PDB: 446 件ウェブページステータス検索Chemie searchBIRD

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8G8Z	Cryo-EM structure of 3DVA component 1 of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase plus preQ1 ligand 分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, DNA (31-MER), DNA (39-MER), ... 著者 Porta, J.C, Ohi, M.D, Walter, N.G, Frank, A.T, Deb, I, Meze, K. 登録日 2023-02-20 公開日 2023-06-21 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand. Nat.Struct.Mol.Biol., 30, 2023
8G7E	Cryo-EM structure of 3DVA component 0 of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase plus preQ1 ligand 分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, DNA (31-MER), DNA (39-mer), ... 著者 Porta, J.C, Chauvier, A, Deb, I, Ellinger, E, Frank, A.T, Meze, K, Ohi, M.D, Walter, N.G. 登録日 2023-02-16 公開日 2023-06-21 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand. Nat.Struct.Mol.Biol., 30, 2023
4B5R	SAM-I riboswitch bearing the H. marismortui K-t-7 分子名称: BARIUM ION, POTASSIUM ION, S-ADENOSYLMETHIONINE, ... 著者 Daldrop, P, Lilley, D.M.J. 登録日 2012-08-07 公開日 2013-01-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 The Plasticity of a Structural Motif in RNA: Structural Polymorphism of a Kink Turn as a Function of its Environment. RNA, 19, 2013
2QBZ	Structure of the M-Box Riboswitch Aptamer Domain 分子名称: M-Box RNA, ykoK riboswitch aptamer, MAGNESIUM ION, ... 著者 Dann III, C.E, Winkler, W.C. 登録日 2007-06-18 公開日 2007-09-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure and mechanism of a metal-sensing regulatory RNA Cell(Cambridge,Mass.), 130, 2007
4MGN	Co-crystal structure of the G. kaustophilus glyQS T box riboswitch Stem I in complex with tRNA 分子名称: MAGNESIUM ION, glyQS T box riboswitch, tRNA-glycine 著者 Grigg, J.C, Ke, A. 登録日 2013-08-28 公開日 2013-10-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Determinants for Geometry and Information Decoding of tRNA by T Box Leader RNA. Structure, 21, 2013
6CK4	G96A mutant of the PRPP riboswitch from T. mathranii bound to ppGpp 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5',3'-TETRAPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Reiss, C.W, Knappenberger, A.J, Strobel, S.A. 登録日 2018-02-27 公開日 2018-06-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.097 Å) 主引用文献 Structures of two aptamers with differing ligand specificity reveal ruggedness in the functional landscape of RNA. Elife, 7, 2018
6CK5	PRPP riboswitch from T. mathranii bound to PRPP 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, BARIUM ION, MAGNESIUM ION, ... 著者 Knappenberger, A.J, Reiss, C.W, Strobel, S.A. 登録日 2018-02-27 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structures of two aptamers with differing ligand specificity reveal ruggedness in the functional landscape of RNA. Elife, 7, 2018
5FJC	SAM-I riboswitch bearing the H. marismortui Kt-7 variant C-2bU 分子名称: BARIUM ION, MAGNESIUM ION, POTASSIUM ION, ... 著者 Huang, L, Lilley, D.M.J. 登録日 2015-10-07 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 A Critical Base Pair in K-Turns Determines the Conformational Class Adopted, and Correlates with Biological Function. Nucleic Acids Res., 44, 2016
2KXM	Solution NMR Structure of the 27 nucleotide engineered neomycin sensing riboswitch RNA-ribostmycin complex 分子名称: RIBOSTAMYCIN, RNA (27-MER) 著者 Duchardt-Ferner, E, Weigand, J.E, Ohlenschlager, O, Schmidtke, S.R, Suess, B, Wohnert, J. 登録日 2010-05-10 公開日 2011-04-20 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Highly modular structure and ligand binding by conformational capture in a minimalistic riboswitch. Angew.Chem.Int.Ed.Engl., 49, 2010
6VWV	Transitional unit cell 2 of adenine riboswitch aptamer crystal phase transition upon ligand binding 分子名称: ADENINE, MAGNESIUM ION, POTASSIUM ION, ... 著者 Stagno, J.R, Wang, Y.-X. 登録日 2020-02-20 公開日 2020-11-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Synchronous RNA conformational changes trigger ordered phase transitions in crystals. Nat Commun, 12, 2021
6VWT	Transitional unit cell 1 of adenine riboswitch aptamer crystal phase transition upon ligand binding 分子名称: ADENINE, MAGNESIUM ION, adenine riboswitch aptamer variant 著者 Stagno, J.R, Wang, Y.-X. 登録日 2020-02-20 公開日 2020-11-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.03 Å) 主引用文献 Synchronous RNA conformational changes trigger ordered phase transitions in crystals. Nat Commun, 12, 2021
