PDB: 46054 件ウェブページステータス検索Chemie searchBIRD

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4I0P	HLA-DO in complex with HLA-DM 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, GLYCEROL, ... 著者 Guce, A.I, Mortimer, S.E, Stern, L.J. 登録日 2012-11-18 公開日 2012-12-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism. Nat.Struct.Mol.Biol., 20, 2013
3D8U	The crystal structure of a PurR family transcriptional regulator from Vibrio parahaemolyticus RIMD 2210633 分子名称: PurR transcriptional regulator 著者 Tan, K, Hatzos, C, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2008-05-23 公開日 2008-07-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 The crystal structure of a PurR family transcriptional regulator from Vibrio parahaemolyticus RIMD 2210633 To be Published
3D90	Crystal structure of the human progesterone receptor ligand-binding domain bound to levonorgestrel 分子名称: 13-BETA-ETHYL-17-ALPHA-ETHYNYL-17-BETA-HYDROXYGON-4-EN-3-ONE, Progesterone receptor 著者 Petit-Topin, I, Turque, N, Ulman, A, Gainer, E, Rafestin-Oblin, M.E, Fagart, J. 登録日 2008-05-26 公開日 2009-05-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Met909 plays a key role in the activation of the progesterone receptor and also in the high potency of 13-ethyl progestins Mol.Pharmacol., 75, 2009
4E47	SET7/9 in complex with inhibitor (R)-(3-(3-cyanophenyl)-1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6- sulfonamide and S-adenosylmethionine 分子名称: (R)-(3-(3-cyanophenyl)-1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide, BETA-MERCAPTOETHANOL, Histone-lysine N-methyltransferase SETD7, ... 著者 Walker, J.R, Ouyang, H, Dong, A, Fish, P, Cook, A, Barsyte, D, Vedadi, M, Tatlock, J, Owen, D, Bunnage, M, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Brown, P.J, Structural Genomics Consortium (SGC) 登録日 2012-03-12 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Setd7 in Complex with Inhibitor and SAM To be Published
1WJQ	Solution structure of the third mbt domain from human KIAA1798 protein 分子名称: KIAA1798 protein 著者 Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-29 公開日 2004-11-29 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the third mbt domain from human KIAA1798 protein To be Published
2QY2	Characterization of a trifunctional mimivirus mRNA capping enzyme and crystal structure of the RNA triphosphatase domainm. 分子名称: ACETATE ION, CITRATE ANION, Probable mRNA-capping enzyme 著者 Shuman, S, Benarroch, D, Smith, P. 登録日 2007-08-13 公開日 2008-04-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Characterization of a trifunctional mimivirus mRNA capping enzyme and crystal structure of the RNA triphosphatase domain. Structure, 16, 2008
3DAC	Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain 分子名称: Cellular tumor antigen p53, Mdm4 protein 著者 Popowicz, G.M, Czarna, A, Holak, T.A. 登録日 2008-05-29 公開日 2008-09-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain. Cell Cycle, 7, 2008
4IAN	Crystal Structure of apo Human PRPF4B kinase domain 分子名称: SULFATE ION, Serine/threonine-protein kinase PRP4 homolog 著者 Mechin, I, Haas, K, Chen, X, Zhang, Y, McLean, L. 登録日 2012-12-06 公開日 2013-08-28 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches. J.Biol.Chem., 288, 2013
3E7C	Glucocorticoid Receptor LBD bound to GSK866 分子名称: 5-amino-N-[(2S)-2-({[(2,6-dichlorophenyl)carbonyl](ethyl)amino}methyl)-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide, GLYCEROL, Glucocorticoid receptor, ... 著者 Madauss, K.P, Williams, S.P, Mclay, I, Stewart, E.L, Bledsoe, R.K. 登録日 2008-08-18 公開日 2008-11-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The first X-ray crystal structure of the glucocorticoid receptor bound to a non-steroidal agonist. Bioorg.Med.Chem.Lett., 18, 2008
4MBJ	Human B-Raf Kinase Domain in Complex with an Imidazopyridine-based Inhibitor 分子名称: 2,6-difluoro-N-(1H-imidazo[4,5-b]pyridin-6-yl)-3-[(propylsulfonyl)amino]benzamide, Serine/threonine-protein kinase B-raf 著者 Voegtli, W.C. 登録日 2013-08-19 公開日 2013-10-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Imidazo[4,5-b]pyridine inhibitors of B-Raf kinase. Bioorg.Med.Chem.Lett., 23, 2013
4MLE	Human Glucokinase in Complex with Novel Amino Thiazole Activator 分子名称: 3-(benzyloxy)-N-(4-methyl-1,3-thiazol-2-yl)pyridin-2-amine, Glucokinase, alpha-D-glucopyranose 著者 Voegtli, W.C. 登録日 2013-09-06 公開日 2013-09-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Identification of a New Class of Glucokinase Activators through Structure-Based Design. J.Med.Chem., 56, 2013
4I15	Crystal structure of TbrPDEB1 分子名称: Class 1 phosphodiesterase PDEB1, MAGNESIUM ION, ZINC ION 著者 Wang, H, Ke, H. 登録日 2012-11-20 公開日 2013-03-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Discovery of Novel Trypanosoma brucei Phosphodiesterase B1 Inhibitors by Virtual Screening against the Unliganded TbrPDEB1 Crystal Structure. J.Med.Chem., 56, 2013
