3ENZ
 
 | | Arsenolytic structure of Plasmodium falciparum purine nucleoside phosphorylase with hypoxanthine, ribose and arsenate ion | | 分子名称: | 1,4-anhydro-D-ribitol, ARSENATE, FORMIC ACID, ... | | 著者 | Chaikuad, A, Brady, R.L. | | 登録日 | 2008-09-26 | | 公開日 | 2009-08-04 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases.
Bmc Struct.Biol., 9, 2009
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4F3C
 | | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with butyl-thio-DADMe-Immucillin-A | | 分子名称: | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol, 1,2-ETHANEDIOL, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | | 著者 | Haapalainen, A.M, Thomas, K, Bonanno, J.B, Almo, S.C, Schramm, V.L. | | 登録日 | 2012-05-09 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with butyl-thio-DADMe-Immucillin-A
Structure, 21, 2013
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4F2P
 | | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with diEtglycol-thio-DADMe-Immucillin-A | | 分子名称: | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-({[2-(2-hydroxyethoxy)ethyl]sulfanyl}methyl)pyrrolidin-3- ol, 1,2-ETHANEDIOL, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ... | | 著者 | Haapalainen, A.M, Thomas, K, Bonanno, J.B, Almo, S.C, Schramm, V.L. | | 登録日 | 2012-05-08 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with diEtglycol-thio-DADMe-Immucillin-A
Structure, 21, 2013
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4F1W
 | | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with Adenine | | 分子名称: | 1,2-ETHANEDIOL, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE, ... | | 著者 | Haapalainen, A.M, Thomas, K, Bonanno, J.B, Almo, S.C, Schramm, V.L. | | 登録日 | 2012-05-07 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with Adenine
Structure, 21, 2013
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4F2W
 | | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with methyl-thio-DADMe-Immucillin-A | | 分子名称: | (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL, 1,2-ETHANEDIOL, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ... | | 著者 | Haapalainen, A.M, Thomas, K, Bonanno, J.B, Almo, S.C, Schramm, V.L. | | 登録日 | 2012-05-08 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with methyl-thio-DADMe-Immucillin-A
Structure, 21, 2013
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4F3K
 | | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with homocysteine-DADMe-Immucillin-A | | 分子名称: | 1,2-ETHANEDIOL, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, {(3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-hydroxypyrrolidin-3-yl}-L-methionine | | 著者 | Haapalainen, A.M, Thomas, K, Bonanno, J.B, Almo, S.C, Schramm, V.L. | | 登録日 | 2012-05-09 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with homocysteine-DADMe-Immucillin-A
Structure, 21, 2013
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3BJE
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4WKB
 | | Crystal structure of Vibrio cholerae 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with methylthio-DADMe-Immucillin-A | | 分子名称: | (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | | 著者 | Cameron, S.A, Thomas, K, Almo, S.C, Schramm, V.L. | | 登録日 | 2014-10-02 | | 公開日 | 2015-08-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Active site and remote contributions to catalysis in methylthioadenosine nucleosidases.
Biochemistry, 54, 2015
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4WKC
 | | Crystal structure of Escherichia coli 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with butylthio-DADMe-Immucillin-A | | 分子名称: | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, TETRAETHYLENE GLYCOL | | 著者 | Cameron, S.A, Thomas, K, Almo, S.C, Schramm, V.L. | | 登録日 | 2014-10-02 | | 公開日 | 2015-08-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Active site and remote contributions to catalysis in methylthioadenosine nucleosidases.
Biochemistry, 54, 2015
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4X24
 | | Crystal structure of Vibrio cholerae 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with methylthio-DADMe-Immucillin-A | | 分子名称: | (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, TRIETHYLENE GLYCOL | | 著者 | Cameron, S.A, Thomas, K, Almo, S.C, Schramm, V.L. | | 登録日 | 2014-11-25 | | 公開日 | 2015-08-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Active site and remote contributions to catalysis in methylthioadenosine nucleosidases.
Biochemistry, 54, 2015
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3DP9
 | | Crystal structure of Vibrio cholerae 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with butylthio-DADMe-Immucillin A | | 分子名称: | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol, IODIDE ION, MTA/SAH nucleosidase | | 著者 | Ho, M, Gutierrez, J.A, Crowder, T, Rinaldo-Matthis, A, Almo, S.C, Schramm, V.L. | | 登録日 | 2008-07-07 | | 公開日 | 2009-03-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
Nat.Chem.Biol., 5, 2009
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4KPN
 | | Plant nucleoside hydrolase - PpNRh1 enzyme | | 分子名称: | CALCIUM ION, Nucleoside N-ribohydrolase 1 | | 著者 | Morera, S, Vigouroux, A, Kopecny, D. | | 登録日 | 2013-05-14 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Structure and Function of Nucleoside Hydrolases from Physcomitrella patens and Maize Catalyzing the Hydrolysis of Purine, Pyrimidine, and Cytokinin Ribosides.
