7KBU
 
 | | Structure of Hevin FS-EC | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Machius, M, Fan, S, Rudenko, G. | | 登録日 | 2020-10-03 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-07-14 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Interplay between hevin, SPARC, and MDGAs: Modulators of neurexin-neuroligin transsynaptic bridges.
Structure, 29, 2021
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7TS5
 | | Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-methyl-6-(3-(methylamino)prop-1-yn-1-yl)pyridin-2-amine | | 分子名称: | 4-methyl-6-[3-(methylamino)prop-1-yn-1-yl]pyridin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, GLYCEROL, ... | | 著者 | Li, H, Poulos, T.L. | | 登録日 | 2022-01-31 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | 2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.
Bioorg.Med.Chem., 69, 2022
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7PFY
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5LM7
 | | Crystal structure of the lambda N-Nus factor complex | | 分子名称: | 30S ribosomal protein S10, Antitermination protein N, N utilization substance protein B homolog, ... | | 著者 | Said, N, Santos, K, Weber, G, Wahl, M.C. | | 登録日 | 2016-07-29 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
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7PEK
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2XZZ
 | | Crystal structure of the human transglutaminase 1 beta-barrel domain | | 分子名称: | PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE K | | 著者 | Vollmar, M, Krysztofinska, E, Krojer, T, Yue, W.W, Cooper, C, Kavanagh, K, Allerston, C, Chaikuad, A, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U. | | 登録日 | 2010-11-30 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of the Human Transglutaminase 1 Beta-Barrel Domain
To be Published
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7TSH
 | | Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(3-(methylamino)propyl)pyridin-2-amine | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-methyl-6-[3-(methylamino)propyl]pyridin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, ... | | 著者 | Li, H, Poulos, T.L. | | 登録日 | 2022-01-31 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.145 Å) | | 主引用文献 | 2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.
Bioorg.Med.Chem., 69, 2022
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2NV5
 | | Crystal structure of a C-terminal phosphatase domain of Rattus norvegicus ortholog of human protein tyrosine phosphatase, receptor type, D (PTPRD) | | 分子名称: | PTPRD, PHOSPHATASE | | 著者 | Bonanno, J.B, Gilmore, J, Bain, K.T, Iizuka, M, Xu, W, Wasserman, S, Smith, D, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2006-11-10 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural genomics of protein phosphatases.
J.STRUCT.FUNCT.GENOM., 8, 2007
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7FV1
 | | PanDDA analysis group deposition -- PHIP in complex with Z4912742920 | | 分子名称: | PH-interacting protein, tert-butyl [3-({[4-(furan-2-carbonyl)piperazine-1-carbonyl]amino}methyl)phenyl]carbamate | | 著者 | Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. | | 登録日 | 2023-03-09 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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6ZMR
 | | Porcine ATP synthase Fo domain | | 分子名称: | ATP synthase F(0) complex subunit C1, mitochondrial, ATP synthase g subunit, ... | | 著者 | Spikes, T.E, Montgomery, M.G, Walker, J.E. | | 登録日 | 2020-07-03 | | 公開日 | 2020-09-09 | | 最終更新日 | 2020-09-30 | | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7PXV
 | | LsAA9_A chemically reduced with ascorbic acid (high X-ray dose) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Auxiliary activity 9, CHLORIDE ION, ... | | 著者 | Tandrup, T, Muderspach, S.J, Banerjee, S, Ipsen, J, Johansen, K.S, Lo Leggio, L. | | 登録日 | 2021-10-08 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Changes in active-site geometry on X-ray photoreduction of a lytic polysaccharide monooxygenase active-site copper and saccharide binding.
Iucrj, 9, 2022
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2Y0C
 | | BceC mutation Y10S | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLYCEROL, ... | | 著者 | Rocha, J, Popescu, A.O, Borges, P, Mil-Homens, D, Sa-Correia, I, Fialho, A.M, Frazao, C. | | 登録日 | 2010-12-02 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structure of Burkholderia Cepacia Udp-Glucose Dehydrogenase (Ugd) Bcec and Role of Tyr10 in Final Hydrolysis of Ugd Thioester Intermediate.
