PDB: 2705 件ウェブページステータス検索Chemie searchBIRD

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1TOO	Interleukin 1B Mutant F146W 分子名称: Interleukin-1 beta 著者 Adamek, D.H, Guerrero, L, Caspar, D.L. 登録日 2004-06-14 公開日 2004-12-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and energetic consequences of mutations in a solvated hydrophobic cavity. J.Mol.Biol., 346, 2005
1TP0	Triple mutation in interleukin 1 beta cavity:replacement of phenylalanines with tryptophan. 分子名称: Interleukin-1 beta 著者 Adamek, D.H, Guerrero, L, Caspar, D.L. 登録日 2004-06-15 公開日 2005-02-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and energetic consequences of mutations in a solvated hydrophobic cavity. J.Mol.Biol., 346, 2005
4MI6	Crystal structure of Gpb in complex with SUGAR (N-[4-(5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)BUTANOYL]-BETA-D-GLUCOPYRANOSYLAMINE) 分子名称: Glycogen phosphorylase, muscle form, N-[4-(5,6,7,8-tetrahydronaphthalen-2-yl)butanoyl]-beta-D-glucopyranosylamine 著者 Kantsadi, L.A, Chatzileontiadou, S.M.D, Leonidas, D.D. 登録日 2013-08-30 公開日 2014-07-23 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure based inhibitor design targeting glycogen phosphorylase b. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-beta-d-glucopyranosylamines. Bioorg.Med.Chem., 22, 2014
1TWM	Interleukin-1 Beta Mutant F146Y 分子名称: Interleukin-1 beta 著者 Adamek, D.H, Capsar, D.L. 登録日 2004-07-01 公開日 2004-12-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Structural and energetic consequences of mutations in a solvated hydrophobic cavity. J.Mol.Biol., 346, 2005
1V4I	Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima F132A mutant 分子名称: SULFATE ION, octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Chou, C.C, Ko, T.P, Shr, H.L, Liang, P.H, Wang, A.H.-J. 登録日 2003-11-14 公開日 2004-03-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination J.Biol.Chem., 279, 2004
4MHS	Crystal structure of Gpb in complex with SUGAR (N-[(2E)-3-(BIPHENYL-4-YL)PROP-2-ENOYL]-BETA-D-GLUCOPYRANOSYLAMINE 分子名称: DIMETHYL SULFOXIDE, Glycogen phosphorylase, muscle form, ... 著者 Kantsadi, L.A, Chatzileontiadou, S.M.D, Leonidas, D.D. 登録日 2013-08-30 公開日 2014-07-23 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure based inhibitor design targeting glycogen phosphorylase b. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-beta-d-glucopyranosylamines. Bioorg.Med.Chem., 22, 2014
1V4H	Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima F52A mutant 分子名称: SULFATE ION, octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Chou, C.C, Ko, T.P, Shr, H.L, Liang, P.H, Wang, A.H.-J. 登録日 2003-11-14 公開日 2004-03-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination J.Biol.Chem., 279, 2004
1V4K	Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima S77F mutant 分子名称: SULFATE ION, octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Chou, C.C, Ko, T.P, Shr, H.L, Liang, P.H, Wang, A.H.-J. 登録日 2003-11-14 公開日 2004-03-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination J.Biol.Chem., 279, 2004
1V4J	Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima V73Y mutant 分子名称: SULFATE ION, octoprenyl-diphosphate synthase 著者 Guo, R.T, Kuo, C.J, Chou, C.C, Ko, T.P, Shr, H.L, Liang, P.H, Wang, A.H.-J. 登録日 2003-11-14 公開日 2004-03-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination J.Biol.Chem., 279, 2004
6C57	Crystal structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D) in complex with bisphosphonate inhibitor FV0109 分子名称: Geranylgeranyl pyrophosphate synthase, {[(2-{3-[(4-fluorobenzene-1-carbonyl)amino]phenyl}thieno[2,3-d]pyrimidin-4-yl)amino]methylene}bis(phosphonic acid) 著者 Park, J, Bin, X, Vincent, F, Tsantrizos, Y.S, Berghuis, A.M. 登録日 2018-01-15 公開日 2018-09-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Unraveling the Prenylation-Cancer Paradox in Multiple Myeloma with Novel Geranylgeranyl Pyrophosphate Synthase (GGPPS) Inhibitors. J. Med. Chem., 61, 2018
2F9K	Crystal structure of human FPPS in complex with Zoledronate and Zn2+ 分子名称: Farnesyl Diphosphate Synthase, PHOSPHATE ION, ZINC ION, ... 著者 Rondeau, J.-M, Bitsch, F, Bourgier, E, Geiser, M, Hemmig, R, Kroemer, M, Lehmann, S, Ramage, P, Rieffel, S, Strauss, A, Green, J.R, Jahnke, W. 登録日 2005-12-06 公開日 2006-02-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. Chemmedchem, 1, 2006
2FFR	Crystallographic studies on N-azido-beta-D-glucopyranosylamine, an inhibitor of glycogen phosphorylase: comparison with N-acetyl-beta-D-glucopyranosylamine 分子名称: Glycogen phosphorylase, muscle form, N-(azidoacetyl)-beta-D-glucopyranosylamine, ... 著者 Petsalakis, E.I, Chrysina, E.D, Tiraidis, C, Hadjiloi, T, Leonidas, D.D, Oikonomakos, N.G, Aich, U, Varghese, B, Loganathan, D. 登録日 2005-12-20 公開日 2006-06-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Crystallographic studies on N-azidoacetyl-beta-d-glucopyranosylamine, an inhibitor of glycogen phosphorylase: Comparison with N-acetyl-beta-d-glucopyranosylamine. Bioorg.Med.Chem., 14, 2006