Plant Physiol., 163, 2013
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3ZTP
 | | Orthorhombic crystal form P21212 of the Aquifex aeolicus nucleoside diphosphate kinase | | 分子名称: | GLYCEROL, NUCLEOSIDE DIPHOSPHATE KINASE, SULFATE ION | | 著者 | Boissier, F, Georgescauld, F, Moynie, L, Dupuy, J.-W, Sarger, C, Podar, M, Lascu, I, Giraud, M.-F, Dautant, A. | | 登録日 | 2011-07-12 | | 公開日 | 2012-03-14 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | An Intersubunit Disulfide Bridge Stabilizes the Tetrameric Nucleoside Diphosphate Kinase of Aquifex Aeolicus.
Proteins, 80, 2012
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4C6A
 | | High Resolution Structure of the Nucleoside diphosphate kinase | | 分子名称: | DI(HYDROXYETHYL)ETHER, NUCLEOSIDE DIPHOSPHATE KINASE, CYTOSOLIC | | 著者 | Priet, S, Ferron, F, Alvarez, K, Verron, M, Canard, B. | | 登録日 | 2013-09-18 | | 公開日 | 2013-11-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Enzymatic Synthesis of Acyclic Nucleoside Thiophosphonate Diphosphates: Effect of the Alpha-Phosphorus Configuration on HIV-1 RT Activity.
Antiviral Res., 117, 2015
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8RO0
 | | Structure of the C. elegans Intron Lariat Spliceosome primed for disassembly (ILS') | | 分子名称: | Cell division cycle 5-like protein, Coiled-coil domain-containing protein 12, GCF C-terminal domain-containing protein, ... | | 著者 | Vorlaender, M.K, Rothe, P, Plaschka, C. | | 登録日 | 2024-01-11 | | 公開日 | 2024-08-07 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Mechanism for the initiation of spliceosome disassembly.
Nature, 632, 2024
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8RO1
 | | Structure of the C. elegans Intron Lariat Spliceosome double-primed for disassembly (ILS'') | | 分子名称: | CWF19-like protein 1 homolog, CWF19-like protein 2 homolog, Cell division cycle 5-like protein, ... | | 著者 | Vorlaender, M.K, Rothe, P, Plaschka, C. | | 登録日 | 2024-01-11 | | 公開日 | 2024-08-07 | | 最終更新日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanism for the initiation of spliceosome disassembly.
Nature, 632, 2024
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8DB9
 | | Adenosine/guanosine nucleoside hydrolase bound to inhibitor | | 分子名称: | 1-beta-D-ribofuranosyl-1H-1,2,4-triazole-3-carboximidamide, CALCIUM ION, Inosine-uridine preferring nucleoside hydrolase family protein | | 著者 | Muellers, S.N, Allen, K.N, Stockman, B.J. | | 登録日 | 2022-06-14 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structure-Guided Insight into the Specificity and Mechanism of a Parasitic Nucleoside Hydrolase.
Biochemistry, 61, 2022
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8DB6
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8DB8
 | | Adenosine/guanosine nucleoside hydrolase bound to ImH | | 分子名称: | 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, CALCIUM ION, Inosine-uridine preferring nucleoside hydrolase family protein | | 著者 | Muellers, S.N, Allen, K.N, Stockman, B.J. | | 登録日 | 2022-06-14 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structure-Guided Insight into the Specificity and Mechanism of a Parasitic Nucleoside Hydrolase.
Biochemistry, 61, 2022
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8DB7
 | | Adenosine/guanosine nucleoside hydrolase bound to a fragment inhibitor | | 分子名称: | CALCIUM ION, GLYCEROL, Inosine-uridine preferring nucleoside hydrolase family protein, ... | | 著者 | Muellers, S.N, Allen, K.N, Stockman, B.J. | | 登録日 | 2022-06-14 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Structure-Guided Insight into the Specificity and Mechanism of a Parasitic Nucleoside Hydrolase.
Biochemistry, 61, 2022
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5NRL
 | | Structure of a pre-catalytic spliceosome | | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... | | 著者 | Plaschka, C, Lin, P.-C, Nagai, K. | | 登録日 | 2017-04-24 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | | 主引用文献 | Structure of a pre-catalytic spliceosome.
Nature, 546, 2017
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3OPV
 | | Crystal structure of E. Coli purine nucleoside phosphorylase Arg24Ala mutant | | 分子名称: | PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type | | 著者 | Mikleusevic, G, Stefanic, Z, Narzyk, M, Wielgus-Kutrowska, B, Bzowska, A, Luic, M. | | 登録日 | 2010-09-02 | | 公開日 | 2011-07-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies.
Biochimie, 93, 2011
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3OOE
 | | Crystal structure of E. Coli purine nucleoside phosphorylase with PO4 | | 分子名称: | PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type | | 著者 | Mikleusevic, G, Stefanic, Z, Narzyk, M, Wielgus-Kutrowska, B, Bzowska, A, Luic, M. | | 登録日 | 2010-08-31 | | 公開日 | 2011-07-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies.
Biochimie, 93, 2011
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5O9G
 | | Structure of nucleosome-Chd1 complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... | | 著者 | Farnung, L, Vos, S.M, Wigge, C, Cramer, P. | | 登録日 | 2017-06-19 | | 公開日 | 2017-10-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Nucleosome-Chd1 structure and implications for chromatin remodelling.
Nature, 550, 2017
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3IOM
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