PDB: 215264 件ウェブページステータス検索Chemie searchBIRD

---

6DAX	X-ray crystal structure of VioC bound to Fe(II), L-homoarginine, and 2-oxoglutarate 分子名称: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent L-arginine hydroxylase, FE (II) ION, ... 著者 Dunham, N.P, Mitchell, A.J, Boal, A.K. 登録日 2018-05-02 公開日 2018-05-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of alpha-Heteroatom Assistance. J. Am. Chem. Soc., 140, 2018
5XEW	Crystal structure of the [Ni2+-(chromomycin A3)2]-CCG repeats complex 分子名称: (1S)-5-deoxy-1-O-methyl-1-C-[(2R,3S)-3,5,7,10-tetrahydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-D-xylulose, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-(2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol, ... 著者 Tseng, W.H, Wu, P.C, Hou, M.H. 登録日 2017-04-06 公開日 2017-06-21 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Induced-Fit Recognition of CCG Trinucleotide Repeats by a Nickel-Chromomycin Complex Resulting in Large-Scale DNA Deformation Angew. Chem. Int. Ed. Engl., 56, 2017
4X4C	RADIATION DAMAGE TO THE NUCLEOPROTEIN COMPLEX C.Esp1396I: DOSE (DWD) 6.2 MGy 分子名称: 35-MER DNA, Regulatory protein 著者 Bury, C.S, McGeehan, J.E, Garman, E.F. 登録日 2014-12-02 公開日 2015-03-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Radiation damage to nucleoprotein complexes in macromolecular crystallography. J.Synchrotron Radiat., 22, 2015
8IEI	Cryo-EM structure of GPR156A/B of G-protein free GPR156 (local refine) 分子名称: Probable G-protein coupled receptor 156, [(2R)-3-[(E)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate 著者 Shin, J, Park, J, Cho, Y. 登録日 2023-02-15 公開日 2024-02-14 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.62 Å) 主引用文献 Constitutive activation mechanism of a class C GPCR. Nat.Struct.Mol.Biol., 31, 2024
6S0B	Crystal Structure of Properdin in complex with the CTC domain of C3/C3b 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Properdin, ... 著者 van den Bos, R.M, Pearce, N.M, Gros, P. 登録日 2019-06-14 公開日 2019-09-04 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.312 Å) 主引用文献 Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b. Front Immunol, 10, 2019
8IEB	Cryo-EM structure of GPR156 of GPR156-miniGo-scFv16 complex (local refine) 分子名称: Probable G-protein coupled receptor 156, [(2R)-3-[(E)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate 著者 Shin, J, Park, J, Cho, Y. 登録日 2023-02-15 公開日 2024-02-14 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.03 Å) 主引用文献 Constitutive activation mechanism of a class C GPCR. Nat.Struct.Mol.Biol., 31, 2024
4XJC	dCTP deaminase-dUTPase from Bacillus halodurans 分子名称: DI(HYDROXYETHYL)ETHER, Deoxycytidine triphosphate deaminase, MAGNESIUM ION, ... 著者 Oehlenschlaeger, C, Loevgreen, M, Willemoes, M, Harris, P. 登録日 2015-01-08 公開日 2015-03-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Bacillus halodurans Strain C125 Encodes and Synthesizes Enzymes from Both Known Pathways To Form dUMP Directly from Cytosine Deoxyribonucleotides. Appl.Environ.Microbiol., 81, 2015
8PM0	Influenza A/H7N9 polymerase in replicase-like conformation in pre-initiation state with Pol II pS5 CTD peptide mimic bound in site 1A/2A 分子名称: 51-mer vRNA loop (v51_mut_S), MAGNESIUM ION, Polymerase acidic protein, ... 著者 Arragain, B, Cusack, S. 登録日 2023-06-27 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
6O5E	Crystal structure of the Vitronectin hemopexin-like domain 分子名称: CHLORIDE ION, IMIDAZOLE, NITRATE ION, ... 著者 Lechtenberg, B.C, Shin, K, Marassi, F.M. 登録日 2019-03-01 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of human Vitronectin C-terminal domain and interaction withYersinia pestisouter membrane protein Ail. Sci Adv, 5, 2019
