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7VZ8
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Membrane arm of deactive state CI from Q1-NADH dataset
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ...
著者Gu, J, Yang, M.
登録日2021-11-15
公開日2022-12-28
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
7VZ1
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Matrix arm of deactive state CI from Q1-NADH dataset
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Gu, J, Yang, M.
登録日2021-11-15
公開日2022-12-28
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
7OCA
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Resting state full-length GluA1/A2 heterotertramer in complex with TARP gamma 8 and CNIH2
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H.
登録日2021-04-26
公開日2021-06-09
最終更新日2021-06-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
5W5O
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Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases.
分子名称: 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine, Receptor-interacting serine/threonine-protein kinase 2
著者Kreusch, A, Spraggon, G.
登録日2017-06-15
公開日2017-10-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.
ACS Med Chem Lett, 8, 2017
7W1O
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Deactive state CI from Q10-NADH dataset, Subclass 1
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Gu, J.K, Yang, M.J.
登録日2021-11-19
公開日2022-12-21
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
7W1P
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Deactive state CI from Q10-NADH dataset, Subclass 2
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Gu, J.K, Yang, M.J.
登録日2021-11-19
公開日2022-12-28
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
7OF6
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Structure of mature human mitochondrial ribosome large subunit in complex with GTPBP6 (PTC conformation 2).
分子名称: 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ...
著者Hillen, H.S, Lavdovskaia, E, Nadler, F, Hanitsch, E, Linden, A, Bohnsack, K.E, Urlaub, H, Richter-Dennerlein, R.
登録日2021-05-04
公開日2021-06-09
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Nat Commun, 12, 2021
7OF5
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Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with MTERF4-NSUN4 and GTPBP5 (dataset2).
分子名称: 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ...
著者Hillen, H.S, Lavdovskaia, E, Nadler, F, Hanitsch, E, Linden, A, Bohnsack, K.E, Urlaub, H, Richter-Dennerlein, R.
登録日2021-05-04
公開日2021-06-09
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Nat Commun, 12, 2021
7WCA
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CATPO mutant - E484A
分子名称: CALCIUM ION, Catalase, PENTAETHYLENE GLYCOL, ...
著者Yuzugullu Karakus, Y, Balci Unver, S, Zengin Karatas, M, Goc, G, Pearson, A.R, Yorke, B.
登録日2021-12-18
公開日2022-12-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Investigation of how gate residues in the main channel affect the catalytic activity of Scytalidium thermophilum catalase.
Acta Crystallogr D Struct Biol, 80, 2024
7VZR
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Structure of the Acidobacteria homodimeric reaction center bound with cytochrome c (the smaller form)
分子名称: BACTERIOCHLOROPHYLL A, CALCIUM ION, CHLOROPHYLL A, ...
著者Huang, G.Q, Dong, S.S, Qin, X.C, Sui, S.F.
登録日2021-11-16
公開日2022-12-28
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.22 Å)
主引用文献Structure of the Acidobacteria homodimeric reaction center bound with cytochrome c
Nat Commun, 13, 2022
7WGX
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SARS-CoV-2 spike glycoprotein trimer in closed state after treatment with Cathepsin L
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ...
著者Zhu, Y, Tai, L, Yin, G, Sun, F.
登録日2021-12-29
公開日2023-01-04
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies
Cell Discov, 8, 2022
7WGV
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BU of 7wgv by Molmil
SARS-CoV-2 spike glycoprotein trimer in closed state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ...
著者Zhu, Y, Tai, L, Yin, G, Sun, F.
登録日2021-12-29
公開日2023-01-04
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies
Cell Discov, 8, 2022
7W4M
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BU of 7w4m by Molmil
Deactive state CI from Q1-NADH dataset, Subclass 4
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Gu, J, Yang, M.
登録日2021-11-28
公開日2023-01-25
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
7W4L
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BU of 7w4l by Molmil
Deactive state CI from Q1-NADH dataset, Subclass 3
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Gu, J, Yang, M.
登録日2021-11-28
公開日2023-01-25
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
5WS6
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BU of 5ws6 by Molmil
Native XFEL structure of Photosystem II (preflash two-flash dataset
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Suga, M, Shen, J.R.
登録日2016-12-05
公開日2017-03-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Light-induced structural changes and the site of O=O bond formation in PSII caught by XFEL.
Nature, 543, 2017
7W1Z
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Active state CI from Rotenone-NADH dataset, Subclass 2
分子名称: (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ...
著者Gu, J.K, Yang, M.J.
登録日2021-11-21
公開日2023-01-18
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
2AH9
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Crystal Structure of Human M340H-Beta-1,4-Galactosyltransferase-I (M340H-B4Gal-T1) in Complex with Chitotriose
分子名称: 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ramasamy, V, Ramakrishnan, B, Boeggeman, E, Ratner, D.M, Seeberger, P.H, Qasba, P.K.
登録日2005-07-27
公開日2005-10-04
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety
J.Mol.Biol., 353, 2005
7WHB
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SARS-CoV-2 spike in complex with the ZB8 neutralizing antibody Fab (3U)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Zeng, J.W, Ge, J.W, Wang, X.Q.
登録日2021-12-30
公開日2023-01-18
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.67 Å)
主引用文献SARS-CoV-2 hijacks neutralizing dimeric IgA for nasal infection and injury in Syrian hamsters 1 .
Emerg Microbes Infect, 12, 2023
5WDA
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Structure of the PulG pseudopilus
分子名称: CALCIUM ION, General secretion pathway protein G
著者Lopez-Castilla, A, Thomassin, J.L, Bardiaux, B, Zheng, W, Nivaskumar, M, Yu, X, Nilges, M, Egelman, E.H, Izadi-Pruneyre, N, Francetic, O.
登録日2017-07-04
公開日2017-10-25
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structure of the calcium-dependent type 2 secretion pseudopilus.
Nat Microbiol, 2, 2017
7WM4
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Cryo-EM structure of tetrameric TLR3 in complex with dsRNA (90 bp)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (81-MER), ...
著者Sakaniwa, K, Ohto, U, Shimizu, T.
登録日2022-01-14
公開日2023-01-25
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction.
Nat Commun, 14, 2023
7W4N
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Deactive state CI from Q1-NADH dataset, Subclass 5
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Gu, J, Yang, M.
登録日2021-11-28
公開日2023-01-25
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
5WYF
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Structure of amino acid racemase, 2.12 A
分子名称: CADMIUM ION, Isoleucine 2-epimerase, N-[O-PHOSPHONO-PYRIDOXYL]-ISOLEUCINE
著者Sakuraba, H, Mutaguchi, Y, Hayashi, J, Ohshima, T.
登録日2017-01-12
公開日2017-04-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Crystal structure of the novel amino-acid racemase isoleucine 2-epimerase from Lactobacillus buchneri.
Acta Crystallogr D Struct Biol, 73, 2017
7W4G
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Active state CI from Q1-NADH dataset, Subclass 5
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Gu, J, Yang, M.
登録日2021-11-27
公開日2023-01-25
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
7W1V
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Active state CI from Rotenone-NADH dataset, Subclass 1
分子名称: (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ...
著者Gu, J.K, Yang, M.J.
登録日2021-11-20
公開日2023-01-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
5W7B
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Rabbit acyloxyacyl hydrolase (AOAH), proteolytically processed, S262A mutant, with LPS
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gorelik, A, Illes, K, Nagar, B.
登録日2017-06-19
公開日2018-01-03
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the mammalian lipopolysaccharide detoxifier.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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