4EDU	The MBT repeats of human SCML2 in a complex with histone H2A peptide 分子名称: Histone H2A.J peptide, Sex comb on midleg-like protein 2 著者 Nady, N, Amaya, M.F, Tempel, W, Ravichandran, M, Arrowsmith, C.H. 登録日 2012-03-27 公開日 2012-09-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Histone recognition by human malignant brain tumor domains. J.Mol.Biol., 423, 2012
4I2W	Crystal structure of the myosin chaperone UNC-45 from C.elegans in complex with a Hsp70 peptide 分子名称: Heat shock 70 kDa protein A, Protein UNC-45 著者 Clausen, T, Gazda, L, Hellerschmied, D. 登録日 2012-11-23 公開日 2013-03-13 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 The myosin chaperone UNC-45 is organized in tandem modules to support myofilament formation in C. elegans. Cell(Cambridge,Mass.), 152, 2013
2Z5S	Molecular basis for the inhibition of p53 by Mdmx 分子名称: Cellular tumor antigen p53, Mdm4 protein 著者 Popowicz, G.M, Czarna, A, Rothweiler, U, Szwagierczak, A, Holak, T.A. 登録日 2007-07-17 公開日 2007-11-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular basis for the inhibition of p53 by Mdmx. Cell Cycle, 6, 2007
4MLH	Human Glucokinase in Complex with a Novel Amino Thiazole Allosteric Activator 分子名称: 3-(benzyloxy)-5-methyl-N-(4-methyl-1,3-thiazol-2-yl)pyridin-2-amine, Glucokinase, alpha-D-glucopyranose 著者 Voegtli, W.C. 登録日 2013-09-06 公開日 2013-09-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Identification of a New Class of Glucokinase Activators through Structure-Based Design. J.Med.Chem., 56, 2013
4I99	Crystal structure of the SmcHead bound to the C-winged helix domain of ScpA 分子名称: Chromosome partition protein Smc, PHOSPHATE ION, Putative uncharacterized protein 著者 Shin, H.C, Soh, Y.M, Oh, B.H. 登録日 2012-12-05 公開日 2013-01-30 最終更新日 2017-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 An asymmetric SMC-kleisin bridge in prokaryotic condensin. Nat.Struct.Mol.Biol., 20, 2013
7WH4	Crystal structure of the PadR-family transcriptional regulator Rv3488 of Mycobacterium tuberculosis H37Rv in complex with Manganese ion 分子名称: MANGANESE (II) ION, Transcriptional regulator Rv3488 著者 Arora, A, Zohib, M, Biswal, B.K, Pal, R.K. 登録日 2021-12-29 公開日 2022-02-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of PadR-family transcriptional regulator Rv3488 of Mycobacterium tuberculosis H37Rv in complex with Manganese ion To Be Published
2Z5T	Molecular basis for the inhibition of p53 by Mdmx 分子名称: Cellular tumor antigen p53, Mdm4 protein 著者 Popowicz, G.M, Czarna, A, Rothweiler, U, Szwagierczak, A, Holak, T.A. 登録日 2007-07-17 公開日 2007-11-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular basis for the inhibition of p53 by Mdmx. Cell Cycle, 6, 2007
3E4U	Crystal Structure of the Wild-Type Human BCL6 BTB/POZ Domain 分子名称: B-cell lymphoma 6 protein 著者 Stead, M.A, Rosbrook, G.O, Hadden, J.M, Trinh, C.H, Carr, S.B, Wright, S.C. 登録日 2008-08-12 公開日 2008-12-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the wild-type human BCL6 POZ domain. Acta Crystallogr.,Sect.F, 64, 2008
2ZKC	Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with bisphenol Z 分子名称: 4,4'-cyclohexane-1,1-diyldiphenol, Estrogen-related receptor gamma, GLYCEROL 著者 Matsushima, A, Kakuta, Y, Teramoto, T, Shimohigashi, Y. 登録日 2008-03-14 公開日 2009-03-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with bisphenol Z To be Published
3E2S	Crystal Structure Reduced PutA86-630 Mutant Y540S Complexed with L-proline 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, PROLINE, ... 著者 Tanner, J.J. 登録日 2008-08-06 公開日 2009-02-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A conserved active site tyrosine residue of proline dehydrogenase helps enforce the preference for proline over hydroxyproline as the substrate. Biochemistry, 48, 2009
4EW7	The crystal structure of conjugative transfer PAS_like domain from Salmonella enterica subsp. enterica serovar Typhimurium 分子名称: ACETIC ACID, CHLORIDE ION, Conjugative transfer: regulation, ... 著者 Wu, R, Jedrzejczak, R.P, Brown, R.N, Cort, J.R, Heffron, F, Nakayasu, E.S, Adkins, J.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP) 登録日 2012-04-26 公開日 2012-09-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 The crystal structure of conjugative transfer PAS_like domain from Salmonella enterica subsp. enterica serovar Typhimurium To be Published
1WJR	Solution structure of the 2nd mbt domain from human KIAA1617 protein 分子名称: KIAA1617 protein 著者 Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-29 公開日 2004-11-29 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the 2nd mbt domain from human KIAA1617 protein To be Published
4I9H	Crystal structure of rabbit LDHA in complex with AP28669 分子名称: 1-O-[3-(5-carboxypyridin-2-yl)-5-fluorophenyl]-6-O-[4-({[(5-carboxypyridin-2-yl)sulfanyl]acetyl}amino)-2-chloro-5-methoxyphenyl]-D-mannitol, L-lactate dehydrogenase A chain 著者 Zhou, T, Stephan, Z.G, Kohlmann, A, Li, F, Commodore, L, Greenfield, M.T, Shakespeare, W.C, Zhu, X, Dalgarno, D.C. 登録日 2012-12-05 公開日 2013-01-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors. J.Med.Chem., 56, 2013

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