Holden, H.M. | 登録日 | 2021-06-10 | 公開日 | 2021-06-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Investigation of the enzymes required for the biosynthesis of an unusual formylated sugar in the emerging human pathogen Helicobacter canadensis. Protein Sci., 30, 2021
|
|
6DQN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dqn by Molmil](/molmil-images/mine/6dqn) | Class 1 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | 著者 | Hite, R.K, Paknejad, N. | 登録日 | 2018-06-11 | 公開日 | 2018-08-01 | 最終更新日 | 2019-11-20 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
|
|
8F41
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8f41 by Molmil](/molmil-images/mine/8f41) | 3-methylcrotonyl-CoA carboxylase in filament, alpha-subunit centered | 分子名称: | 3-methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit, ... | 著者 | Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H. | 登録日 | 2022-11-10 | 公開日 | 2023-01-11 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase. Structure, 31, 2023
|
|
8EN7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8en7 by Molmil](/molmil-images/mine/8en7) | Mouse apoferritin heavy chain without zinc determined using single-particle cryo-EM with Apollo camera. | 分子名称: | FE (III) ION, Ferritin heavy chain, N-terminally processed | 著者 | Peng, R, Fu, X, Mendez, J.H, Randolph, P.H, Bammes, B, Stagg, S.M. | 登録日 | 2022-09-28 | 公開日 | 2022-12-21 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (1.68 Å) | 主引用文献 | Characterizing the resolution and throughput of the Apollo direct electron detector. J Struct Biol X, 7, 2023
|
|
8F1G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8f1g by Molmil](/molmil-images/mine/8f1g) | Crystal structure of human WDR5 in complex with compound WM662 | 分子名称: | (2S)-2-({(2S)-3-(3'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-1-[(1H-tetrazol-5-yl)amino]propan-2-yl}oxy)propanoic acid, GLYCEROL, SULFATE ION, ... | 著者 | Liu, H. | 登録日 | 2022-11-05 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction. Acs Chem.Biol., 18, 2023
|
|
7NKU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nku by Molmil](/molmil-images/mine/7nku) | diazaborine bound Drg1(AFG2) | 分子名称: | 6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL, ATPase family gene 2 protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Prattes, M, Bergler, H, Haselbach, D. | 登録日 | 2021-02-19 | 公開日 | 2021-06-23 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine. Nat Commun, 12, 2021
|
|
6DK7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dk7 by Molmil](/molmil-images/mine/6dk7) | RetS histidine kinase region with cobalt | 分子名称: | COBALT (II) ION, RetS (Regulator of Exopolysaccharide and Type III Secretion) | 著者 | Mancl, J.M, Schubot, F.D. | 登録日 | 2018-05-29 | 公開日 | 2019-03-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Helix Cracking Regulates the Critical Interaction between RetS and GacS in Pseudomonas aeruginosa. Structure, 27, 2019
|
|
8F3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8f3d by Molmil](/molmil-images/mine/8f3d) | 3-methylcrotonyl-CoA carboxylase in filament, beta-subunit centered | 分子名称: | 3-methylcrotonyl-CoA carboxylase alpha-subunit, 3-methylcrotonyl-CoA carboxylase beta-subunit, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL | 著者 | Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H. | 登録日 | 2022-11-09 | 公開日 | 2023-01-11 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase. Structure, 31, 2023
|
|
8QRQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8qrq by Molmil](/molmil-images/mine/8qrq) | ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.2) | 分子名称: | GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION | 著者 | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | 登録日 | 2023-10-09 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | 主引用文献 | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
|
|
7N7A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n7a by Molmil](/molmil-images/mine/7n7a) | crystal structure of the dTDP-Qui3N N-formyltransferase from Helicobacter canadensis, apo form | 分子名称: | 1,2-ETHANEDIOL, Formyl_trans_N domain-containing protein | 著者 | Heisdorf, C.J, Thoden, J.B, Holden, H.M. | 登録日 | 2021-06-10 | 公開日 | 2021-06-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Investigation of the enzymes required for the biosynthesis of an unusual formylated sugar in the emerging human pathogen Helicobacter canadensis. Protein Sci., 30, 2021
|
|