PDB: 2862 件ウェブページステータス検索Chemie searchBIRD

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8PQL	K48-linked ubiquitin chain formation with a cullin-RING E3 ligase and Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2-donor UB-acceptor UB-SIL1 peptide 分子名称: 5-azanylpentan-2-one, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... 著者 Liwocha, J, Prabu, J.R, Kleiger, G, Schulman, B.A. 登録日 2023-07-11 公開日 2024-02-14 最終更新日 2024-04-17 実験手法 ELECTRON MICROSCOPY (3.76 Å) 主引用文献 Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases. Nat.Struct.Mol.Biol., 31, 2024
8Q7E	Structure of CUL9-RBX1 ubiquitin E3 ligase complex - hexameric assembly 分子名称: Cullin-9, E3 ubiquitin-protein ligase RBX1 著者 Hopf, L.V.M, Horn-Ghetko, D, Schulman, B.A. 登録日 2023-08-16 公開日 2024-04-17 最終更新日 2024-07-31 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nat.Struct.Mol.Biol., 31, 2024
8Q7H	Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused cullin dimer 分子名称: Cullin-9, E3 ubiquitin-protein ligase RBX1, NEDD8, ... 著者 Hopf, L.V.M, Horn-Ghetko, D, Schulman, B.A. 登録日 2023-08-16 公開日 2024-04-17 最終更新日 2024-07-31 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nat.Struct.Mol.Biol., 31, 2024
6OEN	Cryo-EM structure of mouse RAG1/2 PRC complex (DNA1) 分子名称: CALCIUM ION, DNA (46-MER), DNA (57-MER), ... 著者 Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. 登録日 2019-03-27 公開日 2020-01-29 最終更新日 2020-02-26 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
6OEP	Cryo-EM structure of mouse RAG1/2 12RSS-NFC/23RSS-PRC complex (DNA1) 分子名称: CALCIUM ION, DNA (46-MER), DNA (57-MER), ... 著者 Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. 登録日 2019-03-27 公開日 2020-01-29 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
4A0K	STRUCTURE OF DDB1-DDB2-CUL4A-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX 分子名称: 12 BP DNA, 12 BP THF CONTAINING DNA, CULLIN-4A, ... 著者 Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H. 登録日 2011-09-09 公開日 2011-12-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (5.93 Å) 主引用文献 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation. Cell(Cambridge,Mass.), 147, 2011
4A0L	Structure of DDB1-DDB2-CUL4B-RBX1 bound to a 12 bp abasic site containing DNA-duplex 分子名称: 12 BP DNA DUPLEX, 12 BP THF CONTAINING DNA DUPLEX, CULLIN-4B, ... 著者 Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H. 登録日 2011-09-09 公開日 2011-12-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (7.4 Å) 主引用文献 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation. Cell(Cambridge,Mass.), 147, 2011
7O73	Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... 著者 Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. 登録日 2021-04-12 公開日 2021-06-16 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
7O72	Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... 著者 Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. 登録日 2021-04-12 公開日 2021-06-16 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
7O75	Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... 著者 Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. 登録日 2021-04-13 公開日 2021-06-16 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
8OO6	Pol I bound to extended and displaced DNA section - closed conformation 分子名称: DNA polymerase I, Displaced primer, Extending Primer, ... 著者 Botto, M, Borsellini, A, Lamers, M.H. 登録日 2023-04-04 公開日 2023-08-09 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 A four-point molecular handover during Okazaki maturation. Nat.Struct.Mol.Biol., 30, 2023
8OOY	Pol I bound to extended and displaced DNA section - open conformation 分子名称: DNA polymerase I, Displacing Primer, Extending Primer, ... 著者 Botto, M, Borsellini, A, Lamers, M.H. 登録日 2023-04-06 公開日 2023-08-09 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 A four-point molecular handover during Okazaki maturation. Nat.Struct.Mol.Biol., 30, 2023
2RNO	Solution Structure of the N-terminal SAP Domain of SUMO E3 Ligases from Oryza sativa 分子名称: Putative DNA-binding protein 著者 Suzuki, R, Shindo, H, Tase, A, Yamazaki, T. 登録日 2008-01-30 公開日 2008-12-30 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structures and DNA binding properties of the N-terminal SAP domains of SUMO E3 ligases from Saccharomyces cerevisiae and Oryza sativa. Proteins, 75, 2009
