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3HPL
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BU of 3hpl by Molmil
KcsA E71H-F103A mutant in the closed state
分子名称: Antibody Fab heavy chain, Antibody fab light chain, POTASSIUM ION, ...
著者Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E.
登録日2009-06-04
公開日2010-06-23
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for the coupling between activation and inactivation gates in K(+) channels.
Nature, 466, 2010
2KJX
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BU of 2kjx by Molmil
Solution structure of the extracellular domain of JTB
分子名称: Jumping translocation breakpoint protein
著者Rousseau, F, Lingel, A, Pan, B, Fairbrother, W.J, Bazan, F.
登録日2009-06-10
公開日2010-08-11
最終更新日2012-04-18
実験手法SOLUTION NMR
主引用文献The structure of the extracellular domain of the jumping translocation breakpoint protein reveals a variation of the midkine fold.
J.Mol.Biol., 415, 2012
2KLL
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BU of 2kll by Molmil
Solution structure of human interleukin-33
分子名称: Interleukin-33
著者Lingel, A, Fairbrother, W.
登録日2009-07-06
公開日2009-11-17
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors--insight into heterotrimeric IL-1 signaling complexes.
Structure, 17, 2009
3IAI
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BU of 3iai by Molmil
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 9, ...
著者Alterio, V, Di Fiore, A, De Simone, G.
登録日2009-07-14
公開日2009-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX.
Proc.Natl.Acad.Sci.USA, 106, 2009
3IK3
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BU of 3ik3 by Molmil
AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance
分子名称: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, Proto-oncogene tyrosine-protein kinase ABL1
著者Zhou, T.
登録日2009-08-05
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance.
Cancer Cell, 16, 2009
2WQ1
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BU of 2wq1 by Molmil
GCN4 leucine zipper mutant with three IxxNTxx motifs coordinating bromide
分子名称: BROMIDE ION, GENERAL CONTROL PROTEIN GCN4
著者Hartmann, M.D, Hernandez Alvarez, B, Lupas, A.N.
登録日2009-08-12
公開日2009-11-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献A Coiled-Coil Motif that Sequesters Ions to the Hydrophobic Core.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WQ0
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BU of 2wq0 by Molmil
GCN4 leucine zipper mutant with three IxxNTxx motifs coordinating chloride
分子名称: CHLORIDE ION, GENERAL CONTROL PROTEIN GCN4
著者Hartmann, M.D, Hernandez Alvarez, B, Lupas, A.N.
登録日2009-08-12
公開日2009-11-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献A Coiled-Coil Motif that Sequesters Ions to the Hydrophobic Core.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WPZ
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BU of 2wpz by Molmil
GCN4 leucine zipper mutant with two VxxNxxx motifs coordinating chloride
分子名称: CHLORIDE ION, GENERAL CONTROL PROTEIN GCN4
著者Zeth, K, Hartmann, M.D, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B.
登録日2009-08-12
公開日2009-11-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献A Coiled-Coil Motif that Sequesters Ions to the Hydrophobic Core.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WPY
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BU of 2wpy by Molmil
GCN4 leucine zipper mutant with one VxxNxxx motif coordinating chloride
分子名称: CHLORIDE ION, GENERAL CONTROL PROTEIN GCN4
著者Zeth, K, Hartmann, M.D, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B.
登録日2009-08-12
公開日2009-11-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A Coiled-Coil Motif that Sequesters Ions to the Hydrophobic Core.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WQ3
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BU of 2wq3 by Molmil
GCN4 leucine zipper mutant with three IxxNTxx motifs coordinating chloride and nitrate
分子名称: CHLORIDE ION, GENERAL CONTROL PROTEIN GCN4, NITRATE ION
著者Hartmann, M.D, Hernandez Alvarez, B, Lupas, A.N.
登録日2009-08-12
公開日2009-11-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献A Coiled-Coil Motif that Sequesters Ions to the Hydrophobic Core.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WQ2
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BU of 2wq2 by Molmil
GCN4 leucine zipper mutant with three IxxNTxx motifs coordinating iodide
分子名称: GENERAL CONTROL PROTEIN GCN4, IODIDE ION
著者Hartmann, M.D, Hernandez Alvarez, B, Lupas, A.N.
登録日2009-08-12
公開日2009-11-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献A Coiled-Coil Motif that Sequesters Ions to the Hydrophobic Core.
Proc.Natl.Acad.Sci.USA, 106, 2009
3IPM
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BU of 3ipm by Molmil
Crystal Structure of Archaeal 20S Proteasome in Complex with the C-terminus of PAN
分子名称: Proteasome activator PA26, Proteasome-activating nucleotidase fusion protein, Proteasome subunit alpha, ...
著者Yu, Y, Cheng, Y.
登録日2009-08-17
公開日2009-12-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions.