4XHV	Crystal structure of Drosophila Spinophilin-PDZ and a C-terminal peptide of Neurexin 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, LP20995p, ... 著者 Driller, J.H, Muhammad, K.G.H, Reddy, S, Rey, U, Boehme, M.A, Hollmann, C, Ramesh, N, Depner, H, Luetzkendorf, J, Matkovic, T, Bergeron, D, Quentin, C, Schmoranzer, J, Goettfert, F, Holt, M, Wahl, M.C, Hell, S.W, Walter, A, Sigrist, S.J, Loll, B. 登録日 2015-01-06 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function. Nat Commun, 6, 2015
6ZSK	Cytochrome c prime beta from Methylococcus capsulatus (Bath): CO complex 分子名称: CARBON MONOXIDE, Cytochrome c, GLYCEROL, ... 著者 Adams, H.R, Hough, M.A. 登録日 2020-07-15 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 to be published To Be Published
1OGY	Crystal structure of the heterodimeric nitrate reductase from Rhodobacter sphaeroides 分子名称: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, DIHEME CYTOCHROME C NAPB MOLECULE: NITRATE REDUCTASE, HEME C, ... 著者 Arnoux, P, Sabaty, M, Alric, J, Frangioni, B, Guigliarelli, B, Adriano, J.-M, Pignol, D. 登録日 2003-05-19 公開日 2003-10-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural and Redox Plasticity in the Heterodimeric Periplasmic Nitrate Reductase Nat.Struct.Biol., 10, 2003
4XOQ	F420 complex of coenzyme F420:L-glutamate ligase (FbiB) from Mycobacterium tuberculosis (C-terminal domain) 分子名称: COENZYME F420, Coenzyme F420:L-glutamate ligase, SULFATE ION 著者 Rehan, A.M, Bashiri, G, Baker, H.M, Baker, E.N, Squire, C.J. 登録日 2015-01-16 公開日 2016-02-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Elongation of the Poly-gamma-glutamate Tail of F420 Requires Both Domains of the F420: gamma-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis. J.Biol.Chem., 291, 2016
8S94	Structure of C-terminal domains of Walker B mutated MCM8/9 heterohexamer complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA helicase MCM8, DNA helicase MCM9, ... 著者 Li, C, Gao, Y. 登録日 2023-03-27 公開日 2023-06-07 最終更新日 2023-08-23 実験手法 ELECTRON MICROSCOPY (3.94 Å) 主引用文献 Activity, substrate preference and structure of the HsMCM8/9 helicase. Nucleic Acids Res., 51, 2023
6V9K	CRYSTAL STRUCTURE OF THE HYBRID C-TERMINAL DOMAIN OF ENZYME I OF THE BACTERIAL PHOSPHOTRANSFERASE SYSTEM FORMED BY HYBRIDIZING THE SCAFFOLD OF THE ESCHERICHIA COLI ENZYME WITH THE ACTIVE SITE LOOPS FROM THE THERMOANAEROBACTER TENGCONGENSIS ENZYME 分子名称: MAGNESIUM ION, Phosphoenolpyruvate-protein phosphotransferase 著者 Stewart Jr, C.E. 登録日 2019-12-13 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Hybrid Thermophilic/Mesophilic Enzymes Reveal a Role for Conformational Disorder in Regulation of Bacterial Enzyme I. J.Mol.Biol., 432, 2020
6OTL	Structure of Aedes aegypti OBP22 in the complex with benzaldehyde 分子名称: AAEL005772-PA, BENZOIC ACID, HEXATANTALUM DODECABROMIDE, ... 著者 Jones, D.N, Murphy, E. 登録日 2019-05-03 公開日 2019-06-12 最終更新日 2020-05-06 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail. Sci Rep, 10, 2020
4Q6Z	LpoB C-terminal domain from Escherichia coli 分子名称: Penicillin-binding protein activator LpoB 著者 King, D.T, Strynadka, N.C.J. 登録日 2014-04-23 公開日 2014-05-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural Insights into the Lipoprotein Outer Membrane Regulator of Penicillin-binding Protein 1B. J.Biol.Chem., 289, 2014
6P2E	Structure of Aedes aegypti OBP22 in the complex with benzaldehyde 分子名称: BENZOIC ACID, GLYCEROL, OBP22, ... 著者 Jones, D.N, Murphy, E. 登録日 2019-05-21 公開日 2019-07-31 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail. Sci Rep, 10, 2020
5TJ5	Atomic model for the membrane-embedded motor of a eukaryotic V-ATPase 分子名称: V-type proton ATPase subunit a, V-type proton ATPase subunit c, V-type proton ATPase subunit c', ... 著者 Mazhab-Jafari, M.T, Rohou, A, Schmidt, C, Bueler, S.A, Benlekbir, S, Robinson, C.V, Rubinstein, J.L. 登録日 2016-10-03 公開日 2016-10-26 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase. Nature, 539, 2016
