2FFR

Crystallographic studies on N-azido-beta-D-glucopyranosylamine, an inhibitor of glycogen phosphorylase: comparison with N-acetyl-beta-D-glucopyranosylamine

Summary for 2FFR

• Entry DOI: 10.2210/pdb2ffr/pdb
• Related: 1WW2
• Descriptor: Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, N-(azidoacetyl)-beta-D-glucopyranosylamine, ... (4 entities in total)
• Functional Keywords: glycogenolysis, inhibition, type 2 diabetes, transferase
• Biological source: Oryctolagus cuniculus (rabbit)
• Total number of polymer chains: 1
• Total formula weight: 95790.28

Authors

Petsalakis, E.I.,Chrysina, E.D.,Tiraidis, C.,Hadjiloi, T.,Leonidas, D.D.,Oikonomakos, N.G.,Aich, U.,Varghese, B.,Loganathan, D. (deposition date: 2005-12-20, release date: 2006-06-20, Last modification date: 2023-08-30)

• Primary citation: Petsalakis, E.I.,Chrysina, E.D.,Tiraidis, C.,Hadjiloi, T.,Leonidas, D.D.,Oikonomakos, N.G.,Aich, U.,Varghese, B.,Loganathan, D.; Crystallographic studies on N-azidoacetyl-beta-d-glucopyranosylamine, an inhibitor of glycogen phosphorylase: Comparison with N-acetyl-beta-d-glucopyranosylamine.; Bioorg.Med.Chem., 14:5316-5324, 2006; PubMed: 16616506; DOI: 10.1016/j.bmc.2006.03.044

Experimental method

X-RAY DIFFRACTION (2.03 Å)