J.Bacteriol., 193, 2011
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7AAU
 | | Crystal structure of nitrosoglutathione reductase from Chlamydomonas reinhardtii in complex with NAD+ | | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | | 著者 | Fermani, S, Zaffagnini, M, Falini, G, Lemaire, S.D. | | 登録日 | 2020-09-04 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Structural and functional insights into nitrosoglutathione reductase from Chlamydomonas reinhardtii.
Redox Biol, 38, 2020
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7PEF
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7JZV
 | | Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome | | 分子名称: | BRCA1,Ubiquitin-conjugating enzyme E2 D3, BRCA1-associated RING domain protein 1, Histone H2A type 2-A, ... | | 著者 | Witus, S.R, Burrell, A.L, Hansen, J.M, Farrell, D.P, Dimaio, F, Kollman, J.M, Klevit, R.E. | | 登録日 | 2020-09-02 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.
Nat.Struct.Mol.Biol., 28, 2021
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7FVG
 | | PanDDA analysis group deposition -- PHIP in complex with Z992453336 | | 分子名称: | N-(4-methoxyphenyl)-4-(5-methylfuran-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein | | 著者 | Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. | | 登録日 | 2023-03-09 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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8PJ4
 | | Structure of human 48S translation initiation complex after eIF5 release (48S-4) | | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | | 登録日 | 2023-06-22 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining
Nat.Struct.Mol.Biol., 2024
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7FVL
 | | PanDDA analysis group deposition -- PHIP in complex with Z4140355932 | | 分子名称: | N-{[(2S)-5,5-dimethyl-1,4-dioxan-2-yl]methyl}-4-(3-hydroxybenzoyl)piperazine-1-carboxamide, PH-interacting protein | | 著者 | Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. | | 登録日 | 2023-03-09 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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3I10
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7TS3
 | | Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3,3-difluoroazetidin-1-yl)prop-1-yn-1-yl)-4-methylpyridin-2-amine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-[3-(3,3-difluoroazetidin-1-yl)prop-1-yn-1-yl]-4-methylpyridin-2-amine, GLYCEROL, ... | | 著者 | Li, H, Poulos, T.L. | | 登録日 | 2022-01-31 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | 2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.
Bioorg.Med.Chem., 69, 2022
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2ZGB
 | | Thrombin Inhibition | | 分子名称: | D-leucyl-N-(3-chlorobenzyl)-L-prolinamide, Hirudin variant-1, SODIUM ION, ... | | 著者 | Baum, B, Heine, A, Klebe, G. | | 登録日 | 2008-01-21 | | 公開日 | 2008-12-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Non-additivity of functional group contributions in protein-ligand binding: a comprehensive study by crystallography and isothermal titration calorimetry.
J.Mol.Biol., 397, 2010
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7FV2
 | | PanDDA analysis group deposition -- PHIP in complex with Z445899798 | | 分子名称: | N-(2-methoxyethyl)-4-(thiophene-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein | | 著者 | Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. | | 登録日 | 2023-03-09 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | PanDDA analysis group deposition
To Be Published
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2JBW
 | | Crystal Structure of the 2,6-dihydroxy-pseudo-oxynicotine Hydrolase. | | 分子名称: | 2,6-DIHYDROXY-PSEUDO-OXYNICOTINE HYDROLASE, SODIUM ION | | 著者 | Schleberger, C, Sachelaru, P, Brandsch, R, Schulz, G.E. | | 登録日 | 2006-12-14 | | 公開日 | 2007-01-04 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure and Action of a Cc Bond Cleaving Alpha/Beta-Hydrolase Involved in Nicotine Degration.
J.Mol.Biol., 367, 2007
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2K0M
 | | Solution NMR structure of the uncharacterized protein from Rhodospirillum rubrum gene locus Rru_A0810. Northeast Structural Genomics Target RrR43 | | 分子名称: | Uncharacterized protein | | 著者 | Rossi, P, Wang, H, Jiang, M, Foote, E.L, Xiao, R, Liu, J, Swapna, G, Acton, T.B, Baran, M.C, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2008-02-04 | | 公開日 | 2008-02-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of the uncharacterized protein from Rhodospirillum rubrum gene locus Rru_A0810. Northeast Structural Genomics Target RrR43.
To be Published
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7TTS
 | | Skd3, hexamer, filtered | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Beta-casein, Caseinolytic peptidase B protein homolog, ... | | 著者 | Rizo, A.N, Cupo, R.R. | | 登録日 | 2022-02-01 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3.
Cell Rep, 40, 2022
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