8IUG	Cryo-EM structure of the RC-LH core complex from roseiflexus castenholzii 分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-O-octyl-beta-D-glucopyranose, ... 著者 Wang, G.-L, Qi, C.-H, Yu, L.-J. 登録日 2023-03-24 公開日 2023-11-22 最終更新日 2023-12-06 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 New insights on the photocomplex of Roseiflexus castenholzii revealed from comparisons of native and carotenoid-depleted complexes. J.Biol.Chem., 299, 2023
4XX5	Structure of PI3K gamma in complex with an inhibitor 分子名称: N-[5-(5-methoxypyridin-3-yl)-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl]acetamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 著者 Collier, P.N, Messersmith, D, Le Tiran, A, Bandarage, U.K, Boucher, C, Come, J, Cottrell, K.M, Damagnez, V, Doran, J.D, Griffith, J.P, Khare-Pandit, S, Krueger, E.B, Ledeboer, M.W, Ledford, B, Liao, Y, Mahajan, S, Moody, C.S, Wang, T, Xu, J, Aronov, A.M. 登録日 2015-01-29 公開日 2015-08-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Structure of PI3K gamma in complex with an inhibitor To Be Published
4XZ4	Structure of PI3K gamma in complex with an inhibitor 分子名称: N-[5-(6-methoxypyrazin-2-yl)-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl]acetamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 著者 Collier, P.N, Messersmith, D, Le Tiran, A, Bandarage, U.K, Boucher, C, Come, J, Cottrell, K.M, Damagnez, V, Doran, J.D, Griffith, J.P, Khare-Pandit, S, Krueger, E.B, Ledeboer, M.W, Ledford, B, Liao, Y, Mahajan, S, Moody, C.S, Wang, T, Xu, J, Aronov, A.M. 登録日 2015-02-03 公開日 2016-02-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of PI3K gamma in complex with an inhibitor To Be Published
1FD0	ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARGAMMA-SELECTIVE RETINOID SR11254 分子名称: 6-[HYDROXYIMINO-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALEN-2-YL)-METHYL]-NAPHTALENE-2-CARBOXYLIC ACID, DODECYL-ALPHA-D-MALTOSIDE, RETINOIC ACID RECEPTOR GAMMA-1 著者 Klaholz, B.P, Moras, D, Structural Proteomics in Europe (SPINE) 登録日 2000-07-19 公開日 2002-09-27 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 C-H...O hydrogen bonds in the nuclear receptor RARgamma--a potential tool for drug selectivity. Structure, 10, 2002
5FTQ	Crystal structure of the ALK kinase domain in complex with Cmpd 17 分子名称: ALK TYROSINE KINASE RECEPTOR, GLYCEROL, N-[5-(3,5-DIFLUOROBENZYL)-1H-INDAZOL-3-YL]-2-[(4-HYDROXYCYCLOHEXYL)AMINO]-4-(4-METHYLPIPERAZIN-1-YL) BENZAMIDE 著者 Bossi, R, Canevari, G, Fasolini, M, Menichincheri, M, Ardini, E, Magnaghi, P, Avanzi, N, Banfi, P, Buffa, L, Ceriani, L, Colombo, M, Corti, L, Donati, D, Felder, E, Fiorelli, C, Fiorentini, F, Galvani, A, Isacchi, A, Lombardi Borgia, A, Marchionni, C, Nesi, M, Orrenius, C, Panzeri, A, Perrone, E, Pesenti, E, Rusconi, L, Saccardo, M.B, Vanotti, E, Orsini, P. 登録日 2016-01-14 公開日 2016-04-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery of Entrectinib: A New 3-Aminoindazole as a Potent Anaplastic Lymphoma Kinase (Alk), C-Ros Oncogene 1 Kinase (Ros1), and Pan-Tropomyosin Receptor Kinases (Pan-Trks) Inhibitor. J.Med.Chem., 59, 2016
8D1P	Crystal structure of Plasmodium falciparum GRP78-NBD in complex with 7-Deaza-2'-C-methyladenosine 分子名称: 7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Chaperone DnaK, SULFATE ION 著者 Mrozek, A, Chen, Y, Antoshchenko, T, Park, H.W. 登録日 2022-05-27 公開日 2023-05-31 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 A non-traditional crystal-based compound screening method targeting the ATP binding site of Plasmodium falciparum GRP78 for identification of novel nucleoside analogues. Front Mol Biosci, 9, 2022

<131132133134135136137138139140141142143144145146>