4E5Z	Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair 分子名称: AP24 DNA complementary strand, AP24 DNA strand, DNA damage-binding protein 1, ... 著者 Yeh, J.I, Du, S. 登録日 2012-03-15 公開日 2012-08-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.22 Å) 主引用文献 Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair. Proc.Natl.Acad.Sci.USA, 109, 2012
6R7I	Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome 分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... 著者 Faull, S.F, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. 登録日 2019-03-28 公開日 2019-08-28 最終更新日 2019-09-04 実験手法 ELECTRON MICROSCOPY (5.9 Å) 主引用文献 Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
5FQD	Structural basis of Lenalidomide induced CK1a degradation by the crl4crbn ubiquitin ligase 分子名称: CASEIN KINASE I ISOFORM ALPHA, DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, ... 著者 Petzold, G, Fischer, E.S, Thoma, N.H. 登録日 2015-12-09 公開日 2016-02-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural Basis of Lenalidomide-Induced Ck1Alpha Degradation by the Crl4(Crbn) Ubiquitin Ligase. Nature, 532, 2016
4E54	Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair 分子名称: AP24 DNA complementary strand, AP24 DNA strand, DNA damage-binding protein 1, ... 著者 Yeh, J.I, Du, S. 登録日 2012-03-14 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair. Proc.Natl.Acad.Sci.USA, 109, 2012
2ZO1	Mouse NP95 SRA domain DNA specific complex 2 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*DGP*DTP*DCP*DAP*DGP*(5CM)P*DGP*DCP*DAP*DAP*DTP*DGP*DG)-3'), DNA (5'-D(*DTP*DCP*DCP*DAP*DTP*DGP*DCP*DGP*DCP*DTP*DGP*DAP*DC)-3'), ... 著者 Hashimoto, H, Horton, J.R, Cheng, X. 登録日 2008-05-05 公開日 2008-09-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix Nature, 455, 2008
6R7H	Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome 分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... 著者 Faull, S.V, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. 登録日 2019-03-28 公開日 2019-08-28 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (8.8 Å) 主引用文献 Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
3EI2	Structure of hsDDB1-drDDB2 bound to a 16 bp abasic site containing DNA-duplex 分子名称: 5'-D(*DAP*DAP*DAP*DTP*DGP*DAP*DAP*DTP*(3DR)P*DAP*DAP*DGP*DCP*DAP*DGP*DG)-3', 5'-D(*DCP*DCP*DTP*DGP*DCP*DTP*DTP*DTP*DAP*DTP*DTP*DCP*DAP*DTP*DTP*DT)-3', DNA damage-binding protein 1, ... 著者 Scrima, A, Thoma, N.H. 登録日 2008-09-15 公開日 2009-01-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell(Cambridge,Mass.), 135, 2008
3EI1	Structure of hsDDB1-drDDB2 bound to a 14 bp 6-4 photoproduct containing DNA-duplex 分子名称: 5'-D(*DAP*DCP*DGP*DCP*DGP*DAP*(64T)P*(5PY)P*DGP*DCP*DGP*DCP*DCP*DC)-3', 5'-D(*DTP*DGP*DGP*DGP*DCP*DGP*DCP*DAP*DAP*DTP*DCP*DGP*DCP*DG)-3', DNA damage-binding protein 1, ... 著者 Scrima, A, Thoma, N.H. 登録日 2008-09-15 公開日 2009-01-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell(Cambridge,Mass.), 135, 2008
4R1M	Crystal structure of a Putative Acyl-CoA ligase (BT_0428) from Bacteroides thetaiotaomicron VPI-5482 at 2.48 A resolution 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2014-08-06 公開日 2014-08-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Crystal structure of a Hypothetical Acyl-CoA ligase (BT_0428) from Bacteroides thetaiotaomicron VPI-5482 at 2.48 A resolution To be published
4R1L	Crystal structure of a Putative Acyl-CoA ligase (BT_0428) from Bacteroides thetaiotaomicron VPI-5482 at 2.42 A resolution 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2014-08-06 公開日 2014-08-27 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Crystal structure of a Hypothetical Acyl-CoA ligase (BT_0428) from Bacteroides thetaiotaomicron VPI-5482 at 2.42 A resolution To be published
4RVO	Crystal structure of a Putative Acyl-CoA ligase (BT_0428) from Bacteroides thetaiotaomicron VPI-5482 at 2.41 A resolution 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2014-11-26 公開日 2014-12-31 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Crystal structure of a Putative Acyl-CoA ligase (BT_0428) from Bacteroides thetaiotaomicron VPI-5482 at 2.41 A resolution To be published
8WQR	Structure of the DDB1-AMBRA1 E3 ligase receptor complex linked to cell cycle regulation 分子名称: Activating molecule in BECN1-regulated autophagy protein 1, DNA damage-binding protein 1 著者 Liu, M, Wang, Y, Su, M.Y, Stjepanovic, G. 登録日 2023-10-12 公開日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.08 Å) 主引用文献 Structure of the DDB1-AMBRA1 E3 ligase receptor complex linked to cell cycle regulation. Nat Commun, 14, 2023

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