PDB: 46188 件ウェブページステータス検索Chemie searchBIRD

---

5FPE	Structure of heat shock-related 70kDA protein 2 with small-molecule ligand 1H-1,2,4-triazol-3-amine (AT485) in an alternate binding site. 分子名称: 3-AMINO-1,2,4-TRIAZOLE, HEAT SHOCK-RELATED 70KDA PROTEIN 2 著者 Jhoti, H, Ludlow, R.F, Patel, S, Saini, H.K, Tickle, I.J, Verdonk, M. 登録日 2015-11-28 公開日 2015-12-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Detection of Secondary Binding Sites in Proteins Using Fragment Screening. Proc.Natl.Acad.Sci.USA, 112, 2015
6I9L	JmjC domain-containing protein 5 (JMJD5) in complex with Mn and pyridine-2,4-dicarboxylic acid (2,4-PDCA) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, JmjC domain-containing protein 5, MANGANESE (II) ION, ... 著者 Chowdhury, R, Islam, M.S, Schofield, C.J. 登録日 2018-11-23 公開日 2019-12-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Structural analysis of the 2-oxoglutarate binding site of the circadian rhythm linked oxygenase JMJD5. Sci Rep, 12, 2022
7M3P	Xrcc4-Spc110p(164-207) fusion 分子名称: Xrcc4-Spc110p(164-207) 著者 Brilot, A.F, Lyon, A.S, Zelter, A, Viswanath, S, Maxwell, A, MacCoss, M.J, Muller, E.G, Sali, A, Davis, T.N, Agard, D.A. 登録日 2021-03-18 公開日 2021-05-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.0000186 Å) 主引用文献 CM1-driven assembly and activation of yeast gamma-tubulin small complex underlies microtubule nucleation. Elife, 10, 2021
3WOA	Crystal structure of lambda repressor (1-45) fused with maltose-binding protein 分子名称: Repressor protein CI, Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Hanazono, Y, Takeda, K, Miki, K. 登録日 2013-12-25 公開日 2015-04-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Co-translational folding of alpha-helical proteins: structural studies of intermediate-length variants of the lambda repressor. FEBS Open Bio, 8, 2018
5H2X	Crystal structure of the karyopherin Kap60p bound to the SUMO protease Ulp1p (150-172) 分子名称: Importin subunit alpha, Ubiquitin-like-specific protease 1 著者 Hirano, H, Matsuura, Y. 登録日 2016-10-18 公開日 2016-12-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of the Karyopherins Kap121p and Kap60p Bound to the Nuclear Pore-Targeting Domain of the SUMO Protease Ulp1p J. Mol. Biol., 429, 2017
8TEW	Human cytomegalovirus penton vertex, CVSC-bound configuration 分子名称: Capsid vertex component 1, Capsid vertex component 2, Large structural phosphoprotein, ... 著者 Jih, J, Liu, Y.T, Liu, W, Zhou, H. 登録日 2023-07-07 公開日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.02 Å) 主引用文献 The incredible bulk: Human cytomegalovirus tegument architectures uncovered by AI-empowered cryo-EM. Sci Adv, 10, 2024
2HBM	Structure of the yeast nuclear exosome component, Rrp6p, reveals an interplay between the active site and the HRDC domain; Protein in complex with Mn, Zn, and UMP 分子名称: Exosome complex exonuclease RRP6, MANGANESE (II) ION, URIDINE-5'-MONOPHOSPHATE, ... 著者 Midtgaard, S.F, Assenholt, J, Jonstrup, A.T, Van, L.B, Jensen, T.H, Brodersen, D.E. 登録日 2006-06-14 公開日 2006-07-25 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of the nuclear exosome component Rrp6p reveals an interplay between the active site and the HRDC domain. Proc.Natl.Acad.Sci.Usa, 103, 2006
