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3J3T
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Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
分子名称: Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
著者Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N.
登録日2013-04-18
公開日2013-05-15
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3K0S
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BU of 3k0s by Molmil
Crystal structure of E.coli DNA mismatch repair protein MutS, D693N mutant, in complex with GT mismatched DNA
分子名称: 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP*CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP*CP*CP*TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP*GP*AP*C*AP*CP*T*GP*GP*TP*GP*CP*TP*TP*GP*GP*CP*AP*GP*CP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ...
著者Reumer, G.A, Winterwerp, H.H.K, Sixma, T.K.
登録日2009-09-25
公開日2010-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Magnesium coordination controls the molecular switch function of DNA mismatch repair protein MutS.
J.Biol.Chem., 285, 2010
2MPE
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BU of 2mpe by Molmil
Solution NMR structure for B. pseudomallei BPSL1050
分子名称: BPSL1050
著者Gaudesi, D, Musco, G, Quilici, G.
登録日2014-05-15
公開日2015-03-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure-Based Design of a B Cell Antigen from B. pseudomallei.
Acs Chem.Biol., 10, 2015
7KA2
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BU of 7ka2 by Molmil
Aldolase, rabbit muscle (beam-tilt refinement x2)
分子名称: Fructose-bisphosphate aldolase A
著者Kearns, S.K, Cash, J.N, Cianfrocco, M.A, Li, Y.
登録日2020-09-29
公開日2020-12-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献High-resolution cryo-EM using beam-image shift at 200 keV.
Iucrj, 7, 2020
7C08
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BU of 7c08 by Molmil
Crystal structure of S34Y mutant of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU.
分子名称: RNA (5'-R(*U*UP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ...
著者Yoshida, H, Park, S.Y, Urano, T, Obayashi, E.
登録日2020-04-30
公開日2020-09-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1.
Nat Commun, 11, 2020
3K1Y
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BU of 3k1y by Molmil
X-ray structure of oxidoreductase from corynebacterium diphtheriae. orthorombic crystal form, northeast structural genomics consortium target cdr100d
分子名称: SULFATE ION, oxidoreductase
著者Kuzin, A, Lew, S, Sahdev, S, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2009-09-29
公開日2009-10-20
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Northeast Structural Genomics Consortium Target CdR100D
To be Published
7BTH
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BU of 7bth by Molmil
Mevo lectin- Native form-1
分子名称: GLYCEROL, lectin
著者Sivaji, N, Suguna, K, Surolia, A, Vijayan, M.
登録日2020-04-01
公開日2021-02-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and related studies on Mevo lectin from Methanococcus voltae A3: the first thorough characterization of an archeal lectin and its interactions.
Glycobiology, 31, 2021
3J4U
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BU of 3j4u by Molmil
A new topology of the HK97-like fold revealed in Bordetella bacteriophage: non-covalent chainmail secured by jellyrolls
分子名称: cementing protein, major capsid protein
著者Zhang, X, Guo, H, Jin, L, Czornyj, E, Hodes, A, Hui, W.H, Nieh, A.W, Miller, J.F, Zhou, Z.H.
登録日2013-10-09
公開日2013-12-25
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 A resolution.
Elife, 2, 2013
3ADB
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BU of 3adb by Molmil
Crystal structure of O-phosphoseryl-tRNA kinase complexed with selenocysteine tRNA and AMPPNP (crystal type 1)
分子名称: L-seryl-tRNA(Sec) kinase, MAGNESIUM ION, PHOSPHATE ION, ...
著者Itoh, Y, Chiba, S, Sekine, S, Yokoyama, S.
登録日2010-01-18
公開日2010-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for the Major Role of O-Phosphoseryl-tRNA Kinase in the UGA-Specific Encoding of Selenocysteine
Mol.Cell, 39, 2010
7QUZ
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BU of 7quz by Molmil
Crystal structure of the SeMet octameric C-terminal Big_2-CBM56 domains from Paenibacillus illinoisensis (Bacillus circulans IAM1165) beta-1,3-glucanase H
分子名称: Beta-1,3-glucanase bglH, CHLORIDE ION, GLYCEROL
著者Najmudin, S, Venditto, I, Fontes, C.M.G.A, Bule, P.
登録日2022-01-19
公開日2023-02-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.156 Å)
主引用文献Structural and biochemical characterization of C-terminal Big_2-CBM56 domains of Bacillus circulans IAM1165 beta-1,3-glucanase H and Paenibacillus sp CBM56
To be published
7TL4
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BU of 7tl4 by Molmil
Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 6YF
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
著者Blee, A.M, Salay, L.E, Chazin, W.J.
