PDB: 47011 件ウェブページステータス検索Chemie searchBIRD

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7RBN	Human DNA polymerase beta crosslinked complex, 20 min Ca to Mg exchange 分子名称: 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol, DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... 著者 Kumar, A. 登録日 2021-07-06 公開日 2022-03-09 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Interlocking activities of DNA polymerase beta in the base excision repair pathway. Proc.Natl.Acad.Sci.USA, 119, 2022
7RBH	Human DNA polymerase beta crosslinked ternary complex 2 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol, CALCIUM ION, ... 著者 Kumar, A. 登録日 2021-07-06 公開日 2022-03-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Interlocking activities of DNA polymerase beta in the base excision repair pathway. Proc.Natl.Acad.Sci.USA, 119, 2022
7RBL	Human DNA polymerase beta crosslinked complex, 60 s Ca to Mg exchange 分子名称: 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), DNA (5'-D(*GP*TP*CP*GP*G)-3'), ... 著者 Kumar, A. 登録日 2021-07-06 公開日 2022-03-09 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Interlocking activities of DNA polymerase beta in the base excision repair pathway. Proc.Natl.Acad.Sci.USA, 119, 2022
7RBF	Human DNA polymerase beta crosslinked binary complex - B 分子名称: 1,2-ETHANEDIOL, 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol, DI(HYDROXYETHYL)ETHER, ... 著者 Reed, A.J, Kumar, A. 登録日 2021-07-06 公開日 2022-03-09 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Interlocking activities of DNA polymerase beta in the base excision repair pathway. Proc.Natl.Acad.Sci.USA, 119, 2022
7RBJ	Human DNA polymerase beta crosslinked complex, 30 s Ca to Mg exchange 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), ... 著者 Kumar, A. 登録日 2021-07-06 公開日 2022-03-09 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Interlocking activities of DNA polymerase beta in the base excision repair pathway. Proc.Natl.Acad.Sci.USA, 119, 2022
7RBM	Human DNA polymerase beta crosslinked complex, 60 s Ca to Mn exchange 分子名称: 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol, DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), ... 著者 Kumar, A. 登録日 2021-07-06 公開日 2022-03-09 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Interlocking activities of DNA polymerase beta in the base excision repair pathway. Proc.Natl.Acad.Sci.USA, 119, 2022
4ZTZ	Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*AP*GP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), ... 著者 Szymanski, M.R, Yin, Y.W. 登録日 2015-05-15 公開日 2015-09-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.442 Å) 主引用文献 Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase EMBO J., 34, 2015
5D5X	Crystal structure of Chaetomium thermophilum Skn7 with SSRE DNA 分子名称: Putative transcription factor, SSRE DNA strand 1, SSRE DNA strand 2 著者 Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. 登録日 2015-08-11 公開日 2015-12-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
4IHS	Crystal Structure of BenM_DBD/catB site 1 DNA Complex 分子名称: HTH-type transcriptional regulator BenM, MALONATE ION, SODIUM ION, ... 著者 Alanazi, A, Momany, C, Neidle, E.L. 登録日 2012-12-19 公開日 2013-07-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The DNA-binding domain of BenM reveals the structural basis for the recognition of a T-N11-A sequence motif by LysR-type transcriptional regulators. Acta Crystallogr.,Sect.D, 69, 2013
8D37	Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in replication conformer 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (25-MER), ... 著者 Park, J, Yin, Y.W. 登録日 2022-05-31 公開日 2023-05-24 最終更新日 2023-07-05 実験手法 ELECTRON MICROSCOPY (2.65 Å) 主引用文献 Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity. Nat.Struct.Mol.Biol., 30, 2023
8D33	Human mitochondrial DNA polymerase gamma ternary complex with GC basepair 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (25-MER), ... 著者 Park, J, Yin, Y.W. 登録日 2022-05-31 公開日 2023-05-24 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (2.46 Å) 主引用文献 Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity. Nat.Struct.Mol.Biol., 30, 2023
8D3R	Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in intermediate conformer 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*TP*AP*T)-3'), ... 著者 Park, J, Yin, Y.W. 登録日 2022-06-01 公開日 2023-05-24 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity. Nat.Struct.Mol.Biol., 30, 2023
8D42	Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in editing conformer (composite) 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*TP*AP*T)-3'), ... 著者 Park, J, Yin, Y.W. 登録日 2022-06-01 公開日 2023-05-24 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (2.91 Å) 主引用文献 Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity. Nat.Struct.Mol.Biol., 30, 2023