2LI4	Solution structure of a shortened antiterminator hairpin from a Mg2+ riboswitch 分子名称: RNA (32-MER) 著者 Korth, M.M.T, Sigel, R.K.O. 登録日 2011-08-22 公開日 2012-08-22 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of a shortened antiterminator hairpin from a Mg2+ riboswitch To be Published
6E1V	Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 3: 2-[(9H-carbazol-3-yl)oxy]-N,N-dimethylethan-1-amine 分子名称: 2-[(9H-carbazol-3-yl)oxy]-N,N-dimethylethan-1-amine, RNA (33-MER) 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
6E1S	Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 1: 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine 分子名称: 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine, RNA (33-MER) 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
6E1T	Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 1: 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine, MAGNESIUM ION, ... 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
6E1W	Crystal structure of a class I PreQ1 riboswitch complexed with PreQ1 分子名称: 2-amino-5-(aminomethyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, ACETATE ION, MAGNESIUM ION, ... 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
6E1U	Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 2: 2-[(dibenzo[b,d]furan-2-yl)oxy]-N,N-dimethylethan-1-amine 分子名称: 2-[(dibenzo[b,d]furan-2-yl)oxy]-N,N-dimethylethan-1-amine, MAGNESIUM ION, RNA (33-MER) 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
1Y27	G-riboswitch-guanine complex 分子名称: Bacillus subtilis xpt, GUANINE 著者 Serganov, A, Yuan, Y.R, Patel, D.J. 登録日 2004-11-20 公開日 2004-12-28 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Basis for Discriminative Regulation of Gene Expression by Adenine- and Guanine-Sensing mRNAs Chem.Biol., 11, 2004
3UD4	The C92U mutant c-di-GMP-I riboswitch bound to GpA 分子名称: MAGNESIUM ION, RNA (5'-R(*GP*A)-3'), RNA (92-MER), ... 著者 Smith, K.D, Strobel, S.A. 登録日 2011-10-27 公開日 2012-01-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and biochemical characterization of linear dinucleotide analogues bound to the c-di-GMP-I aptamer. Biochemistry, 51, 2012
3UD3	The C92U mutant c-di-GMP-I riboswitch bound to pGpA 分子名称: MAGNESIUM ION, RNA (5'-R(P*GP*A)-3'), RNA (92-MER), ... 著者 Smith, K.D, Strobel, S.A. 登録日 2011-10-27 公開日 2012-01-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural and biochemical characterization of linear dinucleotide analogues bound to the c-di-GMP-I aptamer. Biochemistry, 51, 2012
3UCZ	The c-di-GMP-I riboswitch bound to GpG 分子名称: MAGNESIUM ION, RNA (5'-R(*GP*G)-3'), RNA (92-MER), ... 著者 Smith, K.D, Strobel, S.A. 登録日 2011-10-27 公開日 2012-01-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and biochemical characterization of linear dinucleotide analogues bound to the c-di-GMP-I aptamer. Biochemistry, 51, 2012
3UCU	The c-di-GMP-I riboswitch bound to pGpG 分子名称: MAGNESIUM ION, RNA (92-MER), U1 small nuclear ribonucleoprotein A, ... 著者 Smith, K.D, Strobel, S.A. 登録日 2011-10-27 公開日 2012-01-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and biochemical characterization of linear dinucleotide analogues bound to the c-di-GMP-I aptamer. Biochemistry, 51, 2012
5BTP	Fusobacterium ulcerans ZTP riboswitch bound to ZMP 分子名称: AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, MAGNESIUM ION, POTASSIUM ION, ... 著者 Jones, C.P, Ferre-D'Amare, A.R. 登録日 2015-06-03 公開日 2015-08-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.816 Å) 主引用文献 Recognition of the bacterial alarmone ZMP through long-distance association of two RNA subdomains. Nat.Struct.Mol.Biol., 22, 2015
7TZR	Crystal structure of the E. coli thiM riboswitch bound to N-methyl-1-(quinoxalin-6-yl)methanamine (compound 16) 分子名称: MAGNESIUM ION, N-methyl-1-(quinoxalin-6-yl)methanamine, POTASSIUM ION, ... 著者 Nuthanakanti, A, Serganov, A. 登録日 2022-02-16 公開日 2022-05-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 SHAPE-enabled fragment-based ligand discovery for RNA. Proc.Natl.Acad.Sci.USA, 119, 2022
7TZS	Crystal structure of the E. coli thiM riboswitch in complex with quinoxalin-6-ylmethanamine (compound 17) 分子名称: 1-(quinoxalin-6-yl)methanamine, MAGNESIUM ION, POTASSIUM ION, ... 著者 Nuthanakanti, A, Serganov, A. 登録日 2022-02-16 公開日 2022-05-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 SHAPE-enabled fragment-based ligand discovery for RNA. Proc.Natl.Acad.Sci.USA, 119, 2022

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