5FPM	Structure of heat shock-related 70kDA protein 2 with small-molecule ligand 5-phenyl-1,3,4-oxadiazole-2-thiol (AT809) in an alternate binding site. 分子名称: 5-PHENYL-1,3,4-OXADIAZOLE-2-THIOL, HEAT SHOCK-RELATED 70KDA PROTEIN 2 著者 Jhoti, H, Ludlow, R.F, Patel, S, Saini, H.K, Tickle, I.J, Verdonk, M. 登録日 2015-12-02 公開日 2015-12-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Detection of Secondary Binding Sites in Proteins Using Fragment Screening. Proc.Natl.Acad.Sci.USA, 112, 2015
2KUU	Solution Structure of K10 TLS RNA (GC mutant in upper helix) 分子名称: K10 TLS RNA 著者 Bullock, S.L, Ringel, I, Ish-Horowicz, D, Lukavsky, P.J. 登録日 2010-03-01 公開日 2010-05-19 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A'-form RNA helices are required for cytoplasmic mRNA transport in Drosophila. Nat.Struct.Mol.Biol., 17, 2010
8E2R	Crystal structure of TadAC-1.14 分子名称: GLYCEROL, ZINC ION, tRNA-specific adenosine deaminase 1.14 著者 Feliciano, P.R, Lee, S.J, Ciaramella, G. 登録日 2022-08-15 公開日 2023-01-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Improved cytosine base editors generated from TadA variants. Nat.Biotechnol., 41, 2023
8E2S	Crystal structure of TadAC-1.19 分子名称: ZINC ION, tRNA-specific adenosine deaminase 1.19 著者 Feliciano, P.R, Lee, S.J, Ciaramella, G. 登録日 2022-08-15 公開日 2023-01-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Improved cytosine base editors generated from TadA variants. Nat.Biotechnol., 41, 2023
2KW4	Solution NMR Structure of the Holo Form of a Ribonuclease H domain from D.hafniense, Northeast Structural Genomics Consortium Target DhR1A 分子名称: MAGNESIUM ION, Uncharacterized protein 著者 Mills, J.L, Eletsky, A, Hua, J, Belote, R.L, Buchwald, W.A, Ciccosanti, C, Janjua, H, Nair, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) 登録日 2010-03-31 公開日 2010-05-05 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Northeast Structural Genomics Consortium Target DhR1A To be Published
2KQ2	Solution NMR structure of the apo form of a ribonuclease H domain of protein DSY1790 from Desulfitobacterium hafniense, Northeast Structural Genomics target DhR1A 分子名称: Ribonuclease H-related protein 著者 Mills, J.L, Eletsky, A, Hua, J, Belote, R.L, Buchwald, W.A, Ciccosanti, C, Janjua, H, Nair, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) 登録日 2009-10-24 公開日 2010-03-16 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution NMR structure of the apo form of a ribonuclease H domain of protein DSY1790 from Desulfitobacterium hafniense, Northeast Structural Genomics target DhR1A To be Published
8TIA	CryoEM structure of locally-refined tetramer of Shedu nuclease domain from Bacillus cereus 分子名称: Shedu protein SduA 著者 Gu, Y, Corbett, K. 登録日 2023-07-19 公開日 2024-07-31 実験手法 ELECTRON MICROSCOPY (2.77 Å) 主引用文献 Shedu anti-phage nucleases share a common enzymatic core regulated by diverse sensor domains to be published
8TI9	CryoEM structure of octamer assembly of Shedu nuclease domain from Bacillus cereus 分子名称: Shedu protein SduA 著者 Gu, Y, Corbett, K. 登録日 2023-07-19 公開日 2024-07-31 実験手法 ELECTRON MICROSCOPY (3.19 Å) 主引用文献 Shedu anti-phage nucleases share a common enzymatic core regulated by diverse sensor domains to be published
8TI8	CryoEM structure of Shedu from Bacillus cereus 分子名称: Shedu protein SduA 著者 Gu, Y, Corbett, K. 登録日 2023-07-19 公開日 2024-07-31 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Shedu anti-phage nucleases share a common enzymatic core regulated by diverse sensor domains to be published