4IHT	Crystal Structure of BenM_DBD/benA site 1 DNA Complex 分子名称: HTH-type transcriptional regulator BenM, benA site 1 DNA, benA site 1 DNA - complement 著者 Alanazi, A, Momany, C, Neidle, E.L. 登録日 2012-12-19 公開日 2013-07-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The DNA-binding domain of BenM reveals the structural basis for the recognition of a T-N11-A sequence motif by LysR-type transcriptional regulators. Acta Crystallogr.,Sect.D, 69, 2013
8F6B	Crystal structure of murine PolG2 hexamer bound to DNA 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, DNA (5'-D(*CP*TP*GP*GP*TP*AP*GP*GP*CP*GP*CP*CP*TP*AP*CP*CP*AP*G)-3'), ... 著者 Wojtaszek, J.L, Hoff, K.E, Williams, R.S. 登録日 2022-11-16 公開日 2023-08-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA. Nucleic Acids Res., 51, 2023
8F69	Crystal structure of murine PolG2 dimer bound to DNA 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... 著者 Wojtaszek, J.L, Hoff, K.E, Williams, R.S. 登録日 2022-11-16 公開日 2023-08-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA. Nucleic Acids Res., 51, 2023
5D5W	Crystal structure of Chaetomium thermophilum Skn7 with HSE DNA 分子名称: HSE DNA, Putative transcription factor 著者 Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. 登録日 2015-08-11 公開日 2015-12-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
4WUZ	Crystal structure of lambda exonuclease in complex with DNA and Ca2+ 分子名称: CALCIUM ION, DNA (5'-D(*TP*T*TP*CP*GP*GP*TP*AP*CP*AP*GP*TP*AP*G)-3'), DNA (5'-D(P*AP*GP*CP*TP*AP*CP*TP*GP*TP*AP*CP*CP*GP*A)-3'), ... 著者 Zhang, J, Bell, C.E. 登録日 2014-11-04 公開日 2014-11-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Crystal Structure of lambda Exonuclease in Complex with DNA and Ca(2+). Biochemistry, 53, 2014
2XRO	Crystal structure of TtgV in complex with its DNA operator 分子名称: HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGV, OSMIUM ION, TTGV OPERATOR DNA 著者 Lu, D, Fillet, S, Meng, C, Alguel, Y, Kloppsteck, P, Bergeron, J, Krell, T, Gallegos, M.-T, Ramos, J, Zhang, X. 登録日 2010-09-17 公開日 2010-12-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Crystal Structure of Ttgv in Complex with its DNA Operator Reveals a General Model for Cooperative DNA Binding of Tetrameric Gene Regulators. Genes Dev., 24, 2010
1HLZ	CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA-BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT 分子名称: 5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*TP*AP*GP*GP*TP*CP*AP*G)-3', 5'-D(*CP*TP*GP*AP*CP*CP*TP*AP*GP*TP*GP*AP*CP*CP*TP*AP*GP*TP*TP*G)-3', ORPHAN NUCLEAR RECEPTOR NR1D1, ... 著者 Sierk, M.L, Zhao, Q, Rastinejad, F. 登録日 2000-12-04 公開日 2001-11-16 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 DNA Deformability as a Recognition Feature in the RevErb Response Element Biochemistry, 40, 2001
8G9O	Complete DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... 著者 Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. 登録日 2023-02-21 公開日 2023-04-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
6KRH	Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis 分子名称: ADENOSINE MONOPHOSPHATE, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase A, ... 著者 Ramachandran, R, Shukla, A, Afsar, M. 登録日 2019-08-21 公開日 2020-08-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Salt bridges at the subdomain interfaces of the adenylation domain and active-site residues of Mycobacterium tuberculosis NAD + -dependent DNA ligase A (MtbLigA) are important for the initial steps of nick-sealing activity. Acta Crystallogr D Struct Biol, 77, 2021
7K04	Structure of TFIIH/Rad4-Rad23-Rad33/DNA in DNA opening 分子名称: CALCIUM ION, DNA repair helicase RAD25, DNA repair helicase RAD3, ... 著者 van Eeuwen, T, Min, J.H, Murakami, K. 登録日 2020-09-03 公開日 2021-07-28 実験手法 ELECTRON MICROSCOPY (9.25 Å) 主引用文献 Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair. Nat Commun, 12, 2021
4TUS	Human DNA polymerase beta inserting dCMPNPP opposite the 5'G of cisplatin crosslinked Gs (Pt-GG2) WITH MANGANESE IN THE ACTIVE SITE. 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ... 著者 Koag, M.C, Lee, S. 登録日 2014-06-24 公開日 2014-10-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Structural Basis for the Inefficient Nucleotide Incorporation Opposite Cisplatin-DNA Lesion by Human DNA Polymerase beta. J.Biol.Chem., 289, 2014
1L9Z	Thermus aquaticus RNA Polymerase Holoenzyme/Fork-Junction Promoter DNA Complex at 6.5 A Resolution 分子名称: MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ... 著者 Murakami, K.S, Masuda, S, Campbell, E.A, Muzzin, O, Darst, S.A. 登録日 2002-03-27 公開日 2002-05-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (6.5 Å) 主引用文献 Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex. Science, 296, 2002

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