6C56	Crystal structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D) in its Apo form 分子名称: Geranylgeranyl pyrophosphate synthase, {[(2-phenylthieno[2,3-d]pyrimidin-4-yl)amino]methylene}bis(phosphonic acid) 著者 Park, J, Ta, V, Tsantrizos, Y.S, Berghuis, A.M. 登録日 2018-01-15 公開日 2018-09-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Unraveling the Prenylation-Cancer Paradox in Multiple Myeloma with Novel Geranylgeranyl Pyrophosphate Synthase (GGPPS) Inhibitors. J. Med. Chem., 61, 2018
1HIB	THE STRUCTURE OF AN INTERLEUKIN-1 BETA MUTANT WITH REDUCED BIOACTIVITY SHOWS MULTIPLE SUBTLE CHANGES IN CONFORMATION THAT AFFECT PROTEIN-PROTEIN RECOGNITION 分子名称: INTERLEUKIN-1 BETA 著者 Camacho, N.P, Smith, D.R, Goldman, A, Schneider, B, Green, D, Young, P.R, Berman, H.M. 登録日 1993-03-29 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of an interleukin-1 beta mutant with reduced bioactivity shows multiple subtle changes in conformation that affect protein-protein recognition. Biochemistry, 32, 1993
3NP9	Glycogen phosphorylase complexed with 3-(beta-D-glucopyranosyl)-2-hydroxy-5-methoxy-chlorobenzene 分子名称: (1S)-1,5-anhydro-1-(3-chloro-2-hydroxy-5-methoxyphenyl)-D-glucitol, Glycogen phosphorylase, muscle form 著者 Alexacou, K.-M. 登録日 2010-06-28 公開日 2011-06-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Halogen-substituted (C-beta-D-glucopyranosyl)-hydroquinone regioisomers: synthesis, enzymatic evaluation and their binding to glycogen phosphorylase. Bioorg.Med.Chem., 19, 2011
2AZK	Crystal structure for the mutant W136E of Sulfolobus solfataricus hexaprenyl pyrophosphate synthase 分子名称: Geranylgeranyl pyrophosphate synthetase 著者 Sun, H.Y, Ko, T.P, Kuo, C.J, Guo, R.T, Chou, C.C, Liang, P.H, Wang, A.H.J. 登録日 2005-09-12 公開日 2006-03-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures J.Bacteriol., 187, 2005
2AZD	X-Ray studies on Maltodextrin Phosphorylase (MalP) Complexes: recognition of substrates and CATALYTIC mechanism of phosphorylase family 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Maltodextrin phosphorylase, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Geremia, S, Campagnolo, M. 登録日 2005-09-10 公開日 2005-09-20 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 X-ray studies on ternary complexes of maltodextrin phosphorylase. Arch.Biochem.Biophys., 471, 2008
2CXR	Crystal structure of mouse AMF / 6PG complex 分子名称: 6-PHOSPHOGLUCONIC ACID, GLYCEROL, Glucose-6-phosphate isomerase 著者 Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T. 登録日 2005-06-30 公開日 2006-05-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors J.Mol.Biol., 356, 2006
1I1B	CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-1BETA AT 2.0 ANGSTROMS RESOLUTION 分子名称: INTERLEUKIN-1 BETA 著者 Finzel, B.C, Watenpaugh, K.D, Einspahr, H.M. 登録日 1989-12-05 公開日 1990-01-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of recombinant human interleukin-1 beta at 2.0 A resolution. J.Mol.Biol., 209, 1989
2CXT	Crystal structure of mouse AMF / F6P complex 分子名称: 6-O-phosphono-beta-D-fructofuranose, GLYCEROL, Glucose-6-phosphate isomerase 著者 Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T. 登録日 2005-06-30 公開日 2006-05-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors J.Mol.Biol., 356, 2006
2CQL	Solution structure of the N-terminal domain of human ribosomal protein L9 分子名称: 60S ribosomal protein L9 著者 Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-05-20 公開日 2005-11-20 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the N-terminal domain of human ribosomal protein L9 To be Published
2CXO	Crystal structure of mouse AMF / E4P complex 分子名称: D-4-PHOSPHOERYTHRONIC ACID, GLYCEROL, Glucose-6-phosphate isomerase 著者 Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T. 登録日 2005-06-30 公開日 2006-05-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors J.Mol.Biol., 356, 2006
2CXU	Crystal structure of mouse AMF / M6P complex 分子名称: GLYCEROL, Glucose-6-phosphate isomerase, PHOSPHATE ION 著者 Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T. 登録日 2005-06-30 公開日 2006-05-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors J.Mol.Biol., 356, 2006
2CXN	Crystal structure of mouse AMF / phosphate complex 分子名称: GLYCEROL, Glucose-6-phosphate isomerase, PHOSPHATE ION 著者 Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T. 登録日 2005-06-30 公開日 2006-05-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors J.Mol.Biol., 356, 2006
2CVP	Crystal structure of mouse AMF 分子名称: ACETATE ION, GLYCEROL, Glucose-6-phosphate isomerase 著者 Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T. 登録日 2005-06-10 公開日 2006-05-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors J.Mol.Biol., 356, 2006

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