6H0U	Glycogen synthase kinase-3 beta (GSK3) complex with a covalent [1,2,4]triazolo[1,5-a][1,3,5]triazine inhibitor 分子名称: (2~{R})-3-[7-azanyl-5-(cyclohexylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-2-yl]-2-cyano-propanamide, CHLORIDE ION, GLYCEROL, ... 著者 Marcovich, I, Demitri, N, De Zorzi, R, Storici, P. 登録日 2018-07-10 公開日 2019-05-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A Triazolotriazine-Based Dual GSK-3 beta /CK-1 delta Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition. Chemmedchem, 14, 2019
5ETB	Crystal structure of the human BRPF1 bromodomain in complex with SEED13 分子名称: 1-(7-methyl-1~{H}-indol-3-yl)ethanone, NITRATE ION, Peregrin 著者 Zhu, J, Caflisch, A. 登録日 2015-11-17 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions. J.Med.Chem., 59, 2016
5ETD	Crystal structure of the human BRPF1 bromodomain in complex with SEED14 分子名称: 1-(1~{H}-indol-3-yl)ethanone, NITRATE ION, Peregrin 著者 Zhu, J, Caflisch, A. 登録日 2015-11-17 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions. J.Med.Chem., 59, 2016
2J4K	Crystal structure of uridylate kinase from Sulfolobus solfataricus in complex with UMP to 2.2 Angstrom resolution 分子名称: CADMIUM ION, MAGNESIUM ION, URIDINE-5'-MONOPHOSPHATE, ... 著者 Jensen, K.S, Johansson, E, Jensen, K.F. 登録日 2006-09-01 公開日 2007-02-27 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and Enzymatic Investigation of the Sulfolobus Solfataricus Uridylate Kinase Shows Competitive Utp Inhibition and the Lack of GTP Stimulation Biochemistry, 46, 2007
8U77	Crystal structure of Taf14 in complex with Yng1 分子名称: Protein YNG1, Transcription initiation factor TFIID subunit 14 著者 Nguyen, M.C, Wei, P.C, Zhang, G.Y, Kutateladze, T.G. 登録日 2023-09-14 公開日 2024-08-21 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Molecular insight into interactions between the Taf14, Yng1 and Sas3 subunits of the NuA3 complex. Nat Commun, 15, 2024
8U3S	Structure of human TIRR in complex with VHH4 nanobody 分子名称: Nanobody, Tudor-interacting repair regulator protein 著者 Botuyan, M.V, Mer, G. 登録日 2023-09-08 公開日 2024-09-04 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity. Nat Commun, 15, 2024
5G4V	Association of four two-k-turn units based on Kt-7 3bG,3nC, forming a square-shaped structure 分子名称: 50S RIBOSOMAL PROTEIN L7AE, HMKT-7 著者 Huang, L, Lilley, D.M.J. 登録日 2016-05-17 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.87 Å) 主引用文献 A Quasi-Cyclic RNA Nano-Scale Molecular Object Constructed Using Kink Turns. Nanoscale, 8, 2016
8C76	Light-state 2.5 Angstrom wild-type X-ray crystal structure of the cobalamin binding domain belonging to a light-dependent transcription regulator TtCarH obtained under aerobic conditions from a form 2 crystal illuminated during 5 s 分子名称: COBALAMIN, Probable transcriptional regulator 著者 Rios-Santacruz, R, Colletier, J.P, Schiro, G, Weik, M. 登録日 2023-01-12 公開日 2023-08-09 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Redox driven B 12 -ligand switch drives CarH photoresponse. Nat Commun, 14, 2023
5GMK	Cryo-EM structure of the Catalytic Step I spliceosome (C complex) at 3.4 angstrom resolution 分子名称: 5'-Exon, 5'-Splicing Site, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Wan, R, Yan, C, Bai, R, Huang, G, Shi, Y. 登録日 2016-07-14 公開日 2016-08-17 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of a yeast catalytic step I spliceosome at 3.4 angstrom resolution Science, 353, 2016

<1400140114021403140414051406140714081409141014111412141314141415>