8E2S

Crystal structure of TadAC-1.19

Summary for 8E2S

• Entry DOI: 10.2210/pdb8e2s/pdb
• Descriptor: tRNA-specific adenosine deaminase 1.19, ZINC ION (3 entities in total)
• Functional Keywords: deaminase, tadac, dna binding protein
• Biological source: Escherichia coli
• Total number of polymer chains: 8
• Total formula weight: 149855.71

Authors

Feliciano, P.R.,Lee, S.J.,Ciaramella, G. (deposition date: 2022-08-15, release date: 2023-01-11, Last modification date: 2023-10-25)

• Primary citation: Lam, D.K.,Feliciano, P.R.,Arif, A.,Bohnuud, T.,Fernandez, T.P.,Gehrke, J.M.,Grayson, P.,Lee, K.D.,Ortega, M.A.,Sawyer, C.,Schwaegerle, N.D.,Peraro, L.,Young, L.,Lee, S.J.,Ciaramella, G.,Gaudelli, N.M.; Improved cytosine base editors generated from TadA variants.; Nat.Biotechnol., 41:686-697, 2023; PubMed: 36624149; DOI: 10.1038/s41587-022-01611-9

Experimental method

X-RAY DIFFRACTION (2.95 Å)