登録日2022-01-18
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.805 Å)
主引用文献Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
8RNT
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BU of 8rnt by Molmil
STRUCTURE OF RIBONUCLEASE T1 COMPLEXED WITH ZINC(II) AT 1.8 ANGSTROMS RESOLUTION: A ZN2+.6H2O.CARBOXYLATE CLATHRATE
分子名称: RIBONUCLEASE T1, ZINC ION
著者Ding, J, Choe, H.-W, Granzin, J, Saenger, W.
登録日1991-09-23
公開日1993-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of ribonuclease T1 complexed with zinc(II) at 1.8 A resolution: a Zn2+.6H2O.carboxylate clathrate.
Acta Crystallogr.,Sect.B, 48, 1992
7BTX
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BU of 7btx by Molmil
The mitochondrial SAM-Mdm10 supercomplex in GDN micelle from S.cere
分子名称: MDM10 isoform 1, Mitochondrial outer membrane beta-barrel protein, Sorting assembly machinery 35 kDa subunit, ...
著者Takeda, H, Tsutsumi, A, Nishizawa, T, Nureki, O, Kikkawa, M, Endo, T.
登録日2020-04-03
公開日2021-01-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mitochondrial sorting and assembly machinery operates by beta-barrel switching.
Nature, 590, 2021
5M45
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BU of 5m45 by Molmil
Structure of Acetone Carboxylase purified from Xanthobacter autotrophicus
分子名称: 3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL, ACETATE ION, ADENOSINE MONOPHOSPHATE, ...
著者Kabasakal, B.V, Wells, J.N, Nwaobi, B.C, Eilers, B.J, Peters, J.W, Murray, J.W.
登録日2016-10-18
公開日2017-08-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation.
Sci Rep, 7, 2017
7U51
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BU of 7u51 by Molmil
Nucleosome core particle with AP-site at SHL-6
分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, ...
著者Freudenthal, B.D, Weaver, T.M.
登録日2022-03-01
公開日2022-09-07
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for APE1 processing DNA damage in the nucleosome.
Nat Commun, 13, 2022
7F91
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SeMet derivative of Thrombocorticin
分子名称: Thrombocorticin
著者Kageyama, H, Onodera, K, Sakai, R, Tanaka, Y.
登録日2021-07-03
公開日2022-07-06
最終更新日2023-07-19
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activation.
Nat Commun, 13, 2022
3J6G
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BU of 3j6g by Molmil
Minimized average structure of microtubules stabilized by taxol
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E.
登録日2014-02-19
公開日2014-06-04
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (5.5 Å)
主引用文献High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
8QCP
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BU of 8qcp by Molmil
Tau - AD-LIA8 (tau intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-28
公開日2023-09-06
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
2IZY
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BU of 2izy by Molmil
Molecular Basis of AKAP Specificity for PKA Regulatory Subunits
分子名称: CAMP-DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT II
著者Gold, M.G, Lygren, B, Dokurno, P, Hoshi, N, McConnachie, G, Tasken, K, Carlson, C.R, Scott, J.D, Barford, D.
登録日2006-07-27
公開日2006-11-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular Basis of Akap Specificity for Pka Regululatory Subunits
Mol.Cell, 24, 2006
8QJJ
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BU of 8qjj by Molmil
CTE type II (tau intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W.
登録日2023-09-13
公開日2023-10-18
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
7JN1
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BU of 7jn1 by Molmil
Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 3
分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein
著者Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L.
登録日2020-08-03
公開日2020-09-09
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
7F60
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Crystal structure of auxiliary protein in complex with human nuclear protein
分子名称: Nuclear pore complex protein Nup98-Nup96, ORF6 protein, mRNA export factor
著者Gao, X, Cui, S.
登録日2021-06-23
公開日2022-09-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural basis for Sarbecovirus ORF6 mediated blockage of nucleocytoplasmic transport
Nat Commun, 13, 2022
7QWN
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BU of 7qwn by Molmil
Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor
分子名称: CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
著者Snee, M, Katariya, M, Levy, C, Leys, D.
登録日2022-01-25
公開日2023-02-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis.
Chemistry, 29, 2023
5LDP
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BU of 5ldp by Molmil
Crystal structure of E.coli LigT complexed with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
著者Myllykoski, M, Kursula, P.
登録日2016-06-27
公開日2017-01-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural aspects of nucleotide ligand binding by a bacterial 2H phosphoesterase.
PLoS ONE, 12, 2017
8QKB
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Crystal structure of human cathepsin L in complex with the vinyl sulfone inhibitor K777
分子名称: 1,2-ETHANEDIOL, Cathepsin L, DI(HYDROXYETHYL)ETHER, ...
著者Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A.
登録日2023-09-14
公開日2023-09-27
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors.
J.Med.Chem., 67, 2024

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