PDB: 10243 件ウェブページステータス検索Chemie searchBIRD

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4IMI	Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine- tune the Phosphatase Activity of Ssu72. 分子名称: CG14216, CTD, PHOSPHATE ION, ... 著者 Luo, Y, Yogesha, S.D, Zhang, Y. 登録日 2013-01-03 公開日 2013-08-07 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Novel Modifications on C-terminal Domain of RNA Polymerase II Can Fine-tune the Phosphatase Activity of Ssu72. Acs Chem.Biol., 8, 2013
4GWP	Structure of the Mediator Head Module from S. cerevisiae 分子名称: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ... 著者 Robinson, P.J.J, Bushnell, D.A, Trnka, M.J, Burlingame, A.L, Kornberg, R.D. 登録日 2012-09-03 公開日 2012-10-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II. Proc.Natl.Acad.Sci.USA, 109, 2012
3OMW	Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II 分子名称: CG14216 著者 Zhang, Y, Zhang, M, Zhang, Y. 登録日 2010-08-27 公開日 2011-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8701 Å) 主引用文献 Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue. Biochem.J., 434, 2011
2LO6	Structure of Nrd1 CID bound to phosphorylated RNAP II CTD 分子名称: DNA-directed RNA polymerase II subunit RPB1, Protein NRD1 著者 Kubicek, K, Cerna, H, Pasulka, J, Holub, P, Hrossova, D, Loehr, F, Hofr, C, Vanacova, S, Stefl, R. 登録日 2012-01-17 公開日 2012-12-26 最終更新日 2024-11-06 実験手法 SOLUTION NMR 主引用文献 Serine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1. Genes Dev., 26, 2012
5VKO	SPT6 tSH2-RPB1 1468-1500 pT1471, pS1493 分子名称: DNA-directed RNA polymerase II subunit RPB1, ISOPROPYL ALCOHOL, Transcription elongation factor SPT6 著者 Sdano, M.A, Whitby, F.G, Hill, C.P. 登録日 2017-04-21 公開日 2017-09-20 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription. Elife, 6, 2017
5VKL	SPT6 tSH2-RPB1 1476-1500 pS1493 分子名称: DNA-directed RNA polymerase II subunit RPB1, Transcription elongation factor SPT6 著者 Sdano, M.A, Whitby, F.G, Hill, C.P. 登録日 2017-04-21 公開日 2017-10-25 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.198 Å) 主引用文献 A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription. Elife, 6, 2017
3PJP	A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain(CTD) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, Transcription elongation factor SPT6 著者 Sun, M, Lariviere, L, Dengl, S, Mayer, A, Cramer, P. 登録日 2010-11-10 公開日 2010-11-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A tandem SH2 domain in transcription elongation factor Spt6 binds the phosphorylated RNA polymerase II C-terminal repeat domain (CTD). J.Biol.Chem., 285, 2010
7XSE	RNA polymerase II elongation complex transcribing a nucleosome (EC42) 分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... 著者 Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2022-05-13 公開日 2022-09-07 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
7XSX	RNA polymerase II elongation complex transcribing a nucleosome (EC49) 分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... 著者 Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2022-05-15 公開日 2022-09-07 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
7XTD	RNA polymerase II elongation complex transcribing a nucleosome (EC58oct) 分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... 著者 Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2022-05-16 公開日 2022-09-07 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
7XSZ	RNA polymerase II elongation complex transcribing a nucleosome (EC115) 分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... 著者 Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2022-05-15 公開日 2022-09-07 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
7XT7	RNA polymerase II elongation complex transcribing a nucleosome (EC49B) 分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... 著者 Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2022-05-16 公開日 2022-10-12 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
7XTI	RNA polymerase II elongation complex transcribing a nucleosome (EC58hex) 分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... 著者 Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2022-05-17 公開日 2022-10-12 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
7XN7	RNA polymerase II elongation complex containing Spt4/5, Elf1, Spt6, Spn1 and Paf1C 分子名称: Chromatin elongation factor SPT5, Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, ... 著者 Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2022-04-28 公開日 2022-09-07 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
5G5L	RNA polymerase I-Rrn3 complex at 4.8 A resolution 分子名称: DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... 著者 Engel, C, Plitzko, J, Cramer, P. 登録日 2016-05-26 公開日 2016-07-27 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 RNA Polymerase I-Rrn3 Complex at 4.8 A Resolution Nat.Commun., 7, 2016
9II7	RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome containing histone variant H2A.B 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Akatsu, M, Kujirai, T, Rina, H, Ehara, H, Takizawa, Y, Sekine, S, Kurumizaka, H. 登録日 2024-06-19 公開日 2025-06-11 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis of RNAPII transcription on the nucleosome containing histone variant H2A.B. Embo J., 2025
8QEQ	RNA polymerase II bound to minimal Alu RNA right arm in the alternative conformation 分子名称: Alu RNA Minimal Right Arm, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 Tluckova, K, Bernecky, C. 登録日 2023-09-01 公開日 2024-12-11 最終更新日 2025-04-23 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Mechanism of mammalian transcriptional repression by noncoding RNA. Nat.Struct.Mol.Biol., 32, 2025
8QEP	RNA polymerase II bound to Alu RNA right arm 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Tluckova, K, Bernecky, C. 登録日 2023-09-01 公開日 2025-01-22 最終更新日 2025-04-23 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Mechanism of mammalian transcriptional repression by noncoding RNA. Nat.Struct.Mol.Biol., 32, 2025
6QPF	Influenza A virus Polymerase Heterotrimer A/duck/Fujian/01/2002(H5N1) 分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit 著者 Fan, H.T, Keown, J.R, Fodor, E, Grimes, J.M. 登録日 2019-02-13 公開日 2019-09-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.634 Å) 主引用文献 Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
6RR7	Influenza A virus (A/NT/60/1968) polymerase Heterotrimer bound to 3'5' vRNA promoter and capped RNA primer 分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(M7G))-R(P*AP*AP*UP*CP*U)-3'), ... 著者 Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. 登録日 2019-05-17 公開日 2019-09-04 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
6QNW	Influenza A Polymerase Heterotrimer Human H3N2 Northern Territory 1968 分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit 著者 Keown, J.R, Fan, H, Grimes, J.M. 登録日 2019-02-12 公開日 2019-09-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
6QX8	Influenza A virus (A/NT/60/1968) polymerase dimer of heterotrimer in complex with 5' cRNA promoter 分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*CP*AP*AP*AP*AP*GP*CP*AP*GP*A)-3'), ... 著者 Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. 登録日 2019-03-07 公開日 2019-09-04 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.07 Å) 主引用文献 Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
7ZXE	Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) 分子名称: Non-template strand, TATA-box-binding protein, Template strand, ... 著者 Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. 登録日 2022-05-20 公開日 2022-11-30 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
7ZWC	Structure of SNAPc:TBP-TFIIA-TFIIB sub-complex bound to U5 snRNA promoter 分子名称: Non-template strand, TATA-box-binding protein, Template strand, ... 著者 Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. 登録日 2022-05-19 公開日 2022-11-30 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
7NHX	1918 H1N1 Viral influenza polymerase heterotrimer - full transcriptase (Class1) 分子名称: Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-11 公開日 2021-12-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022

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