5ZNM
 
 | | Colicin D Central Domain and C-terminal tRNase domain | | 分子名称: | Colicin-D, GLYCEROL, SULFATE ION | | 著者 | Chang, J.W, Sato, Y, Ogawa, T, Arakawa, T, Fukai, S, Fushinobu, S, Masaki, H. | | 登録日 | 2018-04-10 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of the central and the C-terminal RNase domains of colicin D implicated its translocation pathway through inner membrane of target cell
J. Biochem., 164, 2018
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6PUE
 | | Structure of human MAIT A-F7 TCR in complex with human MR1-4'D-5-OP-RU | | 分子名称: | 1,4-dideoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-erythro-pentitol, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Awad, W, Rossjohn, J. | | 登録日 | 2019-07-18 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The molecular basis underpinning the potency and specificity of MAIT cell antigens.
Nat.Immunol., 21, 2020
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7RTE
 | | X-ray structure of wild type RBPJ-L3MBTL3-DNA complex | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*CP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), ... | | 著者 | Hall, D.P, Kovall, R.A, Yuan, Z. | | 登録日 | 2021-08-13 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | The structure, binding and function of a Notch transcription complex involving RBPJ and the epigenetic reader protein L3MBTL3.
Nucleic Acids Res., 50, 2022
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3M3Q
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7YMV
 | | Cryo-EM structure of MERS-CoV spike protein, Two RBD-up conformation 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Hsu, S.T.D, Chang, N.E, Weng, Z.W, Yang, T.J, Draczkowski, P. | | 登録日 | 2022-07-29 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (6.74 Å) | | 主引用文献 | Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Cell, 187, 2024
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6Q0S
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7YMW
 | | Cryo-EM structure of MERS-CoV spike protein, One RBD-up conformation 4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Hsu, S.T.D, Chang, N.E, Weng, Z.W, Yang, T.J, Draczkowski, P. | | 登録日 | 2022-07-29 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (6.05 Å) | | 主引用文献 | Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Cell, 187, 2024
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7YMX
 | | Cryo-EM structure of MERS-CoV spike protein, One RBD-up conformation 2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Hsu, S.T.D, Chang, N.E, Weng, Z.W, Yang, T.J, Draczkowski, P. | | 登録日 | 2022-07-29 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (4.44 Å) | | 主引用文献 | Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Cell, 187, 2024
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2SEB
 | | X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH A PEPTIDE FROM HUMAN COLLAGEN II | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENTEROTOXIN TYPE B, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ... | | 著者 | Dessen, A, Lawrence, C.M, Cupo, S, Zaller, D.M, Wiley, D.C. | | 登録日 | 1997-10-16 | | 公開日 | 1998-01-28 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II.
Immunity, 7, 1997
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7YMT
 | | Cryo-EM structure of MERS-CoV spike protein, Two RBD-up conformation 2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Hsu, S.T.D, Chang, N.E, Weng, Z.W, Yang, T.J, Draczkowski, P. | | 登録日 | 2022-07-29 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (6.55 Å) | | 主引用文献 | Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Cell, 187, 2024
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7YN0
 | | Cryo-EM structure of MERS-CoV spike protein, all RBD-down conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Hsu, S.T.D, Chang, N.E, Weng, Z.W, Yang, T.J, Draczkowski, P. | | 登録日 | 2022-07-29 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Cell, 187, 2024
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8RFE
 | | CgsiGP2 sample in nanodisc | | 分子名称: | Cyclic beta 1-2 glucan synthetase, URIDINE-5'-DIPHOSPHATE-GLUCOSE, beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose | | 著者 | Sedzicki, J, Ni, D, Lehmann, F, Stahlberg, H, Dehio, C. | | 登録日 | 2023-12-12 | | 公開日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure-function analysis of the cyclic beta-1,2-glucan synthase from Agrobacterium tumefaciens.