Embo J., 29, 2010
3IVH
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BU of 3ivh by Molmil
Design and Synthesis of Potent BACE-1 Inhibitors with Cellular Activity: Structure-Activity Relationship of P1 Substituents
分子名称: Beta-secretase 1, N-[(1S,2R)-3-{[1-(3-tert-butylphenyl)cyclohexyl]amino}-1-(3,5-difluorobenzyl)-2-hydroxypropyl]acetamide
著者Pan, H.
登録日2009-09-01
公開日2010-01-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design and synthesis of cell potent BACE-1 inhibitors: structure-activity relationship of P1' substituents.
Bioorg.Med.Chem.Lett., 19, 2009
3IVI
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BU of 3ivi by Molmil
Design and Synthesis of Potent BACE-1 Inhibitors with Cellular Activity: Structure-Activity Relationship of P1 Substituents
分子名称: Beta-secretase 1, GLYCEROL, N-[(1S,2R)-3-{[(5S)-5-(3-tert-butylphenyl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]amino}-1-(3,5-difluorobenzyl)-2-hydroxypropyl]acetamide, ...
著者Pan, H.
登録日2009-09-01
公開日2010-01-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Design and synthesis of cell potent BACE-1 inhibitors: structure-activity relationship of P1' substituents.
Bioorg.Med.Chem.Lett., 19, 2009
3JPX
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BU of 3jpx by Molmil
EED: A Novel Histone Trimethyllysine Binder Within The EED-EZH2 Polycomb Complex
分子名称: HISTONE PEPTIDE, Polycomb protein EED
著者Xu, C, Bian, C.B, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2009-09-04
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
3JRM
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BU of 3jrm by Molmil
Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator
分子名称: Proteasome activator protein PA26, Proteasome subunit alpha, Proteasome subunit beta
著者Stadtmueller, B.M, Whitby, F.G, Hill, C.P.
登録日2009-09-08
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural models for interactions between the 20S proteasome and its PAN/19S activators.
J.Biol.Chem., 285, 2010
3JSE
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BU of 3jse by Molmil
Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator
分子名称: Proteasome activator protein PA26, Proteasome subunit alpha, Proteasome subunit beta
著者Stadtmueller, B.M, Whitby, F.G, Hill, C.P.
登録日2009-09-10
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural models for interactions between the 20S proteasome and its PAN/19S activators.
J.Biol.Chem., 285, 2010
3JTL
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BU of 3jtl by Molmil
Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator
分子名称: Proteasome activator protein PA26, Proteasome subunit alpha, Proteasome subunit beta
著者Stadtmueller, B.M, Whitby, F.G, Hill, C.P.
登録日2009-09-12
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Models for Interactions between the 20S proteasome and its PAN/19S activators.
J.Biol.Chem., 285, 2010
3JYN
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BU of 3jyn by Molmil
Crystal structures of Pseudomonas syringae pv. Tomato DC3000 quinone oxidoreductase complexed with NADPH
分子名称: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Quinone oxidoreductase
著者Pan, X, Zhang, H, Gao, Y, Li, M, Chang, W.
登録日2009-09-22
公開日2010-01-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal structures of Pseudomonas syringae pv. tomato DC3000 quinone oxidoreductase and its complex with NADPH
Biochem.Biophys.Res.Commun., 390, 2009
3JYL
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BU of 3jyl by Molmil
Crystal structures of Pseudomonas syringae pv. Tomato DC3000 quinone oxidoreductase
分子名称: Quinone oxidoreductase
著者Pan, X, Zhang, H, Gao, Y, Li, M, Chang, W.
登録日2009-09-22
公開日2010-01-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of Pseudomonas syringae pv. tomato DC3000 quinone oxidoreductase and its complex with NADPH
Biochem.Biophys.Res.Commun., 390, 2009
3JZN
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BU of 3jzn by Molmil
Structure of EED in apo form
分子名称: Polycomb protein EED
著者Xu, C, Bian, C.B, Ouyang, H, Qiu, W, MacKenzie, F, Min, J, Structural Genomics Consortium (SGC)
登録日2009-09-23
公開日2009-12-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
3JZG
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BU of 3jzg by Molmil
Structure of EED in complex with H3K27me3
分子名称: HISTONE PEPTIDE, Polycomb protein EED
著者Xu, C, Bian, C.B, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2009-09-23
公開日2009-12-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
3JZH
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BU of 3jzh by Molmil
EED-H3K79me3
分子名称: HISTONE PEPTIDE, Polycomb protein EED
著者Xu, C, Bian, C.B, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2009-09-23
公開日2009-12-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
3K1R
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BU of 3k1r by Molmil
Structure of harmonin NPDZ1 in complex with the SAM-PBM of Sans
分子名称: Harmonin, Usher syndrome type-1G protein
著者Pan, L, Yan, J, Zhang, M.
登録日2009-09-28
公開日2010-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins
Proc.Natl.Acad.Sci.USA, 107, 2010
3K27
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Complex structure of EED and trimethylated H3K9
分子名称: HISTONE PEPTIDE, Polycomb protein EED
著者Bian, C.B, Xu, C, Qiu, W, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2009-09-29
公開日2009-12-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010

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