Nat Commun, 15, 2024
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7YMY
 | | Cryo-EM structure of MERS-CoV spike protein, One RBD-up conformation 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Hsu, S.T.D, Chang, N.E, Weng, Z.W, Yang, T.J, Draczkowski, P. | | 登録日 | 2022-07-29 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (4.96 Å) | | 主引用文献 | Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Cell, 187, 2024
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7YMZ
 | | Cryo-EM structure of MERS-CoV spike protein, intermediate conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Hsu, S.T.D, Chang, N.E, Weng, Z.W, Yang, T.J, Draczkowski, P. | | 登録日 | 2022-07-29 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (4.39 Å) | | 主引用文献 | Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.
Cell, 187, 2024
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4U93
 | | Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibitor NVP-HSP990 | | 分子名称: | (7R)-2-amino-7-[4-fluoro-2-(6-methoxypyridin-2-yl)phenyl]-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one, Heat shock protein HSP 90-alpha | | 著者 | Bellamacina, C.R, Shafer, C.M, Bussiere, D. | | 登録日 | 2014-08-05 | | 公開日 | 2014-11-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Design, Structure-Activity Relationship, and in Vivo Characterization of the Development Candidate NVP-HSP990.
J.Med.Chem., 57, 2014
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1SEU
 | | Human DNA Topoisomerase I (70 Kda) In Complex With The Indolocarbazole SA315F and Covalent Complex With A 22 Base Pair DNA Duplex | | 分子名称: | 2,10-DIHYDROXY-12-(BETA-D-GLUCOPYRANOSYL)-6,7,12,13-TETRAHYDROINDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE-5,7-DIONE, 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', ... | | 著者 | Staker, B.L, Feese, M.D, Cushman, M, Pommier, Y, Zembower, D, Stewart, L, Burgin, A.B. | | 登録日 | 2004-02-18 | | 公開日 | 2005-04-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex
J.Med.Chem., 48, 2005
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1J84
 | | STRUCTURE OF FAM17 CARBOHYDRATE BINDING MODULE FROM CLOSTRIDIUM CELLULOVORANS WITH BOUND CELLOTETRAOSE | | 分子名称: | CALCIUM ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, endo-1,4-beta glucanase EngF | | 著者 | Notenboom, V, Boraston, A.B, Chiu, P, Freelove, A.C.J, Kilburn, D.G, Rose, D.R. | | 登録日 | 2001-05-20 | | 公開日 | 2001-12-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Recognition of cello-oligosaccharides by a family 17 carbohydrate-binding module: an X-ray crystallographic, thermodynamic and mutagenic study.
J.Mol.Biol., 314, 2001
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5HNS
 | | Structure of glycosylated NPC1 luminal domain C | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Niemann-Pick C1 protein, ... | | 著者 | Zhao, Y, Ren, J, Harlos, K, Stuart, D.I. | | 登録日 | 2016-01-18 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure of glycosylated NPC1 luminal domain C reveals insights into NPC2 and Ebola virus interactions.
Febs Lett., 590, 2016
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1SL5
 | | Crystal Structure of DC-SIGN carbohydrate recognition domain complexed with LNFP III (Dextra L504). | | 分子名称: | CALCIUM ION, MAGNESIUM ION, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ... | | 著者 | Guo, Y, Feinberg, H, Conroy, E, Mitchell, D.A, Alvarez, R, Blixt, O, Taylor, M.E, Weis, W.I, Drickamer, K. | | 登録日 | 2004-03-05 | | 公開日 | 2004-06-15 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for distinct ligand-binding and targeting properties of the receptors
DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
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1S78
 | | Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab Fab heavy chain, ... | | 著者 | Franklin, M.C, Carey, K.D, Vajdos, F.F, Leahy, D.J, de Vos, A.M, Sliwkowski, M.X. | | 登録日 | 2004-01-29 | | 公開日 | 2004-04-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex.
Cancer Cell, 5, 2004
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5HVG
 | | Crystal Structure of Thrombin-activatable Fibrinolysis Inhibitor in Complex with an Inhibitory Nanobody (VHH-a204) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | 著者 | Zhou, X, Weeks, S.D, Strelkov, S.V, Declerck, P.J. | | 登録日 | 2016-01-28 | | 公開日 | 2016-06-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity.
J.Thromb.Haemost., 14, 2016
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7SOA
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7SO9
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7SOE
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7SOD
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